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Credit: Wikipedia

Well, well, well...It's unbelievable, but we've reached a point in this country where vaccines and their effectiveness have to be defended. To combat disinformation and misinformation, doctors have set up a database of vaccines and all the studies that have studied them - whether they work, how well they work, how they were done, and any adverse effects.

Dr Jake Scott, an infectious disease specialist at Stanford University, and his colleagues created a spreadsheet documenting randomized controlled trials (the best kind or research!) conducted for licensed vaccines. There are over 300 such trials listed in the spreadsheet, some of them conducted as early as the 1950s (e.g., the massive polio Salk Vaccine Field Trial). And the vast majority include the safety data (whether the vaccine is safe).

Dr. Scott points out that the evidence (all those studies!) shows that people claiming that vaccines (including childhood vaccines) have not been tested in randomized trials are "unequivocally, demonstrably, measurably false". Vaccines have been studied over and over. And they work!

Information about the spreadsheet and the randomized controlled studies (RCTs) for each vaccine are discussed in an interview with Dr. Jake Scott. Excerpts from CIDRAP (Center for Infectious Disease Research and Policy): Vaccine RCT spreadsheet aims to show the data, dispel myths about vaccines

Since late April, an infectious diseases specialist at Stanford University and his colleagues have been volunteering their time on a project they hope will help educate the public, and combat misinformation, about the safety and efficacy vaccines.

The project, led by Jake Scott, MD, is a spreadsheet of all the randomized controlled trials (RCTs) that have ever been conducted for licensed vaccines. The idea, hatched on the social media site X, was prompted by responses to an old video of current Department of Health and Human Services Secretary Robert F. Kennedy Jr., in which he claims that none of vaccines mandated for US children has ever been tested in preclinical studies against a placebo. In one of the responses, infectious disease physician Brad Spellberg, MD, suggested a crowd-sourced effort to identify and post all of the RCTs in which vaccines have been tested against a placebo. ...continue reading "New Database of Vaccine Studies, Their Safety, and Their Effectiveness"

Nanoparticle form of titanium dioxide Credit: Wikiedia

Titanium dioxide has been a problematic food additive for years. The European Union banned the additive several years ago, while the FDA views titanium dioxide as safe. Recently, the company (Mars) that makes the candy Skittles announced that it was removing the additive from the ingredients.

Well, it took a lawsuit filed in 2022 alleging that Skittles are "unfit for human consumption" (because of the ingredient titanium dioxide) to finally have the manufacturer remove it from the product. Removing titanium dioxide  won't change the taste - it's only used as a "brightener" (makes colors brighter).

In the past decade, a number of studies found that the nanoparticle ((between 1 and 100 nanometers) form of titanium dioxide to have harmful health effects, especially to the gut (intestines) [see post]. This is the form typically used in over 11,000 products in the US, all ultra-processed (many candies, baked goods, gum, frosting, snack foods, etc.)

Bottom line: Read food ingredient lists, and avoid titanium dioxide (if possible).

From Medical Xpress: Skittles removes controversial additive targeted by RFK Jr.

Mars Inc.'s Skittles candies are no longer being made with titanium dioxide, a chemical that whitens foods, brightens colors and makes candy appear shiny, the company confirmed to Bloomberg News. ...continue reading "Titanium Dioxide Will No Longer Be Added To Skittles"

Titanium dioxide nanoparticles Credit: Wikipedia

Titanium dioxide appears in many foods and some medicines (e.g., Allegra), in order to make colors and whites look brighter. In other words, it is an unnecessary food additive, found in a large variety of (ultra-processed) foods, including some candies, gum, frosting, soups, and even macaroni and cheese. It is allowed in the US (in over 11,000 food products!), but banned in Europe due to its harmful health effects.

A number of studies have linked titanium dioxide in its small nanoparticle form (between 1 and 100 nanometers) with a number of health harms, including to the gut (intestines). A recent study found that nanoparticle titanium dioxide has harmful or disruptive effects on the intestinal endocrine (hormone) system, resulting in abnormal blood sugar (glucose) levels, which can lead to insulin resistance and diabetes. It also caused intestinal lining changes, reduced levels of gut hormones, and resulted in a drop in enteroendocrine cells

Larger particles of titanium dioxide Credit: Wikipedia

While the study was done in mice, the results are also thought to apply to humans. The study didn't find the same health harms from larger titanium dioxide particles called microparticles (about the size of a fine grain of sand), but only from the nanoparticles. The problem is that nanoparticles are so small that once ingested, they get into cells and tissues throughout the body. However, large particles can be excreted from the body.

Bottom line: Unfortunately, it's the small nanoparticles that are so common in foods that we ingest. Read labels carefully and try to avoid those with titanium dioxide or artificial colors (includes titanium dioxide).

Excerpts from two informative articles: 1) From investigative journalism site US Right to Know: Tiny titanium dioxide particles in food raise blood sugar, disrupt gut hormones in mice, study finds

The study, published this month [May 2025] in Food and Chemical Toxicology, adds to growing concerns over the safety of titanium dioxide (TiO₂), a widely used color additive that is banned in the EU but widely used in the U.S. and elsewhere. It also highlights the food industry’s increasing use of microscopic materials to preserve or enhance foods.  ...continue reading "Health Effects From Titanium Dioxide In Foods"

Once again artificial sweeteners are in the news, and not in a good way. New research found that the sugar substitute erythritol, at a concentration typically found in an artificially sweetened beverage, has harmful effects on the small blood vessels of the brain.

Erythritol crosses the blood brain barrier and interacts with the brain's cerebrovasculature (the blood vessels in the brain, including the arteries, veins, and capillaries that supply blood and nutrients to the brain tissue). This study focused on the smallest blood vessels (microvascular) in the brain. And yes, found that the amount or erythritol in 1 diet beverage has adverse effects at a cellular level on these blood vessels.

This study was done in a lab setting (and not directly on humans), but research results match up with other studies on erythritol. Other studies already found that erythritol increases the risk of heart attacks, heart disease, strokes, as well as blood clot formation. This study's results give an explanation for why there is a increased risk of these brain vascular (blood vessel) events happening.

Erythritol is found in some beverages advertised as low or zero calorie (e.g., Monster Zero energy drinks, Blue Sky Zero Sugar soda, Red Bull Zero) and in some low calorie foods (e.g., Halo Top low-calorie ice cream). Read ingredient lists on labels!

From Medical Xpress: Major sugar substitute found to impair brain blood vessel cell function, posing potential stroke risk

Erythritol may impair cellular functions essential to maintaining brain blood vessel health, according to researchers at the University of Colorado Boulder. Findings suggest that erythritol increases oxidative stress, disrupts nitric oxide signaling, raises vasoconstrictive peptide production, and diminishes clot-dissolving capacity in human brain microvascular endothelial cells. ...continue reading "The Sugar Substitute Erythritol And the Brain’s Blood Vessels"

Over the past decade there has been as increasing amount of research suggesting that the herpes virus (cold sores!) is implicated in the development of Alzheimer's disease. (here, here, here).

A recent study suggests the same possibility - herpes simplex 1 (HSV-1) has a role in the development of Alzheimer's disease. And treating cold sores with antiviral therapy (antiherpetic medications) results in a reduced risk of developing Alzheimer's disease - thus the antivirals are protective.

The researchers found that having herpes virus type 2 (genital herpes) and varicella zoster virus (chicken pox, shingles) also resulted in increased risk of later developing Alzheimer's disease. But infection with cytomegalovirus was not.

From Medical Xpress: Cold sore viral infection implicated in development of  Alzheimer's disease

Symptomatic infection with the virus responsible for cold sores around the mouth–herpes simplex 1, or HSV-1 for short—may have a key role in the development of Alzheimer's disease, suggests a large US study published in BMJ Open. ...continue reading "Herpes Simplex Virus and Alzheimer’s Disease"

Studies find that exercise or physical activity improves the functioning of the brain, including memory and overall cognition. In a recent study, almost two weeks of exercise by older adults improved brain insulin signaling - that is, it improved the abilities of insulin to act on the brain by increasing "neuronal extracellular vesicles".

The study found these beneficial effects on a group of sedentary adults (average age 60) with prediabetes, who are at higher risk for Alzheimer's disease and dementia.

The participants exercised twelve times (60 minutes per day) by using a stationary bicycle (cycle ergometry exercise) over a 13 day period. So quick and simple, but it resulted in health benefits for the brain.

From Science Daily: Exercise improves brain function, possibly reducing dementia risk

A study led by scientists at Rutgers University-New Brunswick has shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function. ...continue reading "Exercise, Insulin, and the Brain"

Exercise boosts brain function at all ages. This means that for both young and old, it is worth it to get out and engage in physical activity.

A large study reviewed other studies (for a total of 258,279 persons) on effects of exercise on brain functioning. They found that exercise, even light exercise, boosts brain function (specifically general cognition and executive function) and memory. Executive function refers to mental processes (executive functioning skills) that help you solve problems, make plans, set and carry out goals, and manage emotions.

The researchers concluded that most forms of exercise appear effective, including light-intensity activities, and even yoga, Tai Chi, and walking. The positive effects were found at all ages, and in all groups studied. There seemed to be an especially strong effect in persons with ADHD

From Science Daily: Exercise of any kind boosts brainpower at any age

Whether it's an early morning jog, or a touch of Tai Chi, groundbreaking research from the University of South Australia shows that any form of exercise can significantly boost brain function and memory across children, adults, and older adults. ...continue reading "Exercise Boosts Brain Function At All Ages"

Many people (even health professionals) are still under the impression that dairy products made from milk are unhealthy. NOT TRUE. Consuming dairy products, especially whole milk products, is associated with a number of health benefits.

Recent research adds to the growing body of research finding that higher intake of dairy products is associated with a lower risk of colorectal cancer (commonly referred to as colon cancer). One big review found a 20% decrease in colon cancer with higher dairy product consumption, and an 18% decrease in colon cancer specifically with higher milk consumption.

The researchers discussed studies that found that with each 400 g (about 1 3/4 cups) of dairy foods that people consumed daily, there was a 13% reduced risk of colorectal cancer.

It's more than the calcium found in the dairy products (there is research already finding that calcium in foods is associated with lower risk of colorectal cancer). And it's more than dairy products that are fermented (e.g., yogurts). It's high fat milk products (whole milk) that have the highest association. But currently it's unclear why.

Excerpts from Medscape: Does Higher Dairy Intake Reduce CRC Risk?

Two recent studies have added to the growing body of research suggesting consuming more dairy reduces a person’s risk of getting colorectal cancer. ...continue reading "Dairy Products and A Lower Risk of Colorectal Cancer"

Tooth Credit: Wikipedia

We are all encouraged to brush our teeth daily with a toothpaste containing fluoride. We assume that the toothpaste is safe and free from dangerous chemicals and heavy metals, such as lead, but it turns out that our assumptions are wrong.

A consumer group had independent lab analyses done of 51 toothpaste brands. They found toxic heavy metals in most toothpaste brands, even those marketed as green and pure. The presence of heavy metals such as lead was detected in 90%, arsenic in 65%, mercury in 47%, and cadmium in 35% of the toothpaste brands.

However, none of the brands tested had levels exceeding current FDA guidelines: the lead limit for fluoride free toothpaste is 10,000 ppb and 20,000 ppb for fluoride toothpastes. But Washington state recently enacted much lower lead level limits of 1000 ppb (and some brands exceeded those levels).

The toothpaste brands containing heavy metals (at varying levels) included Crest, Sensodyne, Tom's of Maine, Dr Bronner;s, Davids, and others. [Note: Arm and Hammer was not tested]. It is thought that the heavy metals (especially lead) was from ingredients added to many toothpaste brands: hydroxyapatite, calcium carbonate and bentonite clay.

The work was funded by The Lead Safe Mama, LLC (LSM) team. This group has been conducting independent, community-funded, scientific testing of consumer goods since 2009. Since March 2024 they have been conducting independent laboratory testing of foods, supplement, cosmetics, and personal care items.

From The Guardian: Toothpaste widely contaminated with lead and other metals, US research finds

Toothpaste can be widely contaminated with lead and other dangerous heavy metals, new research shows. ...continue reading "Lead and Heavy Metal Contamination In Toothpaste"

Typically, our vitamin D levels drop in the winter months when we don't get as much sun exposure. After all, it is called the sunshine vitamin. However, a new study found that regular moderate-intensity exercise kept vitamin D levels up in the winter, even without vitamin D supplements or weight loss.

Good reason to exercise - prevent the usual seasonal decline in vitamin D. How much exercise? In the study, overweight adults had four indoor cardiovascular exercise sessions per week for 10 weeks: two treadmill walks, one longer steady-state bike ride, and one high-intensity interval bike session

From Science Daily: Exercise the key to maintaining Vitamin D levels in winter

The sun may be shining now, and our vitamin D levels are getting a natural boost but it wasn't long ago we were in the depths of winter, when sunlight was scarce and vitamin D was in short supply. ...continue reading "Regular Exercise In Winter Months Keeps Vitamin D Levels Up"