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Category: breast cancer

Published on Leave a comment on Pesticides and Breast Cancer
Normal (left) vs cancerous breast (right), mammography image
Credit: National Cancer Institute

Many studies link pesticide exposure to the development of various cancers, including breast cancer. We tend to think of pesticide exposure as occurring when there is direct contact with the pesticide - for example during application, or when walking on lawns or areas with freshly applied pesticides. Yet... there are other routes that have been neglected in studies, such as washing pesticide contaminated clothes. 

At a recent webinar (42nd National Forum Series - The Pesticide Threat to Environmental Health), Carolina Panis, PhD, (Ass. Professor of Medicine at Western Paraná State University in Brazil, and Visiting Researcher at Harvard University and the University of Arizona) spoke about pesticide exposure in women and breast cancer.  She discussed her recent research showing that women occupationally exposed to pesticides (e.g., as farm workers) and diagnosed with breast cancer seem to have more aggressive disease, also at younger ages, than unexposed women. An increased mortality rate went along with this.

She also discussed an interesting finding regarding women living in farm areas (with heavy pesticide use) in Brazil. Not only is occupational exposure to pesticides linked to breast cancer, but additionally - women having chronic (daily) exposure are also exposed to pesticide residues when washing clothing used by someone who had applied pesticides. Laundry exposure! Women absorb pesticide residues (e.g., glyphosate, atrazine) from the pesticide contaminated clothing, which increases the amount of pesticides in their bodies and this is also linked to breast cancer.

The women she looked at lived in farming areas, and additionally many had their residences frequently sprayed for insects. Ultimately, women exposed to high levels of pesticides tend to develop metastatic untreatable breast cancer, and at a younger age (unlike other areas where breast cancer is highly treatable). She pointed out that pesticides also have a negative effect on the immune system.

From the article by C. Pannis and B. Lemos: Pesticide Exposure and Increased Breast Cancer Risk In Women Population Studies

Women in rural regions are at risk for exposure to pesticides by equipment decontamination, unprotected clothes washing, pesticide drift, chemical spraying in the field, and other routes of exposure in the household. Pesticides can act on mammary gland cells in direct and indirect ways, augmenting the risk for breast cancer development. ...continue reading "Pesticides and Breast Cancer"

Published on Leave a comment on Another Reason to Avoid High-Fructose Corn Syrup
Soda Credit: Wikipedia

More worrisome news about high-fructose corn syrup. Researchers found that high fructose corn syrup actually speeds up and fuels the growth of cancer tumors in animals who already have cancer.

While this study was done in mice (with either breast cancer, melanoma, or cervical cancer), it is actually a scary finding because so many foods that Americans ingest daily contain high-fructose corn syrup. It is a sugar derived from corn starch and found in many foods: baked goods, soda, fast food, cereals, ice cream, etc. If you see it in an ingredient list, it means it is an ultra-processed food.

Bottom line: Read food ingredient lists and try to avoid eating foods with high-fructose corn syrup.

Excerpts from US Right To Know: High-fructose corn syrup fuels tumor growth in animals with cancer, a new study shows

High-fructose corn syrup, a sweetener commonly used in soda and ultra-processed foods, accelerates cancer tumor growth via the liver, according to research published last week [Dec. 4, 2024] in Nature.

High-fructose corn syrup (HFCS) is a sugar derived from corn starch. High fructose intake has been shown to contribute to the development of non-alcoholic fatty liver disease (NAFLD) and obesity, both of which are associated with systemic inflammation and altered lipid metabolism (the way the body processes fats). It has also been linked to diabetes, heart disease, and colorectal cancer. ...continue reading "Another Reason to Avoid High-Fructose Corn Syrup"

Published on Leave a comment on Can Mammograms Increase Risk of Breast Cancer?
Mammography image Credit: National Cancer Institute

Women have been advised by their doctors to get frequent mammograms for decades. However, what if frequent (e.g., annual) mammograms result in an increased risk for breast cancer due to exposure to X-rays? After all, there is a cumulative dose from the mammograms - year after year you get exposed to a little ionizing radiation, but it builds up over time.

Dr. Seth Hardy (radiologist and Associate Professor at Penn State Univ.) discusses this issue, while referencing research by Dr. Daniel Corcos about the possibility of some breast cancers occurring from the cumulative radiation from previous mammograms. This is because radiation is a carcinogen (can cause cancer).  [NOTE: studies find that over the years breast cancer treatments have so improved that any benefits of mammography screening are diminished.]

From Dr. Seth Hardy, writing at Sensible Medicine: The Ethics of Screening Mammography

The value of breast cancer screening with mammography is increasingly being questioned. Women are trying to decide what is right for them and the USPSTF is trying to decide what is worthy of reimbursement. Currently, the medical literature is at a stalemate.[1]1 ...

Screening mammography uses ionizing radiation, a known carcinogen. The dose of radiation in each exam is very low, but exposure is cumulative. Also, the absorbed dose varies with the density of the breast. Women with more glandular tissue receive a higher exposure. Thus, over decades of screening, radiation exposure may not be trivial, particularly in women with extremely dense breasts. 

Across a population there is some percentage of breast cancers which are caused by screening mammography. The exact number is the subject of debate and not well studied. One article from 2011 approximates 86 cancers and 11 deaths per 100,000 women due to breast cancer screening. Another paper estimates 20-25 fatalities for 100,000 women screened starting at age 40. Due to lack of data, and ethical limitations in obtaining more data, we do not know how many breast cancers are caused by screening. ...continue reading "Can Mammograms Increase Risk of Breast Cancer?"

Published on Leave a comment on Food Additives and Higher Cancer Risk

Most Americans eat highly processed or ultra-processed foods every single day, with most of their daily calories from them! There are all sorts of health risks from these foods, with a recent study finding an overall increased risk of cancer, as well as prostate and breast cancer.

Emulsifiers are food additives found in many ultra-processed foods. A large French study found that higher intakes of the emulsifiers carrageenan, mono and diglycerides are linked to an overall increased risk of cancer, as well as an increased risk in prostate and breast cancers.

Bottom line: Read the ingredients listed on labels! As much as possible, try to only buy and cook foods with ingredients that you would find in a kitchen. For example, flour, sugar - yes, chemical sounding names - no.

From Medscape: Are Food Emulsifiers Associated With Increased Cancer Risk?

...continue reading "Food Additives and Higher Cancer Risk"

Published on Leave a comment on Hundreds Of Common Chemicals Are Linked to Breast Cancer Risk

People worry about breast cancer and whether exposure to chemicals "in the environment" can lead to breast cancer. According to many studies the answer is: YES, absolutely - and this is why they are called carcinogens (a substance capable of causing cancer). What are the chemicals?

A recent study found that 921 chemicals are likely "breast carcinogens" and thus increase the risk of breast cancer. Many of these are commonly used in everyday products, including personal care products. The authors also pointed out that this list of chemicals is incomplete because information is not publicly available on many additional chemicals . (Unfortunately, the EPA is not asking for more information and testing to be done on many chemicals.)

The authors of the study point out  that breast cancer is "both the most commonly diagnosed cancer type and leading cause of cancer death among women worldwide". So knowing which chemicals could potentially cause breast cancer is important. Some examples: phthalates, parabens, many pesticides, endocrine disruptors.

Bottom line: Read ingredient lists in order to avoid many problematic chemicals. For example; if you see parabens or phthalates listed (e.g., in lotion) - avoid those products. Avoid fragrances, stain repellents, antimicrobials. Eat as many organic foods as possible (to avoid pesticide residues in non-organic foods). [See more tips on avoiding toxic chemicals.]

Also, avoid using pesticides as much as possible, and instead use least toxic Integrated Pest Management (IPM) or organic methods, both inside the home and outside.

Excerpts from Environmental Health News: More than 900 common chemicals linked to breast cancer risk: Study

More than 900 chemicals commonly found in consumer products and the environment have been linked to breast cancer risk in a new study. ...continue reading "Hundreds Of Common Chemicals Are Linked to Breast Cancer Risk"

Published on Leave a comment on Some Cancers In Women Linked to Chemical Exposures

Do you know what chemicals you're exposed to on a daily basis? A recent study found that women with cancers of the breast, uterus, skin (melanoma), or ovaries had significantly higher levels of certain endocrine disrupting chemicals in their bodies than women without any of those cancers.

The researchers looked at levels of some hormone disrupting chemicals: PFAS (per- and polyfluoroalkyl substances), phenols (e.g. BPA), and parabens in both men and women. They found that women had higher levels of endocrine disruptors for 4 types of cancers (breast, uterine, ovarian, and melanoma). However, there was no relationship between the endocrine disruptors and thyroid cancer in men or women, and no relationship in men with prostate cancer.

The reason the researchers looked at breast, prostate, thyroid, ovarian, endometrial, and testicular cancers, and melanoma is because they are "hormone-mediated" cancers. That is, hormones play a role in growth and progression of these cancers.

Bottom line: You cannot totally avoid these chemicals because they are used in so many products, but you can really lower your exposure to them. Read Avoiding Harmful Chemicals for easy tips on reducing your exposure to these harmful chemicals. For example, don't use non-stick pots and pans, don't use plug-in air fresheners, and try to use fragrance-free or unscented products as much as possible. Use paraben and phthalate-free personal care products.

From Medical Xpress: Study finds significant chemical exposures in women with cancer

In a sign that exposure to certain endocrine-disrupting chemicals may be playing a role in cancers of the breast, ovary, skin and uterus, researchers have found that people who developed those cancers have significantly higher levels of these chemicals in their bodies. ...continue reading "Some Cancers In Women Linked to Chemical Exposures"

Published on Leave a comment on Personal Care Products and Breast Cancer Risk

For years there has been much concern over chemicals that act as endocrine disruptors (hormone disruptors) in the personal products that we use on a daily basis.  One big concern is whether these chemicals, such as parabens and phthalates, are causing breast cancer (as well as other harmful health effects). Because whatever you use on your skin, will get into you.

A recent study looking at these harmful chemicals found that women switching to paraben and phthalate free cosmetic products had a quick effect (within 28 days) on lowering their levels in the body (blood, urine, breast tissue cells). Which then resulted in lowering breast cancer markers to a "normal" expression. Wowza!

What you can do: Check the ingredients in the lotions you use. Are there parabens and phthalates in it? Spend your money on safe lotions and other personal products. Go to EWG (ewg.org) or mamavation.com for lists of safe products. Also: Ways to lower your exposure to harmful chemicals

For example, the commonly used lotion Lubriderm to this day has several types of parabens (e.g., methylparaben) in it. No, no, no... Why are they still in the lotion? Note that our government is not protecting us from these harmful chemicals. (Instead Big Business and big money is more important.)

From Environmental Health News: Get phthalates, parabens out of the bathroom drawer to reduce breast cancer risk: Study

Switching to phthalate and paraben-free personal care products could reduce the risk of developing breast cancer, according to new research. ...continue reading "Personal Care Products and Breast Cancer Risk"

Published on Leave a comment on The EPA Is Still Approving Pesticides Linked To Breast Cancer

The EPA has many serious problems, from protecting corporations and not consumers, to ignoring studies that find health problems with products or chemicals. Dr. Jennifer Liss Ohayon, a research scientist at Silent Spring Institute and Northeastern University, pointed out in a recent article that the EPA keeps approving pesticides linked to breast cancer.

These pesticides act as endocrine disruptors on the breast, with effects occurring at low doses. Many are commonly used (e.g., malathion, atrazine), which means women are exposed to in food, water, the workplace, and at home (yes - home, garden, and lawn chemicals!).

Why be concerned? Young women are experiencing earlier breast development, difficulty in breastfeeding, and increasing rates of breast cancer. Many studies link this in women (and in animals) with chemical exposures, especially endocrine disrupting chemicals (this is because they screw with hormones, and so have an effect on breast development and breast tissue).

But... the EPA is dismissing or ignoring relevant studies and pooh poohing the idea that chemicals can have harmful endocrine disrupting effects. Effects on the breast (mammary gland) are NOT required to be part of the EPA's chemical risk assessment (which determines whether a pesticide will be approved). The studies the EPA relies on are almost all financed by the manufacturers (hmmm...of course they'll say the pesticide is safe).

Note that the European Union bans many of the worrisome pesticides - they are not ignoring the science, and in doing so protect people.

From a piece by Dr Jennifer Liss Ohayon at Environmental Health News (EHN): Why is the EPA still exposing women to pesticides linked to breast cancer?

This fall marks the 60th anniversary of writer and scientist Rachel Carson’s 1962 book “Silent Spring.” The book was seminal in that it sparked the modern environmental movement, a U.S. ban of DDT, and the founding of the Environmental Protection Agency (EPA). However, despite decades passing since Carson first warned us about the dangers of pesticides, EPA continues to approve pesticides linked to breast cancer. ...continue reading "The EPA Is Still Approving Pesticides Linked To Breast Cancer"

Published on Leave a comment on A Dietary Supplement That Might Increase Cancer Risk

Some dietary supplements can do serious harm, especially when taken in high doses. A recent study found cancer associated with high doses of the supplement nicotinamide riboside (NR), which is a form of vitamin B3.

Keep in mind that this study was done in vivo and in vitro (in a lab), and also in mice.. and not humans. But the results are concerning.

Swiss and Univ. of Missouri researchers found that high levels of NT could increase the risk of developing triple-negative breast cancer, and also for it to metastasize to the brain. Yikes.

By the way, while NR can be purchased as a supplement, it is normally not found in ordinary multi-vitamins that many take daily. Low levels of NR are found in fruit, vegetables, meat, and milk - it is necessary for health (it increases levels of cellular energy). It's the large amounts found in supplements that the researchers were concerned with and that can be problematic.

Stay tuned for further research...

From Science Daily: Popular dietary supplement increases breast cancer risk, brain metastasis, study suggests

While previous studies have linked commercial dietary supplements like nicotinamide riboside (NR), a form of vitamin B3, to benefits related to cardiovascular, metabolic and neurological health, new research from the University of Missouri has found NR could actually increase the risk of serious disease, such as development of breast cancer and brain metastasis. ...continue reading "A Dietary Supplement That Might Increase Cancer Risk"

Published on Leave a comment on Breast Cancer Vaccine Now Being Tested
Normal (left) vs cancerous breast (right), mammography image
Credit: National Cancer Institute

This is very preliminary, but everyone is excited over a breast cancer vaccine now being tested. The vaccine is meant to treat women who have breast cancer.

University of Washington researchers tested the vaccine for safety (it was very safe) and to see what was a good dose for women in a Phase 1 Clinical Trial. But the 66 women it was tested on (all who had metastatic breast cancer that had been treated) overall did much better than expected. Fabulous!

The next trial will soon start (Phase 2) with women at different stages of breast cancer. Stay tuned!

From Medical Xpress: Breast cancer vaccine safely generates anti-tumor immunity

An experimental vaccine against breast cancer safely generated a strong immune response to a key tumor protein, researchers from the University of Washington School of Medicine in Seattle report in a paper published by the journal JAMA Oncology. The findings suggest the vaccine may be able to treat different types of breast cancer.

"Because this was not a randomized clinical trial, the results should be considered preliminary, but the findings are promising enough that the vaccine will now be evaluated in a larger, randomized clinical trial," said lead author Dr. Mary "Nora" L. Disis, a UW professor of medicine, Division of Medical Oncology, and director of the Cancer Vaccine Institute. ...continue reading "Breast Cancer Vaccine Now Being Tested"