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Category: brain

Published on Leave a comment on Smoking and Shrinking of the Brain

We all know cigarette smoking is bad for our health (for example, higher rates of heart disease, respiratory disease, and cancer), but it also has an effect on our brains. Yup. Research shows it's associated with a decrease in brain size (volume)!

The researchers found that while all levels of daily smoking was associated with a decrease in brain volume, heavy smoking was associated with an even greater decrease in brain size (volume). This is a dose-response relationship.

By the way, this strong association between a history of daily smoking and overall brain volume, gray matter volume, and white matter volume of the brain was also found in other studies.

They also found that even if you stop smoking, you don't get back that missing brain volume. But at least it'll stop further cigarette smoking shrinkage. The researchers point out that this could explain why smoking is linked to increased rates of age-related cognitive decline and Alzheimer's. Yikes!

From Science Daily: Smoking causes brain shrinkage, study finds

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis. The good news is that quitting smoking prevents further loss of brain tissue -- but still, stopping smoking doesn't restore the brain to its original size. Since people's brains naturally lose volume with age, smoking effectively causes the brain to age prematurely, the researchers said. ...continue reading "Smoking and Shrinking of the Brain"

Published on Leave a comment on ADHD Medications and Increased Risk of Heart Disease

Many children and adults have been diagnosed with ADHD (attention deficit hyperactivity disorder) and been prescribed medications as a result. Medications that are taken daily for years. The big question is: Are there long-term health effects from ADHD medications?

A large study looking at long-term use of ADHD medications found an increase in cardiovascular disease, particularly hypertension and arterial disease, when compared to persons with ADHD who did not take medications. The longer the medications were taken, the higher the risk for hypertension and arterial disease.

In the 14 year follow-up, the researchers found that each 1 year increase of ADHD medication was associated with a 4% increased risk of heart disease (cardiovascular disease). The risk was higher for stimulant medications (e.g., methylphenidate, lisdexamfetamine) than for non-stimulant medications.

From Medical Xpress: Long-term ADHD medication use associated with increased cardiovascular disease

Research led by the Karolinska Institutet, Sweden, has found an increased risk of cardiovascular disease associated with long-term ADHD ( attention-deficit/hyperactivity disorder) medication use. Specific associations with different medications and dosages were connected to hypertension and arterial disease, with a higher risk observed for stimulant medications. ...continue reading "ADHD Medications and Increased Risk of Heart Disease"

Published on Leave a comment on Chronic Wasting Disease Now Detected in Yellowstone Park

Unfortunately, chronic wasting disease (CWD) is continuing to slowly spread through the United States and Canada. It has now been confirmed that a mule deer died of CWD in Yellowstone Park last month.

Chronic wasting disease has been slowly spreading in mule deer and elk in Wyoming since first detected in1985. It has been detected in 30 states so far!

CWD is a prion disease that can occcur in cervids (deer, elk, moose, reindeer) similar to "mad cow disease" (bovine spongiform encephalopathy) in cattle and Creutzfeldt-Jakob's disease in humans. It is an always fatal neurologic disease . There is no vaccine, treatment, or cure for the disease.

CWD should be of concern to all hunters or people who eat wild-caught game (deer, elk, moose, reindeer). So far no infections have been found in humans, but health officials urge hunters to test killed deer and elk for the disease, and to avoid eating meat from infected animals.

Excerpts from the National Park Service Nov. 15 news release: Mule deer tests positive for chronic wasting disease in Yellowstone National Park

 Yellowstone National Park and the Wyoming Game and Fish Department (WGFD) recently confirmed the presence of chronic wasting disease (CWD) in the carcass of an adult mule deer buck found near Yellowstone Lake in the southeastern section of the park. This is the first confirmed positive detection of the disease in Yellowstone National Park. ...continue reading "Chronic Wasting Disease Now Detected in Yellowstone Park"

Published on Leave a comment on The Case For Some Toxic Chemicals Causing Parkinson’s Disease

For years research has linked some pesticides and toxic chemicals with the development of Parkinson's disease. Recent research from the military base Camp Lejeune strongly suggests that one possible cause of PD is the toxic chemical trichloroethylene (TCE). The drinking water at Camp Lejeune was contaminated with high levels of TCE and perchloroethylene (PCE) for 35 years at 280 times safety standards.

In the past century, TCE (and the similar chemical PCE) has had numerous industrial, consumer, military, and medical applications. For example, it is used in dry cleaning clothes, removing paint, as a degreaser, carpet cleaner, and engine cleaner. It even was used to produce  decaffeinated coffee in the past! It's still used today - much less in the US, but increasing in China.

The problem is that TCE is environmentally persistent, and contaminates soil, air, and water. Vapors from underground water and soil contamination seep out into homes, schools, and workplaces. It is known to be carcinogenic (cancer causing) and associated with numerous cancers and other health harms, including birth defects.

The neurologist Ray Dorsey (at Univ. of Rochester), who was part of a team looking at TCE and Parkinson's disease (see post), was recently interviewed about the research linking TCE and PD. One finding: there has been a major increase in Parkinson's disease in the past decades, making it the "world's fastest-growing brain disease".

What you can do: Dr. Ray Dorsey (and fellow researchers) feel that PD is preventable. (their book). He recommends that everyone, but especially all persons with Parkinson's disease, try to avoid pesticides as much as possible. For example, use a carbon filter for drinking water, eat organic foods, don't put pesticides on the lawn, etc.

Excerpts from Dr. Subramanian (Professor at UCLA) interview with Dr. Ray Dorsey, from the medical site Medscape: Is Most Parkinson's Disease Man-Made and Therefore Preventable?

Subramanian: I wanted to first highlight some of the work that has come out and gotten a large amount of media attention around Camp Lejeune and specifically trichloroethylene (TCE) as a cause of Parkinson's, and one of the environmental toxins that we talk about as something that is in pretty much everywhere. This paper came out, and you wrote a commentary in JAMA Neurology as well. Perhaps we can summarize the paper and its findings. ...continue reading "The Case For Some Toxic Chemicals Causing Parkinson’s Disease"

Published on Leave a comment on Commonly Used Pesticides and the Adolescent Brain

Once again a study looked at pesticide exposure in humans and found health problems. This time a study by Univ. Of California researchers looked at exposures to the commonly used pesticides 2,4-D and glyphosate, and found that they are associated with neurobehavioral effects in teenagers.

Neurobehavioral effects means there are effects on the relationship between the brain and nervous system and behavior. The study found that 2,4-D had significant effects on brain function - with lower performance on tests measuring attention and inhibition control, language, memory/learning, and visual-spatial processing, while glyphosate had effects on social perception.

Studies finding harmful health effects from both of these pesticides (e.g., cancer, neurological effects, endocrine disrupting effects) are increasing each year.

By the way, almost all of us have the herbicide glyphosate (found in Roundup) in our bodies. Most of us also have 2,4-D residues in our bodies because of its common use as a weed-killer, especially in Feed and Weed products (used on lawns) and in crops.

We get pesticides into our bodies through the foods we eat and drink, air we breathe, and skin contact. Pesticide exposure to glyphosate and 2,4-D is actually increasing due to the increased use in genetically modified (e.g., Roundup Ready) crops and "preharvest" use in conventional crops.

Bottom line: Try to lower your exposure to pesticides. Eat organic foods as much as possible. (Glyphosate and 2,4-D are not allowed in organic food production.) Avoid using pesticides on your lawn. Use least toxic Integrated Pest Management for control of pests indoors and outdoors. Leave your shoes at the door.

From Medical Xpress: Research suggests commonly-used herbicide is harmful to adolescent brain function

Herbicides are the most used class of pesticides worldwide, with uses in agriculture, homes and industry. Exposures to two of the most popular herbicides were associated with worse brain function among adolescents, according to a study led by researchers at the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego. ...continue reading "Commonly Used Pesticides and the Adolescent Brain"

Published on Leave a comment on Routine Vaccines Associated With A Reduced Risk of Developing Alzheimer’s Disease

Great news! A recent study found that older adults who get routine vaccinations have a  lower risk of developing Alzheimer's disease and related dementias. Other studies looking at adults over the age of 60  and routine vaccinations (flu, pneumonia) have had similar findings.

The vaccinations that were looked at in this study were: the shingles (herpes zoster) vaccine, pneumococcal vaccine, and tetanus-diphtheria vaccine. Each of the vaccines lowered the risk of getting AD - the tetanus-diphtheria (Tdap/Td) by 30%, the shingles vaccine by 25%, and the pneumococcal vaccine by 27%. The adults were at least 65 years of age at the start of the study.

Why would vaccines be protective? There  are multiple theories, including that infection may play a role in the development of Alzheimer's disease (AD), and vaccines reduce the risk for infections. Or that vaccines may activate the immune system in such a way that alters the risk for developing AD.

Bottom line: In persons over the age of 60, getting routine adult vaccinations (including the flu vaccine) may lower the risk of developing AD. So simple!

From Medical Xpress: Several vaccines associated with reduced risk of Alzheimer's disease in adults 65 and older

Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research from UTHealth Houston. ...continue reading "Routine Vaccines Associated With A Reduced Risk of Developing Alzheimer’s Disease"

Published on Leave a comment on Breast Milk Contains Important Micronutrient For Brain Development
Breastfeeding
Credit: Wikimedia Commons/ Anton Nosik

Another new micronutrient has been discovered in breast milk. This is a sugar molecule called myo-inositol that promotes brain development in infants.

Researchers found that this sugar molecule is most abundant in human breastmilk early after birth when neuronal connections are rapidly forming in the infant brain. Three weeks after birth the levels found in breast milk slowly start to decrease.

This micronutrient was found in breast milk from women at all three study sites (Mexico City, Shanghai, and Cincinnati) - and at similar levels. The researchers stated that this could be one of the reasons why breast milk is so beneficial for a baby's brain development.

Interestingly, adults get myo-inositol from foods, with an adult eating a Western diet getting about 1 gram per day. It is also produced in the brain and other organs. It is especially abundant in fruits (e.g., cantaloupe and oranges), beans, grains, and nuts.

From Medical Xpress: Sugar molecule found in breast milk boosts infant brain development

Breast milk is not simply sustenance. It also is rich in micronutrients that are critical for healthy brain development in infants. ...continue reading "Breast Milk Contains Important Micronutrient For Brain Development"

Published on Leave a comment on CTE Found In Female Professional Athlete

No one should be surprised that chronic traumatic encephalopathy (CTE) has now been diagnosed (after death) in a female professional athlete - Heather Anderson. Years of repeated head trauma, whether from concussions or subconcussive hits, can eventually cause CTE. Head trauma, whether in males or females, occurs from body hits in football, rugby, heading the ball in soccer, and checking in ice hockey.

Heather Anderson was an Australian rules football player who started playing when she was 5, also played rugby, and eventually competed in the top women's Australian rules football league, retired at 23 after a shoulder injury, and committed suicide at 28. Both Australian rules football and rugby are contact sports. After death, her brain was examined and found to have the lesions characteristic of CTE.

CTE symptoms include memory loss, impaired judgement, confusion, aggression, depression, thinking about suicide, and eventually dementia. There is progressive degeneration of brain tissue in CTE, as well as build-up of the abnormal protein tau in the brain.

From NY Times: C.T.E. Found for First Time in Female Pro Athlete

For the first time, the degenerative brain disease chronic traumatic encephalopathy, or C.T.E., has been diagnosed in a female professional athlete, researchers reported. ...continue reading "CTE Found In Female Professional Athlete"

Published on Leave a comment on Carbon Dioxide Levels Are Higher Than Ever In the Atmosphere

Holy moly! Our carbon dioxide levels are rising, really rising! Every year there is a new high, and this year is no exception.

According to NASA, in May at the Mauna Observatory in Hawaii the carbon dioxide measurement was 421 ppm. It's called the "global atmospheric carbon dioxide concentration". This week the reading at Mauna Launa Observatory is 423.96 ppm. It's going up! And yup, this is climate change.

From the NASA Global Climate Change page on Carbon Dioxide (go to the link to see the graphs, and prepare to be shocked).

Carbon Dioxide  LATEST MEASUREMENT:  May 2023     421 ppm

Key Takeaway: Carbon dioxide in the atmosphere warms the planet, causing climate change. Human activities have raised the atmosphere’s carbon dioxide content by 50% in less than 200 years.

Carbon dioxide (CO2) is an important heat-trapping gas, or greenhouse gas, that comes from the extraction and burning of fossil fuels (such as coal, oil, and natural gas), from wildfires, and from natural processes like volcanic eruptions.

Since the beginning of industrial times (in the 18th century), human activities have raised atmospheric CO2 by 50% – meaning the amount of CO2 is now 150% of its value in 1750. This is greater than what naturally happened at the end of the last ice age 20,000 years ago.

The animated map shows how global carbon dioxide has changed over time. Note how the map changes colors as the amount of CO2 rises from 365 parts per million (ppm) in 2002 to over 400 ppm currently. (“Parts per million” refers to the number of carbon dioxide molecules per million molecules of dry air.) These measurements are from the mid-troposphere, the layer of Earth's atmosphere that is 8 to 12 kilometers (about 5 to 7 miles) above the ground.

One big concern that needs to be addressed: What will high carbon dioxide levels do to our thinking processes? Over the years carbon dioxide levels have been rising, and are now at levels not experienced in several million years!

Think of a "stuffy room" where it is harder to think - this can already occur starting at about 600 ppm of CO2, and known to occur at 945 ppm and higher (in rooms with many people in them). While current CO2 levels are below that, we are faced with the possibility that if they keep rising we will get there eventually - and there will be no escape from the "stuffy room" feeling!

...continue reading "Carbon Dioxide Levels Are Higher Than Ever In the Atmosphere"

Published on Leave a comment on Eating A Diet Rich in Flavanols May Help With Memory

One fear people have is of developing problems with their memory in their later years, called age-related memory loss. A recent study finding a possible way to maintain memory in older adults is intriguing and offers hope. And best of all, it's fairly easy to do - just increase the intake of flavanol rich foods.

A large Columbia University study of adults over age 60 found that daily flavanol supplementation (cocoa extract with 500 mg flavanols) over a 3 year period improved the memory of persons whose diet was low in flavanol intake from foods, but not in persons with high intake of flavanols. The researchers suggest that a low flavanol diet is one of the drivers of age-related memory loss.

The researchers stated that flavanols only improved memory processes governed by the hippocampus, and did not improve memory mediated by other areas of the brain.

Flavanols are natural substances found in certain fruits and vegetables, especially berries, onions, kale, lettuce, tomatoes, apples, grapes, and cocoa. Flavanols are a type or class of flavonoids, all of which have health benefits. Eat a variety of plant foods (includes tea and wine) to ensure you're eating a variety of flavonoids.

Some other benefits of flavonoids: they are anti-inflammatory, anti-oxidative, have anti-mutagenic and anti-carcinogenic properties, lower heart disease death rates, and prevention of heart disease.

From Medical Xpress: Low-flavanol diet drives age-related memory loss, large study finds

A large-scale study led by researchers at Columbia and Brigham and Women's Hospital/Harvard is the first to establish that a diet low in flavanols—nutrients found in certain fruits and vegetables—drives age-related memory loss. ...continue reading "Eating A Diet Rich in Flavanols May Help With Memory"