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Mediterranean diet Credit: Wikipedia

People have been arguing for years over what kinds of foods and dietary patterns are best for health, with many studies finding that a Mediterranean style diet is best for health.  Another recent study found that a Mediterranean-style diet rich in fruits, vegetables, nuts, legumes, whole grains, fish, and dairy is best for heart health when compared to other diets.

The study of 3042 Greek adults found that those following a plant-based style diet (basically a Mediterranean-style diet) had a 26% lower risk of developing heart disease over a 20 year period, when compared to either a Western diet rich in processed meat and ultra-processed foods, or to a high-calorie, but low-white-meat dietary pattern.

The high calorie, low white-meat diet seemed especially unhealthy. They also found that physical activity reduced heart disease (cardiovascular disease) risk, but smoking increased it.

Physical activity reduced CVD risk, while smoking increased it.

Excerpts from Medical News: Plant-based Mediterranean-style diet cuts heart disease risk by 26%

A recent European Journal of Nutrition study examined common dietary patterns in a Mediterranean cohort and assessed their long-term associations with cardiovascular disease (CVD) risk and outcomes. 

Poor dietary habits, especially inadequate consumption of nutrient-dense foods, remain a leading modifiable risk factor. ...continue reading "A Mediterranean Style Diet Cuts the Risk of Developing Heart Disease"

Human eye Credit: Wikipedia

A recent large study found that vitamin B3 (nicotinamide) supplements may help in preventing glaucoma (specifically primary open-angle glaucoma) and also need fewer treatments (e.g., eye drops and laser procedures) in those with glaucoma.

Glaucoma refers to many diseases involving eye pressure increases and damage to the optic nerve, which can result in permanent vision loss and blindness. Primary open-angle glaucoma (POAG) is the most common form of glaucoma. The study found that those taking nicotinamide supplements had a 66% lower risk of developing glaucoma.

Since the study is behind a paywall, I've included summaries (each a little different) from 2 web-sites describing the study.

From Medical Xpress: Could vitamin B3 prevent silent thief from stealing vision? New study finds protective effects against glaucoma

Often called the silent thief of sight, glaucoma is a group of eye diseases that gradually damage the optic nerve, often without warning signs. It is linked to increased pressure (ocular hypertension) inside the eye and, if left untreated, can lead to permanent vision loss. Even with ongoing treatment, some people still face the risk of progressive vision loss.

This led scientists to look for newer therapeutics that can help manage the disease's progression, such as nicotinamide, a form of vitamin B3. ...continue reading "Study Finds Vitamin B3 Supplements Lower the Risk of Developing Glaucoma"

Hypertension (high blood pressure) is a big problem in adults. A large European study found that eight preservative food additives are associated with high blood pressure and heart (cardiovascular) disease. And the more a person eats additives in their daily diet (meaning more ultra-processed foods), the greater the risk of developing hypertension and heart disease.

The most problematic of the preservative food additives in this European study included: potassium sorbate, potassium metabisulphate, sodium nitrite, ascorbic acid, sodium ascorbate, sodium erythorbate, citric acid, extracts of rosemary. These results suggest that a higher intake of preservative food additives means a greater intake of ultra-processed food, which ultimately is not good for the health (increased risk of high blood pressure and heart disease).

Note that in the list of US problematic food additives may be somewhat different, because different additives may be more common. But all are indications of ultra-processed foods.

Bottom line: Nutrition matters! Eat as many minimally processed foods as possible. Also, read ingredient labels and try to avoid products that contain ingredients that are not normally found in a kitchen (e.g., xanthan gum, carrageenan).

From Science Daily: Researchers found 8 common food additives linked to high blood pressure and heart disease

A massive study suggests that some common food preservatives may be putting heart health at risk. ...continue reading "Food Additives and Hypertension"

We all know that vitamin C is important for our health, especially skin health, but it is also important for a healthy brain. A recent study found higher levels of vitamin C in aging adults is linked to a healthier aging brain. Nutrition matters!

The study found that having low levels of vitamin C in blood plasma in aging adults is correlated with having lower brain gray matter volume and connectivity. The study looked at 2040 aging adults (median age 69 years) in Japan - using both MRI scans and blood plasma samples.

As we age, the volume of the brain shrinks - this is normal. There are both structural and connectivity changes - again, it's normal.  But...you want to delay and minimize these changes, which is why this research finding that vitamin C is important for aging brain health is significant. As the researchers point out, one can make nutritional changes by increasing vitamin C foods in the diet. (BTW, generally foods are superior to supplements.)

Gray matter of the brain is where processing information, movement, and emotion control occur. It has an effect on new memories and multitasking.

Other studies have also pointed out that vitamin C are important for aging brain health. Lower levels of vitamin C have been associated with a higher risk of dementia and other neurodegenerative diseases.

Bottom line: Try to eat foods high in vitamin C frequently, preferably daily.

From  Science Daily: Scientists discover a surprising link between vitamin C and brain health

Researchers have found another clue that diet may influence how the brain ages. In a study of more than 2,000 older adults in Japan, people with lower levels of vitamin C in their blood tended to have less gray matter and weaker connections within an important brain network involved in memory and attention. While the findings do not prove that vitamin C protects the brain, they strengthen evidence that good nutrition could play a role in maintaining cognitive health later in life. ...continue reading "Vitamin C Is Important For Aging Brain Health"

Uh-oh, two popular supplements don't have the health benefits that many think. Millions take vitamin D or calcium (or both) for stronger bones. A large review of 69 studies found that taking calcium or vitamin D or both does not prevent fractures and falls in older adults.

Other studies have had similar results. Bottom line: Focus on eating well and getting enough exercise, especially resistance exercises and balance exercises.

From Science Daily: Millions take calcium and vitamin D for stronger bones. A major review finds little benefit

A comprehensive review published in The BMJ suggests that calcium supplements, vitamin D supplements, or taking both together provide little to no clinically meaningful benefit in preventing fractures or falls for most older adults. ...continue reading "Large Study Finds Vitamin D and Calcium Supplements Do Not Prevent Fractures"

Credit: Wikimedia Commons

The topic of farts is rarely discussed in adult conversations. This is because passing gas or farting can be embarrassing to the person farting, especially when occurring in a public setting. One wonders: Is farting (flatulence) normal? How many farts per day is normal?

Research shows that releasing intestinal gas through the rectum (farting) is part of normal and healthy digestion. On the other hand, "excessive farting" could be a sign of some sort of intestinal problem. Two recent studies examined "normal farting" and came up with different results. An Australian study found that overall people reported 5 farts per day using a "Chart your fart" app, but a Maryland study had participants wear special "smart" underwear that measured any passing of gas and came up with 32 farts per day!

From Medscape: Flatus Status: How Many Farts a Day Is Normal?

Researchers Emily Brindal and Danielle Baird developed the “Chart Your Fart” app as a citizen-science initiative.

The app allows people to log their emissions in real time, and to (optionally) rate them in terms of stench, loudness, duration, and — critically — detectability. Which is obviously necessary to determine whether he who smelt it actually dealt it. ...continue reading "Farting Is Perfectly Normal"

Vitamin D supplements are available in both D2 and D3 form. Research has long supported that it's vitamin D3 that has health benefits, and that vitamin D2 doesn't do anything. Well... a recent study found that vitamin D2 actually has a negative effect - that it lowers how much vitamin D3 the body absorbs.

Ingesting vitamin D2 supplements results in lower levels of vitamin D3 in the blood - measured as  serum vitamin 25(OH)D3 concentrations.  Note that Vitamin D3 is the form of vitamin D synthesized in human and animals skin upon exposure to ultraviolet B (UVB) radiation from sunlight. Thus, vitamin D3 is the form of vitamin D that our body naturally produces from sunlight and then use.

All the more reason to avoid vitamin D2 (ergocalciferol), and instead only take vitamin D3 (cholecalciferol). Read the ingredients list on the bottle!

From Science Daily: Scientists warn popular vitamin D supplement may have a “previously unknown” downside

Taking vitamin D2 might lower the body's levels of the more efficient form of vitamin D, vitamin D3, according to new research from the University of Surrey, John Innes Centre and Quadram Institute Bioscience. Many people take vitamin D supplements to support their bone and immune health and meet the UK government recommendation of 10 micrograms (µg) each day, especially during the winter months. ...continue reading "Research Finds Vitamin D3 to Be Beneficial, But Not Vitamin D2"

Vitamin C pills Credit: Wikipedia

Researchers are studying high dose vitamin C as part of treatment for several cancers, including pancreatic cancer. These high doses of vitamin C (pharmacologic ascorbate) are not taken orally (by mouth), but in IVs (taken intravenously). It is always given alongside chemotherapy.

The intravenous vitamin C doses are 150 to 190 times larger than ordinary vitamin C tablets that are taken orally. This is because orally taken vitamin C cannot reach the blood levels needed to produce a pharmacologic effect.

Some of the results are amazing. For example, persons with pancreatic cancer it doubled survival compared to chemotherapy alone (from 8 months to 16 months) , and those receiving vitamin C used alongside standard chemotherapy had fewer side effects than when using chemotherapy alone. It is still unclear for which cancers the vitamin C treatment works and for which it doesn't.

The only problem is that pharma companies may not be interested because it can not be patented, and can't be developed as a new drug that they can make big profits off of. It's plain old vitamin C - but not as a nutritional supplement, but used as a medical drug (pharmacologic ascorbate).

Click on the link for the full story and dosing details. Excerpts from Medscape: Vitamin C’s Potential Use in Cancer Is Getting a Second Look

When Garry Buettner, PhD, who has been studying the chemistry and biochemistry of vitamin C for at least four decades, was diagnosed with myelodysplastic syndromes (MDS), he applied his research to his own life — reviewing the data and designing a protocol for his treatment. ...continue reading "High Dose Vitamin C As Part of Cancer Treatment?"

Remember when health advice was to limit egg consumption, that they had too much cholesterol, and to only eat egg whites? Well.... studies in the last decade have proven that advice as being 100% wrong for a number of reasons. It turns out that eggs are a great source of a number of nutrients (e.g., choline) needed for brain health and memory function.

A recent study found that frequent egg consumption by persons (mean age 59 years at the start of the study) lowers the risk of developing Alzheimer's disease (AD). The researchers found that there was a 27% decreased risk of developing Alzheimer's disease among persons who ate at least 5 eggs a week, but even eating fewer eggs was beneficial. The participants were followed for 15 years.

Other studies have also found a decreased risk of AD in persons eating eggs frequently - with one study finding that more than one egg consumed per week reduced the risk of developing AD up to 47%.

Some key nutrients necessary for brain health that are provided by eggs are: choline, the carotenoids lutein and zeaxanthin, tryptophan, phospholipids, and an omega-3 fat known as DHA (docosahexaenoic acid). The researchers viewed the nutrients in eggs as being "neuroprotective" (protecting neurological function).

From Medical Xpress: Egg consumption associated with a lower risk of Alzheimer's disease

Consumption of eggs is associated with a lower risk of being diagnosed with Alzheimer's disease for those 65 years and older, according to researchers at Loma Linda University Health. Eating one egg per day for at least five days a week reduces the risk of Alzheimer's by up to 27%, researchers found. ...continue reading "Egg Consumption Is Beneficial For Brain Health"

Many people load up on all sorts of supplements thinking it'll give them better health and perhaps even extend their life span. But researchers found that one popular anti-aging supplement (known as spermidine) thought to extend the life-span could also be fueling the growth of cancer. How can this be?

The researchers found that the effects of polyamines (including spermidine), which are in all living cells, can either promote healthy aging or can fuel cancer growth. The difference was in which protein they influenced, and whether the cells were healthy to start with. In healthy cells they support cellular maintenance and energy production but in cancer cells they help drive rapid growth.

From Science Daily:  Scientists reveal why a popular anti-aging compound may also fuel cancer

Polyamines are naturally produced molecules present in all living cells. They play a vital role in basic biological functions, including cell growth and specialization. In recent years, scientists have focused on these compounds, especially spermidine, for their potential to support healthy aging. Often described as 'geroprotectors,' they have been shown to stimulate autophagy, a cellular recycling process that clears out damaged components. This benefit largely depends on a protein called eukaryotic translation initiation factor 5A (eIF5A1).

At the same time, researchers have repeatedly observed high levels of polyamines in many types of cancer, where they are linked to aggressive tumor growth. This contrast has created a scientific puzzle. How can the same molecules that appear to promote longevity also be associated with cancer?
...continue reading "Study Finds Popular Anti-Aging Supplement Could Also Fuel Cancer Growth"