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Mammography image Credit: National Cancer Institute

Women have been advised by their doctors to get frequent mammograms for decades. However, what if frequent (e.g., annual) mammograms result in an increased risk for breast cancer due to exposure to X-rays? After all, there is a cumulative dose from the mammograms - year after year you get exposed to a little ionizing radiation, but it builds up over time.

Dr. Seth Hardy (radiologist and Associate Professor at Penn State Univ.) discusses this issue, while referencing research by Dr. Daniel Corcos about the possibility of some breast cancers occurring from the cumulative radiation from previous mammograms. This is because radiation is a carcinogen (can cause cancer).  [NOTE: studies find that over the years breast cancer treatments have so improved that any benefits of mammography screening are diminished.]

From Dr. Seth Hardy, writing at Sensible Medicine: The Ethics of Screening Mammography

The value of breast cancer screening with mammography is increasingly being questioned. Women are trying to decide what is right for them and the USPSTF is trying to decide what is worthy of reimbursement. Currently, the medical literature is at a stalemate.[1]1 ...

Screening mammography uses ionizing radiation, a known carcinogen. The dose of radiation in each exam is very low, but exposure is cumulative. Also, the absorbed dose varies with the density of the breast. Women with more glandular tissue receive a higher exposure. Thus, over decades of screening, radiation exposure may not be trivial, particularly in women with extremely dense breasts

Across a population there is some percentage of breast cancers which are caused by screening mammography. The exact number is the subject of debate and not well studied. One article from 2011 approximates 86 cancers and 11 deaths per 100,000 women due to breast cancer screening. Another paper estimates 20-25 fatalities for 100,000 women screened starting at age 40. Due to lack of data, and ethical limitations in obtaining more data, we do not know how many breast cancers are caused by screening. ...continue reading "Can Mammograms Increase Risk of Breast Cancer?"

Most Americans eat highly processed or ultra-processed foods every single day, with most of their daily calories from them! There are all sorts of health risks from these foods, with a recent study finding an overall increased risk of cancer, as well as prostate and breast cancer.

Emulsifiers are food additives found in many ultra-processed foods. A large French study found that higher intakes of the emulsifiers carrageenan, mono and diglycerides are linked to an overall increased risk of cancer, as well as an increased risk in prostate and breast cancers.

Bottom line: Read the ingredients listed on labels! As much as possible, try to only buy and cook foods with ingredients that you would find in a kitchen. For example, flour, sugar - yes, chemical sounding names - no.

From Medscape: Are Food Emulsifiers Associated With Increased Cancer Risk?

...continue reading "Food Additives and Higher Cancer Risk"

People worry about breast cancer and whether exposure to chemicals "in the environment" can lead to breast cancer. According to many studies the answer is: YES, absolutely - and this is why they are called carcinogens (a substance capable of causing cancer). What are the chemicals?

A recent study found that 921 chemicals are likely "breast carcinogens" and thus increase the risk of breast cancer. Many of these are commonly used in everyday products, including personal care products. The authors also pointed out that this list of chemicals is incomplete because information is not publicly available on many additional chemicals . (Unfortunately, the EPA is not asking for more information and testing to be done on many chemicals.)

The authors of the study point out  that breast cancer is "both the most commonly diagnosed cancer type and leading cause of cancer death among women worldwide". So knowing which chemicals could potentially cause breast cancer is important. Some examples: phthalates, parabens, many pesticides, endocrine disruptors.

Bottom line: Read ingredient lists in order to avoid many problematic chemicals. For example; if you see parabens or phthalates listed (e.g., in lotion) - avoid those products. Avoid fragrances, stain repellents, antimicrobials. Eat as many organic foods as possible (to avoid pesticide residues in non-organic foods). [See more tips on avoiding toxic chemicals.]

Also, avoid using pesticides as much as possible, and instead use least toxic Integrated Pest Management (IPM) or organic methods, both inside the home and outside.

Excerpts from Environmental Health News: More than 900 common chemicals linked to breast cancer risk: Study

More than 900 chemicals commonly found in consumer products and the environment have been linked to breast cancer risk in a new study. ...continue reading "Hundreds Of Common Chemicals Are Linked to Breast Cancer Risk"

Do you know what chemicals you're exposed to on a daily basis? A recent study found that women with cancers of the breast, uterus, skin (melanoma), or ovaries had significantly higher levels of certain endocrine disrupting chemicals in their bodies than women without any of those cancers.

The researchers looked at levels of some hormone disrupting chemicals: PFAS (per- and polyfluoroalkyl substances), phenols (e.g. BPA), and parabens in both men and women. They found that women had higher levels of endocrine disruptors for 4 types of cancers (breast, uterine, ovarian, and melanoma). However, there was no relationship between the endocrine disruptors and thyroid cancer in men or women, and no relationship in men with prostate cancer.

The reason the researchers looked at breast, prostate, thyroid, ovarian, endometrial, and testicular cancers, and melanoma is because they are "hormone-mediated" cancers. That is, hormones play a role in growth and progression of these cancers.

Bottom line: You cannot totally avoid these chemicals because they are used in so many products, but you can really lower your exposure to them. Read Avoiding Harmful Chemicals for easy tips on reducing your exposure to these harmful chemicals. For example, don't use non-stick pots and pans, don't use plug-in air fresheners, and try to use fragrance-free or unscented products as much as possible. Use paraben and phthalate-free personal care products.

From Medical Xpress: Study finds significant chemical exposures in women with cancer

In a sign that exposure to certain endocrine-disrupting chemicals may be playing a role in cancers of the breast, ovary, skin and uterus, researchers have found that people who developed those cancers have significantly higher levels of these chemicals in their bodies. ...continue reading "Some Cancers In Women Linked to Chemical Exposures"

For years there has been much concern over chemicals that act as endocrine disruptors (hormone disruptors) in the personal products that we use on a daily basis.  One big concern is whether these chemicals, such as parabens and phthalates, are causing breast cancer (as well as other harmful health effects). Because whatever you use on your skin, will get into you.

A recent study looking at these harmful chemicals found that women switching to paraben and phthalate free cosmetic products had a quick effect (within 28 days) on lowering their levels in the body (blood, urine, breast tissue cells). Which then resulted in lowering breast cancer markers to a "normal" expression. Wowza!

What you can do: Check the ingredients in the lotions you use. Are there parabens and phthalates in it? Spend your money on safe lotions and other personal products. Go to EWG (ewg.org) or mamavation.com for lists of safe products. Also: Ways to lower your exposure to harmful chemicals

For example, the commonly used lotion Lubriderm to this day has several types of parabens (e.g., methylparaben) in it. No, no, no... Why are they still in the lotion? Note that our government is not protecting us from these harmful chemicals. (Instead Big Business and big money is more important.)

From Environmental Health News: Get phthalates, parabens out of the bathroom drawer to reduce breast cancer risk: Study

Switching to phthalate and paraben-free personal care products could reduce the risk of developing breast cancer, according to new research. ...continue reading "Personal Care Products and Breast Cancer Risk"

The EPA has many serious problems, from protecting corporations and not consumers, to ignoring studies that find health problems with products or chemicals. Dr. Jennifer Liss Ohayon, a research scientist at Silent Spring Institute and Northeastern University, pointed out in a recent article that the EPA keeps approving pesticides linked to breast cancer.

These pesticides act as endocrine disruptors on the breast, with effects occurring at low doses. Many are commonly used (e.g., malathion, atrazine), which means women are exposed to in food, water, the workplace, and at home (yes - home, garden, and lawn chemicals!).

Why be concerned? Young women are experiencing earlier breast development, difficulty in breastfeeding, and increasing rates of breast cancer. Many studies link this in women (and in animals) with chemical exposures, especially endocrine disrupting chemicals (this is because they screw with hormones, and so have an effect on breast development and breast tissue).

But... the EPA is dismissing or ignoring relevant studies and pooh poohing the idea that chemicals can have harmful endocrine disrupting effects. Effects on the breast (mammary gland) are NOT required to be part of the EPA's chemical risk assessment (which determines whether a pesticide will be approved). The studies the EPA relies on are almost all financed by the manufacturers (hmmm...of course they'll say the pesticide is safe).

Note that the European Union bans many of the worrisome pesticides - they are not ignoring the science, and in doing so protect people.

From a piece by Dr Jennifer Liss Ohayon at Environmental Health News (EHN): Why is the EPA still exposing women to pesticides linked to breast cancer?

This fall marks the 60th anniversary of writer and scientist Rachel Carson’s 1962 book “Silent Spring.” The book was seminal in that it sparked the modern environmental movement, a U.S. ban of DDT, and the founding of the Environmental Protection Agency (EPA). However, despite decades passing since Carson first warned us about the dangers of pesticides, EPA continues to approve pesticides linked to breast cancer. ...continue reading "The EPA Is Still Approving Pesticides Linked To Breast Cancer"

Some dietary supplements can do serious harm, especially when taken in high doses. A recent study found cancer associated with high doses of the supplement nicotinamide riboside (NR), which is a form of vitamin B3.

Keep in mind that this study was done in vivo and in vitro (in a lab), and also in mice.. and not humans. But the results are concerning.

Swiss and Univ. of Missouri researchers found that high levels of NT could increase the risk of developing triple-negative breast cancer, and also for it to metastasize to the brain. Yikes.

By the way, while NR can be purchased as a supplement, it is normally not found in ordinary multi-vitamins that many take daily. Low levels of NR are found in fruit, vegetables, meat, and milk - it is necessary for health (it increases levels of cellular energy). It's the large amounts found in supplements that the researchers were concerned with and that can be problematic.

Stay tuned for further research...

From Science Daily: Popular dietary supplement increases breast cancer risk, brain metastasis, study suggests

While previous studies have linked commercial dietary supplements like nicotinamide riboside (NR), a form of vitamin B3, to benefits related to cardiovascular, metabolic and neurological health, new research from the University of Missouri has found NR could actually increase the risk of serious disease, such as development of breast cancer and brain metastasis. ...continue reading "A Dietary Supplement That Might Increase Cancer Risk"

Normal (left) vs cancerous breast (right), mammography image
Credit: National Cancer Institute

This is very preliminary, but everyone is excited over a breast cancer vaccine now being tested. The vaccine is meant to treat women who have breast cancer.

University of Washington researchers tested the vaccine for safety (it was very safe) and to see what was a good dose for women in a Phase 1 Clinical Trial. But the 66 women it was tested on (all who had metastatic breast cancer that had been treated) overall did much better than expected. Fabulous!

The next trial will soon start (Phase 2) with women at different stages of breast cancer. Stay tuned!

From Medical Xpress: Breast cancer vaccine safely generates anti-tumor immunity

An experimental vaccine against breast cancer safely generated a strong immune response to a key tumor protein, researchers from the University of Washington School of Medicine in Seattle report in a paper published by the journal JAMA Oncology. The findings suggest the vaccine may be able to treat different types of breast cancer.

"Because this was not a randomized clinical trial, the results should be considered preliminary, but the findings are promising enough that the vaccine will now be evaluated in a larger, randomized clinical trial," said lead author Dr. Mary "Nora" L. Disis, a UW professor of medicine, Division of Medical Oncology, and director of the Cancer Vaccine Institute. ...continue reading "Breast Cancer Vaccine Now Being Tested"

We all know that microbes (fungi, viruses, bacteria) live throughout our bodies - this is the human microbiome or microbiota. What is really interesting is that cancer tumors also have microbiomes (tumor microbiome), and these microbial communities are different than that found in healthy people (without tumors).

For a while it has been known that tumors (e.g., breast cancers) have different bacterial species than healthy tissue - the microbiome is different. Several recent studies find that tumors can also contain fungi, and cancers with certain fungal species have worse outcomes than those without the fungi. The mycobiome is the community of fungi that live in or on humans.

Also, the combination of fungal species are different depending on what kind of cancer that a person has. A group of scientists have put together a list (mycobiome atlas) of the distinctive fungi that are found with 35 different cancer tumors. This is exciting because in the future cancers could potentially be found by the microbial (fungi and bacteria) DNA they shed in the blood.

However, no one knows really why the fungi are in the tumors. For example, are they aiding the cancer development? Or is the cancer allowing the fungi to grow? Are the fungi interacting with the immune system? Or??

Several recent articles discuss this exciting new research.

From NY Times: A New Approach to Spotting Tumors: Look for Their Microbes

Look up an image of a tumor on Google, and you’ll probably end up with a brightly colored cluster of cancer cells on a drab background of healthy tissue. But for Lian Narunsky Haziza, a cancer biologist at the Weizmann Institute of Science in Israel, the picture looks very different. A tumor may also contain millions of microbes, representing dozens of species.

Scientists have long known that our bodies are home to microbes, but have tended to treat tumors as if they were sterile. In recent years, however, researchers have laid that notion to rest, demonstrating that tumors are rife with microbes. ...continue reading "Studies Find Fungi In Cancer Tumors"

We've all been warned over and over to avoid sunlight in order to avoid skin cancer, but... conflicting with that advice are studies linking higher sunlight exposure to lower levels of other cancers, health benefits (e.g. lower blood pressure), and early death (mortality). One such recent study found that higher sun exposure over the years is associated with a lower risk of breast cancer in women.

The Univ. of Buffalo and Univ. of Puerto Rico researchers conducted the study in Puerto Rico, where people live with high year round sun exposure. 635 women participated in the study.

From Medical Xpress: Study in Puerto Rico finds lower risk of breast cancer with more sun exposure

The sun is almost always shining during the day in San Juan, Puerto Rico, and that makes the findings of a new study on breast cancer and sun exposure particularly noteworthy.  ...continue reading "Study Finds Lower Risk of Breast Cancer With Higher Sunlight Exposure"