The microbes living on and in us (the human microbiome or microbiota) play a big role in our health. Certain microbes are even implicated in cancer development and progression. Thus, it shouldn't come as a surprise that new research finds that certain bacteria are linked with bladder cancer.
It has long been known that certain nitrosamine compounds, which are in tobacco smoke, can induce bladder cancer - both in humans and rodents (e.g., mice). Nitrosamines are carcinogenic (cancer causing).
The study was done with mice given nitrosamine compounds (in their drinking water) for 12 weeks. The interesting part was that if antibiotics were given at the same time to the mice, bladder cancer did not develop in most of those mice. But it did develop in most of the mice not given antibiotics.
Since antibiotics reduce the number of bacteria in the gut, this means that gut microbes play a part in the bladder tumor onset. The researchers did find 12 bacterial species that they thought played a role in the mice, but it is unknown whether the same or different species play a role in human bladder cancer onset.
Will the use of antibiotics prevent bladder cancer also in humans? Stay tuned..
From Medical Xpress: Gut microbes implicated in bladder cancer
At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world. This includes—as shown in a new study by EMBL researchers and collaborators at the University of Split, Croatia—the way the body responds to carcinogens and develops cancer. ...continue reading "Tobacco Smoke, Bladder Cancer, and the Gut Microbiome"