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We're surrounded by hormone disrupting chemicals (endocrine disruptors) in daily life - in plastics, personal care products, pesticides, food containers, plastic toys, etc.

A recent study done in the European Union (EU) reports on a growing body of evidence suggesting that exposures to endocrine-disrupting chemicals (EDCs), particularly phthalates and diphenyldichloroethene (DDE), contribute to the development of common reproductive disorders in women: endometriosis and uterine fibroids. A group of global EDC experts estimated the economic costs of these female reproductive disorders attributable to endocrine disrupting chemical exposures at nearly €1.5 billion ($158 billion) annually.

EDCs (like DDT and phthalates) are believed to contribute to health problems by mimicking, blocking, or otherwise interfering with the function of hormones by disrupting the signaling system the body uses to determine how cells develop and grow.

A number of studies suggest a byproduct of the pesticide DDT, a chemical known as DDE, can raise the risk of developing uterine fibroids, and that another group of chemicals called phthalates, which are found in plastic products and cosmetics, have been linked to a risk of edometriosis. Keep in mind that several other chemicals, such as PCBs, or polychlorinated biphenyls, and BPA have also been linked with female reproductive health problems. From Science Daily:

Chemical exposure linked to 1.4 billion euros in women's health care costs, study suggests

Endocrine-disrupting chemicals may contribute to reproductive health problems experienced by hundreds of thousands of women, costing European Union an estimated 1.4 billion Euros ($1.5 billion) a year in health care expenditures and lost earning potential, according to a new study. The study examined rates of uterine fibroids -- benign tumors on the uterus that can contribute to infertility and other health problems -- and an often painful condition called endometriosis where the tissue that normally lines the uterus develops elsewhere in the body. The two conditions are common, with as many as 70 percent of women affected by at least one of the disorders.

Research has linked the development of uterine fibroids and endometriosis to chemicals found in pesticides, cosmetics, toys and food containers. Past studies suggest a byproduct of the pesticide DDT, a chemical known as DDE, can raise the risk of developing uterine fibroids. Another group of chemicals called phthalates, which are found in plastic products and cosmetics, have been tied to growing risk of endometriosis.....DDT and phthalates are known endocrine-disrupting chemicals (EDCs)

"Although these two gynecological conditions affect millions of women worldwide, we recognize that this analysis only reflects the tip of the iceberg," Trasande said. "A growing body of evidence suggests EDC exposure is linked to a broader range of female reproductive problems, including polycystic ovary syndrome, infertility and pregnancy complications. These disorders also place a significant cost burden on women, their families and society as a whole.

A news story added some extra details and background to this story. From CNN:

Common chemicals linked to endometriosis, fibroids -- and healthcare costs

Hormone-disrupting chemicals are everywhere -- in plastics, pesticides and makeup -- and two of them, phthalates and DDE, have been particularly strongly linked with common female reproductive conditions, such as fibroids. In a new study, researchers estimate that the problems caused by these two chemicals alone could cost the European Union at least 1.41 billion euros a year, the U.S. equivalent of about $1.58 billion.

DDE is a breakdown product of the insecticide DDT that, although banned in the United States in 1972 and in Europe starting in the 1970s, still lingers in the environment and enters our body through food. The main exposure to phthalates is through eating food and drink stored in plastic containers that have phthalates.....In a similar way, they relied on a study that linked higher phthalate levels in women who had been diagnosed with endometriosis compared to healthy women.

The current study is important because it focused on chemicals that have not been restricted, and in the case of DDE -- which persists in the environment -- are not able to be restricted, Birnbaum said. However, she said she was surprised the researchers did not include an analysis of chemicals such as BPA, which has also been linked to endometriosis risk."This study is kind of a wake-up to say endocrine disruptors impact the female reproductive system, and we have some evidence they are associated with an increase in endometriosis and fibroids and it costs a lot of money," Birnbaum said.

Even with all the questions that remain, and few regulations in place, "there are safe and simple steps that families and women can take to reduce exposure to endocrine-disrupting chemicals," Trasande said. "They can eat organic, reduce canned food consumption, which reduces exposure to BPA, and avoid packaged or highly processed food, which is a major route for phthalates to enter food. They can also open windows to allow chemical dust, which accumulates on the carpet and electronics, to circulate out of homes."

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Did you ever wonder about all the consumer products that have fragrances in them and whether they are safe to use? Think of all the fragrances in personal care products and perfumes, in air fresheners, scented soaps, cleaning products, scented candles, even laundry detergents, and scented dryer sheets.

Fragrances are made up of many synthetic chemicals - with the "fragrance" in a product typically being a mixture of 50 to 300 chemicals. They are considered an important source of indoor air pollution and can have negative health effects on humans, especially developing fetuses and children. Fragrances are added to products to achieve a desired scent or mask other scents in the product. Air fresheners do not clean or freshen the air, but actually add chemicals to the air to mask other odors. Manufacturers are NOT required to disclose all the ingredients or chemicals in the products, and don't have to disclose any ingredients in any chemical mixture called "fragrance".

The few studies looking at health effects have found negative health effects, including on the lungs, respiratory effects, asthma, allergies, headaches, skin irritation, sensory irritation, hormonal effects, central nervous system effects, and inflammation. But more negative health effects are possible, especially because many of the chemicals are carcinogenic (cancer causing). We inhale the chemicals or absorb them through the skin, and from there they travel throughout the body - which is why they can be measured in the blood or urine.

Reading the studies that look at the chemicals emitted from scented products that people use every day can be overwhelming. Many of the studies specifically look at VOCs (volatile organic compounds) that the products emit, because these can affect air quality and human health. A big difficulty is that humans are exposed to mixtures of chemicals daily from many products, and the effects may take years to manifest themselves (such as cancer)

Bottom line: avoid, avoid, avoid fragranced or scented products if possible. Do not use scented detergent or dryer sheets (not necessary), do not use air fresheners (either in the home, workplace, or car), do not use incense or scented candles (post on scented candles). Read labels. Opening windows is the best way to air out a house or apartment. Studies find that fragrances labeled "organic", "natural", "green", or "with essential oils" basically emit the same toxic chemicals into the air (view such labels as marketing or "greenwashing") - therefore avoid those also.

Air fresheners are consumer products used in homes or in restrooms that typically emit fragrances,  including incense, scented candles, aerosol liquid wick and electric diffusers, and gels. Depending on which air freshener is used (and including those labeled "all natural"), they emit varying levels of allergens and toxic air pollutants (and which can also combine to produce other pollutants - "secondary pollutants"): acetone, aldehydes, benzene, toluene, formaldehyde, terpenes, styrene, esters, phthalates (which are hormone disrupting chemicals), limonene, and also ultrafine particles. None of these toxic chemicals are listed on the product labels. Typically, a fragrance is listed simply as “fragrance,” even though each fragrance can contain hundreds of individual chemicals. Only this past year has one company (Glade) started posting online (but not on the packages) some of the many chemicals used in its scented products.  ...continue reading "Health Reasons to Avoid Fragrances, Air Fresheners, Dryer Sheets"

There is increasing concern over phthalates and BPA and their effects on human health. It turns out that a big source of phthalates (which are known endocrine disruptors) in humans may be fast food.

A new study looked at fast food consumption by  8877 people and found that those who reported eating more of it in the past 24 hours had urinary phthalate levels as much as 40 percent higher than those who had eaten no fast food in the 24 hours before testing. In fact, it was dose-response relationship between fast food intake and exposure to phthalates - the more fast food, the higher the level of phthalates.

The researchers did not find an association between total fast food consumption and BPA. However, they did find an  association between fast food meat intake and BPA,  which corresponds to the small but growing evidence from other studies suggesting that hamburgers may be a source of BPA exposure.

These findings are of concern to all of us because phthalates and bisphenol A (BPA) are widely used industrial chemicals that may adversely impact human health. Studies detect phthalates in 98% of the US population. They are found in a wide variety of products (including plastics and personal care products), and can enter the human body via ingestion, inhalation, and absorption through the skin.

How are we exposed to them in fast food? Phthalates and BPA are typically found in food packaging and some leaches out into food. Some can also leach into food from dairy product tubing, in lid gaskets, food preparation gloves, conveyor belts, etc. Thus we ingest phthalates and BPA when we consume processed or packaged food. Fast food may be an especially important source of exposure to phthalates and BPA because it is highly processed, packaged, and handled.

Studies have demonstrated that the phthalates DEHP and DiNP are endocrine (hormone) disruptors, and that human exposure has been associated with adverse reproductive, neurobehavioral, and respiratory health effects. BPA is also an endocrine disruptor. We are all being exposed numerous ways, but the lower the levels, the better.

The good news is that once in the body, phthalates and BPA are quickly metabolized and excreted in urine, with elimination half-lives of less than 24 hours. Thus you can quickly reduce the levels in your body. And you should try.

From Science Daily: Fast food may expose consumers to harmful chemicals called phthalates

People who reported consuming more fast food in a national survey were exposed to higher levels of potentially harmful chemicals known as phthalates, according to a study published by researchers at Milken Institute School of Public Health (Milken Institute SPH) at the George Washington University.

"People who ate the most fast food had phthalate levels that were as much as 40 percent higher," says lead author Ami Zota, ScD, MS, an assistant professor of environmental and occupational health at Milken Institute SPH. "Our findings raise concerns because phthalates have been linked to a number of serious health problems in children and adults."Phthalates belong to a class of industrial chemicals used to make food packaging materials, tubing for dairy products, and other items used in the production of fast food. Other research suggests these chemicals can leach out of plastic food packaging and can contaminate highly processed food.

Zota and her colleagues looked at data on 8,877 participants who had answered detailed questions about their diet in the past 24 hours, including consumption of fast food. These participants also had provided researchers with a urinary sample that could be tested for the breakdown products of two specific phthalates--DEHP and DiNP.

Zota and her colleagues found that the more fast food participants in the study ate the higher the exposure to phthalates. People in the study with the highest consumption of fast food had 23.8 percent higher levels of the breakdown product for DEHP in their urine sample. And those same fast food lovers had nearly 40 percent higher levels of DiNP metabolites in their urine compared to people who reported no fast food in the 24 hours prior to the testing. The researchers also discovered that grain and meat items were the most significant contributors to phthalate exposure. Zota says the grain category contained a wide variety of items including bread, cake, pizza, burritos, rice dishes and noodles.

In addition, the researchers also looked for exposure to another chemical found in plastic food packaging--Bisphenol A or BPA. Researchers also believe exposure to BPA can lead to health and behavior problems, especially for young children. This study found no association between total fast food intake and BPA. However, Zota and her colleagues found that people who ate fast food meat products had higher levels of BPA than people who reported no fast food consumption.

Some more bad news about BPA and other endocrine disruptors (hormone disruptors) such as the phthalate DEHP. Bottom line: Avoid plastics, BPA, BPS and other BPA substitutes (they're chemically similar and seem to have similar health effects) as much as possible. Most canned food has BPA or BPA substitutes in the can linings. Use glass and stainless steel to store food, microwave food in dishes (not in plastic containers or packages). Go to the Environmental Working Group site for more information on product information, what to avoid, and what to look for and get instead.

From Science daily: BPA substitute can trigger fat cell formation: Chemical used in BPA-free products exhibits similar endocrine-disrupting effects

Exposure to a substitute chemical often used to replace bisphenol A in plastics can encourage the formation of fat cells, according to a new study. The replacement chemical, bisphenol S, has a slightly different chemical structure than bisphenol A (BPA), a known endocrine disruptor. As of 2014, nearly 100 epidemiological studies have been published tying BPA to health problems, according to the Introductory Guide to Endocrine-disrupting Chemicals published by the Society and IPEN, a global network that supports sound chemicals management.

Concerns about BPA's health effects have encouraged some consumers to purchase food containers labeled "BPA-free." BPA-free products often contain bisphenol S (BPS)or other substitutes, but researchers have raised concerns that these replacements also interfere with the body's hormones and may pose similar threats to public health."Our research indicates BPS and BPA have comparable effects on fat cells and their metabolism," said the study's senior author, Ella Atlas, PhD, of Health Canada, the federal department responsible for helping Canadians maintain and improve their health. 

A report (a collaborative effort of 5 organizations) that looked for the presence of BPA and BPA substitutes in the linings of food cans from major food companies. And yes, they found BPA in most cans (67%). From the group Toxic Food Cans: Buyer Beware: Toxic BPA and regrettable substitutes found in the linings of canned food

This study set out to analyze the interior coatings and lids of nearly 200 canned foods collected in 19 states and one Canadian province to determine whether the use of bisphenol A (BPA) continues to be widespread among major national brands and retailers of canned foods. We also wanted to determine what replacement materials for BPA-based epoxy are being used by retailers and manufacturers and the extent to which those companies have studied the safety of those materials.

Our findings were alarming: This report validates our concerns that, despite consumer demand for BPA-free cans, 67 percent (129 of 192) of the cans we tested contained BPA-based epoxy in the body and/or the lid. Our investigation also found, for the first time, that some retailers and brands have replaced BPA with PVC, made from vinyl chloride, a carcinogen.

BPA is a hormonally active chemical. The scientific evidence linking BPA exposure to harm in humans is compelling and growing: More than 300 animal and human studies have linked exquisitely small amounts of BPA exposure, measured in parts per billion and even parts per trillion, to a staggering number of health problems, including breast and prostate cancer, asthma, obesity, behavioral changes (including attention deficit disorder), altered development of the brain and immune system, low birth weight and lowered sperm counts.

This study looked at plasticizers called phthalates (which are commonly found in medical tubes), and which also have endocrine disrupting effects. From Medical Xpress:  Attention deficit after kids' critical illness linked to plasticizers in medical tubes

Children who are often hospitalized in intensive care units are more likely to have attention deficit disorders later, and new research finds a possible culprit: a high level of plastic-softening chemicals called phthalates circulating in the blood. The researchers.....suggest these chemicals, which are added to indwelling medical devices such as plastic tubes and catheters, seep into the child's bloodstream.

"Phthalates have been banned from children's toys because of their potential toxic and hormone-disrupting effects, but they are still used to soften medical devices," said lead researcher Sören Verstraete, MD, a PhD student at KU (Katholieke Universiteit) Leuven in Leuven, Belgium. "We found a clear match between previously hospitalized children's long-term neurocognitive test results and their individual exposure to the phthalate DEHP during intensive care."

Di(2-ethylhexyl)phthalate, or DEHP, is the most commonly used plastic softener in medical devices made of polyvinyl chloride (PVC). Verstraete called the use of medical devices containing this phthalate "potentially harmful" for the brain development and function of critically ill children.

Yes, the chemicals in personal care products and cosmetics you use absolutely get into your body, have effects, and can be measured in the urine. Of especially big concern are the endocrine (hormone) disrupting chemicals such as phthalates, parabens, triclosan, and oxybenzone (BP-3). This study shows that even taking a 3 day break from these chemicals lowers their levels in your body. The researchers found that : "The adolescent girls in this study experienced an average within girl decline of 27-45% in urinary concentrations of certain phthalates, certain parabens, triclosan, and oxybenzone after three days of abstaining from conventional personal care products and using replacement products with labels indicating they did not contain these chemicals."

Bottom line: Read the ingredient lists of all personal care products and try to avoid those with phthalates, parabens, triclosan, and oxybenzone (BP-3). Try to buy "unscented" or "fragrance-free" products.The site ewg.org also has lists of personal care products to avoid, and rates many products. From Science Daily:

Teen girls see big drop in chemical exposure with switch in cosmetics

A new study led by researchers at the University of California, Berkeley, and Clinica de Salud del Valle de Salinas demonstrates how even a short break from certain kinds of makeup, shampoos and lotions can lead to a significant drop in levels of hormone-disrupting chemicals in the body. The results, published Monday, March 7, 2016 in the journal Environmental Health Perspectives, came from a study of 100 Latina teenagers participating in the Health and Environmental Research on Makeup of Salinas Adolescents (HERMOSA) study.

Researchers provided teen study participants with personal care products labeled free of chemicals such as phthalates, parabens, triclosan and oxybenzone. Such chemicals are widely used in personal care products, including cosmetics, fragrance, hair products, soaps and sunscreens, and have been shown in animal studies to interfere with the body's endocrine system.

"Because women are the primary consumers of many personal care products, they may be disproportionately exposed to these chemicals," said study lead author Kim Harley, associate director of the UC Berkeley Center for Environmental Research and Children's Health. "Teen girls may be at particular risk since it's a time of rapid reproductive development, and research has suggested that they use more personal care products per day than the average adult woman."

Analysis of urine samples before and after a three-day trial in which the participants used the lower- chemical products found significant drops in levels of these chemicals in the body. Metabolites of diethyl phthalate, commonly used in fragrances, decreased 27 percent by the end of the trial period. Methyl and propyl parabens, used as preservatives in cosmetics, dropped 44 and 45 percent respectively. Both triclosan, found in antibacterial soaps and some brands of toothpaste, and benzophenone-3 (BP-3), found in some sunscreens under the name oxybenzone, fell 36 percent. Surprisingly, there was a small increase in concentrations in two less common parabens. Those levels were small and could have been caused by accidental contamination or a substitution not listed on the labels, the study authors said.

The researchers noted that cosmetics and personal care products are not well-regulated in this country, and that getting data about health effects from exposure, particularly long-term ones, is difficult. But they say there is growing evidence linking endocrine-disrupting chemicals to neurobehavioral problems, obesity and cancer cell growth. (Original study.)

More and more negative news about phthalates: men with greater exposure to DEHP (a phthalate) have lower sperm motility (how the sperm move or their ability to swim), and pregnant women with higher levels of phthalates have a higher rate of pregnancy loss (miscarriages - mainly between 5 and 13 weeks of pregnancy). Phthalates are found in many plastics, are thought to be endocrine disruptors, and can be measured in urineFrom Medical Xpress: Lower sperm motility in men exposed to common chemical

Men with higher exposure to the substance DEHP, a so-called phthalate, have lower sperm motility and may therefore experience more difficulties conceiving children, according to a Lund University study. Phthalates is an umbrella term for a group of substances based on phthalic acid, some of which are suspected to be endocrine disruptors. Many phthalates are found in soft plastics in our daily surroundings.... Since phthalate molecules leak out of plastics, we are exposed to it daily and absorb the chemicals through food, drink, skin contact and inhalation. 

"We have studied metabolite levels of the phthalate DEHP (diethylhexyl phthalate) in urine as an indicator of exposure, as well as the semen quality of 300 men between the ages of 18 and 20. The results show that the higher metabolite levels the men had, the lower their sperm motility was", says Jonatan Axelsson, researcher at the Department of Laboratory Medicine, Lund University. For the one quarter of the men with the lowest levels of exposure, 57 per cent of the sperm cells were moving forward, compared to 46 per cent for the quarter of the men with the highest levels of exposure.

As previous research has reported that there is a linear connection also between sperm motility and chances of becoming pregnant, the findings could indicate that the more exposed one is to DEHP, the smaller the chances are of having children.

From Medical Xpress:  Exposure to phthalates could be linked to pregnancy loss

A new study of more than 300 women suggests that exposure to certain phthalates—substances commonly used in food packaging, personal-care and other everyday products—could be associated with miscarriage, mostly between 5 and 13 weeks of pregnancy

Out of concern over the potential health effects of phthalates, the U.S. has banned six of these substances from use in certain products made for young children. But many are still included as ingredients in paints, medical tubes, vinyl flooring, soaps, shampoos and other items. Research on phthalates has shown that long-term exposure to low levels of the some of these compounds harms lab animals' health and can increase their risk for pregnancy loss. Additionally, at least one study found that female factory workers exposed to high levels of phthalates through their work were at a higher risk for miscarriage.

The researchers tested urine samples from 132 women who had miscarriages and 172 healthy pregnant women in China. They found pregnancy loss was associated with higher levels of urinary phthalate metabolites from diethyl phthalate (DEP), di-isobutyl phthalate (DiBP) and di-n-butyl phthalate (DnBP). Although this doesn't prove that phthalates cause pregnancy loss, the study suggests an association exists that the researchers say should be studied further.

When we think about air pollution, we usually think about pollutants in the air that we breathe in. But there is a growing body of evidence that some pollutants found in the air, including a group of chemicals called phthalates, can be absorbed directly through the skin (dermal absorption or dermal intake). A recent study has found that the skin absorption of certain phthalates (DERP and DnBP) is comparable to that from inhalation.

Phthalates are linked to a number of negative health effects, and so we should try to minimize our exposure to them.(Oct. 8, 2015 post and Sept. 29, 2015 post). The findings of this study is another strong argument against using scented products in the home, because phthalates are found in fragrances - whether air fresheners, scented candles, perfumes, dryer sheets, etc. Just think of them as indoor air pollution. From Environmental Health Perspectives:

Transdermal Uptake of Diethyl Phthalate and Di(n-butyl) Phthalate Directly from Air: Experimental Verification

Fundamental considerations indicate that, for certain phthalate esters, dermal absorption from air is an uptake pathway that is comparable to or greater than inhalation. Yet this pathway has not been experimentally evaluated and has been largely overlooked when assessing uptake of phthalate esters.This study investigated transdermal uptake, directly from air, of diethyl phthalate (DEP) and di(n-butyl) phthalate (DnBP) in humans.  ...continue reading "We Are Absorbing Some Air Pollutants Through Our Skin"

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 Several people have recently asked me whether scented candles have any health effects. The answer is a big YES - they have many negative health effects, and so do other scented products such as air fresheners and dryer sheets (e,g, Bounce). All of them contain fragrances and other chemicals - all from petrochemicals (which means they are chemical products derived from petroleum). And yes - all 3 products are totally unnecessary, so ditch them for better health. View all of them as sources of indoor air pollution.

Most of the candles on the market are made with paraffin wax, derived from petroleum, and scented with synthetic fragrances, also derived from petroleum. Synthetic fragrances typically also contain phthalates that can interfere with your hormone system (endocrine disruptors).

In one study scientists at the South Carolina State University lit several brands of candles made of paraffin – the most common and inexpensive candle wax – as well as soy candles (thus vegetable based) and burned them for 5 to 6 hours in a chamber. All of the candles were unscented and undyed. They found that the paraffin candle smoke emits varying levels of pollutants, including benzene, toluene and ketones, as well as hydrocarbon chemicals called alkanes and alkenes, which are components of gasoline. They have been linked to cancer, asthma and birth defects. None of the vegetable-based soy candles produced toxic chemicals. From SC State University:  Frequent use of certain candles produces unwanted chemicals

Researchers point out that the emissions from burning an occasional paraffin candle will not likely cause health problems - it's the frequent lighting of scented paraffin candles in indoor rooms, and inhaling the pollutants in the air that may cause health problems, or as Dr. Massoudi of S. Carolina State University stated: "could contribute to the development of health risks like cancer, common allergies and even asthma."

Scented candles are known to release various volatile organic compounds (VOCs) including both pleasant aromas and toxic components both before lighting (unlit) and when lit. When lit, the "highest emission concentration" was of formaldehydeCharacterization of hazardous and odorous volatiles emitted from scented candles before lighting and when lit

By simply touching the candles, one absorbs chemicals through the skin.  Skin contact transfer of three fragrance residues from candles to human hands.

Safe candle alternatives are beeswax candles and unscented soy candles. These do not emit toxic chemicals when burned. However, all burning candles emit soot, which is ultrafine, lung-damaging particulate matter that's capable of penetrating deep into the lungs.

From Huffington Post: The Big Problem With Scented Candles

Scented candles are one of the easiest and most effective ways to mask unpleasant odors in your home....But one of the main problems with scented candles is the scent itself. According to Anne Steinemann, an environmental pollutants expert who is a professor of civil engineering and the chair of sustainable cities at the University of Melbourne, certain candles may emit numerous types of potentially hazardous chemicals, such as benzene and toluene. They can cause damage to the brain, lung and central nervous system, as well as cause developmental difficulties.

"I have heard from numerous people who have asthma that they can’t even go into a store if the store sells scented candles, even if they aren’t being burned," Steinemann added. "They emit so much fragrance that they can trigger asthma attacks and even migraines."

Researchers at South Carolina State University tested both petroleum-based paraffin wax candles and vegetable-based candles that were non-scented, non-pigmented and free of dyes. Their 2009 report concluded that while the vegetable-based candles didn't produce any potentially harmful pollutants, the paraffin candles "released unwanted chemicals into the air," said chemistry professor Ruhullah Massoudi in a statement.

It may be shocking to think that your favorite candles could potentially be bad for you, and made worse by added fragrances. Steinemann said for some people, the effects are "immediate, acute and severe," while others may not realize they are being effected until they gradually develop health issues.

Though the risk to you may be small, there are alternatives. Steinemann suggests going the unscented route, avoiding "even those with essential oils, as they can potentially have hazardous chemicals," she said. "It's almost like air fresheners with the fragrance just sitting there ... permeating surfaces in the room."

 More and more studies are finding negative health effects from hormone disrupting chemicals (which we are exposed to every single day, and subsequently which are in all of us), such as parabens, phthalates, Bisphenol-A (BPA), and chemical substitutes for BPA such as Bisphenol-S (BPS) and BPF.  The last post had some recent studies that looked at health effects of hormone disrupting chemicals. The following article points out some of the many difficulties in developing packaging that is safe and doesn't leach endocrine disrupting chemicals or even other chemicals.

We generally focus on hormone disrupting chemicals in plastic bottles or metal cans (which their epoxy liners), but other parts of packaging may (or may not) also leach chemicals. Some leaching may occur with the adhesives used to seal foil pouches, and the polypropylene inner layers also may leach stabilizers. Glass jars are OK, but jar lids may be equipped with BPA-based epoxy liners and/or gaskets that leach plasticizers. Greaseproof wrappers may leach poly- and perfluorinated compounds used to make some packaging greaseproof (may occur if packaging is from India and China - because it is legal to import into USA and use).  Some ceramic kitchenware - the glazes used in artisanal pottery and older mass produced ceramics may leach toxic metals, especially lead. There can even be "offset migration" which occurs when the printed outer surface of food packaging transfers chemicals to the inner food-contact surface.  Whew...

Bottom line: Even BPA alternatives (labeled BPA-free) should be viewed as the same as BPA (as endocrine disruptors) - in other words, currently there are no good BPA substitutes. Read labels and try to minimize plastics in personal care products (e.g., lotion, fragrances) and your food if possible (e.g., choose glass, stainless steel, wax paper, aluminum foil). This is especially important during pregnancy.  Don't microwave food in a plastic dish or container, or covered with plastic wrap. Eat fresh foods and try to avoid soda cans and other packaged, processed foods, especially in plastic containers or metal cans. From Environmental Health Perspectives: A Hard Nut to Crack: Reducing Chemical Migration in Food-Contact Materials

When we buy food, we’re often buying packaging, too. From cherries to Cheez-It® crackers, modern foods are processed, transported, stored, and sold in specialized materials that account, on average, for half the cost of the item, according to Joseph Hotchkiss, a professor in Michigan State University’s School of Packaging. Consumer-level food packaging serves a wide range of functions, such as providing product information, preventing spoilage, and protecting food during the journey from production to retail to pantry, fridge, or freezer. That’s why food producers lavish so much time and money on it.

But what happens when these valuable and painstakingly engineered containers leach chemicals and other compounds into the food and drink they’re designed to protect? Such contamination is nearly ubiquitous; it happens every day, everywhere packaged food is found, with all common types of packaging, including glass, metal, paper, and plastic. Even as awareness of the issue grows, large-scale solutions that are scientifically and financially viable remain out of reach. The challenges in reaching them are many.  ...continue reading "Chemicals Migrate From Containers to Food"

A report released this week by the Endocrine Society states that the list of health problems that scientists can confidently link to exposure to hormone-disrupting chemicals has grown to include: diabetes, cardiovascular disease, obesity, reproductive and developmental problems, thyroid impairment, certain reproductive cancers, and neurodevelopmental problems such as decreased IQ. This statement (report) is based on the summaries of 1300 studies on endocrine disrupting chemicals (EDCs), and it also adds support to the idea that even minute doses of these chemicals can interfere with the activity of natural hormones, which play a major role in regulating physiology and behavior. The statement also stated that most industrial chemicals released into the environment—numbering in the tens of thousands—have never been tested for endocrine-disrupting potential. EDCs include such common chemicals as bisphenol A (BPA), phthalates, parabens, some pesticides (e.g., atrazine), flame retardants, some persistent organic pollutants, and dioxins.

Where are endocrine disruptors found? People are exposed to chemicals with estrogenic effects in their everyday life, because endocrine disrupting chemicals are found in low doses in thousands of products. Many plastic products, including those advertised as "BPA free", have been found to leach endocrine-disrupting chemicals (the substitute chemicals are no better than BPA, and may be worse). Examples: plastic food containers which then leach into foods, linings of metal beverage, formula, and food cans, soft plastic toys, dental sealants, consumer goods, receipts, personal care products that contain parabens or phthalates (e.g., found in lotions,sunscreens, fragrances), household products (such as cleaning products, vinyl shower curtains) , cars (that new car smell in car interiors), etc. Americans love plastics, but there is a serious human health cost.

NOTE: To minimize EDC exposure - try to avoid plastic food and beverage containers. Instead try to use glass, stainless steel, or ceramics. Eat as many unprocessed and fresh foods as possible. Use cloth shower curtains. Read labels and avoid BPA, phthalates, parabens. Avoid fragrances. Don't use or buy non-stick pans, stain and water-resistant coatings on clothing, furniture and carpets. When buying new furniture, check that it doesn't have added fire retardants.

Of course any public discussion of the harms from endocrine disrupting chemicals, as well as the newly released Endocrine Society report, is drawing sharp criticisms from the chemical industry (especially the American Chemistry Council, the largest trade group for the chemicals industry). Of course. We all know that the lobbying efforts by the chemical industry to suppress and deny the evidence of harm to humans from EDCs has been and will continue to be massive. Sadly, but at this point EDCs are found in almost everyone on earth. More about the report, from Science Daily:

Chemical exposure linked to rising diabetes, obesity risk

Emerging evidence ties endocrine-disrupting chemical (EDC) exposure to two of the biggest public health threats facing society -- diabetes and obesity. EDCs contribute to health problems by mimicking, blocking or otherwise interfering with the body's natural hormones. By hijacking the body's chemical messengers, EDCs can alter the way cells develop and grow. Known EDCs include bisphenol A (BPA) found in food can linings and cash register receipts, phthalates found in plastics and cosmetics, flame retardants and pesticides. The chemicals are so common that nearly every person on Earth has been exposed to one or more.  ...continue reading "New Report About Harms of Endocrine Disruptors"