New noteworthy research links commonly used household pyrethroid pesticides to attention deficit hyperactive disorder (ADHD) in children and young teens, especially boys. Ome drawback was that the results were based on a single urine sample.Since pyrethroids are non-persistent and rapidly metabolized, then looking at numerous samples over time would have provided a more accurate assessment of typical long-term exposure. Given how many households use pyrethroid pesticides and that there are seasonal variations in pesticide use, then it wouldn't be surprising if there are times when pyrethroid exposure is higher and so the link to ADHD may even be stronger than seen in this original study.From Medical Xpress:
A new study links a commonly used household pesticide with attention deficit hyperactivity disorder (ADHD) in children and young teens.The study found an association between pyrethroid pesticide exposure and ADHD, particularly in terms of hyperactivity and impulsivity, rather than inattentiveness. The association was stronger in boys than in girls.
Due to concerns about adverse health consequences, the United States Environmental Protection Agency banned the two most commonly used organophosphate (organic compounds containing phosphorus) pesticides from residential use in 2000-2001. The ban led to the increased use of pyrethroid pesticides, which are now the most commonly used pesticides for residential pest control and public health purposes. They also are used increasingly in agriculture.
Pyrethroids have often been considered a safer choice because they are not as acutely toxic as the banned organophosphates. Animal studies, on the other hand, suggested a heightened vulnerability to the effects of pyrethroid exposure on hyperactivity, impulsivity and abnormalities in the dopamine system in male mice. Dopamine is a neurochemical in the brain thought to be involved in many activities, including those that govern ADHD.
The researchers studied data on 687 children between the ages of 8 and 15. The data came from the 2000-2001 National Health and Nutrition Examination Survey (NHANES),...included a diagnostic interview of children's ADHD symptoms and pyrethroid pesticide biomarkers. Pesticide exposure measurements were collected in a random sample of the urine of half the 8-11 year olds and a third of the 12-15 year olds. ADHD was determined by meeting criteria on the Diagnosic Interview Schedule for Children,...
Boys with detectable urinary 3-PBA, a biomarker of exposure to pyrethroids, were three times as likely to have ADHD compared with those without detectable 3-PBA. Hyperactivity and impulsivity increased by 50 percent for every 10-fold increase in 3-PBA levels in boys. Biomarkers were not associated with increased odds of ADHD diagnosis or symptoms in girls.