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Category: endocrine disruptors

Published on Leave a comment on Some Common Chemicals Alter the Gut Microbiome

This is rarely mentioned, but there is research showing that commonly used chemicals that we are exposed to, such as bisphenols (BPA, BPS), phthalates, persistent organic pollutants (e.g.flame retardants, nonstick cookware), heavy metals (e.g. lead), and some pesticides (e.g.chlorpyrifos, glyphosate), all have an impact on the gut microbiome in animals and humans.

For example, these chemicals may alter levels of certain microbial species, or alter the variety (diversity) and type of species in the gut, or increase intestinal inflammation. These alterations are associated with health effects, and the effects may be different depending on the stage of life. Yikes!

The human gut microbiome is the huge and complex community of microbes (fungi, bacteria, viruses) that live in our intestines and play important roles in our health. Trillions of microbes, hundreds of species. The presence of certain microbial species in the gut are associated with health, and the presence of certain other species are associated with disease. We know that what we eat and drink, whether we exercise, and other lifestyle factors can influence the gut microbes, but it appears we also need consider exposure to chemicals in the environment around us.

A recent study by University of Illinois researchers reviewed the environmental chemical and microbiome research, and found that many chemicals have an effect on the gut microbiome. They point out that humans are constantly exposed to hundreds of chemicals in the environment, and many get into humans (through inhalation, ingestion, absorption through the skin). Currently more than 300 environmental chemicals and their metabolites have been measured in humans (e.g. in blood and urine).

Many of these chemicals are endocrine disruptors, and many are associated with adverse health effects, including male and female reproductive and developmental defects, type 2 diabetes, cardiovascular effects, liver disease, obesity, thyroid disorders, and immune effects.

By the way, gut microbiome effects are currently not considered by the EPA when regulating chemicals.

From Science Daily: Environmental contaminants alter gut microbiome, health

The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants. In a new paper, scientists from the University of Illinois at Urbana-Champaign review the research linking dozens of environmental chemicals to changes in the gut microbiome and associated health challenges.  ...continue reading "Some Common Chemicals Alter the Gut Microbiome"

Published on Leave a comment on Lower Your Pesticide Levels By Eating Organic Foods

organic grains, oatsAchieve dramatically lower pesticide levels in your body in a few days! No need for "colonics" or "detox regimens". All one has to do is eat organic food to lower pesticide levels! And the more organic food in the diet, the better.

We ingest small amounts of pesticides when we eat and drink conventionally grown foods, and these pesticides can be measured in our urine and blood. Studies have found that switching to an organic diet lowers the amounts of pesticides (e.g. chlorpyrifos, 2,4-D) in the body, and now glyphosate (the active ingredient in Roundup) can be added to the list. This is because glyphosate is used to grow conventional foods, but it is not allowed to be used on organic crops or in organic food production.

A recent study found that eating an all organic diet lowered glyphosate and AMPA (glyphosate metabolite) levels, in both adults and children, more than 70% in 6 days. The study measured glyphosate and its metabolites (in the urine) in members of 4 families who typically did not eat organic food, and who lived in different parts of the US. During the organic phase lasting 6 days, all the food the 16 people ate was organic - it was provided to them.

Before the organic phase of the study, both glyphosate and AMPA (glyphosate metabolite) were detected in more than 93.5% of urine samples in the study participants. Glyphosate and AMPA levels were substantially higher in children than in their parents, and this was true in both the conventional and the organic diet phases of the study, even after levels went down. The researchers thought that perhaps children were getting more environmental exposures (parks and school grounds), or perhaps they metabolize the pesticide slower than adults. (It's unknown why.)

Glyphosate has been linked to cancer, to effects on the kidneys and liver, endocrine disruption, and alteration of the gut microbiome. The overwhelming majority of people have glyphosate or its metabolites in their bodies. We get pesticides into our bodies through inhalation, absorption through the skin, and we ingest them in foods and beverages. As more and more glyphosate is used each year on crops, the levels in our bodies have been increasing. ...continue reading "Lower Your Pesticide Levels By Eating Organic Foods"

Published on Leave a comment on Common PFAS Chemical Exposure and Age At Menopause

Does exposure to common PFAS chemicals contribute to an earlier age for menopause? A recent University of Michigan study found an association between blood levels of PFAS (per-and polyfluoroalkyl substances) in women and age at menopause. Women with the highest levels of PFAS in their blood had menopause 2 years earlier than those with lower levels.

PFAS are commonly known as "forever chemicals" because they persist in the environment and in humans. These chemicals have been widely used in many industrial and consumer products, such as non-stick cookware and food packaging, including microwave popcorn bags. They are also endocrine (hormone) disruptors and are thought to have an effect on ovarian aging.

What you can do: Don't microwave food, including popcorn, in the packaging it came in. Use microwave safe dishes instead.  Also, avoid nonstick cookware, and instead use plain stainless steel cookware.

From Science Daily: PFAS exposure may cause early menopause in women

Per- and polyfluoroalkyl substance (PFAS) exposure may cause menopause to occur two years earlier in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.  ...continue reading "Common PFAS Chemical Exposure and Age At Menopause"

Published on Leave a comment on Certain Chemicals Linked to Celiac Disease

Worried about the effects of persistent pesticides, flame retardants, and the chemicals used in non-stick pans (e.g.Teflon) on human health? An interesting small study from researchers at New York University looked at whether there is a link between having higher levels of these chemicals and celiac disease (a digestive disorder in which there is an abnormal response to foods with gluten). And yes, they found one.

Certain pesticides, flame retardants (PBDEs), and nonstick chemicals (PFASs) are known as persistent organic pollutants (POPs). They are known to be endocrine disruptors (meaning they disrupt the hormonal system). The researchers think that because there is an interplay between endocrine and immune systems, then perhaps these chemicals may contribute to the development of celiac disease in people who are genetically susceptible to it.

Thirty children and young adults newly diagnosed with celiac disease were compared to 58 individuals without the disease.  Higher levels of these chemicals were found in the blood in those with celiac disease, when compared to those without celiac disease.

More reasons to avoid non-stick pots and pans, avoid flame retardants, avoid using pesticides on lawns, and to eat organically raised foods.

From Futurity: CELIAC DIAGNOSIS MORE LIKELY WITH HIGHER BLOOD LEVELS OF PESTICIDES

Children and young adults with high blood levels of pesticides—and with high levels of pesticide-related chemicals called dichlorodiphenyldichlorethylenes—were twice as likely to receive a new diagnosis of celiac disease than those without high levels, report researchers.  ...continue reading "Certain Chemicals Linked to Celiac Disease"

Published on Leave a comment on Tips For Reducing Exposures to Harmful Chemicals

Did you know that our modern lifestyle is exposing us to thousands of harmful chemicals? All of us are exposed to many harmful chemicals daily - in ordinary household products, at work and school, in our food, and in the air and water around us. These chemicals are found in plastics, in stain resistant finishes, non-stick cookware, flame retardants, fragrances, pesticides, water resistant finishes, and antimicrobial products.

All these chemicals have made our lives easier in many ways, but they have a dark side. The chemicals leach out of the products and get on us and in us, and can be measured in our blood and urine.

They are linked to all sorts of health problems (reproductive effects, infertility, neurological effects, lower IQs, immunological problems, cancers, etc.) and the list is growing annually. Many are hormone (endocrine) disruptors. Developing children and fetuses are especially vulnerable, and the effects can be life-long.

We all have many of these harmful chemicals in our body. No one can totally avoid all these chemicals, but we can lower our exposure to many of them quite a bit. These chemicals get in us various ways: we ingest them (in food and water), we absorb them through the skin, and we breathe them in (e.g. in household dust and in the air).

Many chemical levels can be reduced quickly - within a few days or weeks (for example, by switching to different personal care products, switching to organic foods, and not eating canned foods).

It is especially important to lower exposures to these harmful chemicals if you are considering conceiving a child, are pregnant, or have children. Many of these chemicals are linked to fertility problems for both men and women, and researchers think this is why male fertility is dropping so rapidly over the past few decades.

Yes, it does require a life-style change, and it does require reading labels, but it is worth it. Following these tips should also have the added bonus of improving your gut microbial communities. It's all related.

HOW TO REDUCE EXPOSURE TO HARMFUL CHEMICALS:

IN GENERAL - Try for a more “natural and non-toxic” lifestyle, and reduce use of plastics (including vinyl) and pesticides.

  • Read labels of personal care products, household products, and clothing. Avoid products with parabens and oxybenzone. Avoid products that are antimicrobial, antibacterial, anti-odor, anti-stain, anti-mildew, and nonstick.
  • Use unscented or fragrance-free products, including personal care products. Avoid fragrances or scented versions of products.
  • Don't use air fresheners, dryer sheets, scented candles, incense, essential oils.

FOOD

  • Buy foods and beverages in glass bottles and jars whenever possible.  Store food in glass, stainless steel, or ceramic containers. Avoid plastic bottles and containers.
  • Avoid canned foods, including aluminum cans - they are all lined with plastics containing BPA or equally bad BPA alternatives. Canned foods are a major source of endocrine disruptors.   ...continue reading "Tips For Reducing Exposures to Harmful Chemicals"

Published on Leave a comment on Flame Retardant Chemicals Have Harmful Effects Before Birth

Please, only buy or use sofas and upholstered chairs that do NOT contain any flame retardant chemicals. Be sure to look at the tags attached to the furniture that are required by a California law since 2015 (called Technical Bulletin 117-2013) to be on each new sofa and upholstered furniture. It will tell you if it contains flame retardant chemicals or not.

This is especially important if at some point you are thinking of having a child, if you are pregnant, or if you have children. The problem is that the flame retardant chemicals, which were added for decades to the foam in upholstered furniture, migrate out and so get into us (through the skin, inhaling, or by swallowing). Unfortunately, almost all of us have flame retardants in our bodies.  Where they can cause health problems.

Two new studies were published recently showing harms from exposures to flame retardants. The first found an association between flame retardant chemicals before birth (when the pregnant woman is exposed, it gets to the developing baby) and later reading problems.

The second study found that exposures to pesticides and flame retardants have overtaken  lead and mercury as leading contributors to IQ loss in children.

The researchers looked at exposure to major groups of endocrine disrupting chemicals during pregnancy and effects on the children. Yes - once again, chemicals frequently found all around us are hormone disruptors, and these chemicals also negatively affect neurological development. One result with higher exposure is that it lowers IQ. The 4 groups are: flame retardants (polybrominated diphenyl ethers or PBDEs), certain pesticides (organophosphates), mercury (methymercury), and lead. Exposures to the first three have the biggest effect during pregnancy (they cross the placenta and so get to the baby).

The researchers found an interesting result: organophosphate pesticide (such as chlorpyrifos) exposure and IQ loss attributed to it has increased since 2003. And that since the EPA did not ban chlorpyrifos (widely used on crops), then organophosphate pesticide "levels will continue to climb in the United States population due to ingestion of chlorpyrifos-treated crops". NOTE: these pesticides are allowed on conventional crops, but NOT organic crops.

How to avoid exposure? Hard to totally avoid exposure to these chemicals, but you can lower your exposure. Eat as many organic foods as possible. Try to avoid buying or having flame retardant sofas, upholstered chairs, and other upholstered furniture in your home. [Note: if they say that they use "safer" replacement chemicals - still avoid that furniture. The replacements are similar chemicals and may be just as bad or worse.] Frequently open windows to "air out" the home.

Excerpts from Science Daily: Prenatal exposure to flame retardants linked to reading problems   ...continue reading "Flame Retardant Chemicals Have Harmful Effects Before Birth"

Published on Leave a comment on Is the Replacement For BPA Even Worse?

Think that BPA-free products are safe? Oops... it doesn't look like it. The most common replacement for the commonly used chemical compound BPA (bisphenol A) is BPS (bisphenol S). But it has become very clear that both are hormone disrupting chemicals with numerous and harmful health effects, especially reproductive disorders.

BPA and BPS are plasticizers used in products all around us, for example in food packaging containers, water bottles, baby bottles, can linings, toys, personal care products, cash receipts, dental sealants and on and on. Because it leaches out of products, BPA has been detected in the urine of nearly every person tested, as well as in breast milk, amniotic fluid, the placenta, and the blood of pregnant women (meaning it's getting to developing babies and causing effects).

Thus the desire for BPA-free products, and why industry has substituted chemically related BPS. But BPA-free doesn't mean it's safe or without problems if BPS or BPSIP (another chemically related substitute) are used. Similar chemicals often cause similar problems, which is what is happening. BPS is also being found in the urine of the great majority of people tested (which means humans are being widely exposed to it).

Research using BPS has been worrying - it actually seems to be worse for health than BPA. The latest research (by University Of Guelph researchers), which was conducted on mice, suggests that BPS has rapid effects (in a negative way) on heart functioning. Within minutes of exposure (at levels comparable to typical human exposure), heart function worsened, especially in female mice.

What can you do to lower exposure to hormone disruptors BPA and BPS? One can't avoid chemicals such as BPA and BPS totally, but you can definitely lower your exposure by taking the following steps (as much as possible). The good news is that BPA and BPS leave the body rapidly - so the goal should be to try to limit new exposure.

SOME STEPS FOR LOWERING EXPOSURE: 1) Assume that a "BPA-free" product is using similar hormone disruptors (such as BPS) and so avoid it. 2) Buy and store food in glass or stainless steel containers (and not in plastic containers). 3) Use ceramic or glass plates in the microwave. Don't use any sort of plastic containers or pouches in the microwave. 4) Use fragrance-free products. Avoid products with fragrances in them, including air fresheners, scented candles, detergents, dryer sheets, and personal care products. 5) Avoid flexible vinyl (e.g. shower curtains - use cloth shower curtains and liners instead), 6) Use glass baby bottles, and 6) Wash hands before eating (everything gets on the hands!).

From Medical Xpress: BPA replacement hinders heart function, study reveals   ...continue reading "Is the Replacement For BPA Even Worse?"

Published on Leave a comment on Pregnancy, Endocrine Disrupting Chemicals, and Lower IQ

The evidence is building, study by study, that we are all exposed to a mixture of hormone disrupting chemicals (endocrine disruptors) on a daily basis, and that these have serious health effects, including on the developing fetus during pregnancy. Researchers found that early prenatal exposure to a mixture of endocrine disrupting chemicals  was associated with lower levels of cognitive functioning (lower IQ scores) at age seven, particularly among boys.

Researchers in New York City and Sweden looked at the impact of 26 endocrine disrupting chemicals during pregnancy on 718 Swedish mother-child pairs. It appeared that the higher the exposure during pregnancy, the more of an effect at age 7. Especially harmful was the BPA replacement chemical BPF - this is because it is chemically related to BPA.

Endocrine disrupting chemicals (EDCs) include bisphenols (BPA and its replacement  chemicals, such as BPF - used in products called "BPA free"), phthalates (especially used in vinyl products), parabens, chemicals used in flame retardants and non-stick coatings,  and some pesticides (e.g. the commonly used chlorpyrifos).

Especially worrisome is that while scientists typically test chemicals one at a time to determine their safety, in the real world we are all exposed to mixtures of these chemicals in our food, consumer products (including personal care products and cosmetics), and environment. Some of these chemicals can cross the placenta during pregnancy and so have an effect on the developing the fetus, including brain and neurological development. Yes, some of these chemicals are only in the body for a short time, but during critical developmental  stages, the effects can be big - even at very low exposures.

Bottom line: If trying to conceive a child or during pregnancy, try to minimize exposure to plastics, pesticides, flame retardants, non-stick cookware, stain-proofing (in fabric and rugs), fragrances and scented products (including air fresheners and dryer sheets), and food stored in cans and plastic containers. Avoid triclosan, anti-odor, antibacterial, anti-germ products and clothing. Avoid parabens (in lotions, etc). Read labels. Glass and stainless steel is perfectly fine. Use unscented or fragrance free products as much as possible.

From Medical Xpress: Chemicals in consumer products during early pregnancy related to lower IQ   ...continue reading "Pregnancy, Endocrine Disrupting Chemicals, and Lower IQ"

Published on Leave a comment on Are You Drinking Tiny Plastic Particles In Your Tea?

Did you know that many tea bags contain plastic or are made totally from plastic? And that tiny pieces of plastic (microplastics) from these teabags are released into the hot water when brewing tea? Canadian researchers found that a single plastic teabag releases about 11.6 billion microplastic and 3.1 billion nanoplastic particles into the water during normal tea brewing. And no one knows what this is doing to us long term, but it is doubtful that ingesting billions of tiny plastic particles in each cup of tea is beneficial to health. View it as an "unknown risk".

The researchers point out that water is frequently at or above 95 degrees C (203 degrees F) when brewing tea, and that "food grade"plastics degrade or leach toxic substances when heated above 40 degrees C (104 degrees F). They tested 4 different commercial teabags in 95 degree C water for 5 minutes. Note: Boiling water is 100 degrees C or 212 degrees Fahrenheit. On the other hand, the researchers noted that few plastic particles were released into room temperature water.

Microplastics are particles ranging from 100 nm to 5mm in size, while nanoparticles are particles ≤ 100 nm in size. The researchers found that many, many more plastic particles were released into the water from the teabags than what has been reported in other foods (e.g. salt or bottled water).

There is another reason to also avoid plastic teabags - if the plastic contains phthalates (endocrine disruptors), it will leach them into the hot water. Which, of course, we are then drinking.

What to do? Just stick with the traditional paper teabags. But you'll have to do research to find one that has zero added plastic. Some bags may appear to be paper, but plastic may be coating the paper, or in the glue sealing sides of the bag. Or drink tea made from loose leaf tea. By the way, any company that advertises its tea bags as "silky", "silken sachets", or "mesh" is using plastic tea bags. There is no silk used. Also, assume that any company that won't tell you if it uses plastic in the tea bags, has plastic in the teabags.

Nowadays many foods come in plastic pouches that are meant to be heated - keep in mind that they probably all leach plastic particles into the food or liquid. If the idea of ingesting multitudes of tiny plastic particles concerns you - avoid heating foods in plastic pouches or containers. Instead, transfer into a glass, stainless steel or iron container for heating.

From Science Daily: Plastic teabags release microscopic particles into tea  ...continue reading "Are You Drinking Tiny Plastic Particles In Your Tea?"

Published on Leave a comment on Why Are We Still Using These Dangerous Substances In Consumer Products?

More bad news about the toxic class of chemicals called PFAS chemicals, which are used in a wide variety of consumer products, such as Teflon non-stick cookware and Scotchgard. The problem is that the chemicals don't stay in the products, but leach out (migrate out) and spread further - even into us. Unfortunately these chemicals persist in the environment. Earlier studies had already detected PFAS  (per- and polyfluoroalkyl substances) chemicals in water, soil, some foods, and in the bodies of almost all Americans. Now some recent research studies and the efforts of investigative journalists have uncovered more disturbing findings about the spread of these chemicals in the environment, in foods, and us.

The site Intercept has done a series of investigative reports highlighting these new findings about PFAS chemicals For example, these chemicals are found in fertilizers that contain sewage sludge (or biosolids) that farmers use on their farms. Farmers have been been doing this for decades. And it's in milk from dairy farms that spread this compost (fertilizer) made from sewage sludge on their fields. Of course! What is spread on the fields gets into food and which humans then ingest. The chemicals are also found in breastmilk from women in every country that has been studied.

Environmental Working Group (EWG) also has a series of articles on these chemicals, including the results of a recent FDA study of foods. The FDA found PFAS in many foods, including meat, seafood, dairy products, sweet potatoes, pineapples, leafy greens, and chocolate cake with icing. But the FDA has not publicly disclosed the results. Why not? Especially since the EPA has already said that "dietary exposure" (what we eat) is a main way that people get these chemicals into their bodies.

Why should we be concerned? PFAS chemicals are called  by some as "persistant chemicals" because of their persistence in the environment and humans. PFAS chemicals are linked to all sorts of serious health risks, including reproductive harm (e.g.poorer semen quality), cancers, lowered sex and growth hormones in children, immune effects,  thyroid disease, liver and kidney damage, and high cholesterol.

PFAS chemicals (such as PFOA, PFOS, PFBS) are used in a wide variety of consumer products because they have stain, water, and grease repellent properties. They are used in nonstick cookware, in food packaging (especially the paper wrappers and cardboard containers), stain-resistant carpets, furniture, floor waxes, textiles, water-proof and stain-resistant clothing (such as Gore-tex fabric), and performance gear. Remember Teflon? That's one. Some have been banned, phased out of use because of their dangers, but the replacements appear to be just as bad. The chemicals migrate out of food packaging into food, or can be released into the air and dust from carpets and upholstery treated with stain-resistant coatings.

I want to point out that sewage sludge (also called biosolids), are found in many commonly available fertilizers, such as Milorganite fertilizer.  It's not just farmers who've been using the stuff for years. Note that organic fertilizers and organic farmers can NOT use sewage sludge (biosolids). It turns out that even compostable food containers contain PFAS chemicals that leach out. Yikes!

What can you do to lower exposure to PFCs? These are chemicals that are hard to totally avoid, but one can lower exposure to them. And some have been phased out. The good news is that research shows that after a while levels in blood and breast milk should drop. What to do?? First of all, don't use non-stick pots and pans, and definitely not older Teflon ones. Use stainless steel or cast iron instead. Avoid the use of non-stick smooth dental floss made with a "non-stick" coating such as Oral-B Glide dental floss (use plain waxed or unwaxed floss instead). Try to not eat prepared foods in coated containers frequently. Avoid Scotchgard or other stain-proofing or stain-resistant treatments on upholstered furniture or rugs. Avoid water-proof treated fabric. It's also best to avoid drinking PFAS-contaminated water (which may be hard to do in places such as NJ where so much of the water supply is contaminated by PFAS chemicals).

From the Intercept - TOXIC PFAS CHEMICALS FOUND IN MAINE FARMS FERTILIZED WITH SEWAGE SLUDGE ...continue reading "Why Are We Still Using These Dangerous Substances In Consumer Products?"