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Category: brain

Published on Leave a comment on Diet and Risk of Developing Dementia

One message keeps being supported by research: Eat a diet rich in fruits, vegetables, seeds, nuts, whole grains, legumes, and olive oil. A reason is because this diet is anti-inflammatory. And it turns out that inflammation is at the root of many diseases, including heart disease. And dementia.

A recent study that followed more than 84,342 older adults (60 years or older at the start of the study) found that those who ate an anti-inflammatory diet had a 21% lower chance of developing dementia. They also had larger gray matter volume in the brain, and smaller white matter lesions or spots in the brain (white matter hyperintensity volume). All of the adults had cardiometabolic diseases (e.g., heart disease, diabetes, stroke) at the start of the study.

Other studies have already confirmed that eating an anti-inflammatory diet (e.g., Mediterranean diet) is linked to lower risk of diabetes, heart disease, lower dementia risk, better cognitive function, and better brain aging (as measured by MRI scans).

From Medical Xpress: Anti-inflammatory diet could lower your odds for dementia

Eating a healthy diet that dampens inflammation in the body could lower your odds for dementia, especially if you already have heart risk factors, a new Swedish study shows. ...continue reading "Diet and Risk of Developing Dementia"

Published on Leave a comment on Brain Damage From Repeated Blast Exposures During Military Training

We've known for a while that the head trauma from playing football can lead to the degenerative brain disease chronic traumatic encephalopathy (CTE). Now it turns out that some (many?) US Navy SEALS also have an unusual pattern of brain damage. It is traumatic brain injury due to repeatedly being exposed to blast waves, which occur from firing their own weapons or enemy action.

In 2016 a team of doctors put a name to the pattern of brain damage - interface astroglial scarring. It can result in such symptoms as gaps in memory, deteriorating memory, mood swings, headaches, impulsiveness, fatigue, and anxiety. The brain damage is not found in the brains of civilians, or in people exposed to a single massive explosion (e.g., from a roadside bomb). It is not PTSD (post traumatic stress disorder).

Unfortunately, at least 12 former Navy SEALS with this brain damage have committed suicide in the past decade. They were an average age of 43. None of them had been wounded by enemy fire, but all had spent years firing a wide variety of weapons and using explosives.

Many SEALS now alive say they are suffering from the same set of symptoms showing deteriorating brain function. A recent study confirmed this - the more blast exposure, the more symptoms and brain injury.

It is unknown how the military will deal with this issue, and whether and how training of SEALS will change.

Excerpts from an excellent article. Also read the online comments after the article. From NY Times: Pattern of Brain Damage Is Pervasive in Navy SEALs Who Died by Suicide

David Metcalf’s last act in life was an attempt to send a message — that years as a Navy SEAL had left his brain so damaged that he could barely recognize himself.

He died by suicide in his garage in North Carolina in 2019, after nearly 20 years in the Navy. But just before he died, he arranged a stack of books about brain injury by his side, and taped a note to the door that read, in part, “Gaps in memory, failing recognition, mood swings, headaches, impulsiveness, fatigue, anxiety, and paranoia were not who I was, but have become who I am. Each is worsening.” ...continue reading "Brain Damage From Repeated Blast Exposures During Military Training"

Published on Leave a comment on Raw Milk In Europe May Contain A Serious Virus

The CDC currently recommends only consuming pasteurized or ultra-pasteurized milk and dairy products. This is because heating milk kills off the bird flu virus (H5N1) now circulating among dairy cows in the USA. Another serious virus that pasteurization and ultra-pasteurization of milk kills off is the tick-borne encephalitis that occurs throughout central and eastern Europe.

Tick bites are the major way tick-borne encephalitis is spread. But a minority of cases are spread by consuming raw milk or dairy products from recently infected livestock (goats, sheep, and cows).

Tick-borne encephalitis is a serious viral infection of the central nervous system. It starts out with symptoms such as fever, headaches, chills, but up to 39% of cases result in more serious neurological symptoms (meningitis, encephalitis). Infected persons may experience long-term neurological effects lasting years.

Two ways to avoid the tick-borne encephalitis virus: only consuming pasteurized milk and dairy products (and avoiding raw milk and dairy products) or getting vaccinated with the tick-borne encephalitis vaccine (TicoVac, TBE vaccine).

Bottom line: Only consume pasteurized or ultra-pasteurized milk and dairy products.

From article (page 3) in Medscape: Fast Five Quiz: Diagnose and Treat Tick-Borne Illnesses

Tick-borne encephalitis virus can be transmitted by ticks and the alimentary tract. A recent meta-analysis of 410 foodborne tick-borne encephalitis cases, mostly from a region in central and eastern Europe, aimed to describe cases of tick-borne encephalitis acquired through alimentary transmission in Europe from 1980 to 2021. ...continue reading "Raw Milk In Europe May Contain A Serious Virus"

Published on Leave a comment on Daily Olive Oil Consumption Lowers Risk of Developing Dementia

For good health, eating a variety of foods is best. But some foods, such as olive oil, seem to be especially beneficial. A recent study found that high olive oil consumption lowers the risk of developing dementia, perhaps due to its anti-inflammatory properties and improving vascular health.

The large long-term study found that high olive oil consumption significantly decreased rates of developing and dying with dementia. Consuming at least half a tablespoon (7 grams) of olive oil was associated with a 28% lower risk for dementia-related death. And it didn't matter what the rest of the diet was.

Even replacing one teaspoon of margarine or mayonnaise with olive oil was beneficial - about 8 to 14% lower chances of dying with dementia. By the way, both margarine and mayonnaise are ultra-processed foods (look at the ingredients!).

Other benefits of olive oil: it lowers the risk of developing cardiovascular disease, is anti-inflammatory, and helps preserve cognitive health as a person ages (it's neuroprotective).

Research finds that for health benefits, best is extra virgin olive oil (EVOO). Extra virgin olive oil is anti-inflammatory and contains oleocanthal, which has anticancer effects. Health benefits are both if eaten as is (e.g., dunk bread, in salad dressings) or cooked (e.g. roast vegetables, in sauces, cooking foods).

From Medical Xpress: Study suggests daily consumption of olive oil reduces chances of developing dementia

A team of nutritionists and medical researchers at the Harvard T.H. Chan School of Public Health has found evidence that daily consumption of olive oil may reduce the chances of developing dementia. ...continue reading "Daily Olive Oil Consumption Lowers Risk of Developing Dementia"

Published on Leave a comment on Foods That Promote Healthy Brain Aging

Brains age as a person ages. Brains shrink a little over time, and thinking may not be a good as it was years ago. So you absolutely want to delay brain aging and cognitive decline. A recent study found that specific foods and nutrients promote healthy brain aging (delayed brain aging).

The Univ. of Nebraska-Lincoln and Univ. of Illinois researchers looked at a group of 100 healthy individuals (aged 65 to 75 years) and found that they fell into 2 groups: one group with accelerated brain aging and another group with delayed or slower than expected brain aging. They took blood tests and looked for specific nutritional biomarkers, they took MRI scans of the brain, gave questionnaires, and gave cognitive tests.

They found that certain nutrients, food groups, and foods are associated with healthier brains (delayed brain aging). One should eat a diet rich in fruits, vegetables, seeds, nuts, as well as dairy and choline rich foods (e.g., eggs). The beneficial combination of nutrients fall into 3 main groups, with especially good sources given:

1) Fatty acids (vaccenic, gondoic, alpha linolenic, elcosapentaenoic, eicosadienoic and lignoceric acids - found in different foods) a) Fish and shellfish, flaxseed, hemp seed, olive oil, soya oil, canola oil, chia seeds, pumpkin seeds, sunflower seeds, leafy vegetables, and walnuts. b) Peanuts, macadamia nuts, and certain seed oils. c) Dairy products, such as milk, butter, and yogurt.

2) Carotenoids - Spinach, kale, corn, bell peppers (red, green, or yellow), tomatoes, watermelon, grapefruit, cantaloupe, broccoli, and carrots.

3) Vitamins (especially vitamin E and choline) Vitamin E - Nuts, seeds, and vegetable oils, but also significant amounts come from green leafy vegetables and fortified cereals. Choline - Meat, poultry, fish, and eggs, as well as cruciferous vegetables and certain beans.

By the way, this study was part of an emerging field called Nutritional Cognitive Neuroscience. Other studies also find that choline and elements of a Mediterranean style diet appear to be best for healthy brain aging.

From Science Daily: Food for thought: Study links key nutrients with slower brain aging

Scientists have long been studying the brain with a goal of aiding healthier aging. While much is known about risk factors for accelerated brain aging, less has been uncovered to identify ways to prevent cognitive decline. ...continue reading "Foods That Promote Healthy Brain Aging"

Published on Leave a comment on Forever Chemicals Can Enter and Accumulate In the Brain

The toxic chemicals PFAS, commonly referred to as "forever chemicals" (due to their buildup and persistence in people and the environment) are in the news again. Once again, it's bad news. This time, researchers found that PFAS chemicals travel through the blood, and enter and accumulate in the human brain.

And not just the original PFAS chemicals (e.g., used in Teflon, Scotchgard), but even their replacements accumulate in the brain.

PFAS (Per- and polyfluoroalkyl substances) are called forever chemicals due to their buildup and persistence in people and the environment. They are in all of us at varying levels, and they have harmful health effects. Effects include cancer, reproductive harm (e.g., poorer semen quality), birth defects, lowered sex and growth hormones in children, thyroid disease, immune effects, and liver and kidney damage. They are endocrine disruptors.

The chemical industry would have you think that the newer PFAS chemicals that replace the older ones are "safer", but guess what? They're not. They're very similar chemically, so it shouldn't be surprising that they don't appear to be safer.

Bottom line: You can't totally avoid PFAS chemicals, but you can lower your exposure to them. If possible, avoid products that are water and stain proof or leak-proof, especially if children will be using the product. Don't use nonstick cookware, stain resistant carpeting and fabrics, clothing treated to be water-proof, and synthetic turf. PFAS don't have to be mentioned on labels, so it's buyer beware.

From Environmental Health News: PFAS can enter and accumulate in the brain, study confirms

A new study published in Environment International examines the ability of PFAS - a class of hazardous chemicals with known neurotoxic effects - to bypass the body’s protective barriers and enter into brain tissue. ...continue reading "Forever Chemicals Can Enter and Accumulate In the Brain"

Published on Leave a comment on The EPA Reverses Course and Now Proposes Banning Toxic Pesticide

Update to the toxic pesticide acephate story of last week. Well, well, well.... Due to the big outcry after ProPublica's story exposing EPA's recent decision to relax standards and so allow much more of the toxic pesticide acephate in our food, the officials at the EPA changed their minds and now propose banning it! 

Acephate is an insect killer commonly used on celery, lettuce, cauliflower, tomatoes, peppers, and other fruits and vegetables, and residues stay on produce that we eat. It also contaminates drinking water. (It's used on non-organic crops, but it's not allowed to be used on organic crops.)

Propublica's story broke on April 24, 2024, and immediately afterwards there was outrage over the EPA's relaxing of the pesticide standards decision. This is because the FDA was totally ignoring years of scientific and medical research showing harms to humans, and only accepting and believing what the pesticide industry told them. It even ignored its own scientists and advisory groups.

Acephate is a pesticide known to be so harmful that it was BANNED in Europe more than 20 years ago, yet allowed in the US. A major reason: harmful effects on the developing brains of fetuses and children, and linked to autism, hyperactivity, and reduced scores on intelligence tests. In 2023, the CDC said that autism spectrum disorder rates have now increased to 1 out of every  36 births.

Now we wait and see: Will the FDA (once again) cave to industry or actually do what they are supposed to do - protect consumers? 

ProPublica is a non-profit investigative journalism site. The following are excerpts from their May 1, 2024 story on the FDA reversal. From ProPublica: EPA Proposes Ban on Pesticide Widely Used on Fruits and Vegetables

The Environmental Protection Agency unveiled a proposal this week to ban a controversial pesticide that is widely used on celery, tomatoes and other fruits and vegetables. ...continue reading "The EPA Reverses Course and Now Proposes Banning Toxic Pesticide"

Published on Leave a comment on Has Deer Chronic Wasting Disease Occurred In Humans?

Well, it finally might have occurred. The always fatal neurologic disease known as chronic wasting disease (CWD),  which occurs in deer, elk, and moose, and is slowly spreading throughout the US and Canada, may have finally made the jump from deer to humans. This is very worrisome.

CWD is a prion disease similar to "mad cow disease" (bovine spongiform encephalopathy) in cattle and Creutzfeldt-Jakob's disease in humans. There is no vaccine, treatment, or cure for the disease.

In the recently published study, two friends, who hunted and consumed venison from an area known to have chronic wasting disease in the deer population - both died from Creutzfeldt-Jakob disease (CJD) in 2022. Doctors think this is might be a case of "cross-species prion transmission".

So far CWD has been detected in 33 states and several Canadian provinces, and so far nothing has been found to eliminate or slow down the spread of the disease. High heat, disinfection, radiation - these don't kill the CWD prions.

How is it spread? Scientists believe CWD prions spread between animals through body fluids (e.g., feces, saliva, blood, or urine), either through direct contact or indirectly through environmental contamination of soil, food or water. Once introduced into an area or farm, the CWD prion (protein) is contagious within deer and elk populations and spreads.

Once CWD gets into the soil, it stays there for years, and so animals can contract it even after infected deer and elk have died. Recent research found that plants uptake the prions, where it remains infectious.

From Medical Xpress: Consumption of contaminated venison suspected in cases of deer hunters with prion disease

A small team of medical workers and researchers in the U.S. has published a case study of two men, both deer hunters, who developed a rare prion disease. In their study, published in the journal Neurology, the group describes the symptoms of the two patients and how they died.

...continue reading "Has Deer Chronic Wasting Disease Occurred In Humans?"

Published on Leave a comment on Pesticides and Other Chemicals Stored in Home Garages Linked to ALS Risk

For a while now researchers have been finding that certain environmental chemical exposures are linked to the development of amyotrophic lateral sclerosis (ALS), which is commonly called Lou Gehrig's disease. Frequent exposure to pesticides and heavy metal and VOC exposure in solvents (e.g., in woodworking) are linked to ALS.

A recent study found that storing chemicals such as gasoline, kerosene, gasoline-powered equipment, lawn care pesticides, paint, and woodworking chemicals in an attached home garage is also linked to a higher risk for ALS. These are toxic chemicals that are volatile - get into the air.

The researchers felt that not only did the persons with ALS have a history of exposure by working with the chemicals, the chemicals also leach into the air when stored in the home (the attached garage). Every time the door to the garage is opened, the chemicals in the garage air rush into the home.

Earlier studies found higher amounts of pesticides in people with ALS, as well as faster disease progression. Certain pesticides show up repeatedly in studies, including 2,4-D, glyphosate, carbaryl, and chlorpyrifos. Note that 2,4-D is in popular feed and weed products (and was in Agent Orange), and glyphosate is in the commonly used Roundup.

ALS is a progressive and fatal neurodegenerative disease. There is progressive loss of motor neurons, the nerve cells in the brain and spinal cord that control voluntary muscle movement and breathing.

From Science Daily: Chemicals stored in home garages linked to ALS risk

Over the last decade, researchers at University of Michigan continue to find that exposure to environmental toxins -- from pesticides used in agriculture to volatile organic compounds in the manufacturing industry -- is linked to the development of amyotrophic lateral sclerosis, or ALS. ...continue reading "Pesticides and Other Chemicals Stored in Home Garages Linked to ALS Risk"

Published on Leave a comment on Human Brains Are Getting Larger Over Time

Human brains are getting larger each decade. That's the conclusion of researchers conducting the large Framingham Heart study which has now gone on for 75 years.

Between 1999 and 2019 the researchers conducted MRIs on participants born from the 1930s to the 1970s, with participants having an average age of 57. They found that each decade the brain volume steadily increased, with the brains of people born in the 1970s having 6.6% more volume than those born in the 1930s. Brain surface area increased about 15% in that time.

Brain structures such as white matter, gray matter, and hippocampus (a brain region involved in learning and memory) also increased in size over time. This increase in brain volume clearly shows that environmental factors (e.g., nutrition, education, social), and not just genetic factors, influence brain size.

The researchers thought that a larger brain volume, which signifies brain health,  might be protective against Alzheimer's disease. And that this could explain why the percentage of people (the incidence) of Alzheimer's disease and dementia has gone down over time.

From Medical Xpress: Human brains are getting larger: That may be good news for dementia risk

A new study by researchers at UC Davis Health found human brains are getting larger. Study participants born in the 1970s had 6.6% larger brain volumes and almost 15% larger brain surface area than those born in the 1930s. ...continue reading "Human Brains Are Getting Larger Over Time"