
Did you know that a significant percentage of men lose the male sex chromosome in some of their cells as they age? About 40% of 70 year olds! This loss may explain why so many men die several years before women.
The loss of the male Y chromosome in some cells (mosaic loss) has health effects. It is associated with an increased risk of early death and some age-related diseases in men, such as heart disease and heart failure. This loss mainly happens in cells with a rapid turnover, such as blood cells, and does not happen in male reproductive cells.
A recent two part study in both mice and human males found that this Y chromosome loss resulted in heart muscle scarring (fibrosis), which led to increased risk of heart problems and heart failure. The researchers discuss a drug (pirfenidone) that may help with treatment.
Why is this happening? The researchers point out that as we age, more and more gene mutations are occurring, that is, the DNA of our cells accumulate mutations as we age. Some of them are due to our own choices, such as smoking, exposures to toxic chemicals, radiation, our lifestyle. Others are out of our control (e.g., aging).
From Science Daily: Loss of male sex chromosome leads to earlier death for men
The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows. The finding may help explain why men die, on average, several years younger than women. ...continue reading "Many Men Lose the Male Sex Chromosome As They Age"
Americans spend enormous amounts of money on vitamins and mineral supplements in an effort to stay healthy or to improve their health. Unfortunately, unless a person has an actual vitamin or mineral deficiency, studies are just not finding health benefits. Sometimes there are even harms.
What to do to maintain or improve health? Eat a healthy diet rich in fruits, vegetables, whole grains, legumes (beans), seeds, and nuts. Get enough exercise or physical activity. Don't smoke. Maintain a healthy weight.
Eating berries frequently or daily has all sorts of health benefits. Two recent studies have focused on daily consumption of cranberries and found them to be beneficial for memory and neural functioning, and also for heart health.
From Medscape:
The studies are coming fast and furious about how all daily physical activity has health benefits. Ordinary daily activities that cause a person to move, such as housework, vacuuming, washing dishes, gardening, walking, cooking, even showering - all count. (On the other hand, reading and computer use do not.)
Many people think that only exercises done in a gym, in exercise classes, or with exercise equipment can improve health. But no! Any physical activity is good, which means ordinary walks and household tasks or housework are beneficial. And the more frequently you do them, the more beneficial.
Once again research finds health benefits from consumption of olive oil. A recent
Atrial fibrillation (a quivering or irregular heartbeat) can be very frightening for the person experiencing it. This heart arrhythmia disorder can be treated with medicines or surgical ablation, but new research suggests that it also can be improved after 6 months of exercise - about 3.5 hours per week.
Recently there have been studies with conflicting results about the health benefits or harms from coffee consumption. Overall, it seems like moderate intake is OK and beneficial for adults, but too much may cause harm. And avoid
The results of a