Skip to content

Published on Leave a comment on Common Weed Killer Linked to Preterm Births

The evidence of harmful health effects from glyphosate is adding up. It's the most commonly used herbicide (weed killer) in the world, with nearly 300 million pounds of the pesticide (found in Roundup) applied each year in the United States! A recent study found that glyphosate is linked to preterm births in humans.

High levels of glyphosate and the glyphosate break-down product AMPA during late pregnancy (as measured in urine) are associated with preterm birth, according to recent research. This may be playing a role in why the United States has some of the highest rates of preterm birth rates among developed countries.

The study was conducted in Puerto Rico, where it is thought the high levels of environmental contamination (especially pesticides) plays a role in the especially high rates of preterm births (11.5%). Another study conducted in the United States (in rural Indiana with its high levels of glyphosate use on corn and soybean farms) also found shortened length of pregnancies.

Humans are exposed to glyphosate and glyphosate residues all sorts of ways, including in the foods we eat, soil, air, and water. Glyphosate is used not only as a weed-killer, but also applied to glyphosate resistant genetically engineered (GE) crops such as soy, canola, corn, and also right before harvest (preharvest) on many grain crops.

Besides preterm birth, glyphosate is linked to a number of other health problems (e.g. cancer, endocrine disruption). Studies also link glyphosate to disruptions of the human gut microbiome, with a recent study finding that glyphosate kills some key beneficial gut microbes.

Bottom line: Eat as many organic foods as possible, especially when pregnant. This is because organic farmers are not allowed to use glyphosate.

From Futurity: Team Links Popular Weed killer Chemical to Preterm Births

Exposure to a chemical found in the weed killer Roundup and other glyphosate-based herbicides is significantly associated with preterm births, according to a new study. ...continue reading "Common Weed Killer Linked to Preterm Births"

2

Published on 2 Comments on Microbes Live In Our Sinuses
Oral microbes Credit: Wikipedia

We all have millions of microbes living in our sinuses – bacteria, viruses, and fungi. This is normal.

An amazing fact is that living together are beneficial, benign, and what we normally consider harmful microbes. And this is normal. This rich and diverse community of microbes living in the sinuses is called the sinus microbiome or microbiota.

OUR SINUSES: We have 4 pairs of sinuses in our heads, which are air-filled and lined with a mucus membrane with cilia. The cilia steadily beat (700 to 800 times a minute!) in order to move mucous into the nasal cavity. Microbes live in the mucous lining.

For years it was thought that the sinuses were sterile, and a sinus infection meant that a harmful microbe (pathogen) had invaded. In the 1990s a popular view was that fungi were the cause of chronic sinusitis. But with the development of new technologies (genetic sequencing) in the last 2 decades, it was discovered that millions of all sorts of microbes live in the sinuses in both healthy and sick persons. And yes, that it was normal to have fungi in the sinuses (so that theory was dropped).

THE CURRENT VIEW: Millions of microbes live in complex communities, interact with one another, and with us (we’re their host!). In healthy persons all the microbial species are in equilibrium, and potentially harmful species are kept in check. But sometimes the communities can become disrupted and imbalanced – this is called dysbiosis.

When there is disruption (e.g., from an infection, allergies), then there can be an overgrowth or a big increase in the potentially harmful microbes living in the sinuses. This can make you more susceptible to an infection or it can result in sinusitis symptoms. (In chronic sinusitis there is an imbalanced sinus microbiome and also inflammation of the sinus mucous lining.)

Staphylococcus Credit: Wikipedia

A HEALTHY SINUS MICROBIOME: It turns out that what is a healthy sinus microbiome varies from person to person. Yes, there is a “core” sinus microbiome of species that are shared throughout the world. (For example: Corynebacterium and Staphylococcus species)

Everyone’s sinus microbiome is unique – you may have more of some species, less or none of others. Generally a heathy sinus microbiome has more richness of species and diversity, which is diminished in people with chronic sinusitis.

But guess what? Even if a person has fewer or more species – the total number of bacteria present is the same. Think of it this way – if there is an empty space, microbes will move in to occupy it.

A big surprise in the last 2 decades is that healthy sinuses have low levels of harmful microbes (e.g.  Staphylococcus aureus) coexisting with beneficial microbes. They are considered to be “opportunistic pathogens”, which means they can become harmful if the conditions are right. For example, if the sinus microbial community becomes disrupted by an infection. Which is why so many people develop sinusitis after a cold or other respiratory infection.

Most research has looked at the multitudes of bacterial species living in our sinuses. But there are also species of viruses and fungi, and much is still unknown about them. The viruses (our “virome”) can be a stable part of our microbial community or only there briefly. Healthy persons (and those with sinusitis) also have fungi living in the sinuses.

In addition, some people have archaea living in their sinuses – one-celled organisms that don’t have a cell nucleus. A minority of people have archaea in their sinuses, but it is unknown why they are there, what is their role (if any), and why only some people have them. They can also be found in the human gut.

It turns out that we all (both healthy and sick) have biofilms living on the mucus lining of the sinuses. However, research suggests that they may be a little different in healthy persons – they are smaller (microcolonies), don’t cause an inflammatory response, and are kept in check by the other microbes. (Biofilms are bacteria communities sticking to one another, and with a protective slime coating.)

Some microbes have an important role in the health of the sinus microbiome, even if they are there only in tiny amounts – these are keystone bacteria. Lactobacillus sakei is one of them (in Lanto Sinus), and research shows it s depleted in persons with chronic sinusitis.

What else influences the species of microbes in the sinus microbiome? The list includes illnesses, allergies, asthma, cigarette smoking, age of the person, antibiotics, and whether sinus surgery has been done. All these factors help explain why in both health and sickness, every person’s sinus microbiome is unique.

Bottom line: We have trillions of microbes living in our bodies, and this includes the sinus microbiome. Bacteria, viruses, fungi, and for some people also archaea. The field is still in its infancy and so we still have much to learn.

Published on Leave a comment on The Amazing Rachel Carson

Today is Rachel Carson's birthday! Rachel Carson (May 27, 1904 - April 14, 1964) was an extraordinary and courageous person, who is best known for exposing the harms of long-lasting pesticides. She was a marine biologist and author, who published several best-selling books about the environment.

Rachel Carson discussed health and environmental harms that synthetic pesticides, especially DDT, were causing to wildlife and our environment in the widely read book Silent Spring (published in 1962). Chemical companies fiercely opposed the book, but it spurred the American people to finally take action on pesticides. It led to a nationwide ban on DDT and other long-lasting pesticides, as well as helping inspire a grassroots environmental movement that led to the creation of the United States Environmental Protection Agency (EPA).

After her death, President Jimmy Carter awarded her the Presidential Medal of Freedom. (More about Rachel Carson) To this day, the book Silent Spring is considered an environmental classic, and one of the most significant publications of the last century.

One tribute to her work is the Silent Spring Institute, a national environmental health research organization dedicated to uncovering the links between chemicals in our everyday environment and women's health. Another focus is on breast cancer prevention (by lowering exposure to harmful chemicals, as well as encouraging companies to develop safer products). (Yes, Rachel Carson died of breast cancer.)

Some quotes from Rachel Carson. They still apply decades later:

"A Who's Who of pesticides is therefore of concern to us all. If we are going to live so intimately with these chemicals eating and drinking them, taking them into the very marrow of our bones - we had better know something about their nature and their power.”

"It is also an era dominated by industry, in which the right to make a dollar at whatever cost is seldom challenged."

"These sprays, dusts, and aerosols are now applied almost universally to farms, gardens, forests, and homes - nonselective chemicals that have the power to kill every insect, the 'good' and the 'bad,' to still the song of birds and the leaping of fish in the streams, to coat the leaves with a deadly film, and to linger on in soil-all this though the intended target may be only a few weeds or insects. Can anyone believe it is possible to lay down such a barrage of poisons on the surface of the earth without making it unfit for all life? They should not be called 'insecticides,' but 'biocides.' (Silent Spring, 1962)

Published on Leave a comment on Pregnancy and Air Pollution Linked to Asthma in the Children

It has long been known that children living in congested cities have higher rates of asthma. All those vehicles, all that pollution. A recent study found that prenatal air pollution exposure is also important in asthma development.

Pregnant women exposed to high levels of tiny ultra-fine particles (UFPs, <0.1 µm) in the air were more likely to have children who developed asthma in the preschool years. Both boys and girls were affected, but high levels seemed to be especially harmful for girl babies exposed late in pregnancy.

Many of the women lived near major roadways with high traffic density - exposure to ultra-fine particles is greater there.

Ultra-fine particles are so small (<0.1 µm) that they can be considered nanoparticles. Their small size makes them so harmful - they can enter the lungs easily and from there travel throughout the body (including the organs), where they cause inflammation and other health effects. Unfortunately, ultra-fine particles are not regulated or routinely monitored in the United States.

From Science Daily: In utero exposure to tiny air pollution particles is linked to asthma in preschoolers

Women who were highly exposed to ultra-fine particles in air pollution during their pregnancy were more likely to have children who developed asthma, according to a study published in the American Journal of Respiratory and Critical Care Medicine in May. ...continue reading "Pregnancy and Air Pollution Linked to Asthma in the Children"

Published on Leave a comment on Endangered Species Day

Today is Endangered Species Day! It is a day to think about the beauty (and fragility) of life. Support efforts to protect and save endangered species and their habitats!

Back in 1966 Congress passed the Endangered Species Preservation Act, and then in 1973 a more comprehensive law - the Endangered Species Act. The purpose is to protect and recover imperiled species, and to preserve the ecosystems upon which these species depend. Under the act, species may be listed as either endangered or threatened.

There are over 1600 species of plants and animals currently listed as either threatened or endangered in the United States. We (humans) are the main reason for species being threatened, endangered, or becoming extinct in the United States.

Some ways humans have contributed to this: killed off the species (e.g. passenger pigeons killed for sport, dodo bird), pesticides (DDT made bird shells too weak, and many pesticides kill off pollinator species), loss of habitat (e.g. from development or polluting of habitat), and introducing nonnative or invasive species. [See EPA comments] And then there is climate change which is altering ecosystems... also caused by humans.

Some things you can do: 1) reduce pesticide use in your yard and garden (to save pollinators, beneficial insects, birds), 2) don't litter, 3) reduce use of plastics (plastic winds up in animals, birds, fish), 4) oppose development that destroys critical habitat, 5) support conservation efforts, and 6) support groups that work on the issue of endangered species. 7) You can even create a backyard wildlife habitat!

Published on Leave a comment on Eating Sardines Linked to Lower Diabetes Risk

It has long been known that eating oily fish (e.g. salmon, sardines) has health benefits for the heart. But it also looks like regularly eating sardines may be a good way to lower the risk of getting type 2 diabetes, as well as improving heart health.

In a study (conducted in Spain) 152 persons at risk for developing type 2 diabetes ("pre-diabetes") were randomly assigned to one of 2 groups for 1 year: Group 1 regularly ate sardines +  followed a diabetes preventive diet, or Group 2 ate the same diabetes preventive diet, but without sardines. All participants were 65 years or older.

They found that after 1 year, the sardine group had greater health improvements than the non-sardine group. Fewer in the sardine group were still in the prediabetes group, and fewer had developed type 2 diabetes. The sardine group also had decreased triglycerides (good), greater increases in healthy HDL cholesterol, reduced insulin resistance, and lower blood pressure, as compared to the non-sardine group.

The sardine group also had higher taurine levels in the blood, as well as increases in nutrients linked to health benefits, including omega-3 EPA and DHA, vitamin D, and fluorine. Taurine has antioxidant and anti-inflammatory benefits.

What was their weekly consumption of sardines? They consumed 200 g of canned sardines in olive oil per week - eaten as 100 g servings twice per week. Which is a little less than eating two of the little 125 g cans of sardines in olive oil available at the grocery store. It was recommended that they eat the entire sardine, including bones, due to their rich content of calcium and vitamin D. [By the way, while the researchers don't discuss this - increased extra virgin olive oil consumption also has health benefits.]

Medscape article: Sardines Linked to Reduced Type 2 Diabetes Risk

Excerpts from Medical Xpress: Eating sardines regularly helps prevent type 2 diabetes

The health benefits of sardines and oily fish are widely known: their high levels of unsaturated fats help to regulate cholesterol levels and prevent the onset of cardiovascular diseases. However, the benefits don't end there.  ...continue reading "Eating Sardines Linked to Lower Diabetes Risk"

Published on Leave a comment on Glyphosate May Be Having a Harmful Effect On Our Gut Microbiome

Uh oh... Glyphosate is the most widely used herbicide (plant-killer) in the world, and its pervasive use may be harming our gut microbiomes. Glyphosate (which is in Roundup) is used not only as a weed-killer, but also applied to glyphosate resistant genetically engineered (GE) crops such as soy, canola, corn, and also right before harvest (preharvest) on many grain crops. Thus we find glyphosate and glyphosate residues all around us, including in the foods we eat.

Researchers at the University of Turku  in Finland developed a bioinformatics tool to examine glyphosate effects on gut bacteria. They found that glyphosate kills many bacterial species found in the human gut, including such important keystone bacteria as Faecalibacterium prausnitzii. Their words: "54% of species in the core gut microbiome are sensitive to glyphosate". (A nice way of saying it kills them.) They summarize:

"A large proportion of bacteria in the gut microbiome (Qin et al., 2010) are susceptible to glyphosate (class I); thus, the intake of glyphosate may severely affect the composition of the human gut microbiome. "

Glyphosate has already been linked to a number of health problems (e.g. cancer, endocrine disruption). The gut microbiome or microbiota is the millions of microbes living in our intestines, and they are very important to our health. Imbalance or disruptions to our gut microbiome result in inflammation, chronic conditions, and diseases.

What to do? Try to eat as many organic foods, especially grains, soy, and corn, as possible. Organic farmers are not allowed to use glyphosate. Try to avoid using glyphosate-based herbicides on your property.  Unfortunately, our government agencies are not protecting us with regards to glyphosate, and the US allows higher glyphosate residues in food than in the European Union.

From Science Daily: Glyphosate may affect human gut microbiota

Glyphosate is the most commonly used broad-spectrum herbicide. Researchers from the University of Turku in Finland have developed a new bioinformatics tool to predict if a microbe, e.g. a human gut bacterium, is sensitive to glyphosate.  ...continue reading "Glyphosate May Be Having a Harmful Effect On Our Gut Microbiome"

Published on Leave a comment on Low Iodine Levels During Pregnancy Poses Risk to the Baby

Iodine is an essential mineral for health, especially during pregnancy, because it is needed for intellectual development and thyroid functioning. For years people bought iodized table salt at the grocery store in order to make sure that they have enough iodine in the diet. However, the use of other salts (e.g. Himalayan salt) that don't have added iodine, and following a vegan or vegetarian diet can increase the risk of iodine deficiency.

A small study by Australian researchers looked at iodine levels in 2 groups of pregnant women, who were either vegan/plant-based diet participants or omnivores (eating both meat and plants). Both groups had urine with iodine levels below the World Health Organization recommended 100 µg per liter, but the vegan/plant-based group was far lower at 44 µg per liter. Those eating Himalayan salt had severely deficient levels: 23 µg per liter. The study did not look at the intellectual functioning of the infants after they were born.

How to get enough iodine in the diet? Foods containing iodine are seafood, seaweed, bread fortified with iodine, iodized salt, eggs, and dairy foods. Also, iodine supplements. Research indicates that adequate iodine intake before conception is necessary to ensure optimal maternal thyroid function during pregnancy, which is required for fetal intellectual development.

Medical Xpress: Poor iodine levels in pregnancy poses risks to fetal intellectual development

A growing number of young Australian women are at increased risk of having children born with impaired neurological conditions, due to poor iodine intake.  ...continue reading "Low Iodine Levels During Pregnancy Poses Risk to the Baby"

Published on Leave a comment on Organic Meat Less Likely To Be Contaminated By Harmful Bacteria

Well, the following findings make total sense. A recent study found that organic meat (beef, pork, chicken, turkey) is less likely to be contaminated by harmful bacteria, including multidrug resistant bacteria. These findings hold even if it is processed in a place that also processes non-organic (conventional) meat. But the best results are if organic meat is processed at a processing facility that only handles organic meat.

One interesting finding was that the type of meat processing facility also mattered. Conventional meat that is processed by a "split-processing" facility (processes both organic and conventional meat) had lower rates of multidrug resistant bacteria contamination than processing facilities that only handle conventional meat. This could be because disinfection has to take place in-between processing of organic and conventional meat batches.

This antibiotic use and resistant bacteria association has been known for years for both humans and animals. If antibiotics and other antimicrobials are avoided whenever possible, then bacteria are less likely to mutate, and there is a lower incidence of multidrug resistant microbes.

Bottom line: try to eat organically grown meat whenever possible. It's better environmentally and better for health.

From Science Daily: Organic meat less likely to be contaminated with multidrug-resistant bacteria

Meat that is certified organic by the U.S. Department of Agriculture is less likely to be contaminated with bacteria that can sicken people, including dangerous, multidrug-resistant organisms, compared to conventionally produced meat, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.  ...continue reading "Organic Meat Less Likely To Be Contaminated By Harmful Bacteria"

Published on Leave a comment on Archaea May Be Living In Your Sinuses

Everyone has millions of microbes living in complex communities in their sinuses. All these hundreds of species of bacteria, fungi, and viruses are the sinus microbiome or sinus microbiota. In addition, some (many?) people also have tiny organisms called archaea living in their sinuses.

What are archaea? Archaea are single-celled organisms that lack cell nuclei, and have a unique cell wall membrane. Very little is known about them, what their role is in the sinuses (that is, what are they doing there?), how do they interact with the host (the person), and whether their presence is beneficial or not.

There are only a few studies looking at archaea in humans, and while very little is known, the current view is that there are no known harmful archaea ("archaeal pathogens or parasites").

In a 2019 study, French researchers found archaea in the sinuses of 9 of their patients with chronic sinusitis - and therefore thought they were linked to disease. But unfortunately they didn't look to see if archaea are also found in the sinuses of healthy persons, thus there wasn't a comparison group. They found methanogenic archaea (the only microorganisms able to produce methane) in these nine patients, and they thought that the archaea were contributing to or causing the chronic sinusitis.

The Methanobrevibacter species they found were  M. smithii, M. oralis, and M. massiliense, of which 2 have been found in dental plaque and periodontitis lesions, and one is a gut methanogen. [Note: This means it is found in the gut and is methane producing - but that doesn't mean it is harmful.]

Finally, a more recent and comprehensive study looked at archaea and bacteria in the sinuses of both healthy persons and those with chronic sinusitis. University of Auckland researchers found that only 6 out of 70 persons (both healthy and with sinusitis) had archaea in the sinuses, and they were very low in numbers and in diversity. In those with archaea, there was a lot of variation between people. They did not see any archaea associated with chronic sinusitis.

Archaea found were from Euryarchaeota, Thaumarchaeota, and Methanobrevibacteriaceae phyla.

One can only wonder what the archaea are doing in the sinuses in those with them. Especially, as the researchers point out that archaea are characterized by a unique cell wall membrane that "assists survival in extreme conditions such as hydrothermal vents, salt lakes, anoxic and highly acidic or alkaline environments". Also, that recent studies suggest that the human immune system recognizes and can be "activated" by archaea.

Archaea. Credit: Wikipedia

Finally, studies also mention that archaea are resistant to many antibiotics (because of lack of peptidoglycan in their cell wall). It is unknown how this influences their role (if any) in human health and disease.

As you can see, much is unknown right now. Even how many people have archaea in their sinuses, and what kinds of archaea. Stay tuned.

Article by B.W. Mackenzie et al in Frontiers in Cellular Infection and Microbiology: A Novel Description of the Human Sinus Archaeome During Health and Chronic Rhinosinusitis