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Published on Leave a comment on COVID-19 During Pregnancy

Worrisome news: having a COVID-19 infection during pregnancy may be injuring the placenta, even if the pregnant woman has no symptoms (asymptomatic) and the baby appears healthy at birth. The human placenta is the temporary organ that nourishes and maintains the developing fetus during pregnancy. It provides oxygen and nutrients to the baby, and removes waste products.

A small study by doctors at the Feinberg School of Medicine (Chicago, Illinois) examined 16 placentas after babies were born - 15 in the third trimester (all live, healthy babies), 1 in the second trimester (after the fetus died). The placentas of women who were currently infected with COVID-19 or had it earlier in the pregnancy showed abnormal or injured blood vessels, which can result in insufficient blood flow between the mother and developing baby. Two common types of injuries were abnormal blood vessels (maternal vascular malperfusion) and blood clots in the placenta (intervillous thrombi).

The study authors said that pregnant women should therefore be monitored more carefully, perhaps with non-stress tests (to see how well the placenta is delivering oxygen) or ultrasounds to measure growth. The good news is that currently the evidence does not suggest that pregnant women have more severe COVID-19 infections than non-pregnant women.

Also good news is that the 15 babies born in the third trimester appeared healthy and normal weight (only one was pre-term, but healthy), and that at birth all the babies were negative for COVID-19. Thus, they did not get the infection from their mothers during pregnancy.

Excerpts from Science Daily: Placentas from COVID-19-positive pregnant women show injury

The placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth, reports a new Northwestern Medicine study.   ...continue reading "COVID-19 During Pregnancy"

Published on Leave a comment on Dairy Products, Hypertension, Diabetes, and Metabolic Syndrome

For several years I've noticed studies that show beneficial health effects from consumption of dairy products, especially whole milk or full-fat products, and also fermented dairy products (e.g. yogurt, cheese). A recent international study (21 countries on 5 continents) found similar results: higher intake of dairy foods, especially full-fat dairy, is associated with lower incidence of type 2 diabetes, high blood pressure (hypertension), and metabolic syndrome.

Metabolic syndrome is a group of conditions that increases the risk of heart disease, stroke, type 2 diabetes, and early death. Risk factors include increased blood pressure, excess body fat around the waist, elevated triglycerides and cholesterol levels, and elevated blood glucose.  Diet plays a role in whether one develops metabolic syndrome and diabetes. [Being overweight and being inactive are also important risk factors.]

What was the higher intake of dairy products that was associated with health benefits? At least 2 servings per day. The study did not look into what kind of dairy people drank and ate - whether cow, sheep, camel, or goat milk dairy. The assumption is: dairy is dairy!

While it was an observational study, it was significant, especially because the 131,481 participants (aged 35 to 70 years) were from world regions not typically studied in dairy consumption studies. They were tracked for about 9 years.

Excerpts from Science Daily: Dairy-rich diet linked to lower risks of diabetes and high blood pressure

Eating at least two daily servings of dairy is linked to lower risks of diabetes and high blood pressure, as well as the cluster of factors that heighten cardiovascular disease risk (metabolic syndrome), finds a large international study published online in BMJ Open Diabetes Research & Care.  ...continue reading "Dairy Products, Hypertension, Diabetes, and Metabolic Syndrome"

Published on Leave a comment on Should Ripe Tomatoes Be Refrigerated Or Kept At Room Temperature?

Can tomatoes be refrigerated or does that destroy their taste? This seems to be a pressing issue that is much discussed while people are at home during the pandemic. The advice I generally see is to NOT refrigerate them - to leave them out at room temperature until they are eaten.

Well... a German study examined that particular question and according to the researchers - the taste of the tomatoes is the same whether refrigerated or kept at room temperature for 4 days. Instead, the variety of tomato is most important for the flavor (taste).

Of course! Every variety of tomato has a different taste. One thing I question is the refrigerator temperature of 44.6°F (7°C) that was used, which seems a bit warm. Refrigerators in the US are normally kept cooler, between 33 and 39 degrees.

From Science Daily: Should tomatoes go in the fridge?

There is much debate about the correct storage of tomatoes. There are two main options available to consumers: storage in the refrigerator or at room temperature. A research team from the University of Göttingen has now investigated whether there are differences in the flavour of ripe tomatoes depending on how they are stored and taking into account the chain of harvesting from farm to fork. No perceptible difference was found: the variety of tomato is much more important. The results have been published in the journal Frontiers in Plant Science.  ...continue reading "Should Ripe Tomatoes Be Refrigerated Or Kept At Room Temperature?"

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Published on 1 Comment on Drinking Coffee Associated With Lower Body Fat in Women

More good news for coffee lovers. A study that looked at a large sample of adults in the US found that there is a dose-response association for daily coffee consumption and body fat (adiposity). Higher coffee intake (both regular and decaf) was associated with lower body fat in women, but not men.

The biggest effects were seen in women aged 20 to 44 years (who drank 2 to 3 cups/day), and in 45 to 69 year old women who drank 4 or more cups of coffee per day - that is, they had lower total body fat and trunk body fat when compared to those who didn't drink coffee.

Coffee has over 1000 bioactive compounds in it, such as caffeine, chlorogenic acids, and diterpenes. Recent studies found that moderate coffee intake (3 to 4 cups/day) lowers the risk of type 2 diabetes, heart disease, (early) death, lower risk of some cancers, and has a beneficial effect on metabolism (increases it) and inflammation. [Note: chronic inflammation is linked to a number of diseases, so want to lower it.]

The researchers suggest that there are compounds in coffee (other than caffeine) that regulate weight and act as "antiobesity compounds". Perhaps view drinking coffee as a healthy diet strategy for women!

Excerpts from Science Daily: Coffee linked to lower body fat in women

Women who drink two or three cups of coffee a day have been found to have lower total body and abdominal fat than those who drink less, according to a new study published in The Journal of Nutrition.  ...continue reading "Drinking Coffee Associated With Lower Body Fat in Women"

Published on Leave a comment on Certain Chemicals Linked to Celiac Disease

Worried about the effects of persistent pesticides, flame retardants, and the chemicals used in non-stick pans (e.g.Teflon) on human health? An interesting small study from researchers at New York University looked at whether there is a link between having higher levels of these chemicals and celiac disease (a digestive disorder in which there is an abnormal response to foods with gluten). And yes, they found one.

Certain pesticides, flame retardants (PBDEs), and nonstick chemicals (PFASs) are known as persistent organic pollutants (POPs). They are known to be endocrine disruptors (meaning they disrupt the hormonal system). The researchers think that because there is an interplay between endocrine and immune systems, then perhaps these chemicals may contribute to the development of celiac disease in people who are genetically susceptible to it.

Thirty children and young adults newly diagnosed with celiac disease were compared to 58 individuals without the disease.  Higher levels of these chemicals were found in the blood in those with celiac disease, when compared to those without celiac disease.

More reasons to avoid non-stick pots and pans, avoid flame retardants, avoid using pesticides on lawns, and to eat organically raised foods.

From Futurity: CELIAC DIAGNOSIS MORE LIKELY WITH HIGHER BLOOD LEVELS OF PESTICIDES

Children and young adults with high blood levels of pesticides—and with high levels of pesticide-related chemicals called dichlorodiphenyldichlorethylenes—were twice as likely to receive a new diagnosis of celiac disease than those without high levels, report researchers.  ...continue reading "Certain Chemicals Linked to Celiac Disease"

Published on Leave a comment on The Foods We Eat and Breast Cancer

Once again, a study found that the foods we eat are associated with our risk for breast cancer. Results from a long-running European study found that certain foods (alcohol, wine, beer) are associated with an increased risk of breast cancer, while other foods (foods high in fiber, certain fruits such as apples and pears, and higher carbohydrate intake) are associated with a lower risk of breast cancer.

This study used data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which enrolled 272,098 women (between 1992 and 2000) from 10 European countries. Women filled out an extensive nutritional questionnaire (to assess intake of 92 foods and nutrients) at the beginning, and then they were followed for about 15 years.

It has long been known that higher alcohol intake raises breast cancer risk, especially risk of postmenopausal breast cancer, and this study supports that. Fruits (esp. apples and pears) were associated with a lower risk of breast cancer - and they were also a main source of fiber foods, as well as carbohydrates.

What was not discussed in the study was that along with having many nutrients and high amounts of fiber, produce also contains multitudes of microbes. A recent study found that one apple alone has millions of bacteria! When we eat fresh fruits and vegetables, we are introducing microbes into the gut, as well as feeding beneficial gut microbes (and ultimately lowering chronic inflammation).

Unfortunately they only asked the women about foods one time at the beginning of the study. The women could have changed their dietary patterns over the next 15 years, especially since so many new foods have become popular and widely available. Also, looking at the food list - there was no mention of olive oil, which researchers view as anti-inflammatory, and lowering the risk of breast cancer.

Study by A.K.Heath et al. (in Breast Cancer Research). Excerpts from Medscape: Nutrient-Wide Association Study of 92 Foods and Nutrients and Breast Cancer Risk

Six foods and nutrients were identified as associated with risk of breast cancer in the EPIC study (10,979 cases). Higher intake of alcohol overall was associated with a higher risk of breast cancer, as was beer/cider intake and wine intake, whereas higher intakes of fiber, apple/pear, and carbohydrates were associated with a lower risk of breast cancer.   ...continue reading "The Foods We Eat and Breast Cancer"

Published on Leave a comment on Successful Treatment for Crohn’s Disease?

The number of people who have Crohn's disease has been rising steadily over the years. Crohn's disease is a debilitating intestinal bowel disease (IBD) which causes severe abdominal pain, diarrhea, weight loss, and fatigue. A number of studies have focused on gut bacteria in those with Crohn's disease and found dysbiosis (microbial community out of whack), but there is disagreement over the cause of Crohn's and the dysbiosis.

Up to this point no treatments (drugs, surgery, diet, etc.) have had long-term success, and so patients have to take medications throughout life. This is why a small study (10 patients) finding long-term remissions (3 to 23 years) with medicines no longer required is exciting.

According to the Australian researchers success was achieved by having the individuals take a variety of antibiotics over a long period (about 3 years!), and for some also a fecal microbiota transplant (FMT) in the form of a "crap" or "poop" pill  (freeze-dried donor fecal microbiota).

The researchers felt that Crohn's disease is caused by an infection, perhaps  Mycobacterium avium subsp. paratuberculosis (MAP), and they chose courses of various antibiotics that they thought would work against MAP.

Symptoms of Crohn's disease totally cleared up, intestines (including fistulas) healed, and patients discontinued all medications and treatments. The authors called it a "prolonged remission" in the study. But they did point out that this group was special, and that others treated that same way also achieved remission, but were unable to totally go off all medications.

So we'll see. It needs to be duplicated in more people first.

Excerpts from Medical Xpress: Study: Antibiotic and 'crapsule' therapy eliminate need for further treatment of Crohn's disease

The Centre for Digestive Disease (CDD) headed by Professor Thomas Borody has cured Crohn's disease as reported today by Dr. Gaurav Agrawal in Gut Pathogens.  ...continue reading "Successful Treatment for Crohn’s Disease?"

Published on Leave a comment on Drinking Filtered Coffee Is Healthier Than Unfiltered Coffee

The Scandinavians really love to drink coffee, and of course researchers study the health effects of all that coffee drinking. Two recent studies both found health benefits from drinking filtered coffee (such as drip coffee), but not unfiltered coffee.

A study conducted in Norway found that over a 20 year period drinking filtered coffee daily was associated with lower death rates, when compared to those who did not drink coffee or drank unfiltered coffee. The best health effects (lowest mortality rate) were associated with drinking 1 to 4 cups per day of filtered coffee, and the unhealthiest (highest mortality rate) was drinking 9 or more cups per day of unfiltered coffee.

The researchers thought that unfiltered coffee raised the cholesterol levels, because of the lipid-raising components of coffee - the diterpenes kahweol and cafestol, which are filtered out by coffee filters. This could explain the association between unfiltered coffee and higher death rates from heart disease. Other studies have found that higher consumption of filtered coffee results in lower levels of markers of inflammation.

As was discussed in an earlier post, a recent study from Sweden found that drinking 2 to 3 cups of drip coffee (using a filter) daily lowers the risk of type 2 diabetes, while drinking boiled coffee has no health effect. The researchers put it nicely, that habitually drinking filtered coffee has a "protective role" on type 2 diabetes development.

On the other hand, other popular ways of preparing coffee don't use filters - French press, espresso, percolator, and coffee pods, and so may have similar not-so-great health effects to boiled coffee. But still unknown at this time - studies are needed.

From Science Daily: How to make the healthiest coffee

Today scientists announce the healthiest way to make a brew.  ...continue reading "Drinking Filtered Coffee Is Healthier Than Unfiltered Coffee"

Published on Leave a comment on Rising Carbon Dioxide Levels May Harm Our Thought Processes

The possibility that rising carbon dioxide levels could eventually result in harmful effects on people's thinking (cognition) is scary. Currently levels are above 400 ppm and rising steadily each year. The Intergovernmental Panel on Climate Change predicts that outdoor CO2 levels could climb to 930 ppm by 2100, which means urban and indoor levels would be even higher.

Studies suggest that at high levels of carbon dioxide our thinking gets worse. A University of Colorado study reports that a growing body of evidence finds that as CO2 levels increase, there are effects on thinking (cognitive functioning), including decision making, planning, and complex strategic thinking. As carbon dioxide levels rise to 945 ppm and higher, the effects are even more significant, especially with mentally demanding tasks.

Think of the air in stuffy conference rooms or offices, which studies show has a negative effect on different aspects of our thought processes. The stuffy air is from higher levels of CO2. What if in the future this is our regular "fresh air", with no possibility of escape? The best case scenario is that we do not allow carbon dioxide levels to get that high by reducing fossil fuel emissions. Starting now.

From Science Daily: Rising carbon dioxide causes more than a climate crisis -- it may directly harm our ability to think

As the 21st century progresses, rising atmospheric carbon dioxide (CO2) concentrations will cause urban and indoor levels of the gas to increase, and that may significantly reduce our basic decision-making ability and complex strategic thinking, according to a new CU Boulder-led study. By the end of the century, people could be exposed to indoor CO2 levels up to 1400 parts per million -- more than three times today's outdoor levels, and well beyond what humans have ever experienced.  ...continue reading "Rising Carbon Dioxide Levels May Harm Our Thought Processes"

Published on Leave a comment on Fiftieth Anniversary of Earth Day

Today is the fiftieth anniversary of Earth Day!

The very first Earth Day was a nationwide rally held back in April 22, 1970 to raise awareness of threats to the environment. Later that year the Environmental Protection Agency (EPA) was established, and soon after that important environmental laws were passed, such as the Clean Air Act, the Clean Water Act, and the Endangered Species Act.

And here we are 50 years later. With many environmental laws being dismantled. The crisis of climate change. And the coronavirus COVID-19 pandemic.

This is our earth. Our only earth. Let's treasure it and take care of it.