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Author: Sima

Published on Leave a comment on Vitamin C Is Important For Aging Brain Health

We all know that vitamin C is important for our health, especially skin health, but it is also important for a healthy brain. A recent study found higher levels of vitamin C in aging adults is linked to a healthier aging brain. Nutrition matters!

The study found that having low levels of vitamin C in blood plasma in aging adults is correlated with having lower brain gray matter volume and connectivity. The study looked at 2040 aging adults (median age 69 years) in Japan - using both MRI scans and blood plasma samples.

As we age, the volume of the brain shrinks - this is normal. There are both structural and connectivity changes - again, it's normal.  But...you want to delay and minimize these changes, which is why this research finding that vitamin C is important for aging brain health is significant. As the researchers point out, one can make nutritional changes by increasing vitamin C foods in the diet. (BTW, generally foods are superior to supplements.)

Gray matter of the brain is where processing information, movement, and emotion control occur. It has an effect on new memories and multitasking.

Other studies have also pointed out that vitamin C are important for aging brain health. Lower levels of vitamin C have been associated with a higher risk of dementia and other neurodegenerative diseases.

Bottom line: Try to eat foods high in vitamin C frequently, preferably daily.

From  Science Daily: Scientists discover a surprising link between vitamin C and brain health

Researchers have found another clue that diet may influence how the brain ages. In a study of more than 2,000 older adults in Japan, people with lower levels of vitamin C in their blood tended to have less gray matter and weaker connections within an important brain network involved in memory and attention. While the findings do not prove that vitamin C protects the brain, they strengthen evidence that good nutrition could play a role in maintaining cognitive health later in life. ...continue reading "Vitamin C Is Important For Aging Brain Health"

Published on Leave a comment on Large Study Finds Vitamin D and Calcium Supplements Do Not Prevent Fractures

Uh-oh, two popular supplements don't have the health benefits that many think. Millions take vitamin D or calcium (or both) for stronger bones. A large review of 69 studies found that taking calcium or vitamin D or both does not prevent fractures and falls in older adults.

Other studies have had similar results. Bottom line: Focus on eating well and getting enough exercise, especially resistance exercises and balance exercises.

From Science Daily: Millions take calcium and vitamin D for stronger bones. A major review finds little benefit

A comprehensive review published in The BMJ suggests that calcium supplements, vitamin D supplements, or taking both together provide little to no clinically meaningful benefit in preventing fractures or falls for most older adults. ...continue reading "Large Study Finds Vitamin D and Calcium Supplements Do Not Prevent Fractures"

Published on Leave a comment on Sitting Many Hours A Day Has Health Harms

We all know that there are lots of health benefits, such as better heart health, to being more physically active. In contrast, a recent study found health harm from sitting more during leisure time and increased risk of early death, especially from cardiovascular disease (heart disease).

The study found that physical activity could not overturn the effects of prolonged sitting (6 or more hours every day) during leisure time - but it did help. Best was sitting the least (less than 3 hours per day) and being the most active.

Those who both sat more (6 or more hours per day) and were less physically active were more likely to have an early death - 94% increase in women and 48% more likely for men (when compared to those who sat the least and were the most physically active).

Bottom line: Turn off the TV, put away the cell phone, and get up and move!

From Science Daily: More time spent sitting linked to higher risk of death; Risk found to be independent of physical activity level

A new study from American Cancer Society researchers finds it's not just how much physical activity you get, but how much time you spend sitting that can affect your risk of death. Researchers say time spent sitting was independently associated with total mortality, regardless of physical activity level. They conclude that public health messages should promote both being physically active and reducing time spent sitting. ...continue reading "Sitting Many Hours A Day Has Health Harms"

Published on Leave a comment on Study Finds Tylenol Use During Pregnancy Safe

Is Tylenol (acetaminophen) use during pregnancy actually linked or a cause of autism? A large recent study says NO - there is no link between acetaminophen (also called paracetamol) use during pregnancy and autism. Whew..

The long-running well-done study conducted in Hong Kong did NOT find a link with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) in the children born to women who took paracetamol (acetaminophen) during pregnancy. Dose taken and timing (taken early or late in pregnancy) did not change the results of the study. The study included 708,020 mother-child pairs (of these approximately 43.3% had prenatal paracetamol exposure). and they were studied for many years.

For years Tylenol was considered safe to take during pregnancy for pain and fevers. Apparently it is still safe.

From Medical Xpress: Should pregnant women worry about taking Tylenol? 20-year sibling-matched study finds no link to autism or ADHD

Tylenol (also known as acetaminophen or paracetamol) is one of the most widely used over-the-counter options for easing pain and reducing fever, including during pregnancy. More recently, safety concerns around use during pregnancy have gained attention, with claims of a possible link between prenatal exposure and autism in children increasingly appearing in news headlines and prime-time debates. ...continue reading "Study Finds Tylenol Use During Pregnancy Safe"

Published on Leave a comment on Unsafe Pesticide Applications

It continues to amaze me that people applaud the use of frequent heavy duty pesticides, especially for cosmetic reasons (e.g., to have lawns look like carpets).  Do they not realize that there are health harms, and so should be used only when necessary?

Well, I recently traveled out of the country and was surprised, even shocked, that some (high end) hotels do routine daily pesticide applications in their gardens, both using a sprayer and fumigation. They even fumigate routinely among people sitting and even dining outside! After asking, I found out that the hotel does this because their customers don't want to see any insects and the daily fumigation shows that "action is being taken".

Are you kidding me? The applicator didn't even wear gloves, and walked along a driveway, as well as a stone terrace next to a building - fumigating all the while. And people just sat there! (My photos were taken through a window.) And by the way, throughout the city there were very few insects, including mosquitos. So was the hotel's fumigation all performative, for show?

What I'm also wondering is whether the pesticide applicator knew about long-term health harms to him, such as cancer and neurological damage?

Published on Leave a comment on Many Studies Link A Commonly Used Pesticide To Health Harms

It has long been known that the pesticide chlorpyrifos has harmful health effects on humans, especially developing fetuses and children. Unfortunately, it is still in use.

A recent review of nearly 300 studies looking at chlorpyrifos found that the pesticide has harmful effects throughout the body, also causes DNA damage, harms children's brains and nervous systems, causes cancer.and that harmful effects are found at levels that are considered safe by the EPA. Unfortunately, more health harms are found each year.

While the pesticide is no longer allowed to be used for household use in the US (remember cans of Raid cockroach killer?), it is still allowed to be used on farms, in greenhouses, golf courses, and more. Keep in mind that industry-funded studies of chlorpyrifos have been used to shape federal policy and exposure limits for decades.

In other words, federal standards do not protect public health. Why is that not surprising?

Excerpts from the investigative journalism site U.S. Right To Know: Nearly 300 studies link the common pesticide chlorpyrifos to multi-organ damage, DNA disruption, and chronic disease 

Key findings:

    • A review of nearly 300 studies summarizes evidence that chlorpyrifos may harm multiple systems throughout the body, including the brain, hormones, liver, gut microbiome, muscles, reproductive organs, and bones.
    • The review describes DNA damage, chromosome instability, and epigenetic changes that may alter how genes function long after exposure.
    • Some harmful effects appear at exposure levels below those considered safe under current pesticide exposure testing standards.

...continue reading "Many Studies Link A Commonly Used Pesticide To Health Harms"

Published on Leave a comment on Areas of High Pesticide Use and Cancer Rates

People assume that if a pesticide is allowed to be used, than it must be safe. Wrong! Pesticides are registered with the government precisely because they are dangerous.

We are not exposed to just one pesticide at a time, but mixtures of pesticides - for example, in the foods we eat, our yards, our homes, our water, and even our air (from drift). The big question is: What (if anything) are these pesticide mixtures doing to us?

A recent study conducted in Peru set out to answer the question regarding exposure to pesticide mixtures. They compared heavily agricultural areas (lots of pesticides applied) and non-agricultural areas throughout the country. 31 pesticides were looked at, and yet none of these are considered cancer-causing (according to the World Health Organization).

They researchers found up to 150% higher incidence of cancers in the regions with higher environmental pesticide exposure. There were cancer "hot-spots" in the country, and different cancers depending on the pesticide mixtures people are predominantly exposed to.

By the way, finding increased cancers in both adults and children in heavy pesticide use areas (generally agricultural areas), is also found in other studies. The people exposed to the most are farmworkers, their families, and anyone living near farms. But also anyone with pets (e.g., flea treatments), and anyone having pesticide treatments in their homes or in their yards. People also ingest pesticides/pesticide residues from the foods they eat.

From Science Daily: Pesticide exposure linked to 150% higher cancer risk in major study

A major new study published in Nature Health has found a strong connection between environmental exposure to agricultural pesticides and an increased risk of cancer. By combining environmental monitoring, national cancer registry data, and biological research, scientists from the IRD, Institut Pasteur, University of Toulouse, and the National Institute of Neoplastic Diseases (INEN) in Peru provide new insight into how pesticide exposure may contribute to the development of certain cancers. ...continue reading "Areas of High Pesticide Use and Cancer Rates"

Published on Leave a comment on Study Finds That A Common Infant Procedure is Unnecessary
Breastfeeding
Credit: Wikimedia Commons/ Anton Nosik

For a while now mothers having trouble breastfeeding their infants have been blaming it on the infants having "tongue-tie"(upper lip frenulum). This then results in the infant having to go through a procedure of cutting the upper lip frenulum (located in the mouth).

A new study found that the procedure is usually unnecessary, and that the breastfeeding troubles instead seem to stem from the mother's inexperience with breastfeeding.

The researchers studied 264 mother-infant pairs and found no association between the anatomical characteristics of the upper lip frenulum and breastfeeding problems. What was more important was whether the mother had prior breastfeeding experience. Also, the researchers found that true tongue-tie is rare.

Other studies also find that true tongue-tie is rare. Decades ago the problem of tongue-tie was almost unheard of, yet nowadays it seems to be commonly blamed for any and all breastfeeding difficulties. Instead, the researchers suggest that first-time mothers attempting to breast feed their infants should be given support until breast-feeding goes smoothly.

Hopefully there soon will be a reduction in the number of these unnecessary procedures done.

From Medical Xpress: A common newborn procedure faces new scrutiny as evidence undercuts one widely blamed cause of breastfeeding trouble

A joint study by the University of Oulu and Oulu University Hospital suggests that a newborn's upper lip frenulum is unlikely to be a major cause of breastfeeding difficulties. The study, published in JAMA Network Open, followed 264 mother–infant pairs at Oulu University Hospital between 2023 and 2024. Researchers assessed the anatomy and mobility of the upper lip frenulum in healthy, full-term infants and compared the findings with mothers' reported breastfeeding experiences. ...continue reading "Study Finds That A Common Infant Procedure is Unnecessary"

Published on Leave a comment on The Supplement Glucosamine May Accelerate Dementia

The popular supplement glucosamine has been taken for decades for joint health. However, new research suggests that regular use of the  supplement can increase the risk for developing dementia, specifically increasing the progression from mild cognitive impairment to dementia.

Not only did it accelerate the progression from mild cognitive impairment to Alzheimer's disease, but it also worsened survival.

Uh oh. It seems that so many supplements start out looking good, but turn out to have a dark side.

From Medical Xpress: A popular joint pain supplement may accelerate dementia

New research has found an association between taking glucosamine, a popular over-the-counter supplement used for joint pain, and a higher likelihood of progressing from mild cognitive impairment to Alzheimer's disease. The finding by University of Florida neuroscientists is based on a large retrospective analysis of patients' records as well as supporting data from advanced imaging technology used to scan human brain specimens and Alzheimer's disease mouse models. ...continue reading "The Supplement Glucosamine May Accelerate Dementia"

Published on Leave a comment on Cancer Vaccine For Melanoma Looks Very Promising
Melanoma skin cancer Credit: Wikipedia

The skin cancer melanoma is an incredibly deadly cancer if not caught in the early stages. This is why researchers have been studying various types of immunotherapy as a treatment for melanoma - but with inconsistent results (works for some, but not all).

Exciting new research was recently published that found that personalized vaccine plus the immunotherapy drug pembrolizumab (Keytruda) could be very successful as a melanoma treatment. Using Keytruda alone is current melanoma treatment, but adding the vaccine to Keytruda significantly improved the results.

The researchers found that a personalized vaccine called intismeran, when combined with Keytruda, cut the risk of recurrence and death from melanoma by 49% five years after the original melanoma tumors were removed. The comparison group was patients receiving just Keytruda alone. Key finding: "After five years of follow-up, 68.8% of patients who took the combination therapy remained cancer free while 49.1% of the patients in the pembrolizumab-alone group had no signs of cancer."

The combination treatment also cut the risk of the original cancer metastasizing to distant parts of the body by 59% (this was at the 5 year follow-up). Overall survival for the combination group at the 5 year follow-up was 92.2%, while for Keytruda alone it was 71.3%. Again, a significant difference

Even though this combination treatment was tested on a small group of patients (107 patients), this is a fabulous result! More expanded testing is underway. Stay tuned!

From Medical Xpress: Cancer vaccine sustains 49% melanoma reduction after 5 years

The combination of a vaccine and a drug, which both harness the immune system to attack cancer cells, has proven successful in cutting the risk of skin cancer recurrence and death by 49%, a new study shows. This reduction was calculated five years after patients had their tumors surgically removed and remains unchanged. ...continue reading "Cancer Vaccine For Melanoma Looks Very Promising"