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Category: endocrine disruptors

Published on Leave a comment on Why Are We Still Using These Dangerous Substances In Consumer Products?

More bad news about the toxic class of chemicals called PFAS chemicals, which are used in a wide variety of consumer products, such as Teflon non-stick cookware and Scotchgard. The problem is that the chemicals don't stay in the products, but leach out (migrate out) and spread further - even into us. Unfortunately these chemicals persist in the environment. Earlier studies had already detected PFAS  (per- and polyfluoroalkyl substances) chemicals in water, soil, some foods, and in the bodies of almost all Americans. Now some recent research studies and the efforts of investigative journalists have uncovered more disturbing findings about the spread of these chemicals in the environment, in foods, and us.

The site Intercept has done a series of investigative reports highlighting these new findings about PFAS chemicals For example, these chemicals are found in fertilizers that contain sewage sludge (or biosolids) that farmers use on their farms. Farmers have been been doing this for decades. And it's in milk from dairy farms that spread this compost (fertilizer) made from sewage sludge on their fields. Of course! What is spread on the fields gets into food and which humans then ingest. The chemicals are also found in breastmilk from women in every country that has been studied.

Environmental Working Group (EWG) also has a series of articles on these chemicals, including the results of a recent FDA study of foods. The FDA found PFAS in many foods, including meat, seafood, dairy products, sweet potatoes, pineapples, leafy greens, and chocolate cake with icing. But the FDA has not publicly disclosed the results. Why not? Especially since the EPA has already said that "dietary exposure" (what we eat) is a main way that people get these chemicals into their bodies.

Why should we be concerned? PFAS chemicals are called  by some as "persistant chemicals" because of their persistence in the environment and humans. PFAS chemicals are linked to all sorts of serious health risks, including reproductive harm (e.g.poorer semen quality), cancers, lowered sex and growth hormones in children, immune effects,  thyroid disease, liver and kidney damage, and high cholesterol.

PFAS chemicals (such as PFOA, PFOS, PFBS) are used in a wide variety of consumer products because they have stain, water, and grease repellent properties. They are used in nonstick cookware, in food packaging (especially the paper wrappers and cardboard containers), stain-resistant carpets, furniture, floor waxes, textiles, water-proof and stain-resistant clothing (such as Gore-tex fabric), and performance gear. Remember Teflon? That's one. Some have been banned, phased out of use because of their dangers, but the replacements appear to be just as bad. The chemicals migrate out of food packaging into food, or can be released into the air and dust from carpets and upholstery treated with stain-resistant coatings.

I want to point out that sewage sludge (also called biosolids), are found in many commonly available fertilizers, such as Milorganite fertilizer.  It's not just farmers who've been using the stuff for years. Note that organic fertilizers and organic farmers can NOT use sewage sludge (biosolids). It turns out that even compostable food containers contain PFAS chemicals that leach out. Yikes!

What can you do to lower exposure to PFCs? These are chemicals that are hard to totally avoid, but one can lower exposure to them. And some have been phased out. The good news is that research shows that after a while levels in blood and breast milk should drop. What to do?? First of all, don't use non-stick pots and pans, and definitely not older Teflon ones. Use stainless steel or cast iron instead. Avoid the use of non-stick smooth dental floss made with a "non-stick" coating such as Oral-B Glide dental floss (use plain waxed or unwaxed floss instead). Try to not eat prepared foods in coated containers frequently. Avoid Scotchgard or other stain-proofing or stain-resistant treatments on upholstered furniture or rugs. Avoid water-proof treated fabric. It's also best to avoid drinking PFAS-contaminated water (which may be hard to do in places such as NJ where so much of the water supply is contaminated by PFAS chemicals).

From the Intercept - TOXIC PFAS CHEMICALS FOUND IN MAINE FARMS FERTILIZED WITH SEWAGE SLUDGE ...continue reading "Why Are We Still Using These Dangerous Substances In Consumer Products?"

Published on Leave a comment on Male Fertility Is Plunging In Switzerland

Two years ago scientists reported an alarming and steep decline in sperm counts in men from Western industrialized countries over the last 40 years. Both sperm count and sperm concentration declined 50 to 60% in this period in men in North America, Europe, Australia, and New Zealand. Especially concerning was that there was no evidence of this year by year decline leveling off.

What does this mean? As these declines continue, more and more men will have sperm counts below the point at which they can reproduce. Instead they will be infertile or "sub-fertile" (fertilization is unlikely). According to the World Health Organization (WHO), a sperm count of below 15 million per ml makes a man subfertile. However, also of concern is the threshold level associated with a "decreased monthly probability of conception", which is 40 million/ml - which means conception will take significantly longer (due to impaired ability to fertilize an egg).

A recent Univ. of Geneva study looked at semen quality of 2523 young men (aged 18 to 22 years old) who were being drafted into the military in Switzerland. They found that average sperm quality and sperm concentration of the men, who were from all regions of Switzerland, was among the lowest in Europe (along with Germany, Denmark, and Norway).

In Europe, median sperm count ranges from 41 to 67 million per milliliter (ml), depending on the country. The researchers found that the group of Swiss men had a median sperm count of 48 million per ml. And 17 percent of the men had sperm counts below 15 million per ml (thus subfertile). By the way, countries with lower sperm counts and quality, have higher rates of testicular cancer - they go hand in hand.

Also, in a quarter of the Swiss men studied, less than 40 percent of sperm cells were motile (moved normally), and 43 percent of men had less than 4 percent normally formed sperm. Overall, only 38 percent of Swiss men had healthy sperm - that is, with concentration, motility, and morphology (shape, form) that met the WHO’s criteria for healthy sperm.

Why is this happening? The researchers found that of the men with very low sperm concentration, more of their mothers smoked during the pregnancy, which means there could be changes during embryonic development. Also, while this study did not discuss this, many other researchers say that sperm health is "the canary in the mine" for male health - evidence of harm to men from environmental and lifestyle influences. 

These Western developed countries are awash in chemicals and plastics, also with endocrine disruptors (hormone disruptors) in our foods, our personal care products, in products all around us - and so studies find these chemicals in all of us (in varying degrees). Same with flame retardants, pesticides, "scented" products. Exposure to all sorts of environmental pollutants - whether in air, water, soil, our food - such as high levels of aluminum. All of these can have an effect on sperm counts and reproductive health. You can't totally avoid these chemicals, but you can try to lower your amounts of exposure (some tips to lower exposures).

From Medical Xpress: Poor semen quality in Switzerland   ...continue reading "Male Fertility Is Plunging In Switzerland"

Published on Leave a comment on Sunscreen Chemicals Enter the Bloodstream

A recent study found that within hours of applying sunscreen, the chemicals in the sunscreen appear in the person's blood - and at levels high enough to be of concern. Of course the chemicals enter the body! Why is anyone surprised? Generally, assume that what you put or get on your skin enters your body - lotions, pesticides, etc.

The small study was conducted by the Center for Drug Evaluation and Research, which is a part of the US Food and Drug Administration (FDA). Commonly available sunscreens (2 different sprays, a lotion, and a cream) were applied on 24 volunteers according to directions. Within hours the four sunscreen ingredients being studied (avobenzone, oxybenzone, ecamsule and octocrylene) had entered the bloodstream at levels high enough to cause concern.  They also found that the blood concentration of three of the ingredients continued to rise as daily use continued and then remained in the body for at least 24 hours after sunscreen use ended.

The four chemicals studied are among a dozen chemicals that the FDA recently said needed to be researched by manufacturers before they could be considered "generally regarded as safe and effective." Especially worrisome is oxybenzone, which is in 85% of chemically based sunscreens - and has also been found in breast milk, amniotic fluid, urine, and blood. It is an endocrine disruptor, and linked to various health problems. With these chemicals, the more one uses, the more gets into the body - and people may apply sunscreen several times a day. They may also be found in personal care products and cosmetics. But unfortunately, as with so many chemicals that we are exposed to - long-term effects of frequent or chronic exposure are unknown.

The Environmental Working Group (EWG) rates sunscreen chemicals and is an excellent resource in finding safe sunscreens, as well as those that should be avoided. The EWG has a page discussing the problems with these chemicals, including that they are endocrine disruptors. They also have a page on nanoparticles (typically zinc and titanium dioxide), which are also used in sunscreens.ided. The EWG has a page discussing the problems with these chemicals, including that they are endocrine disruptors. They also have a page on nanoparticles (typically zinc and titanium dioxide), which are also used in sunscreens.

...continue reading "Sunscreen Chemicals Enter the Bloodstream"

Published on Leave a comment on What’s Getting Into You From Vinyl Flooring?

Many of us have concerns over the fact that people are constantly exposed to endocrine disruptors (chemicals that disrupt hormonal systems) in many common household and personal products. Even the vinyl flooring found in many homes  contains phthalates, which are endocrine disrupting chemicals. In the past year several studies have looked at vinyl flooring in homes and whether the chemicals in the flooring outgas into the air and then get into people living in the homes. The answer is YES - the chemicals in vinyl flooring do get into people living there, and they can be measured in urine (in the breakdown products of phthalates called metabolites).

Since research shows that endocrine disrupting chemicals have health effects, then the question is: Do chronic low levels do anything to people? Especially worrisome is, are they having an effect on the developing fetus when pregnant women are exposed to them and they get into the body? The following 2 studies looked at flooring, but keep in mind that we are exposed to phthalates in many, many products - e.g., plastic shower curtains, plastic food containers, some personal care products, household products. The problem is that the pthalates migrate out of the plastic products - they don't stay in the product. In the case of vinyl flooring - one can say that there are phthalate emissions from the flooring! And of course it gets into household dust.

Numerous studies found that phthalates (the phthalate metabolites) are routinely found in people of all ages - throughout the world. It can be measured in our blood (serum) and in our urine. Studies find them in breastmilk and also in amniotic fluid. Research finds associations associations between exposure to several phthalates and various effects on human health, including reproductive effects.

The following are two complementary studies. Study 1 looked at vinyl flooring (called PVC flooring in the article) in homes (in the kitchen and bedrooms), and found that phthalates get into pregnant women, and can be measured in the urine. Study 2 (from Duke University), found that chemicals children are exposed to in the home from vinyl flooring and the sofa (flame-retardants) can be measured in their blood and urine. The researchers took all sorts of samples from homes and children over a 3 year period and found evidence in the children of exposure to phthalates, organophosphate esters, brominated flame retardants, parabens, phenols, antibacterial agents and perfluoroalkyl and polyfluoroalkyl substances (PFAS).

So we have proof that these chemicals are getting into us. We can't avoid them totally, but can lower our exposure levels - look for upholstered furniture without flame retardants (read the label!), and don't install vinyl flooring (wood and tile floors are OK).  ...continue reading "What’s Getting Into You From Vinyl Flooring?"

Published on Leave a comment on Common Chemical Has Negative Effects On Sperm of Both Humans and Dogs

To the alarm of many, male fertility (sperm quality and sperm counts) has been rapidly declining over the past few decades. Researchers suspect that it's due to our exposure to chemicals in the environment, especially to endocrine disrupting chemicals - of which there are many, and to which we are exposed to daily. A recent study found that detrimental effects occur in the sperm of both humans and dogs when exposed to the common plastic softener DEHP and the persistent industrial chemical polychlorinated biphenyl 153 (PCB153). The researchers suggest this is because dogs live in households with humans and thus are exposed to the same environmental contaminants.

DEHP (diethylhexyl phthalate) is an endocrine disruptor (interferes with hormone systems) that is found in plastic materials in many household and personal items - for example, in carpets, vinyl flooring, some upholstery, rainwear, wires, some plastic toys, fragrances and air fresheners, some PVC pipes, some food packaging, medical tubing, plastic shower curtains. The problem is that it slowly leaches out of the products and into the air and household dust, it leaches out of packaging into foods (which we then ingest), and it can also be absorbed through direct skin contact. Bottom line: try to avoid DEHP by avoiding plastics known as polyvinyl chloride (PVC) or vinyl as much as possible. (One can't totally avoid them, but can reduce exposure to them.)

From Science Daily: Chemical pollutants in the home degrade fertility in both men and dogs, study finds

New research by scientists at the University of Nottingham suggests that environmental contaminants found in the home and diet have the same adverse effects on male fertility in both humans and in domestic dogs.  ...continue reading "Common Chemical Has Negative Effects On Sperm of Both Humans and Dogs"

Published on Leave a comment on Avoid Using Products With the Antimicrobial Triclosan

Many health professionals have warned for years that the antibacterial triclosan should be avoided. Triclosan is found in a large variety of personal and consumer products labeled "antibacterial" or "antimicrobial". Now a recent study gives another reason to avoid triclosan - it makes UTI (urinary tract infection) bacteria MORE resistant to antibiotics.

Scientists have been warning about triclosan (and related triclocarbon) for a while, and have asked that their use be restricted due to risks to human health, to wildlife, and its accumulation in water, land, wildlife, and humans. Not only do they persist in the environment, they are also a source of toxic and carcinogenic compounds including dioxins, chloroform, and chlorinated anilines. They are endocrine disruptors that bioaccumulate (build-up) in humans and wildlife. They are toxic to aquatic and other organisms, yet they are found in the majority of people and freshwater streams. In other words, the chemicals are all around us and in us!

More than 2000 personal and consumer products, as well as building materials, contain triclosan and triclocarban. For example, they are found in soaps, toothpastes, detergents, clothing, toys, carpets, plastics, kitchen items, and paints. According to the FDA, which is responsible for regulation of foods, drugs, cosmetics, medical devices, and similar products, there is no evidence that antibacterial soaps are more effective than nonantibacterial soap and water.

What should one do? Read labels and avoid products containing triclosan and other antimicrobials, and products labeled anti-odor, antibacterial, anti-germ, or containing Microban. No, you don't need antibacterial or anti-odor socks or cutting boards! See earlier posts on this topic (here, here, and here).

From Science Daily: Chemical added to consumer products impairs response to antibiotic treatment

Grocery store aisles are stocked with products that promise to kill bacteria. People snap up those items to protect themselves from the germs that make them sick. However, new research from Washington University in St. Louis finds that a chemical that is supposed to kill bacteria is actually making them stronger and more capable of surviving antibiotic treatment.  ...continue reading "Avoid Using Products With the Antimicrobial Triclosan"

Published on Leave a comment on Breast Cancer and Endocrine Disruptors

Some good news for women and breast cancer. We are all exposed to endocrine disruptors  around us - such as in personal care items, some household items, some medical devices and medications, plastic raincoats, and vinyl flooring. Phthalates, which are endocrine disruptors, are used as plasticizers in many of these products. We can lower our exposure to phthalates, but can't totally eliminate it. So a big question is: Is exposure to phthalates linked to breast cancer?

Animal and laboratory studies suggest that a number of phthalates have carcinogenic effects (cancer causing), but several retrospective studies of women had mixed results regarding whether higher phthalate levels are associated with breast cancer or not. But now a large study (the Women's Health Initiative) that followed postmenopausal women for 2 decades has found that phthalate levels are not associated with an increased risk of breast cancer.

The 1257 women (average age 62 1/2 years at the start) in the study gave either 2 or 3 urine samples (once a year) during the first 2 or 3 years of the study, and the urine was analyzed for a number of phthalates. Then the women were followed for 19 years. The researchers found some "suggestive associations", but nothing significant. Whew... We can breathe sigh of relief.

However, there are some real problems with the study. While it does not look likely that phthalates have a large effect, smaller associations are possible, which the researchers discuss.

1) One big problem is that phthalates are rapidly metabolized and excreted from the body, so that the levels can vary tremendously from one point in time to another. (Half of phthalate metabolites are excreted in urine within 12 to 24 hours of exposure.) And the researchers did find that "phthalate biomarker concentrations exhibited high within-person variability over a 3 year period".  More urine samples should have been taken from the women - not just one a year for 2 or 3 years. This study did not look at who routinely got exposed to high levels of phthalates and who wasn't. Half of phthalate metabolites are excreted in urine within 12 to 24 hours of exposure. Just having a week with lots of fast food could raise phthalate levels (the chemicals leach in from the packaging). See why only one measurement a year is inadequate?

2) Another big problem is that most of the postmenopausal women - whether with breast cancer or not, were using hormone therapy - in the past or during the study. As the researchers point out: "Because phthalates are far less estrogenic than hormone therapy formulations, it is possible that hormone therapy use may mask any true effect of phthalate exposure on breast cancer risk." 3) And the last big issue to think about is that this study did not look at early life exposures to phthalates, such as during puberty when the breasts are developing. Other studies suggest that exposure to endocrine disrupting chemicals are important during critical periods of life, especially earlier in life (e.g. adolescence). Looking just at phthalate exposure of postmenopausal women may be too late.

According to studies and the CDC, almost everyone in the United States is exposed to phthalates in varying degrees, especially by eating and drinking food and liquid that has come in contact with containers and products containing the chemicals, and by inhaling indoor air that has phthalates in the dust. Adult women tend to have higher exposure to certain phthalates (it's measured in the urine) that are used in soaps, body washes, shampoos, cosmetics, and similar personal care products.  ...continue reading "Breast Cancer and Endocrine Disruptors"

Published on Leave a comment on New Book Warning Us About Endocrine Disruptors

The following is a really nice article about endocrine disruptors (chemicals that can interfere with the body's hormonal system). Journalist Hillary Brueck writes about where they are found (all around us!), some of the many negative health effects, and about NYU physician and researcher Dr. Leonardo Trasande and his new book: "Sicker, Fatter, Poorer: The Urgent Threat of Hormone-Disrupting Chemicals to Our Health and Future ... and What We Can Do About It." Also, some things we can do to lower our exposure to endocrine disruptors.

By the way, once again Europe is ahead of the US in dealing with this problem. Excerpts from Business Insider: A toxic-chemicals expert is sounding the alarm about 4 cancer-linked chemicals that could be making us sicker and fatter

Through the course of a single day, your hands, mouth, and body come in contact with countless pieces of paper, plastic, fabric, and furniture. You probably don't think about the chemicals these substances might harbor, or consider that they have a drug-like effect on health. But some do. They can make metabolisms slow down, subtly lower IQs, contribute to ADHD in children, and mess with sperm counts in men.

They're called "endocrine disruptors," and they're around us all the time. The chemicals change how our bodies work by shifting the way hormones operate, according to Leo Trasande, a pediatrician and public-health researcher at NYU Langone Health. "Hormones are the basic signaling molecules in our body that take on so many actions for practically every organ system," Trasande told Business Insider. "And endocrine disruptors are synthetic chemicals that scramble those signals, contributing to disease and disability."

In his new book, "Sicker, Fatter, Poorer: The Urgent Threat of Hormone-Disrupting Chemicals to Our Health and Future ... and What We Can Do About It," Trasande lays out the four big categories of endocrine disruptors he's most concerned about, based on evidence from scientific studies and observations in his patients. They are: Bisphenols, like BPA, which are often found in the linings of aluminum-canned food and drinks and on cash-register receipts. Brominated flame retardants that are in some carpets, furniture, and clothing. Synthetic pesticides on food. "Plasticizer chemicals" called phthalates that show up in plastic food packaging, lotions, and cosmetics.  ...continue reading "New Book Warning Us About Endocrine Disruptors"

Published on Leave a comment on Health Stories to Follow in 2019

New research is published every day, but only some studies are big research stories or game-changers. The following are what I consider some of the most memorable studies of 2018 – some in a good way, but some of the others have left me with a sense of horror. I think there will be follow-up research, so keep an eye out for more on these important topics.

Are we heading toward a time in the not so distant future when all men are infertile? (Due to exposure to all the endocrine disruptors around us.) Will All Men Eventually Be Infertile? This was posted September 5, 2018.

Researchers are now seriously investigating and finding evidence that microbes may be causing Alzheimer’s disease. This approach is rapidly finding support in the medical field, and may lead to possible ways to treat or prevent the disease. Possible Herpes Virus Link to Alzheimer’s Disease was posted July 13, 2018, and Herpes Viruses and Alzheimer's Disease on  June 22, 2018.

Type 2 Diabetes May Be Reversed With Weight Loss was posted August 10, 2018. This study and an earlier similar study from 2016 found that losing over 30 pounds over a short period can reverse type 2 diabetes - 46% in the 2018 study and 60% (in people who had it less than 10 years) in the earlier study.

More and more evidence is accumulating that certain diets are anti-inflammatory. Especially beneficial are diets rich in fruits, vegetables, seeds, nuts, legumes (beans), and whole grains - which also have a lot of fiber. This is exciting research because chronic low-grade inflammation is linked to a number of chronic diseases (heart disease, cancer, etc.). Fruits, Vegetables, and Whole Grains Lower Inflammation – posted August 1, 2018.

[Related to this last topic is one of the most eye-opening studies I have ever read on how what one eats has a quick effect on gut microbes and health of the gut (including inflammation of the colon): Changing Diet Has Big Effect On Colon Cancer Risk – posted April 28, 2015.]

Published on Leave a comment on Some Types of Dental Floss Should Be Avoided

Dental floss coated with a "non-stick coating" has long been a concern of mine. Do the Teflon-like chemicals get into the person when a person is flossing teeth? These chemical compounds (called per- and polyfluoroalkyl substances or PFASs) are linked to health problems (e.g. kidney and testicular cancer, semen quality, thyroid disease, immune system effects, and lowered sex and growth hormones in children) - so you want to avoid them if possible. Well, it turns out these chemicals are shed into the person's mouth when flossing and can be measured in a person's blood. Bottom line: avoid non-stick smooth dental floss such as Oral-B Glide dental floss (or when the dental floss label brags that it is similar to Glide dental floss). Use plain waxed or unwaxed floss instead.

Per- and polyfluoroalkyl substances (PFASs) are a group of chemicals used in a wide variety of consumer products because they have water- and grease-resistant properties. They are used in nonstick cookware, in food packaging (especially the paper wrappers and cardboard containers) , stain-resistant carpets, furniture, floor waxes, textiles, water-proof and stain-resistant clothing (such as Gore-tex fabric), and performance gear. How do they get into us? Some ways: the chemicals can migrate out of food packaging into food, or can be released into the air and dust from carpets and upholstery treated with stain-resistant coatings. PFASs have been detected in water, soil, and in the bodies of almost all Americans!

This study (and others)  found that higher levels of  these chemicals in the body occur with the following: frequent consumption of prepared food in coated cardboard containers, having stain-resistant carpets or furniture, using Oral-B Glide dental floss, and living in a city served by a PFAS-contaminated water supply. It may not be possible to totally avoid all PFASs, but one can lower exposure to them (for example, don't have stain-resistant carpets in the house or apartment, and try to eat less fast-food). From Medical Xpress:

Dental flossing and other behaviors linked with higher levels of toxic chemicals in the body        ...continue reading "Some Types of Dental Floss Should Be Avoided"