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Category: diabetes

Published on Leave a comment on Study Found Losing Weight Reversed Type 2 Diabetes

scale, weightType 2 diabetes is a huge problem in the US. Studies have long suggested that losing weight can help a person reduce or even stop having to use diabetes medication, and even reverse the diabetes. A recent study also found that type 2 diabetes in overweight individuals can be reversed by losing weight.

The good news is that the weight loss doesn't have to be huge - it can be as little as 8% of body weight (e.g., 16 lbs in a 200 pound person). Losing 8% of their body weight improved glycemic control because there was an improvement in their insulin responsiveness. By the way, all the participants in the study had a "sedentary lifestyle" and none exercised.

From Medical Xpress: Can type 2 diabetes be reversed? Experts say 'yes'

More than 36 million Americans have type 2 diabetes, a condition primarily attributed to the body's cells not responding to insulin properly, leading to high blood sugar levels. Due to the concomitant increase in the prevalence of obesity, type 2 diabetes is rising across the U.S. and around the world.

Insulin resistance drives type 2 diabetes, Shulman explains. "If you reverse insulin resistance, you reverse type 2 diabetes," he said. In a landmark study, Shulman and Kitt Petersen, MD, professor of medicine (endocrinology), showed that modest weight reduction—even as little as 10%—does just that. The study is published in the journal Diabetes. ...continue reading "Study Found Losing Weight Reversed Type 2 Diabetes"

Published on Leave a comment on Diet and Risk of Developing Dementia

One message keeps being supported by research: Eat a diet rich in fruits, vegetables, seeds, nuts, whole grains, legumes, and olive oil. A reason is because this diet is anti-inflammatory. And it turns out that inflammation is at the root of many diseases, including heart disease. And dementia.

A recent study that followed more than 84,342 older adults (60 years or older at the start of the study) found that those who ate an anti-inflammatory diet had a 21% lower chance of developing dementia. They also had larger gray matter volume in the brain, and smaller white matter lesions or spots in the brain (white matter hyperintensity volume). All of the adults had cardiometabolic diseases (e.g., heart disease, diabetes, stroke) at the start of the study.

Other studies have already confirmed that eating an anti-inflammatory diet (e.g., Mediterranean diet) is linked to lower risk of diabetes, heart disease, lower dementia risk, better cognitive function, and better brain aging (as measured by MRI scans).

From Medical Xpress: Anti-inflammatory diet could lower your odds for dementia

Eating a healthy diet that dampens inflammation in the body could lower your odds for dementia, especially if you already have heart risk factors, a new Swedish study shows. ...continue reading "Diet and Risk of Developing Dementia"

Published on Leave a comment on A Mediterranean Style Diet Feeds Beneficial Gut Bacteria

The incidence of both intestinal bowel diseases (IBD) and colorectal cancer is rapidly increasing in developed countries (e.g., US, Canada, Europe). There are many theories over why this is occurring, with most researchers thinking a person's diet plays a role. A big suspect in promoting IBD and colorectal cancer is the Western diet, which has lots of ultra-processed foods and is also low in fiber.

A recent large study looked at 6 major diets and how they impact the gut microbiome. The six dietary patterns were: Western diet, Mediterranean diet, high-fiber diet, plant-based diet, high protein diet, and ketogenic diet.

And surprise, surprise - eating a Western diet resulted in having an increase in gut bacterial species linked to chronic inflammation, heart disease, colorectal cancer, IBD, and diabetes. The Mediterranean style diet had an increase in bacterial species linked to a lower risk of cardiovascular disease, IBD, and type 2 diabetes. In fact, all 6 diets had distinct bacterial profiles in the gut.

Bottom line: The foods a person eats can either feed and nourish beneficial bacteria or harmful bacteria (linked to cancer and IBD). Best for health is a Mediterranean style diet (lots of fruits, vegetables, whole grains, legumes, seeds, nuts), and avoiding ultra-processed foods. You are what you eat!

From Medical Xpress: Western diets pose greater risk of cancer and inflammatory bowel disease, study finds

Western diets pose a greater risk of inflammatory bowel disease (IBD) and colorectal cancer, according to a milestone review of what people eat around the world. ...continue reading "A Mediterranean Style Diet Feeds Beneficial Gut Bacteria"

Published on Leave a comment on Denialism and Cover-up At Manufacturer Of Forever Chemicals
3M Company Credit: Wikipedia

Forever chemicals are in the news all the time now. A very interesting and well-researched article was recently published by the investigative journalism site ProPublica about Kris Hansen, a chemistry PhD who worked at 3M company. Initially, as part of her job in 1997, she documented that forever chemicals (PFOS, PFAS) were showing up in everyone's blood - both workers at the company, as well as people outside the company. Animals also. But then her work was suppressed, her bosses at 3M convinced her the chemicals were safe, and she continued working there for years.

Also... she was sidelined by her bosses after her initial findings, her job became more limited at the company, and finally she moved to a different area of the company (medical devices). Yet for years she told her husband and herself that the chemicals were safe. Only in 2021, after watching a John Oliver segment on TV about forever chemicals, she finally googled PFOS. But she only left the company in 2022 (after 26 years) when her job was eliminated.

One interesting part to me was - How did she rationalize doing nothing and continue working there for decades? She knew it was appearing in everyone's blood, there was research (animal and human) available showing it caused harms, and yet.... she chose to believe what management was saying (it's safe), stayed silent, and basically buried her head in the sand. Didn't want to know...

Yes, I've seen this elsewhere - when interacting with people in higher level white collar jobs in the pesticide industry. Their salaries are good, their jobs depend on denialism and ignoring scientific research, and so they spout the industry line of "it's safe"..."nothing is proven". So it continues...

A few excerpts from ProPublica: Toxic Gaslighting: How 3M Executives Convinced a Scientist the Forever Chemicals She Found in Human Blood Were Safe

The next morning, anxious to see the results, Hansen arrived at the lab before anyone else. For the first time since she had begun testing blood, some of the samples showed no trace of PFOS. She was so struck that she called her husband. There was nothing wrong with her equipment or methodology; PFOS, a man-made chemical produced by her employer, really was in human blood, practically everywhere. ...continue reading "Denialism and Cover-up At Manufacturer Of Forever Chemicals"

Published on Leave a comment on Over 30 Health Harms Associated With Ultra-Processed Foods

The studies finding health harms from ultra-processed foods keep coming. Ultra-processed foods are food products manufactured with all sorts of ingredients (additives) not normally found in our kitchens. Examples of such ingredients are: emulsifiers, carrageenan, mono- and diglycerides, soy lecithin, polysorbate, cellulose, colors, titanium dioxide, high fructose corn syrup, hydrogenated oils, dextrose, whey protein, nitrates, flavors (artificial and natural), colors, etc.

A large review of studies (none of which were affiliated with companies producing ultra-processed foods) found that eating ultra-processed foods are linked to over 30 health harms. Some of the health harms had especially strong associations: early death, death from heart disease (cardiovascular disease), type 2 diabetes, adverse sleep outcomes, wheezing, and obesity. In general, the more ultra-processed foods one ate, the higher the risk for harms.

Bottom line: Read ingredient lists, and try to avoid ultra-processed foods. Even foods such as cereals can have one that is ultra-processed (a formulation of ingredients that result from industrial processes) next to one that only has natural real ingredients without any additives.

From Medical Xpress: Consistent evidence links ultra-processed food to over 30 damaging health outcomes

Consistent evidence shows that higher exposure to ultra-processed foods is associated with an increased risk of 32 damaging health outcomes including cancer, major heart and lung conditions, mental health disorders, and early death. ...continue reading "Over 30 Health Harms Associated With Ultra-Processed Foods"

Published on Leave a comment on A Five Day Fasting-Mimicking Diet Has Health Benefits

Another recent study found numerous health benefits in persons following an intermittent fasting-like diet for 3 months. It resulted in changes in blood and liver markers indicating a lower risk for several diseases (e.g., diabetes), and it reduced biological age 2.5 years.

Researchers found that following a diet that mimics fasting 5 days, then a normal diet 25 days for 3 monthly cycles improve a number of cardiometabolic risk factors such as reduced insulin resistance and other pre-diabetes markers. It also decreased abdominal fat and liver fat, and improved immune system functioning.

What did they eat during the 5 fasting-like days? They ate plant-based, low-calorie, and low-protein foods such as vegetable-based soups, energy bars, energy drinks, chip snacks, chamomile tea, and a supplement providing high levels of minerals, vitamins, and essential fatty acids. The foods were prepackaged and provided by an outside company to ensure the diet was followed.

But more importantly, the participants didn't really fast the 5 days - they just really cut back on calories, and ate plant-based foods. In other words, this type of diet is much easier to follow than a total fast, especially for several months. After the 5 days, the participants resumed eating their normal diet for the next 25 days.

From Medical Xpress: Fasting-like diet lowers risk factors for disease, reduces biological age in humans: Study

Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat in humans, resulting in a lower biological age, according to a new USC Leonard Davis School of Gerontology-led study. ...continue reading "A Five Day Fasting-Mimicking Diet Has Health Benefits"

Published on Leave a comment on Studies Find That Ice Cream Has Health Benefits

There is nothing so refreshing as some cold ice cream on a hot summer day. But rather than viewing it as a guilty pleasure, research actually finds that it has health benefits!

Studies find that ice cream eaters have a lower risk of developing type 2 diabetes. This is the same level of protection as eating yogurt.

What? Yup, studies found this health benefit, but it doesn't fit the prevailing dietary view of ice cream being an unhealthy food that should be avoided. So... the  researchers of the studies didn't discuss the findings, and instead the results were hidden away. In other words, a case of bias.

By the way, cheese has had the same kind of bias against it for years (all that fat!), but finally the research finding health benefits is being discussed in the media (Consumer Reports).

Excerpts from The Atlantic: NUTRITION SCIENCE’S MOST PREPOSTEROUS RESULT Studies show a mysterious health benefit to ice cream. Scientists don’t want to talk about it.

Back in 2018, a Harvard doctoral student named Andres Ardisson Korat was presenting his research on the relationship between dairy foods and chronic disease to his thesis committee. One of his studies had led him to an unusual conclusion: Among diabetics, eating half a cup of ice cream a day was associated with a lower risk of heart problems. Needless to say, the idea that a dessert loaded with saturated fat and sugar might actually be good for you raised some eyebrows at the nation’s most influential department of nutrition. ...continue reading "Studies Find That Ice Cream Has Health Benefits"

Published on Leave a comment on Plant-based Diets and Lower Risk Of Type 2 Diabetes

Some good news. A recent large study found that a healthy diet rich in plant-based foods can lower your risk of getting type 2 diabetes.

Researchers at the Harvard T.H. Chan School of Public Health found that a healthy diet rich in plant-based foods (fruits, vegetable, legumes, nuts, whole grains, coffee) resulted in plasma metabolite profiles that were associated with a lower risk of type 2 diabetes.

In other words, differences in the chemical make-up of foods means that what a person eats is reflected in their metabolite profile. The 200+ plasma metabolites include lipids, cholesterol, glycerides, phospholipids, fatty acids, inflammation, amino acids, and these give a metabolic profile.

Bottom line: A diet rich in plant-based foods is good for your health in many  ways, including lowering your risk of type 2 diabetes. One such example of a good way to eat (dietary pattern) is a Mediterranean style diet (rich in whole grains, legumes, fruits, vegetables, nuts, seeds, fish, and olive oil).

From Medical Xpress: New study reveals that healthy plant-based diets are associated with a lower risk of developing diabetes

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that the consumption of healthy plant-based foods, including fruits, vegetables, nuts, coffee, and legumes, is associated with a lower risk of developing type 2 diabetes (T2D) in generally healthy people and support their role in diabetes prevention.

...continue reading "Plant-based Diets and Lower Risk Of Type 2 Diabetes"

Published on Leave a comment on Two Studies Found Different Effects From Alcohol Consumption

The debate over health effects of light to moderate alcohol consumption continues. Today I read 2 studies with different conclusions about the effects of drinking small to moderate amounts of alcohol.

One study found a lower risk of type 2 diabetes when wine is drunk with meals, and the other study found that light to moderate drinking resulted in reductions in brain volume. One study health benefits, the other negative effects...

From Medical Xpress: Study finds drinking wine with meals was associated with lower risk of type 2 diabetes

An analysis of health data for nearly 312,400 current drinkers suggests consuming alcohol, most notably wine, with meals is associated with a lower risk of developing type 2 diabetes, according to preliminary research to be presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022.

Consuming alcohol with meals was associated with a 14% lower risk of type 2 diabetes compared to consuming alcohol without eating food.

From Medical Xpress: More alcohol, less brain: Study finds an association that begins with an average of just one drink a day

... But according to a new study, alcohol consumption even at levels most would consider modest—a few beers or glasses of wine a week—may also carry risks to the brain. An analysis of data from more than 36,000 adults, led by a team from the University of Pennsylvania, found that light-to-moderate alcohol consumption was associated with reductions in overall brain volume.

The link grew stronger the greater the level of alcohol consumption, the researchers showed. 

Published on Leave a comment on Dining Early Is Healthier Than Close to Bedtime

An easy-peasy way to lower your risk for type 2 diabetes may be to not eat late dinners. Research conducted in Spain found that eating a meal an hour before bedtime decreases insulin secretion, impairs and decreases glucose tolerance, and so increases type 2 diabetes risk.

Lead author Marta Garaulet, PhD said: "We found that late eating disturbed blood sugar control in the whole group." The study had 845 participants, none with diabetes, all living in Spain. Melatonin levels (which rise naturally in the 2 hours before bedtime) were involved - so researchers say don't eat a meal then. Those with a certain gene variant had more disturbed blood sugar control than those without the gene.

Bottom line: Don't eat a meal in the 2 hours before bedtime. 

From Medscape: Eating Dinner Late Ups Diabetes Risk; Melatonin Involved

Eating dinner close to bedtime when endogenous melatonin levels are high is associated with decreased insulin secretion and decreased glucose tolerance, which increase the risk of type 2 diabetes. ...continue reading "Dining Early Is Healthier Than Close to Bedtime"