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Several studies have recently been published that push back at the idea that all alcohol intake has negative health effects. Actual results are more nuanced. High alcohol intake is always harmful, but low to moderate intake appears to be protective for a number of health conditions. In fact, low to moderate intake appears to be better for health than totally abstaining from alcohol.

Similar to research reported in the last post, another recent study looking at alcohol consumption found that low to moderate alcohol consumption has beneficial health effects (is protective). Again, a J curve finding that low to moderate intake best delays biological aging (as measured by biomarker measurements), then alcohol never or rarely consumed, and finally that high intake was harmful - it canceled any alcohol protective effects. In other words, low to moderate alcohol consumption slows down aging.

The most beneficial effects were at 1 to 2 glasses of wine per day. These associations were predominantly in men, and these effects went hand in hand with eating a Mediterranean diet. The Mediterranean diet is eating a diet rich in fruits, vegetables, whole grains, nuts and seeds, beans, and olive oil. The researchers thought that compounds such as polyphenols in wine could play a role in why low to moderate alcohol consumption was beneficial.

From Medical Life Sciences News: Moderate wine intake tied to slower biological aging in men

A large Italian cohort study suggests that moderate wine intake, as defined within a traditional Mediterranean diet, may be associated with slightly slower biological aging in men, whereas total alcohol intake showed a different, less favorable pattern. ...continue reading "A Daily Glass of Wine Is Associated With A Slower Rate of Aging"

It seems that in the last few years all alcohol intake has been demonized, with warnings that any alcohol can increase the risk of cancer. What is not typically mentioned are the studies finding health benefits from consuming low to moderate levels of alcohol. Especially wine consumed with a meal.

Studies for years have found a J curve in health effects - with low to moderate levels of alcohol consumed best for health, and no alcohol or rarely consumed a little worse,  and high levels of alcohol consumption having the most negative health effects. In other words, low to moderate alcohol consumption (e.g., 1 glass wine daily) can be protective for certain health conditions.

The following study found that consuming low to moderate levels of wine is associated with a lower risk of cardiovascular disease and cardiovascular events, such as heart attacks, in older adults (mean age 68 years). Best was consuming between half a glass and one glass per day of wine - a 50% lower chance of cardiovascular events.

From Science Daily: New evidence on the relationship between moderate wine consumption and cardiovascular health

Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health. ...continue reading "Some Wine With Dinner Can Have Health Benefits"

Human brain Credit: Wikipedia

The risk of developing dementia increases as a person ages. According to the National Institute of Health (NIH) the risk of dementia was 4% by the time a person is 75, and 20% by age 85, and even higher after 85 years of age. Thus the interest in ways to prevent the onset of dementia, including Alzheimer's disease.

One way to lower the risk of Alzheimer's disease is getting vaccinated, including the shingles and flu vaccines, after the age of 60. A recent study found that getting vaccinated with high dose flu vaccines in adults 65 years and older (instead of standard dose) reduces the odds of developing Alzheimer's disease even more.

A possible reason for the protective effect of the flu vaccine, especially the high-dose vaccine, is that vaccination strengthens immune defenses and reduces inflammation. Inflammation is thought to play a role in the development of Alzheimer's disease.

Excerpts from CIDRAP: High-dose flu vaccine tied to lower Alzheimer’s risk in older adults

Receiving a high-dose flu vaccine is associated with a significantly lower risk of Alzheimer’s disease than a standard-dose vaccine in adults aged 65 and older, according to a large observational study published in Neurology. The findings add to a growing body of evidence linking vaccination, and possibly immune system activity, to reduced dementia risk. ...continue reading "High-Dose Flu Vaccines Lower the Risk of Developing Dementia"

Cup of coffee Credit: Wikipedia

Once again, a recent study found that daily consumption of coffee has health benefits.

Recent research found that drinking a moderate amount of coffee (2 to 3 cups of daily) or 1 to 2 cups of tea daily was associated with a lower risk of dementia and better cognitive function. Decaf coffee appeared to have no effect on risk of dementia or cognitive functioning.

Persons with the highest intake (2 to 3 cups or more daily) of caffeinated coffee had an 18% lower risk of dementia compared with those who drank little or no caffeinated coffee. The large study followed people for as long as 43 years.

From Medical Xpress: Consuming 2–3 cups of coffee daily associated with lower dementia risk, better cognitive function

A new prospective cohort study by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard analyzed 131,821 participants from the Nurses' Health Study (NHS) and Health Professionals Follow-Up Study (HPFS), finding that moderate consumption of caffeinated coffee (two to three cups a day) or tea (one to two cups a day) reduced dementia risk, slowed cognitive decline, and preserved cognitive function. ...continue reading "Consuming Coffee Or Tea Daily Associated With Lower Risk of Dementia"

MALE URINARY SYSTEM Credit: Wikipedia

Chronic kidney disease (CKD) is a growing problem globally, especially in aging populations. As people age, their kidney function declines - and this is a normal part of aging. A recent study found that physical activity slows this kidney function decline.

The study followed healthy individuals (aged 50 to 64 years at the start), who had varying physical activity levels, over an 11 year period. The researchers found that there is a dose response effect from physical activity - more active persons had a slower annual kidney function decline, as well as a much lower risk of accelerated kidney function decline.

The slowest level of kidney decline was in persons who were physically active almost every day (at least 5 days a week) and who engaged in more intense exercise. Note that physical activity is not just doing exercises - it's physical activity of all sorts. Yes, walking counts.

The researchers viewed physical activity as having reno-protective effects - in both the general population and in persons with CKD. This is because it lowers the risk of developing CKD, but it also slows kidney function decline. By the way, other studies have also found physical activity or exercise beneficial in slowing down the kidney function decline that occurs with aging.

From Medscape: Physical Activity May Slow Kidney Function Decline

Increased physical activity was associated with a substantially lower risk for kidney function decline, with the strongest effects seen with higher frequencies and intensities of activity, according to a new longitudinal study. ...continue reading "Physical Activity Slows Down Kidney Function Decline That Occurs With Aging"

Very depressing news. The EPA plans to NOT take into account of the value of human life any more when making rules and setting policy regarding air pollutants (e.g., fine particulate matter and ozone). Meaning that the value of a human life is zero dollars. Instead, the only thing that will be considered is the cost to businesses of pollution regulations.

In other words, no more estimates of the dollar value of lives saved in the cost-benefit analyses for new pollution rules. People dying will just be a side-effect of business - eh, move on, nothing to see here.

This means that the cost to society (of human suffering and deaths) from pollutants just doesn't matter. Businesses obviously do not/will not want regulations that cost money.  Yes, this will mean dirtier air and the environment going forward. Very depressing...

Excerpts from NY Times: Trump’s E.P.A. Has Put a Value on Human Life: Zero Dollars

Government officials have long grappled with a question that seems like the purview of philosophers: What is the value of a human life?

Under both Democratic and Republican administrations, the answer has been in the millions of dollars. The higher the value, the more the government has required businesses to spend on their operations to prevent a single death.

But for the first time ever, at the Environmental Protection Agency the answer is effectively zero dollars. ...continue reading "The EPA Now Values Human Life At Zero Dollars"

The health benefits of regularly drinking coffee keep increasing. A recent study confirmed that consuming coffee on a regular basis reduces the incidence of liver disease and slows the progression of several liver diseases.

The study authors write that coffee contains a number of bioactive compounds (e.g., caffeine, polyphenols, diterpenes) which have "anti-inflammatory, antioxidant, antifibrotic, and anticancer properties".

In other words, enjoy your daily coffee. It's good for you!

Excerpts from Medscape: Regular Coffee Drinking Can Protect and Restore Liver Health

TOPLINE: Several bioactive compounds in coffee exert antioxidant, anti-inflammatory, antifibrotic, and metabolic effects that reduce the incidence and progression of liver diseases. ...continue reading "Coffee and Liver Health"

Great news for cheese lovers! A recent study found regularly eating full-fat (high-fat) cheese and cream was associated with a lower risk of developing dementia. Some examples of full-fat cheese include cheddar, Swiss, Parmesan, Brie, Gouda, Provolone, Colby, Havarti, Mozzarella (full-fat), and cream cheese.

This was a long-running study (27,670 persons for 25 years) conducted in Sweden. High-fat cream and cheese consumption was inversely associated with dementia, Alzheimer's disease, and vascular dementia. Eating more than 50 grams (about 1/3 cup or 2 slices) of full-fat cheese per day was associated with a 13% to 17% lower risk of Alzheimer's, and more than 20 grams (about 1 1/2 tablespoons) of full-fat cream was linked to a 16% lower risk of dementia overall.

However, consumption of low-fat cheese, low-fat cream, milk (low or high fat), and butter showed no association with dementia.

From Science Daily: Study links full-fat cheese to lower dementia risk

...continue reading "High Fat Cheese and Lower Risk of Dementia"

For years it has been known that increasing the amount of fiber (and drinking enough fluids) in a person's  diet helps to prevent constipation. A recent large multi-year study of 96,000 adults confirmed this: Mediterranean and plant-based diets prevented constipation, and Western and inflammatory diets (low fiber, high ultra-processed foods) raised constipation risk.

Vegetables, cruciferous vegetables (e.g., broccoli), legumes (beans, lentils, chickpeas), and fruits were all associated with reduced risks for constipation. High vegetable and nut consumption was especially good for preventing constipation. Additionally, a low carbohydrate diet showed a slight increased risk for constipation. Eating a diet rich in cereal fibers (e.g., white bread, low fiber breakfast cereals) and ultra-processed foods was linked to constipation.

Besides reducing constipation, many studies show that eating a diet rich in fruits, vegetables, whole grains, seeds, nuts, legumes, such as the Mediterranean diet, is protective for cardiometabolic diseases (e.g., heart disease, heart attack, strokes, kidney disease, and type 2 diabetes), cancer, and even early death. This type of diet is high in fiber, has positive effects on the gut microbiome, and reduces chronic inflammation.

From Science Daily: What 96,000 adults taught scientists about preventing constipation

Chronic constipation becomes more common with age. Researchers from Mass General Brigham conducted a new study examining whether five widely followed diets could help prevent chronic constipation in middle- and older-age adults. The team monitored more than 96,000 participants for several years to see how long-term eating habits influenced the likelihood of developing this persistent gastrointestinal issue. Their analysis showed that people who routinely ate a Mediterranean or plant-based diet experienced a lower incidence of constipation. The findings appear in Gastroenterology. ...continue reading "The Foods You Eat and Their Link to Constipation"

The evidence keeps piling up that certain foods are associated with health, while other foods (e.g., soda, ultra processed foods) are associated with chronic diseases. A recent article reported the results of several studies finding certain foods linked to cardiovascular health, including lowering blood pressure.

But guess what? They are popular foods available to everyone - cocoa, green tea, black tea, apples, grapes, and berries.

There is strong evidence certain plant compounds (flavan-3-ols, also known as flavanols or catechins) in these foods have beneficial effects on cardiovascular health. These compounds can lower blood pressure and improve endothelial function (functioning of the blood vessels). Two to three cups of tea daily! One to two servings of dark chocolate daily! Instead of chips for a snack, have an apple.

By the way, rather than focusing on eating just certain foods, it's better to improve your entire diet by eating more fruits, vegetables, whole grains, legumes, seeds, and nuts. All these foods are linked to good health and are considered part of a heart-healthy diet.

From Medscape: From Apples to Cocoa: Everyday Foods Linked to CV Benefits

The term “healthy diet” is often used but frequently remains vague. This is why scientific research into specific food components with preventive potential is gaining importance. Current studies suggest that certain plant compounds found in everyday foods such as apples, cocoa, and tea may have beneficial effects on cardiovascular (CV) health. ...continue reading "Common Foods Linked to Improved Heart Function"