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It has been known for a while that getting a good night's sleep after getting vaccinated results in a stronger immune response. Twice as strong response! A recent study suggests that this could be due to beneficial T-cells (which are part of immune system) migrating toward the lymph nodes during sleep.

Growth hormone and prolactin are both involved in the migrating response.

Similarly, many studies find that having a short sleep duration (less than 6 hours) after a vaccination reduces the immune antibody response.

Bottom line: If you want a good antibody/immune response to a vaccine - get a good night's sleep of 6 or more hours after being vaccinated! Good sleep stimulates the immune system.

From Science Daily: Immunology: Good sleep stimulates the immune system

Sleep is healthy -- this popular knowledge is backed by science.

Previous research had already shown that in people who slept after a vaccination, the immune response was twice as strong on average as in people who did not sleep during the night after the vaccination. However, the cell biological reasons for this had been little investigated before now.

...continue reading "Get A Good Night’s Sleep After Getting Vaccinated"

Many of us do not get enough sleep at night. Unfortunately, this is bad for our health. Another large study just confirmed this - they found that consistently getting 5 or fewer hours per night during mid-life or later in life is linked to developing several diseases.

Sleeping 9 or more hours at 60 or 70 years of age (but not at age 50) was also associated with developing multiple chronic diseases. No association was found between sleep duration and early death among those with existing chronic diseases.

The study, conducted in the UK, looked at sleep amounts in more than 7000 persons over a 25 year span (when they were 50, 60, and 70 year old). Persons with short sleep duration (5 or fewer hours) had a higher risk of developing not just one chronic disease, but multiple chronic diseases.

The possible chronic diseases were: diabetes, cancer, coronary heart disease, stroke, heart failure, chronic obstructive pulmonary disease (COPD), chronic kidney disease, chronic liver disease, depression, dementia, mental disorders, Parkinson's disease, arthritis/rheumatoid arthritis.

From Science Daily: Five hours' sleep a night linked to higher risk of multiple diseases

Getting less than five hours of sleep in mid-to-late life could be linked to an increased risk of developing at least two chronic diseases, finds a new study led by UCL researchers. ...continue reading "Sleeping Less Than Five Hours A Night Ups the Risk For Health Problems"

So many of us seem to not get enough sleep, and then there are those that sleep and sleep. But .. it seems the sweet spot for sleep and our brain health (cognitive performance) is about 7 to 8 hours - at least according to a large study from Canadian researchers at Western University. People reporting typically sleeping 4 hours or less a night had the most impairments in how they performed on a variety of cognitive tests - equivalent to aging 8 years.

Reasoning, verbal skills, and overall cognition were impaired by less than 7 hours or more than 8 hours of sleep. But not short term memory. Actual age of the person made no difference on the results - everyone performed best at 7 to 8 hours of sleep. (Volunteers completed a series of 12 tests online which measured a broad range of cognitive abilities.) By the way, about half of the 10886 persons participating in the study reported typically sleeping 6.3 hours or less a night. Not enough. The good news is that just one night of sleeping a little more than the usual too little had a positive effect on cognitive abilities - thus cognitive improvement. From Science Daily:

World's largest sleep study shows too much shut-eye can be bad for your brain  ...continue reading "What Is Optimal Amount Of Sleep For Our Cognitive Processes?"

This is a nice study showing cause and effect:  6 hours of sleep or less at night lowers the body's resistance so that the person is more likely to catch a cold virus. From Science Daily:

Short sleepers are four times more likely to catch a cold

A new study led by a UC San Francisco sleep researcher supports what parents have been saying for centuries: to avoid getting sick, be sure to get enough sleep. The team, which included researchers at Carnegie Mellon University and University of Pittsburgh Medical Center, found that people who sleep six hours a night or less are four times more likely to catch a cold when exposed to the virus, compared to those who spend more than seven hours a night in slumber land.

Scientists have long known that sleep is important for our health, with poor sleep linked to chronic illnesses, disease susceptibility and even premature death. Prather's previous studies have shown that people who sleep fewer hours are less protected against illness after receiving a vaccine. Other studies have confirmed that sleep is among the factors that regulate T-cell levels.

Researchers recruited 164 volunteers from the Pittsburgh, PA, area between 2007 and 2011. The recruits underwent two months of health screenings, interviews and questionnaires to establish baselines for factors such as stress, temperament, and alcohol and cigarette use. The researchers also measured participants' normal sleep habits a week prior to administering the cold virus, using a watch-like sensor that measured the quality of sleep throughout the night.

The researchers then sequestered volunteers in a hotel, administered the cold virus via nasal drops and monitored them for a week, collecting daily mucus samples to see if the virus had taken hold. They found that subjects who had slept less than six hours a night the week before were 4.2 times more likely to catch the cold compared to those who got more than seven hours of sleep, and those who slept less than five hours were 4.5 times more likely.