endocrine disruptors – Lacto Bacto

Pesticides and Breast Cancer

SimaDecember 13, 2025December 14, 2025Leave a comment

Normal (left) vs cancerous breast (right), mammography image
Credit: National Cancer Institute

Many studies link pesticide exposure to the development of various cancers, including breast cancer. We tend to think of pesticide exposure as occurring when there is direct contact with the pesticide - for example during application, or when walking on lawns or areas with freshly applied pesticides. Yet... there are other routes that have been neglected in studies, such as washing pesticide contaminated clothes.

At a recent webinar (42nd National Forum Series - The Pesticide Threat to Environmental Health), Carolina Panis, PhD, (Ass. Professor of Medicine at Western Paraná State University in Brazil, and Visiting Researcher at Harvard University and the University of Arizona) spoke about pesticide exposure in women and breast cancer. She discussed her recent research showing that women occupationally exposed to pesticides (e.g., as farm workers) and diagnosed with breast cancer seem to have more aggressive disease, also at younger ages, than unexposed women. An increased mortality rate went along with this.

She also discussed an interesting finding regarding women living in farm areas (with heavy pesticide use) in Brazil. Not only is occupational exposure to pesticides linked to breast cancer, but additionally - women having chronic (daily) exposure are also exposed to pesticide residues when washing clothing used by someone who had applied pesticides. Laundry exposure! Women absorb pesticide residues (e.g., glyphosate, atrazine) from the pesticide contaminated clothing, which increases the amount of pesticides in their bodies and this is also linked to breast cancer.

The women she looked at lived in farming areas, and additionally many had their residences frequently sprayed for insects. Ultimately, women exposed to high levels of pesticides tend to develop metastatic untreatable breast cancer, and at a younger age (unlike other areas where breast cancer is highly treatable). She pointed out that pesticides also have a negative effect on the immune system.

From the article by C. Pannis and B. Lemos: Pesticide Exposure and Increased Breast Cancer Risk In Women Population Studies

Women in rural regions are at risk for exposure to pesticides by equipment decontamination, unprotected clothes washing, pesticide drift, chemical spraying in the field, and other routes of exposure in the household. Pesticides can act on mammary gland cells in direct and indirect ways, augmenting the risk for breast cancer development. ...continue reading "Pesticides and Breast Cancer"

Male Sperm Counts Continue to Decline

SimaDecember 11, 2025December 14, 2025Leave a comment

When looking at the research, it is striking that so many chemicals that we are exposed to daily are harming us. Health harms include an increase in certain cancers (e.g., brain cancer and leukemia from certain pesticides) and reproductive effects. This can be seen clearly when research shows that sperm counts are declining globally 2.64% per year since 2000.

A recent report from HEAL (Health and Environmental Alliance in the European Union) found that along with this, infertility rates, testicular cancer, and prostate cancer are increasing. This is alarming!

HEAL’s report (author Dr. Cannarella) details alarming indications of catastrophe in male reproductive health: prostate cancer, testicular cancer, crashing sperm counts, infertility, and numerous developmental problems including cryptorchidism, urogenital malformations, and hypospadias. The report highlights pesticides, microplastics, phthalates, bisphenols, PFAS and heavy metals as the likely environmental sources of the crisis. There is evidence that all of these endocrine disrupting chemicals (EDCs) adversely affect male reproductive function.

Excerpts from the latest research on the drop in sperm counts globally and declines in male reproductive health, the science report from HEAL: Chemical pollution and men’s health: A hidden crisis in Europe

A 2023 meta-analysis by Levine et al. showed that global sperm counts declined by 52% between 1973 and 2018. European countries showed similar or even steeper declines, especially in Western and Southern Europe. ...continue reading "Male Sperm Counts Continue to Decline"

Chemicals of Concern Found In the Bodies of Young Children

SimaJuly 6, 2025July 6, 2025Leave a comment

Once again, those wondering about the chemicals lurking inside us have bad news. In a long-running study, researchers tested 201 young children (aged 2 to 4 years old) and found that all of them have many dangerous chemicals ("chemicals of concern") in their bodies. Some of the chemicals were in higher levels in the children than in their mothers during pregnancy.

In this study pregnant women from 4 states had their urine analyzed, and later the urine of their children when they were 2 to 4 years old. The testing of blood and urine from a person and looking for certain chemicals is called biomonitoring.

The researchers only looked for 111 chemicals and found that at least 5 children had 96 of them detected in their urine. Over 50% of the children had 48 chemicals detected. Thirty four of the chemicals were detected in over 90% of the children. But keep in mind that they only looked for a limited number of chemicals. Some of the chemicals found are not being monitored in adult biomonitoring. Many chemicals we are routinely exposed to, such as the common pesticide glyphosate (found in many non-organic foods) were not looked at.

One trend the researchers found is that levels of 2,4-D (pesticide used as a herbicide or weed-killer) are trending upwards over time. This is because 2,4-D is commonly used as a weed-killer on lawns (including Feed and Weed) and elsewhere, but it is also used on genetically modified crops.

The 111 chemicals tested for are from the foods and beverages children (and adults) ingest, personal care products (e.g., soap, lotion), the chemicals used in the home (e.g., pesticides, cleaning products) or chemicals outgassing from products used in the home (e.g., from non-stain synthetic rugs, plastic toys, vinyl floors). Children are exposed to the chemicals when they breathe indoor and outdoor air, eat food, touch surfaces or objects - both indoors and outdoors.

Bottom line: Eat as many organic foods as possible (pesticides such as 2,4-D and glyphosate are not allowed in organic food production). Additional tips: Lifestyle tips for avoiding harmful chemicals.

Excerpts from Science Daily: Researchers tested 200 toddlers — 96 chemicals were lurking in their bodies

A national study published in Environmental Science & Technology finds children aged 2 to 4 years in the United States are routinely exposed to a broad range of potentially harmful chemicals. Many of the chemicals the researchers identified are not routinely monitored and may pose health risks. ...continue reading "Chemicals of Concern Found In the Bodies of Young Children"

Health Effects From Titanium Dioxide In Foods

SimaJune 21, 2025June 23, 2025Leave a comment

Titanium dioxide nanoparticles Credit: Wikipedia

Titanium dioxide appears in many foods and some medicines (e.g., Allegra), in order to make colors and whites look brighter. In other words, it is an unnecessary food additive, found in a large variety of (ultra-processed) foods, including some candies, gum, frosting, soups, and even macaroni and cheese. It is allowed in the US (in over 11,000 food products!), but banned in Europe due to its harmful health effects.

A number of studies have linked titanium dioxide in its small nanoparticle form (between 1 and 100 nanometers) with a number of health harms, including to the gut (intestines). A recent study found that nanoparticle titanium dioxide has harmful or disruptive effects on the intestinal endocrine (hormone) system, resulting in abnormal blood sugar (glucose) levels, which can lead to insulin resistance and diabetes. It also caused intestinal lining changes, reduced levels of gut hormones, and resulted in a drop in enteroendocrine cells

Larger particles of titanium dioxide Credit: Wikipedia

While the study was done in mice, the results are also thought to apply to humans. The study didn't find the same health harms from larger titanium dioxide particles called microparticles (about the size of a fine grain of sand), but only from the nanoparticles. The problem is that nanoparticles are so small that once ingested, they get into cells and tissues throughout the body. However, large particles can be excreted from the body.

Bottom line: Unfortunately, it's the small nanoparticles that are so common in foods that we ingest. Read labels carefully and try to avoid those with titanium dioxide or artificial colors (includes titanium dioxide).

Excerpts from two informative articles: 1) From investigative journalism site US Right to Know: Tiny titanium dioxide particles in food raise blood sugar, disrupt gut hormones in mice, study finds

The study, published this month [May 2025] in Food and Chemical Toxicology, adds to growing concerns over the safety of titanium dioxide (TiO₂), a widely used color additive that is banned in the EU but widely used in the U.S. and elsewhere. It also highlights the food industry’s increasing use of microscopic materials to preserve or enhance foods. ...continue reading "Health Effects From Titanium Dioxide In Foods"

When Will Our Government Protect Us From Endocrine Disruptors and Harmful Pesticides?

SimaJanuary 22, 2025January 23, 2025Leave a comment

Over the course of the past decade, while reading many, many studies and articles about the FDA and EPA (you know, the government agencies meant to protect us) I have become cynical. And depressed. The agencies are not doing a good job protecting ordinary people (us), especially from endocrine disruptors and pesticides. There is too much corruption and too much money involved, with the bottom line being that Big Business is protected and does as it wants.

One example is why paraquat is still used in the US. This pesticide is a weed-killer that researchers link to a wide variety of diseases, including Parkinson's disease. It is widely used in the US, but banned in more than 70 countries. The EPA won't take action, and keeps saying the evidence for harms is "weak" and "insufficient", and they'll have to reassess the pesticide. But neuroscientists say:

“We know from animal work—and this is convincing and consistent—that paraquat isn’t safe,” says Bas Bloem, a neurologist at Radboud University Medical Center. The compound can pass from the bloodstream to the brain, he notes, and kills dopaminergic neurons, the loss of which drives Parkinson’s; indeed, paraquat is used to create laboratory animals with Parkinson-like disease. It also enhances the buildup of a misfolded, toxic version of the protein alpha-synuclein that’s a hallmark of the disease."

This relationship between Big Business (Big $$) was summed up by Dr. Theo Colborn back in 2014: “Our government operates via the stakeholder approach,” says (Theo) Colborn, “where those who are creating the problem are invited to solve the problem.” Yup.

Plastic duck containing endocrine disruptors

Theo Colborn was an absolutely amazing person. She is the main reason that endocrine disruptors are even being discussed these days. [Go read Our Stolen Future, published in 1997]. And, of course, Big Business (Big $$) went after her. But she (and others) persisted, and nowadays endocrine disruptors are taken very seriously by researchers and the general public.

Some good resources for up-to-date information about endocrine disruptors and pesticides: Collaborative About Health and the Environment (CHE) (up-to-date research, including research webinars), Silent Spring Institute, Environmental Working Group (EWG), PFAS Central, Beyond Pesticides (including their Daily News Blog), and Environmental Health News (EHN). ...continue reading "When Will Our Government Protect Us From Endocrine Disruptors and Harmful Pesticides?"

We’ve Known About the Harms of Endocrine Disruptors For Over 30 Years

SimaJanuary 10, 2025January 11, 2025Leave a comment

Book: Our Stolen Future

A few weeks ago was the 10th anniversary of the death of Dr. Theo Colborn. She was a pioneering giant that actually started the whole field of endocrine disruption from chemical pollutants in the environment.

It was due to her efforts that the term "endocrine disruption" (hormonal disrupting effects) was coined in 1991. Dr. Theo Colborn co-authored the groundbreaking 1996 book on endocrine disruptors: Our Stolen Future: Are We Threatening Our Fertility, Intelligence, and Survival? A Scientific Detective Story.

I read the book when it first came out, and my advice is to: YES - please read this book! It is absolutely worth it. By the way, one of the co-authors is Pete Myers, who is the founder of Environmental Health Sciences, which publishes Environmental Health News.

Unfortunately, even with all the knowledge we have about endocrine disruptors and the harms to humans and wildlife - they are still all around us, including personal care products (e.g., parabens in many lotions). Industry pushback is huge, of course.

Excerpts from Environmental Health News (EHN): Ten years after her passing, Theo Colborn's legacy continues to grow

Dr. Theo Colborn, who passed away December 14, 2014, was the founder of the endocrine disruption field, connecting the dots among the different health problems seen in wildlife with those seen in humans, tying them to the endocrine system and to chemical pollutants. ...continue reading "We’ve Known About the Harms of Endocrine Disruptors For Over 30 Years"

Many Household Items Contaminated With Flame Retardants

SimaNovember 8, 2024November 10, 2024Leave a comment

If you already suspected that we are surrounded by toxic chemicals in our homes - yes, your suspicions are true. A new study found that toxic flame retardants are in many household items that we use daily, specifically black plastic items (e.g., kitchen utensils, toys, takeout containers). That's because black plastic items tend to include recycled plastics.

In the study the researchers tested 230 store-bought items in the Seattle area for flame retardants, and found flame retardants in 85% of them. All the tested items were of black plastic or had black plastic somewhere in them (e.g., underside of toy cars). Showing that the flame retardants are pervasive, the 10 items with the highest levels of flame retardants were a sushi tray, toy car, peeler, travel checkers set, toy beads, and other kitchen utensils.

The problem with recycled plastics is that much of it comes from plastic that originally had flame retardants and other toxic chemicals added to it, for example electronics and electric products. When these recycled plastics are added to ordinary household items, the original toxic chemicals are in them, and now the consumer gets exposed to them. For example, in food utensils, toys, takeout containers, office supplies, and more. These items do NOT need flame retardants in them.

The study found that up to 2.3% of the weight of the household products were flame retardants. Some of the chemicals they found have been phased out, but are still winding up in recycled plastic. Studies show that flame retardants migrate from cooking utensils into food, and from toys into saliva. These chemicals are linked to cancers, endocrine and reproductive problems, and other health problems. Also, they tend to bioaccumulate in the environment and in people. Yikes!

Bottom line: At this point try to avoid black plastic items or items with some black plastic, especially in toys, food containers, and kitchen/household products. Right now view all "recycled plastic" items as problematic and to be avoided.

From Medical Xpress: From kitchenware to toys, household items linked to toxic flame retardants

From toys to kitchenware to food takeout trays, researchers have discovered a toxic chemical banned for its link to cancer in many common household items. Exposure to the flame retardant can come with serious health risks. ...continue reading "Many Household Items Contaminated With Flame Retardants"

Forever Chemicals Are Linked To Colorectal Cancer

SimaSeptember 28, 2024September 28, 2024Leave a comment

A number of things can contribute to the development of colorectal cancer (colon cancer), such as highly processed foods, eating a Western diet low in fiber, or the bacteria Fusobacterium nucleatum. These are known to contribute to or result in the gut microbiome being out of whack (gut dysbiosis).

Another factor is perfluorooctanesulfonic acid (PFOS), which are chemicals we all are exposed to in everyday life. A recent study illustrated how long-term exposure to PFOS can also contribute to the development of colorectal cancer because of the effect it has on intestinal cells in the intestines.

PFAS and PFOS (Per- and polyfluoroalkyl substances) are called forever chemicals due to their buildup (bioaccumulation) and persistence in people and the environment. We get exposure to these chemicals various ways - through ingestion (food and water), inhalation (dust), and from absorption through the skin (e.g., personal care products).

They are widely used chemicals, such as in non-stick coatings (e.g., pots and pans) and stain and water repellent products. We get exposure to these chemicals various ways - through ingestion (food and water), inhalation (dust), and from absorption through the skin (e.g., personal care products).

They are in all of us at varying levels, and they have harmful health effects. Effects include cancer, reproductive harm (e.g., poorer semen quality), birth defects, lowered sex and growth hormones in children, thyroid disease, immune effects, and liver and kidney damage. They are endocrine disruptors.

The chemical industry would have you think that the newer PFAS chemicals that replace the older ones are "safer", but guess what? They're not. They're very similar chemically, so it shouldn't be surprising that they don't appear to be safer.

Bottom line: You can't totally avoid PFAS chemicals, but you can lower your exposure to them. If possible, avoid products that are water and stain proof or leak-proof, especially if children will be using the product. Don't use nonstick cookware, stain resistant carpeting and fabrics, clothing treated to be water-proof, and synthetic turf. PFAS and PFOS don't have to be mentioned on labels, so it's buyer beware.

From Medical Xpress: Study links 'forever chemical' PFOS with colorectal cancer

A recent University of Kentucky Markey Cancer Center study sheds light on how the environmental pollutant perfluorooctanesulfonic acid (PFOS) may affect our intestines and possibly increase the risk of developing colorectal cancer. ...continue reading "Forever Chemicals Are Linked To Colorectal Cancer"

Microplastics Found In Human and Dog Testicles

SimaMay 30, 2024May 30, 2024Leave a comment

Scientists have been finding microplastics (tiny plastic particles) in our bodies - in our lungs, our blood, even our stools. The latest is a study finding microplastics in both human and dog testicles (in the testicular tissue). The small microplastics get into our bodies through inhalation and by ingestion (in the food and water), and from there they travel to different organs of the body.

They found 12 types of microplastics in all 23 human and 47 dog testicles that were studied. [NOTE: testicles = testes] In all of them! Human testicular tissue had 3 times the amount found in dogs.

They also found that higher numbers of PVC microplastics in the dog testicular tissue was correlated with a lower sperm count. (They were unable to test for this in the human samples.)

These concerning results may be part of the reason human sperm count is dropping rapidly worldwide over the past few decades. (These are thought to be contributors to the decline: pesticides, endocrine disruptors, heavy metals, plastics.) Microplastics, occur as a result of plastics breaking down, and are now found everywhere that researchers look.

From Science Daily: Researchers find microplastics in canine and human testicular tissue

University of New Mexico researchers have detected significant concentrations of microplastics in the testicular tissue of both humans and dogs, adding to growing concern about their possible effect on human reproductive health. ...continue reading "Microplastics Found In Human and Dog Testicles"

Forever Chemicals Can Enter and Accumulate In the Brain

SimaMay 17, 2024May 17, 2024Leave a comment

The toxic chemicals PFAS, commonly referred to as "forever chemicals" (due to their buildup and persistence in people and the environment) are in the news again. Once again, it's bad news. This time, researchers found that PFAS chemicals travel through the blood, and enter and accumulate in the human brain.

And not just the original PFAS chemicals (e.g., used in Teflon, Scotchgard), but even their replacements accumulate in the brain.

PFAS (Per- and polyfluoroalkyl substances) are called forever chemicals due to their buildup and persistence in people and the environment. They are in all of us at varying levels, and they have harmful health effects. Effects include cancer, reproductive harm (e.g., poorer semen quality), birth defects, lowered sex and growth hormones in children, thyroid disease, immune effects, and liver and kidney damage. They are endocrine disruptors.

Bottom line: You can't totally avoid PFAS chemicals, but you can lower your exposure to them. If possible, avoid products that are water and stain proof or leak-proof, especially if children will be using the product. Don't use nonstick cookware, stain resistant carpeting and fabrics, clothing treated to be water-proof, and synthetic turf. PFAS don't have to be mentioned on labels, so it's buyer beware.

From Environmental Health News: PFAS can enter and accumulate in the brain, study confirms

A new study published in Environment International examines the ability of PFAS - a class of hazardous chemicals with known neurotoxic effects - to bypass the body’s protective barriers and enter into brain tissue. ...continue reading "Forever Chemicals Can Enter and Accumulate In the Brain"