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A large recent study found that commonly used erectile dysfunction drugs (e.g. Viagra, Cialis, Levitra, and Stendra) are associated with an increased risk for 3 types of vision problems: serious retinal detachment (SRD), retinal vascular occlusion (RVO), and ischemic optic neuropathy (ION).

Keep in mind that these are rare vison problems and the risk of developing these problems was elevated in regular users of erectile dysfunction (ED) medications. These ED drugs are phosphodiesterase type 5 inhibitors (PDE5Is). Those who developed these eye problems were also more likely to have hypertension, diabetes, coronary artery disease, and sleep apnea.

Bottom line: Regular users of erectile dysfunction medications should contact their eye care provider if they develop unusual eye symptoms.

From Medical Xpress: US insurance claims show strong link between erectile dysfunction medications and vision problems

The risk of developing one of three serious eye conditions increases by 85 percent for regular users of common erectile dysfunction (ED) medications such as Viagra, Cialis, Levitra and Stendra, new UBC research has found.

Two of the three conditions had previously been linked to ED medications only by anecdotal case studies. Those links are now confirmed for the first time by a large, epidemiological study, published today in JAMA Ophthalmology.  ...continue reading "Erectile Dysfunction Medications and Increased Risk of Some Eye Problems"

Covid-19 infections are linked to many long-term health problems, but now a surprising one - an increased risk for erectile dysfunction in sexually active men. University of Rome researchers found that the risk of developing erectile dysfunction (ED) increased six-fold after a COVID-19 infection. They also found that a person who already has erectile dysfunction is at five times higher risk for a COVID-19 infection.

They thought that erectile dysfunction after COVID-19 could be either a short or long-term effect  - meaning it might or might not go away over time.

Why would a coronavirus infection lead to erectile dysfunction? Evidence is finding that even "silent" asymptomatic COVID-19 infections may have an effect on small blood vessels so that there is endothelial dysfunction, which is impaired functioning of the inner lining of blood vessels. This means that arteries and arterioles are unable to dilate fully, and so blood supply to the penis can be blocked or narrowed.

Erectile dysfunction (ED) has been often considered a sign (a hallmark) of endothelial dysfunction. Higher rates of erectile dysfunction occur among men suffering from hypertension, obesity, diabetes, and heart disease.

The University of Rome researchers summed it up as get vaccinated or "Mask up to keep it up."

A related finding: Last year a study (conducted in China) that autopsied 12 persons who had died of COVID-19 found that they had damage in the testicles - with inflammation, fluid accumulation, and reduced numbers of Leydig cells (which normally produce testosterone).

Excerpts from Medscape: Risk for Erectile Dysfunction Sixfold Higher in Men With COVID-19

COVID-19 increases the risk of developing erectile dysfunction (ED) by nearly sixfold, according to data from the first study to investigate the association between ED and COVID-19 in young men in a real-life setting. ...continue reading "COVID-19 Infection Linked to Increased Risk of Erectile Dysfunction"