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Tag: vaccinations

Published on Leave a comment on High-Dose Flu Vaccines Lower the Risk of Developing Dementia
Human brain Credit: Wikipedia

The risk of developing dementia increases as a person ages. According to the National Institute of Health (NIH) the risk of dementia was 4% by the time a person is 75, and 20% by age 85, and even higher after 85 years of age. Thus the interest in ways to prevent the onset of dementia, including Alzheimer's disease.

One way to lower the risk of Alzheimer's disease is getting vaccinated, including the shingles and flu vaccines, after the age of 60. A recent study found that getting vaccinated with high dose flu vaccines in adults 65 years and older (instead of standard dose) reduces the odds of developing Alzheimer's disease even more.

A possible reason for the protective effect of the flu vaccine, especially the high-dose vaccine, is that vaccination strengthens immune defenses and reduces inflammation. Inflammation is thought to play a role in the development of Alzheimer's disease.

Excerpts from CIDRAP: High-dose flu vaccine tied to lower Alzheimer’s risk in older adults

Receiving a high-dose flu vaccine is associated with a significantly lower risk of Alzheimer’s disease than a standard-dose vaccine in adults aged 65 and older, according to a large observational study published in Neurology. The findings add to a growing body of evidence linking vaccination, and possibly immune system activity, to reduced dementia risk. ...continue reading "High-Dose Flu Vaccines Lower the Risk of Developing Dementia"

Published on Leave a comment on Study Finds Link Between Viruses and Alzheimer’s Disease

For a while now it has become clear to some scientists that the prevailing view of Alzheimer's disease (buildup in the brain of 2 substances: amyloid and tau) isn't correct. Instead, some researchers feel that there is growing evidence that viruses are implicated as a cause of Alzheimer's and other neurodegenerative diseases (e.g., vascular dementia, ALS, Parkinson's disease, multiple sclerosis).

A recent study linked 22 viruses to the development of Alzheimer's disease and other neurodegenerative diseases (e.g., vascular dementia, ALS, Parkinson's disease, multiple sclerosis) within 15 years. The strongest association was for viral encephalitis and later developing Alzheimer’s disease. Influenza with pneumonia was associated with 5 neurodegenerative diseases.

The researchers also found a link between infection with Epstein Barr and later developing multiple sclerosis (this confirmed other recent research).

Other studies find that vaccinations (influenza, pneumonia, shingles) are associated with lower rates of Alzheimer's disease. This has also been found with antivirals (e.g., for herpes simplex).

From Science Alert: A Study of 500,000 Medical Records Links Viruses to Alzheimer's Again And Again

A study of around 500,000 medical records suggested that severe viral infections like encephalitis and pneumonia increase the risk of neurodegenerative diseases like Parkinson's and Alzheimer's. ...continue reading "Study Finds Link Between Viruses and Alzheimer’s Disease"

Published on Leave a comment on Routine Vaccines Associated With A Reduced Risk of Developing Alzheimer’s Disease

Great news! A recent study found that older adults who get routine vaccinations have a  lower risk of developing Alzheimer's disease and related dementias. Other studies looking at adults over the age of 60  and routine vaccinations (flu, pneumonia) have had similar findings.

The vaccinations that were looked at in this study were: the shingles (herpes zoster) vaccine, pneumococcal vaccine, and tetanus-diphtheria vaccine. Each of the vaccines lowered the risk of getting AD - the tetanus-diphtheria (Tdap/Td) by 30%, the shingles vaccine by 25%, and the pneumococcal vaccine by 27%. The adults were at least 65 years of age at the start of the study.

Why would vaccines be protective? There  are multiple theories, including that infection may play a role in the development of Alzheimer's disease (AD), and vaccines reduce the risk for infections. Or that vaccines may activate the immune system in such a way that alters the risk for developing AD.

Bottom line: In persons over the age of 60, getting routine adult vaccinations (including the flu vaccine) may lower the risk of developing AD. So simple!

From Medical Xpress: Several vaccines associated with reduced risk of Alzheimer's disease in adults 65 and older

Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research from UTHealth Houston. ...continue reading "Routine Vaccines Associated With A Reduced Risk of Developing Alzheimer’s Disease"