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scale, weightThe microbes in your mouth may offer a clue to obesity. New research finds that individuals with obesity have more of certain types of bacteria in their mouth. These bacteria, such as Streptococcus parasanguinis and Actinomyces oris, are proinflammatory - meaning they trigger inflammation in the body.

The community of microbes in the mouth is the oral microbiome. The oral microbiome is the second largest microbial ecosystem in the human body after the gut.

The researchers studied 192 individuals and found that not only is the diversity (variety) of oral microbes different in obese individuals, but also the composition of their microbes is different (when compared to healthy persons of normal weight). The oral microbiome is obese individuals was imbalanced (dysbiosis).

They found that overweight individuals also have higher numbers of microbes that produce lactate. High levels of lactate are associated with an increased risk of type 2 diabetes and poor metabolism. The researchers summarize why these microbial differences are important:

"Compounds generated by oral microbes can interact locally with oral tissues or enter circulation, triggering various signaling mechanisms in distant organs. Lifestyle factors, such as diet, smoking, oral hygiene, and antibiotic use, can shape oral microbiome composition. Emerging evidence links oral dysbiosis to several metabolic diseases, including obesity."

Bottom line: Try improving your diet, brushing your teeth, and not smoking to improve your oral microbiome.

From Medical Xpress: Microbes living in our mouths could hold the key to obesity prevention

Scientists may have found a new way to spot early signs of obesity, which could lead to novel prevention strategies. A study published in the journal Cell Reports has discovered that people living with obesity have a distinct set of microbes in their mouths compared to people at a healthy weight. ...continue reading "The Microbes In the Mouth and Obesity"

Very depressing news. The EPA plans to NOT take into account of the value of human life any more when making rules and setting policy regarding air pollutants (e.g., fine particulate matter and ozone). Meaning that the value of a human life is zero dollars. Instead, the only thing that will be considered is the cost to businesses of pollution regulations.

In other words, no more estimates of the dollar value of lives saved in the cost-benefit analyses for new pollution rules. People dying will just be a side-effect of business - eh, move on, nothing to see here.

This means that the cost to society (of human suffering and deaths) from pollutants just doesn't matter. Businesses obviously do not/will not want regulations that cost money.  Yes, this will mean dirtier air and the environment going forward. Very depressing...

Excerpts from NY Times: Trump’s E.P.A. Has Put a Value on Human Life: Zero Dollars

Government officials have long grappled with a question that seems like the purview of philosophers: What is the value of a human life?

Under both Democratic and Republican administrations, the answer has been in the millions of dollars. The higher the value, the more the government has required businesses to spend on their operations to prevent a single death.

But for the first time ever, at the Environmental Protection Agency the answer is effectively zero dollars. ...continue reading "The EPA Now Values Human Life At Zero Dollars"

Processed meat contains preservatives. Credit: Wikipedia

Once again, preservatives found in ultra-processed foods are linked to health harms. A large study of 105,260 French adults found that higher intakes of some common food additives or preservatives are linked to certain cancers.

There was an association of higher intake of seven preservatives with a higher risk of overall cancer, and also with breast and prostate cancer. On the other hand, there was no link between overall preservatives and cancer - just with the 7 preservatives.

The researchers looked at the overall cancer rate, as well as the most common 17 preservatives, and found certain associations:  potassium sorbate with overall cancer and breast cancer, potassium metabisulfite with overall cancer and breast cancer, sodium nitrite with prostate cancer, potassium nitrate with overall cancer and breast cancer, acetates with overall cancer and breast cancer, acetic acid with overall cancer, and sodium erythorbate with overall cancer and breast cancer.

Bottom line: Read ingredient lists on food labels. Avoid foods that contain ingredients with chemical sounding names that are not normally found in a home kitchen. Those ingredients are in ultra-processed foods. Additionally, "natural flavors" are laboratory concoctions (found in ultra-processed foods).

From The Guardian: Studies link some food preservatives to higher diabetes and cancer risk

Higher consumption of some food preservatives is associated with an increased risk of type 2 diabetes and cancer, two studies suggest.

The findings, published in the medical journals Nature Communications and the BMJ, may have important public health implications given the ubiquitous use of these additives globally, researchers said. ...continue reading "Some Food Preservatives Are Linked To Cancer"

Processed meat Credit: Wikipedia

Many studies are finding that eating ultra-processed foods (UPFs) can lead to all sorts of health problems. A recent large study conducted in France found that people eating higher amounts of food preservatives had a higher risk of type 2 diabetes. Overall, people consuming foods with higher amounts of preservatives had a 47% higher risk of developing type 2 diabetes (when compared to people eating low amounts of preservatives).

Over 100,000 French adults were followed for more than a decade. The researchers found that 58 preservatives were in the foods they ate. The researchers examined 17 preservatives in depth (the most common ones eaten) and found that 12 preservatives are linked to type 2 diabetes: potassium sorbate, potassium metabisulphite, sodium nitrite, acetic acid, sodium acetates, calcium propionate, sodium ascorbate, alpha-tocopherol, sodium erythorbate, citric acid, phosphoric acid, and rosemary extracts.

Bottom line: Read ingredient lists on food labels. Avoid foods that contain ingredients with chemical sounding names that are not normally found in a home kitchen. Those ingredients are in ultra-processed foods. Additionally, "natural flavors" are laboratory concoctions (found in ultra-processed foods).

From Science Daily: Common food preservatives linked to higher risk of type 2 diabetes

People who consume higher amounts of food preservatives may face a greater risk of developing type 2 diabetes, according to a large new study. Preservatives are commonly added to processed foods and beverages to extend shelf life. ...continue reading "Food Preservatives Linked to Higher Risk of Type 2 Diabetes"

There has been discussion over the years regarding mouthwash - what are the harms and benefits? Does using mouthwash regularly disrupt the oral (mouth) microbiome? Chlorhexidine mouthwash is generally considered the best for treating gingivitis and killing bacteria.

Researchers at the College of Dental Medicine, Univ. of Sharjah in the UAE, recently published a review of studies comparing garlic extract mouthwash vs chlorhexidine mouthwash. They found that garlic mouthwash can be as effective as chlorhexidine mouthwash.

Garlic (Allium sativum) has natural antimicrobial properties. The researchers found that among the studies there were some differences in effectiveness for both types of mouthwash depending on the concentration used and duration of application.

However, one negative they found is that garlic mouthwash can be more uncomfortable to use - it can cause a burning sensation and unpleasant taste.

Excerpts from Science Daily: Garlic mouthwash shows shockingly strong germ-fighting power

Garlic extract has been found to offer antimicrobial effects that are on par with commonly used antiseptics and disinfectants such as chlorhexidine, according to medical researchers at the University of Sharjah.

The study, published in the Journal of Herbal Medicine, reports that garlic-based mouthwash may produce more discomfort than chlorhexidine but appears to provide longer-lasting residual activity.

...continue reading "Garlic Extract Mouthwash Appears Promising"

The health benefits of regularly drinking coffee keep increasing. A recent study confirmed that consuming coffee on a regular basis reduces the incidence of liver disease and slows the progression of several liver diseases.

The study authors write that coffee contains a number of bioactive compounds (e.g., caffeine, polyphenols, diterpenes) which have "anti-inflammatory, antioxidant, antifibrotic, and anticancer properties".

In other words, enjoy your daily coffee. It's good for you!

Excerpts from Medscape: Regular Coffee Drinking Can Protect and Restore Liver Health

TOPLINE: Several bioactive compounds in coffee exert antioxidant, anti-inflammatory, antifibrotic, and metabolic effects that reduce the incidence and progression of liver diseases. ...continue reading "Coffee and Liver Health"

Natural hair, not straightened Credit: Wikipedia

For a few years there have been reports and research of hair straightening chemicals causing health harms, specifically kidney damage. Even kidney failure. Yet the use of these dangerous products continues in a number of countries, including the US, France, and Israel.

The problem appears to be the glyoxylic acid in some hair-straightening products. Bottom line: Read the ingredient lists on hair straightening products and avoid those with glyoxylic acid.

Excerpts from The Times of Israel: 17-year-old girl hospitalized for kidney failure after hair-straightening treatment

A 17-year-old girl who underwent a hair-straightening treatment was hospitalized with severe kidney failure at Shaare Zedek Medical Center, the hospital reports.

Another woman, 25, also suffered from kidney failure caused by hair straightening a little over a month ago. ...continue reading "Hair Straighteners Continue to Cause Kidney Harm"

Great news for cheese lovers! A recent study found regularly eating full-fat (high-fat) cheese and cream was associated with a lower risk of developing dementia. Some examples of full-fat cheese include cheddar, Swiss, Parmesan, Brie, Gouda, Provolone, Colby, Havarti, Mozzarella (full-fat), and cream cheese.

This was a long-running study (27,670 persons for 25 years) conducted in Sweden. High-fat cream and cheese consumption was inversely associated with dementia, Alzheimer's disease, and vascular dementia. Eating more than 50 grams (about 1/3 cup or 2 slices) of full-fat cheese per day was associated with a 13% to 17% lower risk of Alzheimer's, and more than 20 grams (about 1 1/2 tablespoons) of full-fat cream was linked to a 16% lower risk of dementia overall.

However, consumption of low-fat cheese, low-fat cream, milk (low or high fat), and butter showed no association with dementia.

From Science Daily: Study links full-fat cheese to lower dementia risk

...continue reading "High Fat Cheese and Lower Risk of Dementia"

It turns out that wearing silicone wristbands is a great way to measure a person's exposure to pesticides that are inhaled or absorbed in the skin - whether you are  farmer, living near pesticide treated farm fields, a pet owner, or a member of the general population (consumer). Another source of pesticides is food and water, but the silicone wristbands don't measure that.

A recent European study, using the silicone wristbands, found that conventional (non-organic) farmers are exposed to the greatest number and concentration of pesticides, followed by organic farmers and farm neighbors, and the fewest in ordinary consumers (the general population). The wristbands revealed that pesticide use, whether as a farmer or in the home, and having pets predicted greater pesticide exposure.

The researchers looked for the presence of 193 pesticides and found 172 of them. People are typically exposed to mixtures of pesticides. Keep in mind that many pesticides banned in the European Union are not banned in the US, and are routinely used in the US.

Pesticide use, whether as a conventional farmer or in the home, and having pets predicted a greater pesticide exposure. Organic farmers had  lower levels of pesticides, and were exposed to fewer pesticides than conventional (non-organic) farmers. This is because organic farmers are not allowed to use the many pesticides that are routinely used by conventional (non-organic) farmers.

A nice summary of the research from Beyond Pesticides: Lower Pesticide Exposure Documented For Organic Farmers, Elevated For Others

Published in Environment International, a study utilizing silicone wristbands provides a snapshot of chemical exposure in over 600 participants across 10 European countries. Using the wristbands as passive and noninvasive samplers, the researchers find that organic farmers’ wristbands contain lower pesticide levels than other groups, offering insight into the benefits of organic and disproportionate risks to farmers using chemical-intensive methods. The results further reveal prevalent environmental pesticide mixtures, in addition to highlighting exposure to current-use pesticides (CUPs) and legacy (banned) pesticides that occurs through multiple exposure routes to workers, residents, and consumers. ...continue reading "Pesticide Exposure Greater In Conventional Farmers Than Organic Farmers"

Upholstered sofa Credit: Wikimedia Commons

Worried about being exposed for years to sofas filled with flame retardants? The dust from the foam in these sofas release flame retardants into the air, which then get into people's bodies. Flame retardants are linked to all sorts of health problems (cancer risk, hormone disruption, and neurodevelopmental effects). But finally, there is some good news.

A recent study found that just one year after getting rid of old flame retardant filled sofas and chairs (and replacing them with flame retardant-free furniture) resulted in a huge decline in flame retardant polybrominated diphenyl ethers (PBDEs) in the body. The levels of PBDEs declined in half in 1.4 years.

The use of use of organophosphate flame retardants (OPFRs) in foam products (e.g., the foam in upholstered furniture) is also declining in upholstered furniture, but the levels in the study participants didn't decline as much. This is perhaps because OPFRs are still used today in many other products (e.g., as a plasticizer, a coating for electronic devices, in car furnishings).

Bottom line: When buying new sofas and upholstered chairs, look for flame-retardant free furniture. A label commonly on the bottom of the furniture will tell you if they contain flame retardant chemicals or not. [NOTE: Upholstered furniture made between 1970 and 2014 probably contains flame retardants.] Also, wash hands before eating. Vacuum with a HEPA filter.

From Medical Xpress: Swapping old sofas and chairs reduces body levels of harmful flame retardants

New research led by the California Department of Public Health and partners has found that replacing foam-containing furniture made before 2014 would cut in half levels of certain harmful flame retardants in people's bodies in just over a year.

Published in Environmental Pollution, the study is the first to show measurable health benefits from California's 2014 furniture flammability standard update, which made it possible for manufacturers to comply without adding chemical flame retardants. ...continue reading "Flame Retardant Levels In the Body Go Down When Old Sofas Are Replaced"