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The long awaited results are finally in from the Tick Project, which tested two different environmentally safe tick treatments in suburban yards to see if they reduced deer tick numbers and the incidence of tick-borne diseases in people and pets. Unfortunately, the results of this multi-year project (2017 to 2020) are not as good as hoped.

What they did: The Tick Project was a four year study in 24 New York neighborhoods with a high incidence of Lyme disease. They tested 2 products - either together or separately, as well as having yards that were not treated (the placebo group).

One treatment was spraying Met52 on low vegetation. This spray is made up of water and the fungi Metarhizium brunneum (formerly Metarhizium anisopliae), which is naturally found in forest soils and is non-toxic to humans and pets. Studies had shown that ticks die within 3 to 7 days after being exposed to Met52.

Tick Control System (TCS) Credit: The Tick Project

Tick bait boxes placed on properties was the second treatment tested. The Tick Control system or TCS is a small bait box that attracts rodents. When an animal enters the box, it receives a small dose of fipronil, the active ingredient in many tick treatments used on dogs and cats. Fipronil kills ticks on animals like chipmunks and mice, which are largely responsible for infecting ticks with the Lyme bacterium.

Results: The researchers found that the numbers of ticks decreased by about half on the properties with the TCS bait boxes, but found no reduction in tick numbers from the Met52 fungal spray. Unfortunately, there were just as many cases of tick borne diseases in the humans living on properties treated with either treatment (when compared to no treatment).

Even though human encounters with ticks was about 20% lower in neighborhoods treated with both treatments, the difference was not statistically significant. But you can say it was trending that way.

However, the incidence of tick-borne disease in pets went down significantly, lower by about half - on properties treated with either treatment or both treatments. ...continue reading "Reducing Tick Numbers Is Tough"

Deer tick Credit: Wikipedia

Summer is here, people are spending outdoors, and so there is concern about ticks and the diseases that they carry. New research (an analysis of existing data and studies) determined that more than 14% of the world's population now has or had Lyme disease (Lyme borreliosis)! They can tell from antibodies in the blood. Yikes!

Here in the United States people tend to think of Lyme disease as an increasingly common disease spreading from the northeast US to other parts of the country. But in reality the incidence of the tick-borne disease is highest in central and western Europe, as well as eastern Asia. In fact, Lyme disease or Borrelia burgdorferi (Bb) infection is the most frequent tick transmitted disease world wide.

The researchers found that some factors associated with higher incidence of Lyme disease is being male, 50 years and older, living in a rural area, and having had tick bites. In the northeast US infected deer ticks (Ixodes scapularis) are responsible for most cases of Lyme disease. [Other Lyme disease and tick articles, including treatments and controls.]

From Medical Xpress: More than 14% of world's population likely has (had) tick-borne Lyme disease

More than 14% of the world's population probably has, or has had, tick-borne Lyme disease, as indicated by the presence of antibodies in the blood, reveals a pooled data analysis of the available evidence, published in the open access journal BMJ Global Health.  ...continue reading "Lyme Disease Is Common Throughout Parts of the World"

Well, these were surprising study results, given that so many studies find that eating fish has such beneficial health effects. A recent large study of US adults found that higher fish consumption was associated with melanoma (when compared to persons who hardly eat fish).

Brown School of Health researchers found that a higher intake of fish (all kinds), tuna, and non-fried fish were all associated with a higher risk  of both malignant melanoma and melanoma in situ (stage 0). Interestingly, fried fish intake was inversely associated with risk of malignant melanoma - that is, the more fried fish is eaten, the lower the risk of melanoma.

The group with the highest fish intake ate about 10 ounces per week or 3 servings, and had about 22% higher rate of melanoma.

They speculate that this cancer association could be due to the contaminants in fish, such as PCBs, dioxins, arsenic, and mercury. Other research has found that higher fish intake is associated with higher levels of these contaminants in the body, and that there are associations between these contaminants and a higher risk of skin cancer.

But the researchers also said people should keep eating fish for all their other health benefits (e.g., for heart health). In other words, don't panic. There are other known risk factors for melanoma such as repeated sunburns in childhood.

From Science Daily: Higher fish consumption may be associated with increased melanoma risk

Eating higher levels of fish, including tuna and non-fried fish, appears to be associated with a greater risk of malignant melanoma, suggests a large study of US adults published in Cancer Causes & Control. ...continue reading "High Fish Intake and Melanoma"

Chromosomes, incl. XXY (Klinefelter Syndrome). Credit: Wikipedia

A recent study from the UK of more than 207,000 adult men revealed something surprising - about 1 in 500 men did not have the typical XY sex chromosomes, but instead have XXY (Klinefelter Syndrome) or XYY. And only 23% of those with XXY and 0.7% with XYY actually knew it or this was recorded in their medical records!

This means that most of the men did not have any obvious reason to do genetic screening. The men, all of European ancestry and between the age of 40 and 70 years, participated in the UK Biobank (so these adults were considered healthier than the general public).

One finding is that the XYY and XXY men tended to have more health problems than typical XY men, more lived alone or without a partner than XY men, and more reported loneliness.

Some of the XXY men had received the XXY diagnosis during adolescence for delayed puberty, or later for infertility or lower testosterone levels. Other features can include tall adult stature, high body fat percentage, poor muscle tone, low bone mineral density, and increased risks of neurocognitive disability, psychoses, and disorders of personality.

On the other hand, XYY men tended  to have normal sexual development and fertility. Features can include being tall, scoliosis, learning difficulties, poor muscle tone, increased central fat (abdominal fat), seizures, asthma, and emotional and behavioral problems (e.g., attention deficit disorder).

But what was surprising was that both XXY and XYY men were similarly at higher risk for several conditions: type 2 diabetes, venous thrombosis, pulmonary embolism, and chronic obstructive pulmonary disease. [See tables in study.]

Even though XXY and XYY can result in learning difficulties, also note that while 40.4% of XY men had graduated college, 16.3% of XXY, and 20.2% of XYY also had. In other words, there are heightened risks of certain problems (including diseases), but that doesn't mean it definitely results in problems. As the researchers point out: there are increased risks of "potentially preventable diseases", including the "metabolic and vascular diseases".

One question comes to mind: If there is no obvious reason, should a person (even babies) receive genetic screening to see what their sex chromosomes are? Does everyone really want to know? Is there really a need to always know by the person or others? Employers? To be labeled by insurance companies? Especially if there is no obvious reason to test.

From Medical Xpress: One in 500 men carry extra sex chromosome, putting them at higher risk of several common diseases

Around one in 500 men could be carrying an extra X or Y chromosome—most of them unaware—putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis, say researchers at the universities of Cambridge and Exeter. ...continue reading "Extra Sex Chromosomes In Men More Common Than Many Realize"

Walking for exercise has another great health benefit - this time for the knees. A study found that frequent walking reduces frequent knee pain in people already diagnosed with knee arthritis (osteoarthritis), but not yet experiencing daily knee pain. It may also be a good way to slow damage from arthritis that occurs within the joint.

Frequent walkers reported 40% less new frequent knee pain (compared to persons who didn't walk for exercise). All the 1212 study participants were 50 years or older.

In other words, get out there and walk, preferably every day - it helps the knees!

From Science Daily: Walking Towards Healthier Knees

A new study published today in Arthritis & Rheumatology led by researchers at Baylor College of Medicine reveals that walking for exercise can reduce new frequent knee pain among people age 50 and older diagnosed with knee osteoarthritis, the most common form of arthritis. Additionally, findings from the study indicate that walking for exercise may be an effective treatment to slow the damage that occurs within the joint. ...continue reading "Walking Benefits the Knees"

Some good news for coffee drinkers - daily consumption of coffee is linked to a lower risk of acute kidney injury.

John Hopkins Medicine researchers found that daily consumption of coffee (at least 1 cup of coffee per day) lowered the risk of acute kidney injury (AKI) by 15%. But those who drank 2 to 3 cups of coffee each day had a 22% to 23% lower risk (compared to non-drinkers)

The researchers pointed out in their paper that the risk of chronic kidney disease and other diseases is also lower in daily coffee drinkers.

"Habitual coffee consumption is associated with the prevention of chronic and degenerative diseases, including type 2 diabetes, cardiovascular disease, and liver disease.

 ARIC, a large population study of 14,207 participants aged 45 to 64 years, revealed that higher self-reported daily coffee consumption was associated with a lower risk of incident chronic kidney disease after adjustments were made for demographic, clinical, and dietary factors. Thus, habitual coffee consumption has a strong potential for reducing the risk of progressive kidney disease."

From Science Daily: Coffee consumption link to reduced risk of acute kidney injury, study finds

If you need another reason to start the day drinking a cup of joe, a recent study by Johns Hopkins Medicine researchers has revealed that consuming at least one cup of coffee a day may reduce the risk of acute kidney injury (AKI) when compared to those who do not drink coffee. ...continue reading "Coffee and the Kidneys"

Liver and other organs. Credit: Wikipedia

The liver is an organ that clears the body of toxins and can actually regenerate itself if injured. A recent study found that the liver's ability to regenerate itself does not diminish with age. Good news!

A recent study analyzed livers of persons (20 to 84 years old) who had died and found that everyone's liver cells looked to be about the same age - just under 3 years old! There is constant replenishment of liver cells in the body, no matter the person's age.

There is also a subgroup of liver cells containing more DNA, that live up to a decade. But they also get replaced. Anyway you look at it - your liver is young!

From Medical Xpress: Your liver is just under three years old

The liver is an essential organ that takes care of clearing toxins in our bodies. Because it constantly deals with toxic substances, it is likely to be regularly injured. To overcome this, the liver has a unique capacity among organs to regenerate itself after damage. Because a lot of the body's ability to heal itself and regenerate decreases as we age, scientists were wondering if the liver's capacity to renew also diminishes with age. ...continue reading "No Matter Your Age, Your Liver is Young"

Something surprising - having cancer is linked to a lower risk of Alzheimer's disease and a lower risk of neurodegenerative symptoms (e.g., memory loss) during their lifetimes.

One big analysis and review of 22 studies (representing more then 9.6 million people!) calculated that cancer diagnoses are associated with 11% reduction in Alzheimer's disease occurrence. However, this relationship does not hold true for melanoma. [Also, there is a strong positive correlation between melanoma and Parkinson's disease - which is a neurodegenerative condition.]

There are some theories, but it is still unknown why this lower risk of Alzheimer's disease occurs in persons with cancer.

Excerpts from The Scientist: Cancer Tied to Reduced Risk of Alzheimer’s Disease

In recent years, scientists around the world have been probing an unexpected trend: The risk of developing cancer seems to have an inverse relationship with the risk of developing Alzheimer’s disease.  ...continue reading "Reduced Risk of Alzheimer’s Disease In Those With Cancer"

Eating berries frequently or daily has all sorts of health benefits. Two recent studies have focused on daily consumption of cranberries and found them to be beneficial for memory and neural functioning, and also for heart health.

Both studies had persons ingest whole cranberry powder (equivalent to 100 grams or 1 cup of whole cranberries) daily for 12 weeks (memory study) or 1 month (heart study).

While studies usually focus on just one type of berry to try to figure out how and what health benefits are occurring, there is no one berry a person should eat. Eat them all! Studies show they all offer something a little different, and all also have lots of fiber (very important for health!).

Also, eat real foods, not supplements. Again: studies do not find that there is one food or supplement that will prevent health problems or dementia. Eat more fruits, berries, vegetables, and cut back on ultra-processed foods. [See Medscape article below.]

From Medscape: A Cup of Cranberries a Day Tied to Better Memory

For healthy middle-aged and older adults, adding cranberries to the diet may help improve memory and brain function, in addition to lowering LDL cholesterol, new research suggests. ...continue reading "Good Reasons to Eat Cranberries"