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Author: Sima

Published on Leave a comment on Forever Chemicals Can Enter and Accumulate In the Brain

The toxic chemicals PFAS, commonly referred to as "forever chemicals" (due to their buildup and persistence in people and the environment) are in the news again. Once again, it's bad news. This time, researchers found that PFAS chemicals travel through the blood, and enter and accumulate in the human brain.

And not just the original PFAS chemicals (e.g., used in Teflon, Scotchgard), but even their replacements accumulate in the brain.

PFAS (Per- and polyfluoroalkyl substances) are called forever chemicals due to their buildup and persistence in people and the environment. They are in all of us at varying levels, and they have harmful health effects. Effects include cancer, reproductive harm (e.g., poorer semen quality), birth defects, lowered sex and growth hormones in children, thyroid disease, immune effects, and liver and kidney damage. They are endocrine disruptors.

The chemical industry would have you think that the newer PFAS chemicals that replace the older ones are "safer", but guess what? They're not. They're very similar chemically, so it shouldn't be surprising that they don't appear to be safer.

Bottom line: You can't totally avoid PFAS chemicals, but you can lower your exposure to them. If possible, avoid products that are water and stain proof or leak-proof, especially if children will be using the product. Don't use nonstick cookware, stain resistant carpeting and fabrics, clothing treated to be water-proof, and synthetic turf. PFAS don't have to be mentioned on labels, so it's buyer beware.

From Environmental Health News: PFAS can enter and accumulate in the brain, study confirms

A new study published in Environment International examines the ability of PFAS - a class of hazardous chemicals with known neurotoxic effects - to bypass the body’s protective barriers and enter into brain tissue. ...continue reading "Forever Chemicals Can Enter and Accumulate In the Brain"

Published on Leave a comment on The Skin Microbiome Is Different In Persons With Rosacea
Severe rosacea Credit: Wikipedia

A recent study confirmed that in the skin condition called rosacea, the skin microbiome is out of whack (dysbiosis). Of course. The study also confirmed that treatment with a topical ivermectin cream helps with the inflamed red skin rashes on the face and lowers the number of Demodex mites found on the skin.

Demodex mite Credit: Wikipedia

But while the cream improved symptoms in 44% of the patients, it didn't correct the skin dysbiosis. In rosacea, there is a big increase of Demodex mites (compared to normal levels) at the site of the red rashes or lesions. After the topical ivermectin cream treatment, the number of mites decreased in 88% of the rosacea group to more normal levels. [Yes, we all have Demodex mites living on our skin.]

However, other bacterial species are still different in the rosacea group compared to healthy persons without rosacea. The researchers found Cutibacterium species are predominant in healthy persons without rosacea, but are not found in persons when they have rosacea inflammation. Instead Staphylococcus species take over (just like in atopic dermatitis).

The skin microbiome is the community of bacteria, viruses, fungi that live on our skin. Rosacea is an inflammatory skin condition that typically affects the face resulting in redness, pimples, swelling, and dilated blood vessels. It frequently begins with flushing (redness) of the face in symmetrical patches, and it may or may not progress.

Excerpts from the medical site Medscape: Topical Ivermectin Study Sheds Light on Dysbiosis in Rosacea

Topical ivermectin has significant clinical efficacy and decreases the density of Demodex mites found in the skin of people with rosacea, but cutaneous dysbiosis remains, according to a report presented at the recent European Academy of Dermatology and Venereology (EADV) 2023 Congress. ...continue reading "The Skin Microbiome Is Different In Persons With Rosacea"

Published on Leave a comment on Problems With Gut Microbiome Tests Available to Consumers
Oral microbiome Credit: Wikipedia

People have questions about the direct to consumer (DTC) gut microbiome tests that are now available from at least 31 companies. What do the results mean and can we believe them?  Well... according to a recent article in the medical site Medscape, the tests may be appealing to the consumer, but right now they don't mean anything at all.

This is because the tests are both unreliable and unregulated. Results of microbes found in the stool will vary from day to day, and from test to test. The same stool samples sent to different companies or even to the same company come back with different results. Generally the tests are offered by companies that want to sell you something - their supplements or other products in order to "improve your gut health."

However, there is no evidence backing up their claims. The tests are also not consistent - some do genetic sequencing, but others are just culture or a microscopic analysis (which find only a few of the microbes in the microbiome). Researchers stress that standardization of these tests is needed.

Yes, the gut microbiome has a tremendous effect on health and disease, and microbiome therapies definitely have potential. But right now it's buyer beware!

Excerpts from Medscape: Are Direct-to-Consumer Microbiome Tests Clinically Useful?

Companies selling gut microbiome tests directly to consumers offer up a variety of claims to promote their products.

"We analyze the trillions of microbes in your gut microflora and craft a unique formula for your unique gut needs," one says. "Get actionable dietary, supplement, and lifestyle recommendations from our microbiome experts based on your results, tailored to mom and baby's biomarkers.…Any family member like dads or siblings are welcome too," says another. ...continue reading "Problems With Gut Microbiome Tests Available to Consumers"

Published on Leave a comment on Climate Scientists Are Very Worried About Our Future

The world is heating up quickly and climate scientists are very worried and scared about what's in our future. A recent survey conducted by The Guardian finds that climate scientists are very pessimistic about our ability to limit future temperature increases.

By the way, this past April was the 11th straight month of global record-breaking heat, and it looks like this trend will continue. Most of the scientists surveyed felt that we will blow past the internationally agreed 2.7 degrees F and will hit at least a 4.5 degrees F increase in this century. Almost half thought there would be a 5.4 degrees F increase.

This uncontrolled temperature increase will result in catastrophic changes for the world. Famines, mass migrations, heatwaves, wildfires, extreme storms! It's on us, especially our governments, to take action. Now!

Excerpts from The Guardian: World’s top climate scientists expect global heating to blast past 1.5C target

Hundreds of the world’s leading climate scientists expect global temperatures to rise to at least 2.5C (4.5F) above preindustrial levels this century, blasting past internationally agreed targets and causing catastrophic consequences for humanity and the planet, an exclusive Guardian survey has revealed. ...continue reading "Climate Scientists Are Very Worried About Our Future"

Published on Leave a comment on The EPA Reverses Course and Now Proposes Banning Toxic Pesticide

Update to the toxic pesticide acephate story of last week. Well, well, well.... Due to the big outcry after ProPublica's story exposing EPA's recent decision to relax standards and so allow much more of the toxic pesticide acephate in our food, the officials at the EPA changed their minds and now propose banning it! 

Acephate is an insect killer commonly used on celery, lettuce, cauliflower, tomatoes, peppers, and other fruits and vegetables, and residues stay on produce that we eat. It also contaminates drinking water. (It's used on non-organic crops, but it's not allowed to be used on organic crops.)

Propublica's story broke on April 24, 2024, and immediately afterwards there was outrage over the EPA's relaxing of the pesticide standards decision. This is because the FDA was totally ignoring years of scientific and medical research showing harms to humans, and only accepting and believing what the pesticide industry told them. It even ignored its own scientists and advisory groups.

Acephate is a pesticide known to be so harmful that it was BANNED in Europe more than 20 years ago, yet allowed in the US. A major reason: harmful effects on the developing brains of fetuses and children, and linked to autism, hyperactivity, and reduced scores on intelligence tests. In 2023, the CDC said that autism spectrum disorder rates have now increased to 1 out of every  36 births.

Now we wait and see: Will the FDA (once again) cave to industry or actually do what they are supposed to do - protect consumers? 

ProPublica is a non-profit investigative journalism site. The following are excerpts from their May 1, 2024 story on the FDA reversal. From ProPublica: EPA Proposes Ban on Pesticide Widely Used on Fruits and Vegetables

The Environmental Protection Agency unveiled a proposal this week to ban a controversial pesticide that is widely used on celery, tomatoes and other fruits and vegetables. ...continue reading "The EPA Reverses Course and Now Proposes Banning Toxic Pesticide"

Published on Leave a comment on Has Deer Chronic Wasting Disease Occurred In Humans?

Well, it finally might have occurred. The always fatal neurologic disease known as chronic wasting disease (CWD),  which occurs in deer, elk, and moose, and is slowly spreading throughout the US and Canada, may have finally made the jump from deer to humans. This is very worrisome.

CWD is a prion disease similar to "mad cow disease" (bovine spongiform encephalopathy) in cattle and Creutzfeldt-Jakob's disease in humans. There is no vaccine, treatment, or cure for the disease.

In the recently published study, two friends, who hunted and consumed venison from an area known to have chronic wasting disease in the deer population - both died from Creutzfeldt-Jakob disease (CJD) in 2022. Doctors think this is might be a case of "cross-species prion transmission".

So far CWD has been detected in 33 states and several Canadian provinces, and so far nothing has been found to eliminate or slow down the spread of the disease. High heat, disinfection, radiation - these don't kill the CWD prions.

How is it spread? Scientists believe CWD prions spread between animals through body fluids (e.g., feces, saliva, blood, or urine), either through direct contact or indirectly through environmental contamination of soil, food or water. Once introduced into an area or farm, the CWD prion (protein) is contagious within deer and elk populations and spreads.

Once CWD gets into the soil, it stays there for years, and so animals can contract it even after infected deer and elk have died. Recent research found that plants uptake the prions, where it remains infectious.

From Medical Xpress: Consumption of contaminated venison suspected in cases of deer hunters with prion disease

A small team of medical workers and researchers in the U.S. has published a case study of two men, both deer hunters, who developed a rare prion disease. In their study, published in the journal Neurology, the group describes the symptoms of the two patients and how they died.

...continue reading "Has Deer Chronic Wasting Disease Occurred In Humans?"

Published on Leave a comment on The EPA Proposes Relaxing Standards For A Toxic Pesticide

Once again the EPA is about to let us down - by not protecting us (the consumers) and giving in to big business. Against the advice of scientists and scientific advisory panels, the EPA is about to really relax standards for the toxic pesticide acephate.

This pesticide is an insecticide (kills insects) used on food crops, such as celery, lettuce, peppers, and tomatoes. So when you eat non-organic produce, you will also be ingesting the pesticide. But... studies find it is linked to neurological harms (e.g., autism, reduced scores on intelligence tests, hyperactivity). It also causes harms to bees and other pollinators, fish, and other mammals.

How could this happen? The EPA is only relying on industry studies (notorious for being biased) and ignoring independent studies that find harms. The EPA is proposing allowing 10 times more on foods  than is now allowed. Meanwhile, the European Union (EU) banned acephate 20 years ago!

The EPA also proposed relaxing standards for a similar pesticide - malathion. Nope, nope, nope - for all the same reasons .

Excerpts from the investigative news site ProPublica on April 24, 2024: 10 Times as Much of This Toxic Pesticide Could End Up on Your Tomatoes and Celery Under a New EPA Proposal

When you bite into a piece of celery, there’s a fair chance that it will be coated with a thin film of a toxic pesticide called acephate.

The bug killer — also used on tomatoes, cranberries, Brussels sprouts and other fruits and vegetables — belongs to a class of compounds linked to autism, hyperactivity and reduced scores on intelligence tests in children. ...continue reading "The EPA Proposes Relaxing Standards For A Toxic Pesticide"

Published on Leave a comment on Welcome To Global Weirding

There's a new word that describes all the weird weather we've been having recently. It's global weirding. It describes the weird weather extremes that we've been experiencing - for example, the extreme heat in Arizona last summer (more than a month of over 110 degrees F), extreme wildfires (Canada last year), extreme torrential rains.

All sorts of weather records are being broken each year. This weird and extreme weather is occurring because our climate is changing. Thomas Friedman described global weirding years ago. He wrote in the NY Times:

"Avoid the term “global warming.” I prefer the term “global weirding,” because that is what actually happens as global temperatures rise and the climate changes. The weather gets weird. The hots are expected to get hotter, the wets wetter, the dries drier and the most violent storms more numerous."

From Discover: As Weather Extremes Increase in 2023, Global Weirding Becomes a Better Term

While temperatures in Phoenix soared above 110 degrees Fahrenheit for a record-shattering 31 straight days in July, people began turning up in emergency rooms with third-degree burns they’d suffered after falling — their skin seared by blistering hot pavement. Although not unprecedented, burn specialists said the number and severity of injuries were much higher than ever before. ...continue reading "Welcome To Global Weirding"