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Author: Sima

Published on Leave a comment on Playing Outside In Nature Is Healthy For Young Children

To boost the immune system of young children, as well as improve their skin and gut microbiomes - send them out daily to play in a natural environment. That means outdoors in a natural park-like setting with grass, plants, soil, and trees. Yes, germs and dirt!

Finnish researchers found that replacing the gravel and pavement in urban daycare playground areas with natural forest-type vegetation (forest plants, shrubs, sod, mosses, and peat blocks for climbing) resulted in beneficial changes to young children's immune systems, and skin and gut microbiomes. This happened in just one month!

The researchers studied 75 children (3 to 5 years old) at 10 daycare centers in 2 Finnish cities (urban areas). Four of the daycare centers had their gravel/paved playgrounds turned into a forest-type natural area (where the children played), 3 daycare centers weren't changed (kept the gravel/pavement), and 3 daycare centers were already nature-oriented with children visiting forests daily. All children spent the same amount of time outside each day.

An important finding was that after 28 days the skin and gut microbiomes (microbial communities) of children playing in the transformed forest-type playgrounds had shifted to become more similar to children attending nature-oriented daycares. This change was also reflected in their immune systems: they developed a higher ratio of anti-inflammatory proteins to pro-inflammatory proteins in their blood (this is good).

The researchers point out that getting exposed to all the microbes in a natural forest-type setting (environmental microbial diversity) is beneficial. On the other hand, playing outside on man-made landscaping materials does not result in beneficial changes. Translation: playing outside in the dirt and plants is good for you.

From Medical Xpress: Replacing asphalt with forest-type plants at daycare centers found to strengthen immune defenses in children

A team of researchers affiliated with multiple institutions in Finland and one in the Czech Republic found that replacing asphalt in play areas at daycare centers with natural vegetation can lead to stronger immune defenses in the children at the centers. In their paper published in the journal Science Advances, the group describes removing asphalt from play areas at several daycare centers and replacing it with forest floor vegetation, and what they found when they tested the children who attended the centers.  ...continue reading "Playing Outside In Nature Is Healthy For Young Children"

Published on Leave a comment on New FDA Warning About Using Common Pain Relievers During Pregnancy

The US Food and Drug Administration (FDA) just issued a new warning about taking non-prescription and prescription pain relievers known as nonsteroidal anti-inflammatory agents (NSAIDS) during pregnancy. The FDA warned that using them from week 20 or later during pregnancy can cause rare, but serious, kidney complications in the unborn baby. This can lead to low levels of amniotic fluid (called oligohydramnios) surrounding the baby and possible complications.

The FDA advice is to avoid the following NSAIDs from week 20 and later of pregnancy: ibuprofen (Advil, Motrin), naproxen (Aleve), diclofenac, and celecoxib (Celebrex). However, low dose (81 mg) aspirin is excluded from this warning. [See FDA warning for more information.]

The FDA had earlier warned about those same NSAIDs - cautioning to avoid taking them during pregnancy after week 30 because of heart-related risks.

The full warning and information from US FDA: FDA recommends avoiding use of NSAIDs in pregnancy at 20 weeks or later because they can result in low amniotic fluid

Excerpts from Medscape: FDA Issues New NSAIDs Warning for Second Half of Pregnancy

The US Food and Drug Administration released new warnings today that most nonsteroidal anti-inflammatory agents (NSAIDs) carry an elevated risk for kidney complications in an unborn children when taken around weeks 20 or later in pregnancy.  ...continue reading "New FDA Warning About Using Common Pain Relievers During Pregnancy"

Published on Leave a comment on Wash Your Hands!

A study looked at how long the new coronavirus (SARS-CoV-2) which causes COVID-19 lives on human skin. Researchers in Japan used human cadaver skin (because they didn't want to infect living humans) to compare influenza and the new coronavirus. They found that coronavirus lives up to 9 hours on undisturbed skin! And influenza A virus (a flu strain) less than 2 hours.

They also found that both viruses are easily washed away with soap and water or a hand sanitizer containing 80% alcohol.

Yes, it is thought that aerosol and droplets are the main ways to get the new coronavirus. But you do want to wash it off your hands after exposure. Proper hand hygiene!

From Medscape: New Coronavirus Survives Nine Hours on Human Skin

Left undisturbed, the new coronavirus can survive many hours on human skin, a new study has found.  ...continue reading "Wash Your Hands!"

Published on Leave a comment on More Older Adults Are Using Cannabis Products For Medical Problems

What a change from a few decades ago when marijuana use was totally illegal, frowned upon, and viewed as a "gateway drug"! A recent study found that about 15% of older adults reported using cannabis in the past 3 years. Most adults (78%) reported they used it only it to treat medical problems such as pain or arthritis (73%), sleep disturbances, anxiety, and depression.

University of California researchers conducted anonymous surveys of 568 older adults aged 65 years and older at a geriatrics clinic in California. They found that adults using cannabis for the first time after the age of 60  were more likely to apply it topically as a lotion, and not by smoking it or ingesting it as edibles. Three fourths said the products helped them.

A minority used it for recreational purposes by smoking or eating edibles. About half (53%) of cannabis users reported using cannabis regularly on a daily or weekly basis. The researchers pointed out that other surveys at geriatric clinics also showed increased cannabis use in recent years.

From Science Daily: Older adults using cannabis to treat common health conditions

With growing interest in its potential health benefits and new legislation favoring legalization in more states, cannabis use is becoming more common among older adults.  ...continue reading "More Older Adults Are Using Cannabis Products For Medical Problems"

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Published on 1 Comment on Intermittent Fasting Study Didn’t Find Expected Health Benefits

Intermittent fasting has generated much excitement over its potential  as a simple method to lose weight and improve health. It involves eating normally  during limited hours each day (e.g. 8 hours), and then abstaining from food the other hours (e.g. 16 hours). However, a recent study found that people following intermittent fasting for 12 weeks did not really lose weight or improve key metabolic markers. Bummer.

University of California researchers randomly assigned 116 adults, who were overweight or obese, to either an intermittent fasting group (16 hours fasting/8 hours allowed to eat ) or a group that ate 3 regular meals at set times each day (breakfast, lunch, dinner). The intermittent fasting group lost 2 pounds over the 12 weeks, which is not significantly different from the group that ate their meals at structured times - they lost 1 1/2 pounds. Same with metabolic markers (e.g.insulin levels, fasting glucose levels, cholesterol levels) - no real differences between the groups after 12 weeks.

Of course this was just 1 study, so we'll see what other human studies find. In contrast, other small human studies, as well as mice studies, have found health benefits from intermittent fasting, also called time restricted eating.

From Medical Xpress: Intermittent fasting is popular—but it doesn't work for weight loss

The currently popular diet of intermittent fasting that restricts eating to eight hours per day, separated by 16 hours of fasting, is not effective on its own as a means of either losing weight or for improving key metabolic health markers, according to a new study led by researchers at UC San Francisco.  ...continue reading "Intermittent Fasting Study Didn’t Find Expected Health Benefits"

Published on Leave a comment on Introducing Gluten At 4 Months Of Age May Prevent Celiac Disease In Children
Weetabix biscuits Credit: Wikipedia

Exciting research from the UK suggests that to prevent celiac disease in children, the answer may be to feed the child gluten in early childhood (starting at 4 months of age). Early exposure!

Celiac disease, which occurs in about 1 in 100 people, is a lifelong condition caused by an abnormal reaction to gluten - a protein found in wheat, barley and rye. Eating gluten results in the body mounting an immune response that attacks and damages the small intestine, so that nutrients cannot be absorbed properly into the body. The only treatment for celiac disease is to strictly adhere to a gluten free diet.

The study included one group of children that had early exposure to high doses of gluten starting at 4 months (4 grams of wheat protein per week in the form of 2 Weetabix biscuits - wheat biscuits produced in the UK). They were compared to children who did not have gluten exposure until 6 months (standard dietary recommendations of breast milk only). At three years of age none of the early gluten group (0 out of 488 children) had celiac disease, while 1.4% (7 of 516 children) of the delayed gluten exposure had celiac disease.

This finding is along the lines of research suggesting that to prevent peanut allergies from developing feed small amounts of pureed peanut products (such as peanut butter or peanut puffs) to a child in the first year of life, starting as early as 4 months of age.

Another bit of interesting celiac disease research from 2019 found a link with higher fiber intake by the mother during pregnancy, especially of fruits and vegetables, and a lower incidence of celiac disease in the children. Also, gluten intake (high or low) by the pregnant woman had no effect on whether her child would later develop celiac disease.

From Science Daily: Early introduction of gluten may prevent celiac disease in children, study finds

Introducing high doses of gluten from four months of age into infants' diets could prevent them from developing celiac disease, a study has found. 
...continue reading "Introducing Gluten At 4 Months Of Age May Prevent Celiac Disease In Children"

Published on Leave a comment on Masks Protect Us Several Ways From the Coronavirus

Today while waiting in a line at the store, everyone wearing the required masks, the woman in front of me told me that the masks are useless and that there isn't good evidence that the coronavirus is spread through the air. Huh? Where did she get that idea? Of course there is airborne transmission of the virus!

It's true that some government agencies are hedging about airborne transmission of SARS-CoV-2 (the virus which leads to COVID-19 infection) , but the scientific evidence for aerosol and droplet transmission of the virus is growing and very clear. [Aerosols are smaller than droplets, and both carry the virus.] Fortunately, the evidence just isn't there for getting this particular virus from touching surfaces (such as doorknobs or faucets) - which originally was a big worry.

The following are some articles that discuss how airborne transmission occurs, why wearing a mask protects us from others exhaling the virus, and also protects us from inhaling the virus and lowers how much virus we are exposed to (cloth and surgical masks protect us from most virus particles, but not all). In fact, some scientists are wondering whether wearing masks so lowers the amount of virus a person is exposed to (viral load), that if a person gets the infection, the body can deal with it much better and the infections may be asymptomatic or minor.

In case you're wondering: being outdoors dilutes and disperses the virus. If you are concerned about the virus spreading indoors - then open a window (to dilute and disperse the virus).

This is a really big deal - the possibility that up to 95% of infections could be asymptomatic! Excerpts from an interesting article by Dr. Monica Gandhi (Prof. of Medicine at Univ. of California) at The Conversation: Cloth masks do protect the wearer – breathing in less coronavirus means you get less sick

It seems people get less sick if they wear a mask.   ...continue reading "Masks Protect Us Several Ways From the Coronavirus"

Published on Leave a comment on Some Intense Exercise Is Beneficial For The Brain

Exercise is good for memory and the brain. University of Geneva researchers found that even one short bout of moderate or intense exercise improves memory and acquisition of new motor skills.

In a well-designed study, 15 healthy volunteers exercised intensely for 15 minutes, moderately for 30 minutes, or rested, and were given various tests both before and after exercising. They found that exercise had beneficial effects on the hippocampus of the brain, and that physical exercise improves some types of memory. The hippocampus plays a critical role in learning and memory.

Intense physical exercise improves memory functions by increasing neural plasticity in the hippocampus. [Note: increasing plasticity of the brain is good.] The findings of this study match earlier animal research, in that "a single session of physical exercise has been shown to boost anandamide (AEA), an endocannabinoid known to promote hippocampal plasticity".

The researchers felt that this study provided additional evidence that physical exercise could possibly prevent cognitive decline as people age. Typically some cognitive decline, along with a reduction in brain volume, occurs in the aging brain, so slowing down or preventing cognitive decline is desirable. Bottom line: Get out and move, move, move for brain health! By the way, all physical activity is better than no activity.

From Medical Xpress: Sport and memory go hand in hand

If sport is good for the body, it also seems to be good for the brain. By evaluating memory performance following a sport session, neuroscientists from the University of Geneva (UNIGE) demonstrate that an intensive physical exercise session as short as 15 minutes on a bicycle improves memory, including the acquisition of new motor skills. ...continue reading "Some Intense Exercise Is Beneficial For The Brain"

Published on Leave a comment on Drinking Coffee Appears To Be Beneficial For Those With Colon Cancer

Another health benefit of coffee! A study found that daily consumption of a few cups of coffee was associated with longer survival and a lower risk of cancer worsening in persons with metastatic colon cancer. These benefits held for both caffeinated and decaffeinated coffee. This is a big deal because metastatic colon (colorectal) cancer only has a 5 year survival rate of 14%.

A group of researchers throughout the US found that in 1171 patients being treated for metastatic colorectal cancer, those who reported drinking 2 to 3 cups of coffee a day were more likely to live longer, and had a longer time before their disease worsened - as compared to people who didn't drink coffee. And those drinking more than 4 cups a day (either decaf or regular) had even greater benefits.

Coffee's benefits may be due to its ability to decrease blood insulin levels (it increases insulin sensitivity of tissues), as well as the chemical compounds in coffee having antioxidant, anti-inflammatory, and antiangiogenic(anti-blood vessel growth in tumors) effects. It appears that many of the beneficial effects appear to be not from caffeine, but from the chemical compounds in coffee. [Note: avoid caffeinated coffee during pregnancy - then it is linked to health problems.]

By the way, there are many studies showing that colon cancer is linked to diet and lifestyle. Best is to eat a diet rich in fruits, vegetables, whole grains, nuts, seeds, and legumes (beans, lentils). One especially eye-opening study compared the effects of an American high-fat, low fiber diet with a typical low-fat, high fiber diet of South Africa - and found dramatic changes in the colon (specifically in the colonic mucosa) from dietary changes in as little as 2 weeks. Their conclusion: Fiber feeds beneficial microbes in the gut, which results in beneficial changes in the gut (in the mucosa of the colon).

Excerpts from Medical Xpress: Coffee associated with improved survival in metastatic colorectal cancer patients

In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Dana-Farber Cancer Institute and other organizations report in a new study. ...continue reading "Drinking Coffee Appears To Be Beneficial For Those With Colon Cancer"

Published on Leave a comment on Vitamin D and COVID-19

Several studies are now suggesting that low vitamin D levels are linked to increased risk of getting COVID-19. And if you get COVID-19, low vitamin D levels are linked to a higher risk of developing serious symptoms requiring admission to intensive care,  and also not surviving. These studies are observational and don't prove that vitamin D levels are the cause, but a number of studies from countries worldwide and several lines of research are suggesting the same thing.

The best source of vitamin D is sunlight, but if taking supplements - then take vitamin D3. Researchers, doctors, and medical organizations vary in their recommended dosages, but many (such as Mayo Clinic) suggest 1000 to 2000 IU per day. The minimum daily requirement is 600 IU.

Some studies also suggest that having adequate magnesium is needed for vitamin D to be metabolized well. Good food sources of magnesium are nuts, seeds (especially pumpkin seeds), peanut butter, whole grains, beans, leafy vegetables, some fatty fish (halibut, salmon, mackerel), milk, yogurt, dark chocolate, legumes (beans), quinoa, tofu, and bananas. Daily magnesium requirements are 420 mg for men, 320 mg for women. Food is generally considered a better source than supplements.

However, some researchers point out that having a disease (e.g. diabetes) or chronic inflammation results in lowering of vitamin D levels (and not that low vitamin D levels causes disease). We need good double-blind studies (people randomly assigned to groups, and no one knows who is getting what) to understand if it really is vitamin D that's causing beneficial health effects.

Excerpts from Medscape: Low Vitamin D in COVID-19 Predicts ICU Admission, Poor Survival

Having low serum vitamin D levels was an independent risk factor for having symptomatic COVID-19 with respiratory distress requiring admission to intensive care — as opposed to having mild COVID-19 — and for not surviving, in a new study from Italy. ...continue reading "Vitamin D and COVID-19"