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Month: March 2019

Published on Leave a comment on Walnuts Have An Effect On Breast Cancer Tumors

A very interesting, but very preliminary study just came out about breast cancer and walnuts. Could follow up research really show this to be true - that eating walnuts has an anti-breast cancer effect?? Animal studies find that multiple ingredients in walnuts (e.g.alpha linolenic acid, beta-sitosterol, a number of antioxidants such as ellagic acid) reduce the risk of cancer or slow its growth, or even increase tumor cell death. Researchers think this is true for human breast cancer also, and so a study was done looking at "gene expression" of breast cancer tumors. The question asked by the Marshall University (West Virginia) researchers was: Would eating 2 oz (14 halves) of walnuts daily for 2 to 3 weeks have an effect on the breast cancer tumors?

10 post-menopausal women had diagnostic breast cancer tumor biopsies done and then were randomly divided into 2 groups: 1) 5 of the women ate 2 oz of walnuts daily for the 2 to 3 weeks until breast cancer surgery, and 2) the other 5 avoided eating walnuts in the 2 to 3 weeks prior to breast cancer surgery. Otherwise the women ate their normal diets - a Western style diet.

The researchers noted that in the walnut eating group: "gene expression in the tumor was modified in ways expected to slow proliferation, reduce inflammation, reduce metastasis and to increase cancer cell death". The researchers also felt that consuming walnuts would decrease risk for cancer recurrence, and that there may be benefit from walnuts against many cancer types.

The researchers point out that another study published in 2016 (which was a review and analysis of 20 studies) concluded that "nut consumption, including peanuts, was associated with reduced risk of cancer and reduced all-cause mortality" (meaning death from any cause) - which agrees with the results of this study. In the 2016 study the beneficial health effect was for at least 28 grams (1 serving) of nuts per day. Bottom line: Enjoy consuming some nuts daily!

From Medical Xpress: Scientists tie walnuts to gene expressions related to breast cancer

New research from Marshall University links walnut consumption as a contributing factor that could suppress growth and survival of breast cancers.  ...continue reading "Walnuts Have An Effect On Breast Cancer Tumors"

Published on Leave a comment on What’s Getting Into You From Vinyl Flooring?

Many of us have concerns over the fact that people are constantly exposed to endocrine disruptors (chemicals that disrupt hormonal systems) in many common household and personal products. Even the vinyl flooring found in many homes  contains phthalates, which are endocrine disrupting chemicals.

In the past year several studies have looked at vinyl flooring in homes and whether the chemicals in the flooring outgas into the air and then get into people living in the homes. The answer is YES - the chemicals in vinyl flooring do get into people living there, and they can be measured in urine (in the breakdown products of phthalates called metabolites).

Since research shows that endocrine disrupting chemicals have health effects, then the question is: Do chronic low levels do anything to people? Especially worrisome is, are they having an effect on the developing fetus when pregnant women are exposed to them and they get into the body?

The following 2 studies looked at flooring, but keep in mind that we are exposed to phthalates in many, many products - e.g., plastic shower curtains, plastic food containers, some personal care products, household products. The problem is that the pthalates migrate out of the plastic products - they don't stay in the product. In the case of vinyl flooring - one can say that there are phthalate emissions from the flooring! And of course it gets into household dust.

Numerous studies found that phthalates (the phthalate metabolites) are routinely found in people of all ages - throughout the world. It can be measured in our blood (serum) and in our urine. Studies find them in breastmilk and also in amniotic fluid. Research finds associations associations between exposure to several phthalates and various effects on human health, including reproductive effects.

The following are two complementary studies. Study 1 looked at vinyl flooring (called PVC flooring in the article) in homes (in the kitchen and bedrooms), and found that phthalates get into pregnant women, and can be measured in the urine. Study 2 (from Duke University), found that chemicals children are exposed to in the home from vinyl flooring and the sofa (flame-retardants) can be measured in their blood and urine. The researchers took all sorts of samples from homes and children over a 3 year period and found evidence in the children of exposure to phthalates, organophosphate esters, brominated flame retardants, parabens, phenols, antibacterial agents and perfluoroalkyl and polyfluoroalkyl substances (PFAS).

So we have proof that these chemicals are getting into us. We can't avoid them totally, but can lower our exposure levels - look for upholstered furniture without flame retardants (read the label!), and don't install vinyl flooring (wood and tile floors are OK).  ...continue reading "What’s Getting Into You From Vinyl Flooring?"

Published on Leave a comment on Time To Stop Drinking Soda?

An interesting study found that high fructose corn syrup promotes the growth of intestinal tumors - in mice. The amount was fairly small - the equivalent of 12 oz of soda (with about 20 g of high fructose corn syrup) per day. The big question now: Is this also true for humans?

A number of studies find an association of soda consumption (which typically has high-fructose corn syrup in it), obesity,  and cancer (e.g. colorectal cancer) in humans, but the question remained whether this was due to obesity (obesity is linked to many types of cancer) or whether the high fructose corn syrup is directly contributing to tumor development or tumor growth. Based on the results of this study, the researchers felt that the high fructose corn syrup "enhances" or "promotes" intestinal tumor growth. Yikes.

From Science Daily: High-fructose corn syrup boosts intestinal tumor growth in mice

Does sugar directly feed cancers, boosting their growth? The answer seems to be 'Yes' at least in mice according to a study led by researchers at Baylor College of Medicine and Weill Cornell Medicine.  ...continue reading "Time To Stop Drinking Soda?"

Published on Leave a comment on Another Reason To Eat Nuts Frequently

Another study found benefits from eating nuts - this time an association between frequently eating nuts and better brain functioning in older adults. The study was done in China and was part of a long-term nutrition and cognitive function study of 4822 adults (aged 55+ years). With aging, it is normal to have some decline in brain functioning, but the researchers said that high nut consumers had much less decline - that the more nuts consumed, the less decline (an inverse relationship).

The article below makes some grand claims ("could improve their cognitive function by up to 60 per cent") for a study that found an association between long-term nut consumption of more than 10 grams (about 1/8 cup) daily and cognitive health, but this doesn't prove it. Perhaps people who eat nuts also eat other foods or do other things that are beneficial for brain functioning. But ... the good news is that eating nuts frequently appears to be beneficial. So eat and enjoy.

By the way, peanuts are not nuts - they are legumes (also beans and peas) - but they have numerous health benefits, and were counted as nuts in this study. Common tree nuts are cashews, almonds, walnuts, hazelnuts, pecans, macadamia nuts, pine nuts, pistachios, chestnuts, lichee nuts, and Brazil nuts. [See all posts on health benefits of nuts.]

From Science Daily: A nutty solution for improving brain health

Long-term, high nut consumption could be the key to better cognitive health in older people according to new research from the University of South Australia.  ...continue reading "Another Reason To Eat Nuts Frequently"

Published on Leave a comment on At What Age Do You Feel 65?

A recently published study attempted to compare countries to determine at what age does the average person feel like they are 65 years old - that is, at what age do they experience the typical health problems of a 65 year old (age-related diseases). We all generally want to live a healthy long life. But the reality is that most people will develop 1 or more health-related conditions or diseases as they age, with perhaps both physical and mental deterioration. The researchers looked at both among world countries - chronological age and the onset of age-related diseases and conditions (out of 92 conditions). As expected, when people have the health problems of an "average 65 year old" varies tremendously between countries.

The US didn't do so well: "At 68.5 years, the United States ranked 54th, between Iran (69.0 years) and Antigua and Barbuda (68.4 years)." Japan did the best - there 76 year olds have the same level of health problems as an "average" 65 year old. These findings match earlier research looking at worldwide populations, which found that no matter how long a person lives - about 1/8 of their life will be spent unhealthy or disabled, typically in the decade before death.

From Science Daily:  Wide variations in how well or poorly people age

A new study reveals wide variations in how well or poorly people age. A 30-year gap separates countries with the highest and lowest ages at which people experience the health problems of a 65-year-old, according to a new scientific study. Researchers found 76-year-olds in Japan and 46-year-olds in Papua New Guinea have the same level of age-related health problems as an 'average' person aged 65.  

These negative effects include impaired functions and loss of physical, mental, and cognitive abilities resulting from the 92 conditions analyzed, five of which are communicable and 81 non-communicable, along with six injuries. The studies and additional information are available at http://www.healthdata.org.   ...continue reading "At What Age Do You Feel 65?"

Published on Leave a comment on Controversies With the Prediabetes Diagnosis

Did you know that the issue of prediabetes and what it actually means for health is controversial among some physicians and medical groups? Elevated blood sugar was once considered a risk factor for type 2 diabetes, but now it has been elevated into a pre-disease called prediabetes. We are now told that 1 out of 3 Americans are pre-diabetic and 90 percent of us don’t even know it. The main issues are: What does a prediabetes diagnosis mean? Does prediabetes lead to diabetes? How frequently does this occur? Should one treat it with medications? When one thinks about risk factors - then they can usually be modified (e.g. diet, weight loss, exercise), but when something is called a pre-disease - then one thinks treatment (e.g. medicines).

Yes, we all agree that type 2 diabetes is a very serious health problem. But what about prediabetes? What is alarming to some researchers is that the definition of prediabetes has been broadened over the years to include millions more Americans. Also, what is considered prediabetes in the US may not be considered prediabetes in other countries. Keep in mind that the people most involved with promoting a broadening definition of prediabetes and promoting drugs to treat it, have a number of conflicts of interest (financial and scientific).

The site Health News Review covered the topic of prediabetes in Jan. 2017 in a post by Dr. Michael Joyce: BMJ:Can we trust the numbers that define pre-diabetes? Some quotes from that post: "...a meta-analysis of the progression rates of pre-diabetes shows the majority of people did NOT go on to develop diabetes a decade later."  "...in an article published in the BMJ, the accuracy of screening for pre-diabetes with fasting blood sugar and glycated hemoglobin is brought into question." ... “Our research looked at both these tests for pre-diabetes and found that neither of them was accurate,” says lead researcher Dr. Trisha Greenhalgh .... "In short, both our ability to predict diabetes with blood tests alone, and do so accurately in people with borderline elevated blood sugars, is questionable. Nonetheless, results from these tests – sometimes interpreted without clinical context – are being used to medicalize a risk factor and create a new medical condition."  Yikes!

This past week another thought-provoking article discussed the topic of prediabetes. Note that some experts call the focus on aggressively treating prediabetes as "scaremongering", especially because those promoting aggressive treatment the most are those with conflicts of interest. Centers for Disease Control and Prevention (CDC) data show that progression from prediabetes to diabetes is actually less than 10% in 5 years, and other studies show even slower (lower) rates. And a comprehensive 2018 Cochrane review of studies found that "up to 59% of prediabetes patients returned to normal glycemic values over 1 to 11 years with no treatment whatsoever". (see below) Wow! Excerpts from the article by Charles Piller in the journal Science:

Dubious Diagnosis

A war on "prediabetes" has created millions of new patients and a tempting opportunity for pharma. But how real is the condition?

The most common chronic disease after obesity, afflicting 84 million Americans and more than 1 billion people worldwide, was born as a public relations catchphrase. In 2001, the PR chief of the American Diabetes Association (ADA) approached Richard Kahn, then the group's chief scientific and medical officer, for help with a vexing problem, Kahn recalls. ADA needed a pitch to persuade complacent doctors and the public to take seriously a slight elevation in blood glucose, which might signal a heightened risk of type 2 diabetes. Raising the alarm wasn't easy, given the condition's abstruse name, impaired glucose tolerance, and lack of symptoms.  ...continue reading "Controversies With the Prediabetes Diagnosis"

Published on Leave a comment on Common Chemical Has Negative Effects On Sperm of Both Humans and Dogs

To the alarm of many, male fertility (sperm quality and sperm counts) has been rapidly declining over the past few decades. Researchers suspect that it's due to our exposure to chemicals in the environment, especially to endocrine disrupting chemicals - of which there are many, and to which we are exposed to daily. A recent study found that detrimental effects occur in the sperm of both humans and dogs when exposed to the common plastic softener DEHP and the persistent industrial chemical polychlorinated biphenyl 153 (PCB153). The researchers suggest this is because dogs live in households with humans and thus are exposed to the same environmental contaminants.

DEHP (diethylhexyl phthalate) is an endocrine disruptor (interferes with hormone systems) that is found in plastic materials in many household and personal items - for example, in carpets, vinyl flooring, some upholstery, rainwear, wires, some plastic toys, fragrances and air fresheners, some PVC pipes, some food packaging, medical tubing, plastic shower curtains. The problem is that it slowly leaches out of the products and into the air and household dust, it leaches out of packaging into foods (which we then ingest), and it can also be absorbed through direct skin contact. Bottom line: try to avoid DEHP by avoiding plastics known as polyvinyl chloride (PVC) or vinyl as much as possible. (One can't totally avoid them, but can reduce exposure to them.)

From Science Daily: Chemical pollutants in the home degrade fertility in both men and dogs, study finds

New research by scientists at the University of Nottingham suggests that environmental contaminants found in the home and diet have the same adverse effects on male fertility in both humans and in domestic dogs.  ...continue reading "Common Chemical Has Negative Effects On Sperm of Both Humans and Dogs"

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Published on 1 Comment on It Is Normal For Fungi To Be In Breast Milk

Researchers have known for a while that human breast milk contains hundreds of species of bacteria that a baby ingests while feeding. This is good! The bacteria is seeding the baby's gut microbiome (microbial community). A recent study of breast milk from different continents found that breast milk from healthy mothers also contains species of fungi - which is the breast milk mycobiome. What was noteworthy was that some  types of fungi in breast milk were found among breast milk samples from all locations (a fungi "core group"), while other types of fungi varied among breast milk from the different locations and even how the baby was delivered (vaginal or C-section birth).

After analyzing the 80 samples of breast milk (20 from each country: Spain, Finland, South Africa, China) it was found that some fungi were the same in breast milk from the different locations: Malassezia, Davidiella, Sistotrema, and Penicillium, while others were different. Fungi from the genus Cryptococcus were higher in breast milk from women who delivered vaginally (as compared to those who had a C-section).  [Note: Genus ranks above species, but below family, and the written name is capitalized.]

This study confirms the importance of breast milk as a source of microbes (along with many nutrients and protective compounds) to the infant and infant gut. From Science Daily:

Breast milk microbiome contains yeast and fungi: Do these benefit the infant?  ...continue reading "It Is Normal For Fungi To Be In Breast Milk"