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Soda Credit: Wikipedia

All of us should be concerned about harmful health effects from a sedentary lifestyle, along with drinking lots of sugary soda. However, according to a (very) small study, ten days of adopting this lifestyle seems to have more of a negative effect on healthy young men than on women, at least in the short term.

Even just 10 days of reducing physical activity (from greater than 10,000 steps to less than 5000 steps per day) and increasing soda intake (to 6 cans a day!) was enough to have a negative effect on insulin levels (vascular insulin resistance) in healthy young men. But the Univ. of Missouri researchers found no real effect on the young women.

From Medical Xpress: Sedentary lifestyle and sugary diet more detrimental to men, study finds

A new study from the University of Missouri School of Medicine is the first evidence in humans that short-term lifestyle changes can disrupt the response to insulin of blood vessels. It's also the first study to show men and women react differently to these changes. ...continue reading "Ten Days of Unhealthy Lifestyle Has Greater Effect on Young Men than Women"

One of the fears about aging is the possibility of developing dementia. Even in healthy older adults it is normal for the brain to slowly shrink with increasing age, and thinking processes can deteriorate. A recent study lasting 78 weeks offers hope to persons already diagnosed with mild cognitive impairment (MCI).

In older adults with MCI, there is an increased risk it can progress to dementia, especially Alzheimer's disease. Studies are finding that doing complex mental activities that stimulate the brain may decrease the risk of cognitive decline and dementia.

In this study, researchers found that doing crossword puzzles was better than doing computer games in improving memory loss and thinking processes, and slowing the progression of decline in persons already diagnosed with MCI. The crossword puzzle group also showed less decline in daily activities, and MRIs showed fewer decreases in brain size (hippocampal volume and cortical thickness).

Persons (average age 71.2 years) were randomized to either of the groups, and they did the online games or crossword puzzles (provided by Lumos Labs) at home. Total time spent each day: 30 minutes four times per week.

Are online crossword puzzles better than computer games for persons without any cognitive impairment?  This is where it gets interesting - the answer is no. One study found that computer games were better in a group of 18 to 80 year olds, even though doing either results in improvement.

By the way, numerous "brain training" claims by a computer mind games company such as Lumos Labs were viewed as deceptive by the FTC ($2 million fine back in 2016 for all sorts of unsupported claims).

What to do for brain health? The reality is that activities that stimulate the mind (reading, art, computer games), getting vaccines in adulthood, and exercise/physical activity are all good for the brain. And of course, eating well (especially more fruits, berries, nuts, and eggs) and getting enough sleep. Avoid anticholinergic medicines and smoking.

Mild cognitive impairment (MCI) can even improve on its own without any special treatments - even in adults 65 years or older.

From Medical Xpress: Crossword puzzles beat computer video games in slowing memory loss

A new study by researchers from Columbia University and Duke University published in the journal NEJM Evidence shows that doing crossword puzzles has an advantage over computer video games for memory functioning in older adults with mild cognitive impairment. ...continue reading "Crossword Puzzles Are Good For the Brain"

Eating nuts is good for your health. A study conducted in the UK found that eating either a handful (56 grams) of whole or ground almonds every day for 4 weeks significantly increased the production of butyrate, a short-chain fatty acid that promotes gut health.

The study participants were persons eating a typical Western diet - low in fiber (less than the recommended amount), and with daily unhealthy snacks (chips, crisps, candy). The control group ate a muffin instead of almonds, and showed no improvements over the 4 weeks of the study. None of the 3 groups had significant changes at the microbiome level, which wasn't surprising because the rest of their diets stayed the same.

In other words, in a person who normally eats a typical Western diet - eating an additional handful of nuts daily helps with butyrate production (good!) and provides extra nutrients. But it's not enough of a dietary change to have a significant effect on the microbiome. For gut microbiome improvement need to add some fermented foods and more fruits, vegetables, whole grains, seeds, legumes, and nuts.

From Science Daily: Snacking on almonds boosts gut health, study finds

Eating a handful of almonds a day significantly increases the production of butyrate, a short-chain fatty acid that promotes gut health. ...continue reading "Almonds Are Good For You"

Many of us do not get enough sleep at night. Unfortunately, this is bad for our health. Another large study just confirmed this - they found that consistently getting 5 or fewer hours per night during mid-life or later in life is linked to developing several diseases.

Sleeping 9 or more hours at 60 or 70 years of age (but not at age 50) was also associated with developing multiple chronic diseases. No association was found between sleep duration and early death among those with existing chronic diseases.

The study, conducted in the UK, looked at sleep amounts in more than 7000 persons over a 25 year span (when they were 50, 60, and 70 year old). Persons with short sleep duration (5 or fewer hours) had a higher risk of developing not just one chronic disease, but multiple chronic diseases.

The possible chronic diseases were: diabetes, cancer, coronary heart disease, stroke, heart failure, chronic obstructive pulmonary disease (COPD), chronic kidney disease, chronic liver disease, depression, dementia, mental disorders, Parkinson's disease, arthritis/rheumatoid arthritis.

From Science Daily: Five hours' sleep a night linked to higher risk of multiple diseases

Getting less than five hours of sleep in mid-to-late life could be linked to an increased risk of developing at least two chronic diseases, finds a new study led by UCL researchers. ...continue reading "Sleeping Less Than Five Hours A Night Ups the Risk For Health Problems"

Pesticides causing health problems are appearing in study after study. A recent study found that higher glyphosate levels in pregnant women is associated with lower birthweight in the babies and higher risk of admission to neonatal intensive care units.

Studies find that almost all pregnant women have detectable levels of glyphosate in their bodies - which of course reaches the fetus. In this study by Univ. of Indiana researchers it was detected in 99% of the women during the first trimester! Higher levels resulted in reduced fetal growth. This is very concerning.

Glyphosate is found in the popular herbicide (weed-killer) Roundup. The use of glyphosate has increased substantially with genetically modified crops (e.g., Roundup resistant crops such as corn and soybeans) and with its preharvest use in conventionally raised crops (preharvest guide). It's found on many regular oats, wheat, soybeans, canola, lentils flax, etc.

This is why with each new study higher levels are found in people. It's in our food.

What else is glyphosate doing to us? It has been linked to a number of human health effects, such as cancer, endocrine (hormone) disruption, liver and kidney damage, preterm birth, and even having a negative effect on our gut microbiome - by killing off certain important species of gut microbes. There is much we still don't know about chronic exposure to low levels of the pesticide.

By the way, the United States FDA allows higher levels of glyphosate residues in food and humans than other countries, including European countries. Of course this is due to the pesticide industry lobbying the FDA real hard, political interference, and then think of all those cushy pesticide industry jobs government workers eventually get as a reward. (Yes, it's revolving door from the government to industry jobs...)

Organic farmers are not allowed to use glyphosate. So if you want to avoid the pesticide - eat as many organically grown foods as possible.

From Science Daily: High exposure to glyphosate in pregnancy could cause lower birth weights in babies

Indiana University School of Medicine researchers are learning more about the effects of herbicide exposure during pregnancy, finding glyphosate in 99 percent of the pregnant women they observed in the Midwest. In the study, published recently in Environmental Health, higher glyphosate levels were associated with lower birth weight and may also lead to higher neonatal intensive care unit admission risk. ...continue reading "Almost All Pregnant Women Have This Pesticide In Their Body"

People have been saying this for years, but now a big study confirmed it: women and girls are better than men and boys at verbal fluency and remembering words. The difference may be small, but it is consistently there over the lifetime.

In other words, women have better verbal abilities. By the way, girls generally start talking earlier and with more complex speech than boys.

From Medical Xpress: Are women really better at finding and remembering words than men? Large study settles score

Textbooks and popular science books claim with certainty that women are better at finding words and remembering words, but is this really a fact?

"Women are better. The female advantage is consistent across time and life span, but it is also relatively small," says Marco Hirnstein, professor at The University of Bergen, Norway. ...continue reading "Large Study Finds Women Have Better Verbal Abilities Throughout Life"

One distressing fact about the world around us is that bird numbers are plummeting. The U.S. State of the Birds 2022 report has come out discussing the top 70 bird species that are at the "tipping point" -  at risk of becoming endangered. Look at the list to see if any of the bird species are found near where you live.

According to the Cornell Univ. researchers, the 70 "tipping point" species listed have already declined by at least 50% (or more) and could lose another half of their population in the coming years.

There are numerous reasons why bird numbers are dropping so rapidly (e.g., loss of habitat, pesticides, pollution), but there are also some positive steps you can personally take to help bird species around you survive. Additionally, this will help the environment and your own health (e.g., less pesticide exposure is good for health). Three simple steps to take:

#1 - Stop using lawn and garden pesticides. They poison birds landing on lawns, poison the insects they eat, poison critically important insect species such as bees, and also screw up lawn and garden microbial communities.

#2 - Instead, look for natural and non-toxic ways to control unwanted plants and insects. Practice IPM (Integrated Pest Management) or organic lawn and garden care. View "weeds" as wildflowers and welcome diversity.

#3 - Plant flowers and plant species that are beneficial to pollinators and birds. Plant native species.

Cornell Lab recommendations of 7 simple actions to take.

From State of the Birds 2022: Bird Declines Are Reaching a Tipping Point

In 2019, a study of 529 bird species with adequate long-term data for analysis (Science, Rosenberg et al.) found that 303 species in North America were declining—more than half of the bird species studied.  ...continue reading "Bird Species In Decline Have Reached A Tipping Point"

We all know that microbes (fungi, viruses, bacteria) live throughout our bodies - this is the human microbiome or microbiota. What is really interesting is that cancer tumors also have microbiomes (tumor microbiome), and these microbial communities are different than that found in healthy people (without tumors).

For a while it has been known that tumors (e.g., breast cancers) have different bacterial species than healthy tissue - the microbiome is different. Several recent studies find that tumors can also contain fungi, and cancers with certain fungal species have worse outcomes than those without the fungi. The mycobiome is the community of fungi that live in or on humans.

Also, the combination of fungal species are different depending on what kind of cancer that a person has. A group of scientists have put together a list (mycobiome atlas) of the distinctive fungi that are found with 35 different cancer tumors. This is exciting because in the future cancers could potentially be found by the microbial (fungi and bacteria) DNA they shed in the blood.

However, no one knows really why the fungi are in the tumors. For example, are they aiding the cancer development? Or is the cancer allowing the fungi to grow? Are the fungi interacting with the immune system? Or??

Several recent articles discuss this exciting new research.

From NY Times: A New Approach to Spotting Tumors: Look for Their Microbes

Look up an image of a tumor on Google, and you’ll probably end up with a brightly colored cluster of cancer cells on a drab background of healthy tissue. But for Lian Narunsky Haziza, a cancer biologist at the Weizmann Institute of Science in Israel, the picture looks very different. A tumor may also contain millions of microbes, representing dozens of species.

Scientists have long known that our bodies are home to microbes, but have tended to treat tumors as if they were sterile. In recent years, however, researchers have laid that notion to rest, demonstrating that tumors are rife with microbes. ...continue reading "Studies Find Fungi In Cancer Tumors"

Male sperm Credit: Wikipedia

Currently there is incredible concern over what the group of toxic chemicals called PFAS (per- and polyfluoroalkyl substances) are doing to humans. PFAS are commonly known as "forever chemicals" because of their persistence in our bodies and environment. They are all around us (e.g., in personal care products, cosmetics, food packaging, nonstick cookware, textiles, carpets), and as a consequence almost all of us have them in our bodies.

Why be concerned over PFAS chemicals? They are endocrine (hormone) disruptors and have numerous harmful health effects, including all sorts of reproductive effects (e.g., decreases in sperm numbers, increased rates of infertility), decreases in testosterone, increased risk of cancer, and immune effects. Studies also find that they cross the placenta and accumulate in the fetus.

Now another worrisome large study (864 young men, 18.9 to 21.2 years old) has been published. Danish researchers found that those men who had been exposed to higher levels of PFAS during pregnancy had lower levels of sperm (both sperm concentration and sperm count), and a higher proportion of not swimming correctly and nonmoving sperm in the adult sons. This means that prenatal exposure has an effect on both quantity and quality of sperm in adulthood.

The PFAS levels were first measured during pregnancy (in the mother's plasma) during the first trimester, when the male reproductive system is developing. Sperm counts have been dropping rapidly in the past 40 years throughout the developed world, and these chemicals may be one of the reasons.

Bottom line: We can't totally avoid these chemicals, but the good news is that we can lower by a lot how much we are exposed to. And your levels can go down within weeks.

PFAS are commonly used because they have water, dirt, stain, and oil repellent properties. For example, they are used in water-resistant and long-lasting cosmetics, and in rugs and upholstery with added stain-resistance. This means that there are many simple ways to lower your exposure, mainly by some lifestyle changes (e.g., by using regular stainless steel pots and not non-stick pots).

A good list of ways to lower your exposure to PFAS and other harmful chemicals, especially if you are pregnant or thinking of pregnancy, or have children. Can also go to ewg.org for lists of personal care products that are PFAS and toxin free.

Nice, short article from The Guardian: Study links in utero ‘forever chemical’ exposure to low sperm count and mobility

A new peer-reviewed Danish study finds that a mother’s exposure to toxic PFAS “forever chemicals” during early pregnancy can lead to lower sperm count and quality later in her child’s life.  ...continue reading "Study Finds “Forever Chemical” Exposure Early in Life Has Effects On Sperm In Adulthood"

For a while now it has been known that some dental floss, such as Oral-B Glide, contain harmful chemical compounds called PFAS (per- and polyfluoroalkyl substances), similar to Teflon. These chemicals have all sorts of negative health effects, and are referred to as "forever chemicals" because they stick around.

A recent investigation by ehn.org (Environmental Health News) and Mamavation (a health/wellness site) tested 39 different brands of dental floss for PFAS by an EPA-certified laboratory. They found evidence of PFAS in one third of the samples, with levels ranging from 11 parts per million (ppm) to 248,900 ppm. Yup, it was Oral-B Glide with the incredibly high levels of PFAS.

These PFAS chemical compounds are linked to all sorts of health problems (e.g. kidney and testicular cancer, semen quality, thyroid disease, immune system effects, reproductive problems, and lowered sex and growth hormones in children) - so you want to avoid them if possible.

It turns out these chemicals are shed into the person's mouth when flossing if the floss contains PFAS, and can be measured in a person's blood.

The four floss brands with extremely high levels (over 70,000 ppm) were: Oral B Glide, Up & Up (Target brand) Smooth Slide Floss, Colgate Total Waxed Dental Floss, and Solimo (Amazon brand) Extra Comfort Dental Floss.

One piece of good news: No dental (tooth) floss marketed to children that they tested had indications of PFAS forever chemicals.

Bottom line: avoid non-stick smooth dental floss such as Oral-B Glide dental floss (or when the dental floss label brags that it is similar to Glide dental floss). Use plain waxed or unwaxed floss instead (e.g., Reach Waxed Floss, Tom's of Maine Floss). Look at the investigation results for brands to avoid and better choices.

From Environmental Health News (EHN.org): Tests find PFAS abundant ​in some dental floss

That nice waxy glide as you floss your teeth? Turns out it could be courtesy of PFAS, the "forever chemicals" that hijacks hormones and is linked to reproductive problems, birth defects, testicular cancer and a host of other diseases. 
...continue reading "Some Dental Floss Brands Contain Harmful PFAS Chemicals"