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Lasting benefits from lifestyle changes (Mediterranean diet and exercise). From Science Daily:

Mediterranean diets have lasting health benefits

The health benefits of switching to a Mediterranean style diet and upping the amount of time spent exercising for a period of just eight weeks can still be seen a year after stopping the regime, a new study has shown.

The research by Sheffield Hallam University and the University of Lincoln in the UK revealed that the diet and exercise combination leads to improved blood flow in cells in the inner lining of the blood vessels -- called the endothelial cells -- a full 12 months after completing participation in the intervention programme.

Endothelial cells line the interior of the entire vascular system of the human body -- from the large arteries to the smallest capillaries -- and improvements in their function could reduce the risk of people developing cardiovascular disease, the study said.

Researchers believe the long-term health benefits observed after such a short intervention could be due to molecular changes associated with the Mediterranean diet. Traditional Mediterranean cuisine is based on olive oil, fruit, vegetables and salad, fish, legumes, whole grain foods, wine and limited consumption of red meat.

The study focused on healthy people over the age of 50. Participants were originally assessed over an eight-week period.One group was encouraged to eat more vegetables, fruit, olive oil, tree nuts and fresh oily fish, as well as take up a moderate exercise regime, while the other just took up exercise alone.

The results showed more health improvements in the Mediterranean diet group than the exercise only group, which one year later, were still evident despite the lifestyle changes implemented during the study no longer being carefully followed.

Once again research shows problems with physical inactivity: this time heart disease risk in women. From Science Daily:

From age 30 onwards, inactivity has greatest impact on women's lifetime heart disease risk

From the age of 30 onwards, physical inactivity exerts a greater impact on a woman's lifetime risk of developing heart disease than the other well-known risk factors, suggests research published online in the British Journal of Sports Medicine. This includes overweight. the findings show, prompting the researchers to suggest that greater effort needs to be made to promote exercise.

The researchers wanted to quantify the changing contribution made to a woman's likelihood of developing heart disease across her lifetime for each of the known top four risk factors in Australia: excess weight (high BMI); smoking; high blood pressure; and physical inactivity. Together, these four risk factors account for over half the global prevalence of heart disease, which remains the leading cause of death in high income countries.

They based their calculations on estimates of the prevalence of the four risk factors among 32,154 participants in the Australian Longitudinal Study on Women's Health, which has been tracking the long term health of women born in 1921-6, 1946-51, and 1973-8, since 1996.

Combining the prevalence and relative risk data, the researchers found that up to the age of 30, smoking was the most important contributor to heart disease, with a PAR of 59%. But from age 30 until the late 80s, low physical activity levels were responsible for higher levels of population risk than any of the other risk factors.

The researchers estimate that if every woman between the ages of 30 and 90 were able to reach the recommended weekly exercise quota -- 150 minutes of at least moderate intensity physical activity -- then the lives of more than 2000 middle aged and older women could be saved each year in Australia alone.

More studies showing health benefits of moving and exercise. From Science Daily:

Dangers of ... sitting? Regardless of exercise, too much sedentary time is linked to major disability after 60

If you're 60 and older, every additional hour a day you spend sitting is linked to doubling the risk of being disabled -- regardless of how much moderate exercise you get, reports a new Northwestern Medicine study.

The study is the first to show sedentary behavior is its own risk factor for disability, separate from lack of moderate vigorous physical activity. In fact, sedentary behavior is almost as strong a risk factor for disability as lack of moderate exercise.

If there are two 65-year-old women, one sedentary for 12 hours a day and another sedentary for 13 hours a day, the second one is 50 percent more likely to be disabled, the study found.

"This is the first time we've shown sedentary behavior was related to increased disability regardless of the amount of moderate exercise," said Dorothy Dunlop, professor of medicine at Northwestern University Feinberg School of Medicine and lead author of the study. "Being sedentary is not just a synonym for inadequate physical activity."

Disability affects more than 56 million Americans. It's defined by limitations in being able to do basic activities such as eating, dressing or bathing oneself, getting in and out of bed and walking across a room. Disability increases the risk of hospitalization and institutionalization and is a leading source of health care costs, accounting for $1 in $4 spent.

The study focused on a sample of 2,286 adults aged 60 and older from the National Health and Nutrition Examination Survey. It compared people in similar health with the same amount of moderate vigorous activity. Moderate activity is walking briskly, as if you are late to an appointment.

The participants wore accelerometers from 2002 to 2005 to measure their sedentary time and moderate vigorous physical activity. The accelerometer monitoring is significant because it is objective.

From Science Daily:

Exercise may slow progression of retinal degeneration

Moderate aerobic exercise helps to preserve the structure and function of nerve cells in the retina after damage, according to an animal study appearing February 12 in The Journal of Neuroscience. The findings suggest exercise may be able to slow the progression of retinal degenerative diseases.

Age-related macular degeneration, one of the leading causes of blindness in the elderly, is caused by the death of light-sensing nerve cells in the retina called photoreceptors. Although several studies in animals and humans point to the protective effects of exercise in neurodegenerative diseases or injury, less is known about how exercise affects vision.

This is the first report of simple exercise having a direct effect on retinal health and vision," Pardue said. "This research may one day lead to tailored exercise regimens or combination therapies in treatments of blinding diseases."