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Great news! A recent study found that older adults who get routine vaccinations have a  lower risk of developing Alzheimer's disease and related dementias. Other studies looking at adults over the age of 60  and routine vaccinations (flu, pneumonia) have had similar findings.

The vaccinations that were looked at in this study were: the shingles (herpes zoster) vaccine, pneumococcal vaccine, and tetanus-diphtheria vaccine. Each of the vaccines lowered the risk of getting AD - the tetanus-diphtheria (Tdap/Td) by 30%, the shingles vaccine by 25%, and the pneumococcal vaccine by 27%. The adults were at least 65 years of age at the start of the study.

Why would vaccines be protective? There  are multiple theories, including that infection may play a role in the development of Alzheimer's disease (AD), and vaccines reduce the risk for infections. Or that vaccines may activate the immune system in such a way that alters the risk for developing AD.

Bottom line: In persons over the age of 60, getting routine adult vaccinations (including the flu vaccine) may lower the risk of developing AD. So simple!

From Medical Xpress: Several vaccines associated with reduced risk of Alzheimer's disease in adults 65 and older

Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research from UTHealth Houston. ...continue reading "Routine Vaccines Associated With A Reduced Risk of Developing Alzheimer’s Disease"

Breastfeeding
Credit: Wikimedia Commons/ Anton Nosik

Another new micronutrient has been discovered in breast milk. This is a sugar molecule called myo-inositol that promotes brain development in infants.

Researchers found that this sugar molecule is most abundant in human breastmilk early after birth when neuronal connections are rapidly forming in the infant brain. Three weeks after birth the levels found in breast milk slowly start to decrease.

This micronutrient was found in breast milk from women at all three study sites (Mexico City, Shanghai, and Cincinnati) - and at similar levels. The researchers stated that this could be one of the reasons why breast milk is so beneficial for a baby's brain development.

Interestingly, adults get myo-inositol from foods, with an adult eating a Western diet getting about 1 gram per day. It is also produced in the brain and other organs. It is especially abundant in fruits (e.g., cantaloupe and oranges), beans, grains, and nuts.

From Medical Xpress: Sugar molecule found in breast milk boosts infant brain development

Breast milk is not simply sustenance. It also is rich in micronutrients that are critical for healthy brain development in infants. ...continue reading "Breast Milk Contains Important Micronutrient For Brain Development"

No one should be surprised that chronic traumatic encephalopathy (CTE) has now been diagnosed (after death) in a female professional athlete - Heather Anderson. Years of repeated head trauma, whether from concussions or subconcussive hits, can eventually cause CTE. Head trauma, whether in males or females, occurs from body hits in football, rugby, heading the ball in soccer, and checking in ice hockey.

Heather Anderson was an Australian rules football player who started playing when she was 5, also played rugby, and eventually competed in the top women's Australian rules football league, retired at 23 after a shoulder injury, and committed suicide at 28. Both Australian rules football and rugby are contact sports. After death, her brain was examined and found to have the lesions characteristic of CTE.

CTE symptoms include memory loss, impaired judgement, confusion, aggression, depression, thinking about suicide, and eventually dementia. There is progressive degeneration of brain tissue in CTE, as well as build-up of the abnormal protein tau in the brain.

From NY Times: C.T.E. Found for First Time in Female Pro Athlete

For the first time, the degenerative brain disease chronic traumatic encephalopathy, or C.T.E., has been diagnosed in a female professional athlete, researchers reported. ...continue reading "CTE Found In Female Professional Athlete"

Holy moly! Our carbon dioxide levels are rising, really rising! Every year there is a new high, and this year is no exception.

According to NASA, in May at the Mauna Observatory in Hawaii the carbon dioxide measurement was 421 ppm. It's called the "global atmospheric carbon dioxide concentration". This week the reading at Mauna Launa Observatory is 423.96 ppm. It's going up! And yup, this is climate change.

From the NASA Global Climate Change page on Carbon Dioxide (go to the link to see the graphs, and prepare to be shocked).

Carbon Dioxide  LATEST MEASUREMENT:  May 2023     421 ppm

Key Takeaway: Carbon dioxide in the atmosphere warms the planet, causing climate change. Human activities have raised the atmosphere’s carbon dioxide content by 50% in less than 200 years.

Carbon dioxide (CO2) is an important heat-trapping gas, or greenhouse gas, that comes from the extraction and burning of fossil fuels (such as coal, oil, and natural gas), from wildfires, and from natural processes like volcanic eruptions.

Since the beginning of industrial times (in the 18th century), human activities have raised atmospheric CO2 by 50% – meaning the amount of CO2 is now 150% of its value in 1750. This is greater than what naturally happened at the end of the last ice age 20,000 years ago.

The animated map shows how global carbon dioxide has changed over time. Note how the map changes colors as the amount of CO2 rises from 365 parts per million (ppm) in 2002 to over 400 ppm currently. (“Parts per million” refers to the number of carbon dioxide molecules per million molecules of dry air.) These measurements are from the mid-troposphere, the layer of Earth's atmosphere that is 8 to 12 kilometers (about 5 to 7 miles) above the ground.

One big concern that needs to be addressed: What will high carbon dioxide levels do to our thinking processes? Over the years carbon dioxide levels have been rising, and are now at levels not experienced in several million years!

Think of a "stuffy room" where it is harder to think - this can already occur starting at about 600 ppm of CO2, and known to occur at 945 ppm and higher (in rooms with many people in them). While current CO2 levels are below that, we are faced with the possibility that if they keep rising we will get there eventually - and there will be no escape from the "stuffy room" feeling!

...continue reading "Carbon Dioxide Levels Are Higher Than Ever In the Atmosphere"

One fear people have is of developing problems with their memory in their later years, called age-related memory loss. A recent study finding a possible way to maintain memory in older adults is intriguing and offers hope. And best of all, it's fairly easy to do - just increase the intake of flavanol rich foods.

A large Columbia University study of adults over age 60 found that daily flavanol supplementation (cocoa extract with 500 mg flavanols) over a 3 year period improved the memory of persons whose diet was low in flavanol intake from foods, but not in persons with high intake of flavanols. The researchers suggest that a low flavanol diet is one of the drivers of age-related memory loss.

The researchers stated that flavanols only improved memory processes governed by the hippocampus, and did not improve memory mediated by other areas of the brain.

Flavanols are natural substances found in certain fruits and vegetables, especially berries, onions, kale, lettuce, tomatoes, apples, grapes, and cocoa. Flavanols are a type or class of flavonoids, all of which have health benefits. Eat a variety of plant foods (includes tea and wine) to ensure you're eating a variety of flavonoids.

Some other benefits of flavonoids: they are anti-inflammatory, anti-oxidative, have anti-mutagenic and anti-carcinogenic properties, lower heart disease death rates, and prevention of heart disease.

From Medical Xpress: Low-flavanol diet drives age-related memory loss, large study finds

A large-scale study led by researchers at Columbia and Brigham and Women's Hospital/Harvard is the first to establish that a diet low in flavanols—nutrients found in certain fruits and vegetables—drives age-related memory loss. ...continue reading "Eating A Diet Rich in Flavanols May Help With Memory"

For a while now it's known that exposure to pesticides is associated with developing Parkinson's Disease. But which pesticides? This is an important question because millions of pounds of pesticides are applied in the US each year. A recent study provides some answers.

The Harvard and UCLA Health researchers looked at 288 pesticides. They found that 53 pesticides were associated with Parkinson's disease, but 10 were directly toxic to dopaminergic neurons. Dopaminergic neurons are cells in the brain, and their degeneration and death play a key role in Parkinson's disease.

The 10 most toxic pesticides included four insecticides (dicofol, endosulfan, naled, propargite), three herbicides (diquat, endothall, trifluralin), and three fungicides (copper sulfate [basic and pentahydrate] and folpet). Some are commonly used even by homeowners, such as Preen (contains trifluralin) and Ortho Groundclear (contains diquat).

They also found that co-exposure to several pesticides (which typically happens) have a greater negative effect than just 1 pesticide.

Bottom line: There is much we don't know about pesticides, but studies are finding more health harms each year. Avoid using pesticides in your home, lawn, and garden if you can - especially unnecessary "cosmetic" lawn pesticides. Best and safest is to use nontoxic Integrated Pest Management (IPM) or organic.

Think of it this way: pesticides can give you cancer and damage your health, but clover and crabgrass can't.

From Science Daily: 10 pesticides toxic to neurons involved in Parkinson's

Researchers at UCLA Health and Harvard have identified 10 pesticides that significantly damaged neurons implicated in the development of Parkinson's disease, providing new clues about environmental toxins' role in the disease. ...continue reading "Pesticides Involved in the Development of Parkinson’s Disease"

A recent study may contribute to explaining why autism spectrum disorder (ASD) rates are rising so rapidly in the US. The CDC reports that 1 in 36 children have autism spectrum disorder as of 2020!! Researchers and physicians agree that things in the environment (e.g., pesticides) are playing a role in this increase.

Even though the study was conducted in mice, it examined the impact of pesticides called pyrethroids on neurological development. They found that even at low levels that humans are typically exposed to, there were neurological effects on mice who were exposed during pregnancy. Their behaviors were altered in a negative way, for example an increase in repetitive behaviors.

Pyrethroids are being used in increasing amounts in the US for all sorts of insect treatments, both inside and outside of homes. It's very frequently used against mosquitos. Studies find that 70 to 80% of the US population have pyrethroid breakdown products (metabolites) in the blood. This is because we are exposed to chronic low levels - whether in the air, in water, around our homes or workplace.

The researchers wrote in the published research that scientists are especially concerned with pyrethroid exposure because it has a harmful effect on fetal development in both humans and animals. Studies are finding links from pyrethroid exposure during pregnancy or infancy and developmental delays.

"Critically, evidence from recent epidemiology and longitudinal studies suggests that ambient prenatal exposure to pyrethroid pesticides poses a risk for autism, developmental delay, and neurodevelopmental disorders in general. Analysis of data from the CHARGE study showed a significant increase in risk for either ASD or developmental delay from exposure during pregnancy to pyrethroid pesticides being applied up to 1.5 km from the home. A regional study in New York showed an association between areas where aerial application of pyrethroid pesticides was used, and ASD and developmental delay prevalence in the area. Additionally, the presence of pyrethroid metabolites in blood or urine correlates with risk for ADHD in children."

Bottom line: Avoid using pyrethroids around the home and yard. Look into IPM (Integrated Pest Management) or organic and natural ways to deal with pests. Pyrethroids are also toxic to bees, and we need bees. Synthetic pyrethroids (which is what is commonly used) are not like natural extracts from the chrysanthemum flower, and don't let someone tell you they are.

Excerpts from Medical Xpress: Research links common insecticide to neurodevelopmental disorders

A new study from The University of Toledo suggests early exposure to a common class of insecticides called pyrethroids may increase the risk of autism and other developmental disorders, even at levels currently recognized as safe by federal regulators. ...continue reading "Pyrethroids and Autism Spectrum Disorder"

Child Credit: Wikipedia

The CDC reports that autism (autism spectrum disorder) rates are still increasing in the US, from 1 in 150 twenty years ago to 1 in 36 children in 2020. That's huge!

It's not just better screening and diagnosis. Rates are increasing so rapidly that researchers agree that there are environmental factors going on. But what are they?

The researchers of the report point out known factors (e.g., age of parents, multiple gestation birth, prematurity, genetics), but what is not discussed are all the chemical toxins in our environment that people are exposed to both prenatally and after birth (postnatally). Studies find that pregnant women are exposed to more harmful industrial chemicals nowadays than ever before.

For example, lead, heavy metals, and pesticides. People use pesticides in the home, on home exteriors, in their gardens and lawns, on pets, on crops, they're in foods we eat, in water we drink, even in rainfall (!). Millions of pounds are used each year in the US. Many of them have neurological effects.

This means that babies and young children are also exposed to more pesticides than ever before. The American Academy of Pediatrics has been warning about the dangers of pesticide exposure in children for years.

Excerpts from Futurity (site for research news from universities): United States autism rates hit new high

More children have been diagnosed with autism than at any time since monitoring began more than two decades ago, according to new federal studies. About 4% of 8-year-old boys and 1% of 8-year-old girls, in the United States have autism, according to the US Centers for Disease Control and Prevention (CDC). ...continue reading "Autism Spectrum Disorder Rates Hit New High"

Another important nutrient for brain health is magnesium. A recent study found that ingesting higher levels of magnesium from foods (dietary magnesium) is associated with better brain health and brain volume. Brains normally shrink a little with age, but ingesting higher levels of dietary magnesium resulted in less age-related shrinkage.

The researchers found that the effects were especially beneficial for postmenopausal women. It is important to note that all study participants had recommended or higher levels of magnesium intake from foods. No one had a magnesium deficiency. Recommended dietary allowances are 400–420 mg for men and 310–320 mg for women - but the results from this study suggest that ingesting even more from foods is better.

In other words, consider magnesium important for a healthy brain. Try to increase intake of magnesium rich foods. The researchers point out that recent studies suggest that dietary magnesium is associated with better cognitive function and may reduce the risk of dementia.

Foods rich on magnesium: pumpkin seeds, almonds, spinach, cashews, pumpkin seeds, chia seeds, peanuts, shredded wheat cereal, quinoa, soymilk, black beans, edamame, dark chocolate, bread, whole wheat, avocado, potato, nuts, bananas.

From Medical Xpress: A higher dose of magnesium each day keeps dementia at bay

More magnesium in our daily diet leads to better brain health as we age, according to scientists from the Neuroimaging and Brain Lab at The Australian National University (ANU). ...continue reading "Magnesium Is Important For Brain Health"

Another large study found that eating a Mediterranean diet is beneficial to health - specifically, that it is associated with a decreased risk for dementia. As much as 23% lower (compared to those who didn't eat a Mediterranean style diet)! It didn't matter if a person had a genetic risk for dementia or not - diet was more important.

By the way, other studies also find that eating a Mediterranean style diet has benefits for the brain and body.

A Mediterranean style diet is one rich in fruits, vegetables, whole grains, legumes (beans, lentils), nuts, seeds, herbs, spices, and olive oil. Some lean meat, especially chicken, and fish. This way of eating is high in fiber (good for health!). Try to avoid processed meats, highly processed foods, fast food, and hydrogenated oils. Eat less meat in general.

From Science Daily: Mediterranean diet associated with decreased risk of dementia

Experts at Newcastle University found that individuals who ate a Mediterranean-like diet had up to 23% lower risk for dementia than those who did not. ...continue reading "A Mediterranean Style Diet Is Associated With A Lower Dementia Risk"