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Researchers in Canada found that sunlight (or UVB light) on the skin changes the gut microbes (gut microbiome), especially in people with lower levels of vitamin D, that is, who are vitamin D deficient. UVB (Ultraviolet B light) exposure increased beneficial gut microbe diversity and richness in these people, as well as increasing their vitamin D levels. However, people who had been taking vitamin D supplements prior to the study, and who had sufficient vitamin D levels, did not have significant gut microbiome changes.

The researchers viewed the study results as evidence that there may be a skin-gut axis. As the researcher Vallance said: “It is likely that exposure to UVB light somehow alters the immune system in the skin initially, then more systemically, which in turn affects how favorable the intestinal environment is for the different bacteria,” suggested Vallance.

The researchers also thought that these study results (which was conducted in Vancouver, Canada, in healthy human volunteers) could help explain the protective effect of UVB light against inflammatory diseases such as multiple sclerosis (MS) or inflammatory bowel disease (IBD). And how did the researchers know what bacteria were in the gut in the study participants? They analyzed the feces with modern genetic sequencing methods. By the way, these results match what has been found in earlier studies in humans and mice.

Bottom line: Sunlight on the skin is beneficial to the gut microbiome, by increasing gut bacteria linked to health. In the study the increases in bacteria (after UVB light exposures) were in the Lachnospiraceae, Ruminococcus, and Clostridiaeae families. And nope, none of those are found in currently available probiotics. By the way, this study was conducted in winter in Canada, so the effects of UVB light were clearly seen in the healthy volunteers. This study supports getting some sunlight exposure (on the skin), and perhaps supplementing with vitamin D in the winter.

From Medical Xpress: Where the sun doesn't shine? Skin UV exposure reflected in poop  ...continue reading "Exposure To Sunlight Improves Gut Microbes and Vitamin D Levels"

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Researchers are starting to raise concerns about routine daily intake of probiotics for "gut health". Much is still unknown, but problems are starting to appear. A healthy gut contains hundreds of species (bacteria, fungi, viruses), and taking megadoses of a few species (a probiotic supplement) can overwhelm the normal gut microbial community. A healthy gut is one with a greater diversity of species, not just some species.

For example, one study found that daily probiotic ingestion can result in overgrowth of some bacterial species in the intestines, resulting in such symptoms as brain fogginess, bloating, and gas. Successful treatment was antibiotics and stopping the use of probiotics.   Another recent study found that after using antibiotics, those who took probiotics (thinking it would help microbial recolonization of the gut microbes) actually had slower recovery of the gut microbiome (microbial community).  The best recovery was in those who took nothing, no supplements at all, or those who received a fecal microbial transplant (where an entire microbial community is transplanted).

The evidence is showing that for gut microbial health, the best thing to do is eat a variety of real whole foods (and not highly processed foods) that have lots of fiber, such as whole grains, fruits, vegetables, seeds, nuts, and legumes (beans). In other words, feed the beneficial bacteria. A Mediterranean style diet is good.

A recent article in Medscape (the medical site) highlights these same concerns. [See below.] A study that looked at the gut microbiome of people who were about to undergo treatment for melanoma found that those who were taking probiotics actually had worse gut microbial diversity. [Remember, gut microbial diversity is considered an indicator of gut health.] And the cancer treatment (immunotherapy) did not work as well on them.

Bottom line: The evidence is showing that for gut microbial health, the best thing to do is eat a variety of real whole foods (and not highly processed foods) that have lots of fiber, such as whole grains, fruits, vegetables, seeds, nuts, and legumes (beans). In other words, feed the beneficial bacteria. A Mediterranean style diet is good. Don't take routine daily supplements or probiotics for  "gut health" - they won't help. Instead, if you want - only take probiotics for a short while for a specific symptom or problem.

Dr. Lorenzo Cohen wrote a piece for the Wall Street Journal laying out those same points. Excerpts from: Those Probiotics May Actually Be Hurting Your ‘Gut Health’  ...continue reading "Daily Use of Probiotics Can Hurt Gut Health"

The evidence is building, study by study, that we are all exposed to a mixture of hormone disrupting chemicals (endocrine disruptors) on a daily basis, and that these have serious health effects, including on the developing fetus during pregnancy. Researchers found that early prenatal exposure to a mixture of endocrine disrupting chemicals  was associated with lower levels of cognitive functioning (lower IQ scores) at age seven, particularly among boys.

Researchers in New York City and Sweden looked at the impact of 26 endocrine disrupting chemicals during pregnancy on 718 Swedish mother-child pairs. It appeared that the higher the exposure during pregnancy, the more of an effect at age 7. Especially harmful was the BPA replacement chemical BPF - this is because it is chemically related to BPA.

Endocrine disrupting chemicals (EDCs) include bisphenols (BPA and its replacement  chemicals, such as BPF - used in products called "BPA free"), phthalates (especially used in vinyl products), parabens, chemicals used in flame retardants and non-stick coatings,  and some pesticides (e.g. the commonly used chlorpyrifos).

Especially worrisome is that while scientists typically test chemicals one at a time to determine their safety, in the real world we are all exposed to mixtures of these chemicals in our food, consumer products (including personal care products and cosmetics), and environment. Some of these chemicals can cross the placenta during pregnancy and so have an effect on the developing the fetus, including brain and neurological development. Yes, some of these chemicals are only in the body for a short time, but during critical developmental  stages, the effects can be big - even at very low exposures.

Bottom line: If trying to conceive a child or during pregnancy, try to minimize exposure to plastics, pesticides, flame retardants, non-stick cookware, stain-proofing (in fabric and rugs), fragrances and scented products (including air fresheners and dryer sheets), and food stored in cans and plastic containers. Avoid triclosan, anti-odor, antibacterial, anti-germ products and clothing. Avoid parabens (in lotions, etc). Read labels. Glass and stainless steel is perfectly fine. Use unscented or fragrance free products as much as possible.

From Medical Xpress: Chemicals in consumer products during early pregnancy related to lower IQ   ...continue reading "Pregnancy, Endocrine Disrupting Chemicals, and Lower IQ"

Food is all important for health. A recent study (that analyzed data from 10 large studies in the US, Europe, and Asia) found an association between high fiber intake from foods and also frequent eating of yogurt with a lower incidence of lung cancer. Persons with the highest yogurt and fiber consumption had a 33% reduced risk of lung cancer (when compared to the group who did not consume yogurt and consumed the least amount of fiber).

Think of it this way: The fiber in foods feeds the beneficial bacteria in the gut. High fiber foods that feed microbes in the gut are known as prebiotics. It is good to eat a variety of foods, because they provide a variety of fibers. High fiber foods are whole grains, fruits, vegetables, seed, nuts, and legumes (beans).

Gut microbes use fiber to generate short-chain fatty acids, and these are anti-inflammatory. Evidence suggests that the beneficial effects are not restricted to the gut, but reach organs throughout the body, including the lungs. The researchers suggest that both fiber and yogurt have anti-inflammatory effects, and the combination of fiber and yogurt is stronger against lung cancer than either alone. They also thought that the Lactobacillus and Bifidobacterium species in yogurt somehow help improve the gut microbial system.

From Medical Xpress:  High fiber, yogurt diet associated with lower lung cancer risk  ...continue reading "High Fiber Foods, Yogurt, and Lung Cancer"

Reading the following study, I thought to myself - OK, once again someone is testing a supplement, but generally studies find that supplements don't do as well as real, actual foods in whatever is being tested. In this case, a supplement containing lycopene, which is found in tomatoes, was tested by researchers in the UK to see if it would help with sperm quality in men. Other studies have found dietary lycopene to have health benefits (e.g. lower incidence of lethal prostate cancer), which is among the reasons the researchers focused on testing it for semen quality.

The study design was nice - with 60 young healthy men randomly assigned to one of 2 groups - the supplement group and the placebo group, and no one knew who was assigned to which group (double blind). They took either the lycopene supplement (14 mg/d of lactolycopene, equivalent to 2 kg of cooked tomatoes)  or a placebo for 12 weeks. They found changes in sperm quality after the 12 weeks, with significant improvement in the proportion of "fast progressive sperm" and normally shaped sperm (morphology). However, "motile sperm concentration" (the number of moving sperm) did not improve - and this is considered the main measure associated with chance of conception. So it is unknown how the 2 things that improved would affect fertility.

Bottom line: Studies find numerous health benefits from diets rich in fruits and vegetables, including tomatoes and other red foods, such as watermelon, papaya, and pink grapefruit. And yes - ketchup is a good source. Apparently more lycopene is bioavailable when tomatoes are cooked or processed, especially when cooked in oil (as compared to raw tomatoes). And when eating fruits and vegetables, try to eat as many that are organically grown, because eating fruits and vegetables with high levels of pesticide residues has a negative effect on sperm quality.

From Science Daily: Dietary supplement from tomatoes discovered to boost sperm quality  ...continue reading "Lycopene In Tomatoes and Sperm Quality"

Very depressing news about football. A study looking at those who played football long-term (as a career in adulthood) found that for every year of playing tackle football (lots of pounding and repeated head collisions), a person's risk of developing chronic traumatic encephalopathy (CTE) increases by 30%. The researchers from the Boston Univ. School of Medicine arrived at this conclusion after looking at 266 deceased former amateur and professional football players.

What was different about this study was that they compared football players who did not develop CTE with those who did - so the researchers thought it was representative of career football players.

The study results make total sense, but are horrifying because of all the children in the US growing up and playing tackle football from a young age. Other studies find brain changes from just playing some semesters in high school or college or before the age of 12.

From Futurity: CTE RISK GOES UP 30% FOR EACH YEAR OF PLAYING FOOTBALL  ...continue reading "Football May Not Be A Good Career Choice"

Once again a study finds health problems from supplements. This time, researchers found that several bodies of evidence (the long-running American Nurses' Study and two studies in Norway) found a higher risk of hip fracture in postmenopausal women who took high doses of both vitamin B6  and B12. Interestingly, B12 alone seemed to not be associated with problems. And only getting the vitamins from foods was totally fine.

Yes, taking supplements is highly popular, but many studies are finding adverse effects. As the researchers point out in the journal article: "Both insufficient and excess intakes of a nutrient may be harmful. According to randomized clinical trials (RCTs), high-dose vitamin supplementation may lead to unexpected adverse effects."

The researchers also point out that studies find that vitamin B supplementation has not had a preventive effect on cardiovascular diseases (heart disease) and cancer. Also, taking high doses of vitamin B12 and folic acid supplements has not shown a fracture-preventing effect in studies. And now this finding of a combination of high dose vitamin B-6 and B-12  is associated with an almost 50% higher risk of hip fracture in postmenopausal women. Uh-oh.

So instead of taking supplements, focus on a good diet with a wide variety of foods. Only take (high dose) supplements if there is a known deficiency, and not "just in case".

Excerpts from Medical Xpress:  Too much vitamin B can cause hip fracture  ...continue reading "High Dose Vitamin B Supplements and Hip Fractures"

Good news for women who really like to eat onions and garlic! A study conducted in Puerto Rico found that women who more frequently consumed garlic and onions, especially  "sofrito", had a lower risk of breast cancer. Both onions and garlic are an important part of the Puerto Rican diet, and sofrito is a raw onion and garlic based condiment or puree that is the base for many Puerto Rican dishes.

This study found that as consumption of garlic and onions increased, there was a decrease in the risk of breast cancer, which was true for women both before menopause or after menopause. There was evidence of a dose-response (the more eaten, the lower the risk). This association was especially strong for women consuming sofrito more than once a day - they had a 67% decrease in breast cancer risk compared to those who never ate sofrito.

The researchers point out that studies show that the more one eats of onions and garlic, the lower the risk of certain cancers, such as the lung, prostate, colon, and stomach. However, the evidence for whether it has a protective effect on breast cancer has been mixed, but with most studies finding a protective effect with frequent consumption of onions and garlic, especially raw onions and garlic. One study in Mexico found a 70% lower risk of breast cancer in those eating one slice of onion per day, compared to those eating less than one slice. The researchers also mentioned that studies find that cooking onions and garlic reduces their anticancer activity.

From Science Daily: Onion and garlic consumption may reduce breast cancer risk

Onions and garlic are key ingredients in sofrito, a condiment that's a staple of Puerto Rican cuisine. They may also be a recipe for reducing the risk of breast cancer. ...continue reading "Onions, Garlic, and Lower Risk of Breast Cancer"

Did you know that many tea bags contain plastic or are made totally from plastic? And that tiny pieces of plastic (microplastics) from these teabags are released into the hot water when brewing tea? Canadian researchers found that a single plastic teabag releases about 11.6 billion microplastic and 3.1 billion nanoplastic particles into the water during normal tea brewing. And no one knows what this is doing to us long term, but it is doubtful that ingesting billions of tiny plastic particles in each cup of tea is beneficial to health. View it as an "unknown risk".

The researchers point out that water is frequently at or above 95 degrees C (203 degrees F) when brewing tea, and that "food grade"plastics degrade or leach toxic substances when heated above 40 degrees C (104 degrees F). They tested 4 different commercial teabags in 95 degree C water for 5 minutes. Note: Boiling water is 100 degrees C or 212 degrees Fahrenheit. On the other hand, the researchers noted that few plastic particles were released into room temperature water.

Microplastics are particles ranging from 100 nm to 5mm in size, while nanoparticles are particles ≤ 100 nm in size. The researchers found that many, many more plastic particles were released into the water from the teabags than what has been reported in other foods (e.g. salt or bottled water).

There is another reason to also avoid plastic teabags - if the plastic contains phthalates (endocrine disruptors), it will leach them into the hot water. Which, of course, we are then drinking.

What to do? Just stick with the traditional paper teabags. But you'll have to do research to find one that has zero added plastic. Some bags may appear to be paper, but plastic may be coating the paper, or in the glue sealing sides of the bag. Or drink tea made from loose leaf tea. By the way, any company that advertises its tea bags as "silky", "silken sachets", or "mesh" is using plastic tea bags. There is no silk used. Also, assume that any company that won't tell you if it uses plastic in the tea bags, has plastic in the teabags.

Nowadays many foods come in plastic pouches that are meant to be heated - keep in mind that they probably all leach plastic particles into the food or liquid. If the idea of ingesting multitudes of tiny plastic particles concerns you - avoid heating foods in plastic pouches or containers. Instead, transfer into a glass, stainless steel or iron container for heating.

From Science Daily: Plastic teabags release microscopic particles into tea  ...continue reading "Are You Drinking Tiny Plastic Particles In Your Tea?"

There have been a number of studies finding microplastics (tiny bits of plastic smaller than 5mm) in seafood, drinking water, many foods, as well as in the air we breathe (e.g. from the breakdown of vehicle tires and brakes during normal use). There has been some concern over what the microplastics are doing to us because so little research has been done. But there is worry that the smallest sized microplastics are entering our bodies, traveling to different organs, and causing damage. But at least some of the microplastics we ingest are traveling through the gastrointestinal system  and then excreted in our stool, according to a recent study.

The study had 8 healthy volunteers from Europe and Asia (United Kingdom, Italy, Japan, Poland, Russia, Netherlands, Finland, and Austria). keep a food dairy for a week, and then "donate" a stool sample which was analyzed. None of the volunteers were vegetarians, and 6 had consumed fish from oceans in that week. [Note: Studies find that seafood contains microplastics.]

The  stool samples were analyzed for 10 types of plastic. All the stool samples contained microplastics, with polypropylene and polyethylene terephthalate being the most abundant. The samples contained an average of 20 microplastic particles per 10 g of stool. Since 9 types of plastic was detected in the stool, the researchers say that means they come from multiple sources.

Recently Canadian researchers estimated that annual consumption of microplastics ranges from 39,000 to 52,000 particles (depending on age and sex). When they added in inhalation of microplastic particles, the numbers increased to 74,000 to 121,000. And those who only drink bottled water may be getting an additional 90,000 microplastics (versus about 4000 microplastics from tap water). Yikes!

What to do if this concerns you? Since plastic wrappers, containers, and bottles (including water bottles) shed microplastics, then one can try to purchase and store foods in plain cardboard or glass containers. Stainless steel containers are also OK (NOTE: aluminum cans are usually coated with suspect chemicals). Definitely drink more tap water, and less bottled water.

From Medical Xpress: Microplastics detected in human stool   ...continue reading "Microplastics Are Found In Human Stool"