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Category: pregnancy and childbirth

Published on Leave a comment on Testing For Syphilis Is Important During Pregnancy

Congenital syphilis rates are rising in the United States. This is when a pregnant woman has syphilis and transmits it to the developing baby (fetus). It results in serious long-term problems for the baby (e.g., stillbirth, deformities, neurological problems, hearing loss) .

Syphilis is an infection caused by the bacterium Treponema pallidum that is treated with antibiotics. Thus congenital syphilis is totally preventable. This is why it is important to do screening and treating for syphilis early in pregnancy.

A study looking at congenital syphilis cases in Mississippi found that cases occur when a pregnant woman doesn't get screened during pregnancy for syphilis, or doesn't receive proper prenatal care. Another risk factor is drug use by the mother. The mother should be screened for syphilis in early pregnancy, and then treated with antibiotics if syphilis is found.

Some states have had a bigger increase than others, especially southwestern and southern states such as Mississippi. It is one of the states that did not require  screening for syphilis in pregnancy, which only became a requirement in Mississippi starting March 2023.

From Medical Xpress: Congenital syphilis rates are soaring, but resources to stem infections are lacking

States are seeing an alarming surge in cases of congenital syphilis, a preventable infection that can lead to miscarriage, stillbirth, newborn death—or lifelong complications such as blindness or deafness. ...continue reading "Testing For Syphilis Is Important During Pregnancy"

Published on Leave a comment on Postpartum Depression In New Fathers

A recent small study discussed the issue of postpartum depression in new fathers, and whether all fathers of newborns should be screened for it. Most people know that women can develop postpartum depression, but the possibility that fathers can also have it is rarely discussed.

In this small study conducted in Chicago, they found that 30% of the 24 fathers appeared to have postpartum depression - based on the same screening tool that is commonly used to screen new mothers. Other studies found/estimated that 8 to 13% of new fathers have postpartum depression, but with much higher rates if the new mother has postpartum depression.

Yes - new fathers can be stressed, anxious, worried, depressed, especially if there are financial or other stressors. Lack of sleep and fatigue was a big contributor to symptoms in the study. Pre-existing mental conditions. Problems with the relationship. Lack of paid parental leave. And on and on.

Both new mothers and new fathers need support after the birth of a baby.

From Science Daily: Should fathers be screened for postpartum depression? Pilot study

Dads can suffer from postpartum depression, and a new pilot study at the University of Illinois Chicago suggests they can and should be screened for the condition. Given the intertwined effects of mothers' and fathers' physical and mental health, addressing the health of fathers may be a powerful untapped tool in improving the nation's ongoing maternal health crisis. ...continue reading "Postpartum Depression In New Fathers"

Published on Leave a comment on Observing Human Ovulation
Egg emerging from the follicle on the ovary. Credit: Jacques Donnez

Today I saw some amazing photos that capture the moment of human ovulation. One can clearly see the egg emerging from a follicle on the ovary. Fertile women release one or more eggs each month.

The photos were taken in 2008 when Dr. Jacques Donnez was performing a hysterectomy on a 45 year old woman and saw that ovulation was occurring. The ovulation he witnessed took about 15 minutes.

By the way, it was the first time human ovulation was caught on camera.

Credit: Jacques Donnez

From June 11, 2008 BBC News: Ovulation moment caught on camera

A human egg has been filmed in close-up emerging from the ovary for the first time, captured by chance during a routine operation. 

Fertile women release one or more eggs every month, but until now, only animal ovulation has been recorded in detail. ...continue reading "Observing Human Ovulation"

Published on Leave a comment on Large Study Finds That Breastfed Babies Less Likely To Die In Their First Year
Breastfeeding
Credit: Wikimedia Commons/ Anton Nosik

Breast milk is beneficial a number of ways. For example, it provides some micronutrients to the baby that formula doesn't provide. It also transmits hundreds of microbial species from the mother to the baby - thus important for the baby's microbiome.

Additionally, recent research found that breastfed babies are 33% less likely to die in the first year of life. This is a huge difference! The researchers looked at data for nearly 10 million infants born in 2016 to 2018, and who were then followed for 1 year after birth.

Studies also find that breastfeeding protects against sudden infant death syndrome and necrotizing enterocolitis in preterm infants.

Bottom line: Breastfeeding should be supported and encouraged. As the study researchers point out: "breastfeeding confers a protective benefit during the first year of life".

From Science Daily: Breastfeeding is associated with a 33% reduction in first-year post-perinatal infant mortality

Among nearly 10 million US infants born between 2016 and 2018, breastfed babies were 33% less likely to die during the post-perinatal period (day 7-364) than infants who were not breastfed, reports a new study in the American Journal of Preventive Medicine, published by Elsevier. The findings build on previous US research with smaller datasets, which documented the association between the initiation of breastfeeding and the reduction of post-perinatal infant mortality by a range of 19% to 26%. ...continue reading "Large Study Finds That Breastfed Babies Less Likely To Die In Their First Year"

Published on Leave a comment on Breast Milk Contains Important Micronutrient For Brain Development
Breastfeeding
Credit: Wikimedia Commons/ Anton Nosik

Another new micronutrient has been discovered in breast milk. This is a sugar molecule called myo-inositol that promotes brain development in infants.

Researchers found that this sugar molecule is most abundant in human breastmilk early after birth when neuronal connections are rapidly forming in the infant brain. Three weeks after birth the levels found in breast milk slowly start to decrease.

This micronutrient was found in breast milk from women at all three study sites (Mexico City, Shanghai, and Cincinnati) - and at similar levels. The researchers stated that this could be one of the reasons why breast milk is so beneficial for a baby's brain development.

Interestingly, adults get myo-inositol from foods, with an adult eating a Western diet getting about 1 gram per day. It is also produced in the brain and other organs. It is especially abundant in fruits (e.g., cantaloupe and oranges), beans, grains, and nuts.

From Medical Xpress: Sugar molecule found in breast milk boosts infant brain development

Breast milk is not simply sustenance. It also is rich in micronutrients that are critical for healthy brain development in infants. ...continue reading "Breast Milk Contains Important Micronutrient For Brain Development"

Published on Leave a comment on Technique May Improve the Microbiome of C-section Babies

Recent studies suggest that "vaginal seeding " of a newborn is effective and also has beneficial health effects for the baby. Vaginal seeding is transferring some of a mother's vaginal fluids (which contain beneficial microbes) onto newborns delivered via C-section.

The reason for doing this procedure (using gauze pads) is because during a vaginal birth the baby picks up the mother's microbes as it moves through the birth canal (this is good!). Babies delivered by C-section don't pick up all these beneficial microbes - instead they get what is floating around the delivery room.

Rutgers Univ. researchers found that infants that received vaginal seeding hosted a different microbial population in their stool and skin (more like the mother's) than those who didn't in the first month after birth. The vaginal seeding had worked - the mother's microbes had become part of the baby's microbiome.

Maria Gloria Dominguez-Bello has been doing research in the area of vaginal seeding and infant microbiome for a while. (Description of vaginal seeding method she uses.)

By the way, breastfeeding the baby is also a great way to transfer maternal microbes to the baby. There are hundreds of species in the breast milk, and the species in the milk vary over time.

From Medical Xpress: Technique may restore healthy bacterial balance in C-section babies

Newborns delivered by cesarean section who are swabbed with the vaginal fluid of their mothers after birth have beneficial bacteria restored to their skin surface and stools, according to a new study.  ...continue reading "Technique May Improve the Microbiome of C-section Babies"

Published on Leave a comment on A Good Diet Is Associated With Lower Rates Of Miscarriage

It absolutely makes sense that a good diet before and during pregnancy is associated with better pregnancy outcomes, including the risk for miscarriage.

Researchers at the University of Birmingham reviewed 20 studies (for a total of 63,838 women) and found that a good diet with healthy foods (both preconception and during pregnancy) is linked to a lower chance of miscarriage. On the other hand, a diet high in processed foods was associated with a doubling of miscarriage risk. Interestingly, higher intake of fried foods and a lower intake of chocolate is also associated with higher miscarriage odds.

What is a "good diet" linked to lower risk of miscarriage? One that is rich in fruits, vegetables, dairy, eggs, and seafood. A high intake of fruits was linked to 61% reduction of miscarriage risk, high intake of vegetables had a 41% reduction, dairy was linked to a 37% reduction, and consumption of eggs had a 19% reduction. Seafood (fish) had a 19% reduction.

Hmmm.... overall the results sound like Mediterranean-style or healthy Nordic foods diets are beneficial. By the way, the researchers were unable to draw any conclusions regarding meat, red meat, white meat, fat, and oil.

There are many reasons for the lower rate of miscarriage with a healthy, whole foods diet: from an increased intake of all sorts of nutrients (vitamins, minerals, flavanols, etc.), rich in anti-oxidants, less oxidative stress, lower rates of inflammation, boosts the immune system, to feeding beneficial microbes in our gut microbiome.

Fun fact: the developing fetus can taste the foods the mother eats.

From Medical Xpress: Diet high in fruit and vegetables linked to lower miscarriage risk

A preconception and early-pregnancy diet that contains lots of fruit, vegetables, seafood, dairy, eggs and grain may be associated with reducing risk of miscarriage, a new review of research suggests. ...continue reading "A Good Diet Is Associated With Lower Rates Of Miscarriage"

Published on Leave a comment on Autism Spectrum Disorder Rates Hit New High
Child Credit: Wikipedia

The CDC reports that autism (autism spectrum disorder) rates are still increasing in the US, from 1 in 150 twenty years ago to 1 in 36 children in 2020. That's huge!

It's not just better screening and diagnosis. Rates are increasing so rapidly that researchers agree that there are environmental factors going on. But what are they?

The researchers of the report point out known factors (e.g., age of parents, multiple gestation birth, prematurity, genetics), but what is not discussed are all the chemical toxins in our environment that people are exposed to both prenatally and after birth (postnatally). Studies find that pregnant women are exposed to more harmful industrial chemicals nowadays than ever before.

For example, lead, heavy metals, and pesticides. People use pesticides in the home, on home exteriors, in their gardens and lawns, on pets, on crops, they're in foods we eat, in water we drink, even in rainfall (!). Millions of pounds are used each year in the US. Many of them have neurological effects.

This means that babies and young children are also exposed to more pesticides than ever before. The American Academy of Pediatrics has been warning about the dangers of pesticide exposure in children for years.

Excerpts from Futurity (site for research news from universities): United States autism rates hit new high

More children have been diagnosed with autism than at any time since monitoring began more than two decades ago, according to new federal studies. About 4% of 8-year-old boys and 1% of 8-year-old girls, in the United States have autism, according to the US Centers for Disease Control and Prevention (CDC). ...continue reading "Autism Spectrum Disorder Rates Hit New High"

Published on Leave a comment on Reduce the Risk of Food Allergies By Having Pet Dogs or Cats

A number of studies in the past decade found that exposure to furry pets (e.g., cats, dogs) in  the first year of a child's life is important for preventing later allergies (animal, food, pollen). A recent large study from Japan found that exposure to pet cats and dogs during pregnancy (developing fetus) and the first year of life confirms that furry pet exposure is important in reducing the risk of food allergies until at least 3 years of age.

While pet dogs kept inside had a protective effect, pet dogs kept outside did not. Also, the type of pet was important. Indoor pet dog exposure reduced the number of children with egg, milk, and nut allergies, while cat exposure was associated with fewer egg, wheat, and soybean allergies. However, these beneficial results did not apply to pet hamsters, birds, and turtles.

Why is this happening? It's thought that early in life exposure to furry pets (dander, microbes) helps train the developing immune system. Their gut microbes also have differences. By the way, other studies found that exposing a child in the first year of life to potential problem foods (e.g., peanut butter, eggs) reduces the incidence of that specific food allergy.

From Science Daily: Living with pet cats or dogs is associated with fewer food allergies in young children, study finds

In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other children, according to a study published March 29, 2023 in the open-access journal PLOS ONE by Hisao Okabe from the Fukushima Regional Center for the Japan Environment and Children's Study, Japan, and colleagues. ...continue reading "Reduce the Risk of Food Allergies By Having Pet Dogs or Cats"

Published on Leave a comment on Group of Researchers Claim That the Fetus Does Not Have A Microbiome

Whether a developing baby (the fetus) has a microbiome or whether it is sterile during pregnancy and only gets "seeded" by microbes from the mother during birth is still being hotly debated. For years it was thought that the fetus and placenta were sterile (no microbes), but then several studies said there is evidence for the fetus and placenta having a microbiome (community of microbes).

Recently an international group of researchers stated that NO, there is no fetal microbiome. They reviewed current evidence, and according to their opinion - a healthy fetus is sterile. Instead, they suggest that the  microbes some researchers found were due to contamination when the samples were taken or during analysis.

We'll see how this all develops. Science is always evolving, with new findings, and lots of debate and controversy.

From Medical Xpress: Expert analysis refutes claims that humans are colonized by bacteria before birth

Scientific claims that babies harbor live bacteria while still in the womb are inaccurate, and may have impeded research progress, according to University College Cork (UCC) researchers at APC Microbiome Ireland, a world-leading Science Foundation Ireland (SFI) Research Center, which led a perspective published today in the journal Nature. ...continue reading "Group of Researchers Claim That the Fetus Does Not Have A Microbiome"