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Published on Leave a comment on Male Fertility Is Plunging In Switzerland

Two years ago scientists reported an alarming and steep decline in sperm counts in men from Western industrialized countries over the last 40 years. Both sperm count and sperm concentration declined 50 to 60% in this period in men in North America, Europe, Australia, and New Zealand. Especially concerning was that there was no evidence of this year by year decline leveling off.

What does this mean? As these declines continue, more and more men will have sperm counts below the point at which they can reproduce. Instead they will be infertile or "sub-fertile" (fertilization is unlikely). According to the World Health Organization (WHO), a sperm count of below 15 million per ml makes a man subfertile. However, also of concern is the threshold level associated with a "decreased monthly probability of conception", which is 40 million/ml - which means conception will take significantly longer (due to impaired ability to fertilize an egg).

A recent Univ. of Geneva study looked at semen quality of 2523 young men (aged 18 to 22 years old) who were being drafted into the military in Switzerland. They found that average sperm quality and sperm concentration of the men, who were from all regions of Switzerland, was among the lowest in Europe (along with Germany, Denmark, and Norway).

In Europe, median sperm count ranges from 41 to 67 million per milliliter (ml), depending on the country. The researchers found that the group of Swiss men had a median sperm count of 48 million per ml. And 17 percent of the men had sperm counts below 15 million per ml (thus subfertile). By the way, countries with lower sperm counts and quality, have higher rates of testicular cancer - they go hand in hand.

Also, in a quarter of the Swiss men studied, less than 40 percent of sperm cells were motile (moved normally), and 43 percent of men had less than 4 percent normally formed sperm. Overall, only 38 percent of Swiss men had healthy sperm - that is, with concentration, motility, and morphology (shape, form) that met the WHO’s criteria for healthy sperm.

Why is this happening? The researchers found that of the men with very low sperm concentration, more of their mothers smoked during the pregnancy, which means there could be changes during embryonic development. Also, while this study did not discuss this, many other researchers say that sperm health is "the canary in the mine" for male health - evidence of harm to men from environmental and lifestyle influences. 

These Western developed countries are awash in chemicals and plastics, also with endocrine disruptors (hormone disruptors) in our foods, our personal care products, in products all around us - and so studies find these chemicals in all of us (in varying degrees). Same with flame retardants, pesticides, "scented" products. Exposure to all sorts of environmental pollutants - whether in air, water, soil, our food - such as high levels of aluminum. All of these can have an effect on sperm counts and reproductive health. You can't totally avoid these chemicals, but you can try to lower your amounts of exposure (some tips to lower exposures).

From Medical Xpress: Poor semen quality in Switzerland   ...continue reading "Male Fertility Is Plunging In Switzerland"

Published on Leave a comment on Getting Nutrients From Food (But Not Supplements) Linked to Lower Risk of Death

Eat real foods, not supplements. Study after study has found beneficial health effects from eating real foods, but not from taking supplements. Now another large study found similar effects - eating real foods was linked to a lower risk of death for any reason (all cause mortality) and death from heart disease (cardiovascular), which was not found with supplements. The only dietary supplement that was associated with a lower risk of death and cancer was lycopene.

In fact, the Tufts University researchers also found that excess intake of calcium from supplements (exceeding 1,000 mg/day) was associated with a 62% increased risk for dying from cancer, but this was not found with foods. And even in persons with a low intake of nutrients from foods, the use of dietary supplements had no effect on the risk of death.The study conclusions were that: "Use of dietary supplements is not associated with mortality benefits among U.S. adults."

From Medical Xpress: Nutrients from food, not supplements, linked to lower risks of death, cancer

...continue reading "Getting Nutrients From Food (But Not Supplements) Linked to Lower Risk of Death"

Published on Leave a comment on Why Do Medical Guidelines Vary So Much?

Are you aware that other countries do not recommend all the tests and screenings that medical specialty organizations in the U.S. recommend? Medical panels in different parts of the world may issue guidelines that vary from U.S. medical specialty guidelines, and sometimes even conflict with them. This is happening even though all groups in various countries are looking at the same medical evidence on which to base recommendations.

This is because in the United States (unlike European countries and Canada) there is a fee for service medical system - the more tests, screenings, and procedures, the more a doctor is paid. Conflict of interest? Bias? Of course. Does it make for better care for patients? Based on the evidence - no.

Interestingly, independent medical groups in the U.S. (such as the U.S. Preventive Services Task Force) that don't have financial interests in the medical services at stake recommend guidelines that are more in line with Canadian and European country guidelines. The U.S. Preventive Services Task Force is an "independent, volunteer panel of national experts in disease prevention and evidence-based medicine".

As many have pointed out, the approach recommended by medical specialty groups of more and more tests and screening leads to  overdiagnosis, overtreatment, and increasing health care costs. There also is specialty bias - which means whatever the physician is trained in, they are biased toward recommending those treatments and procedures. [Similarly, Dr. John Mandrola has written about the issue of employers evaluating physicians on the number of tests and procedures done (with the more, the better the evaluation), and on the harms that can result from screening, tests, and procedures.]

Dr. Ismail Jatoi (Univ. of Texas Health) and Dr. Sunita Sah (at Cornell) have written a thought provoking article in the Canadian Medical Association Journal about these issues with a call to reduce these conflicts when medical organizations give medical guidelines. The panels should be multidisciplinary in composition, independent of specialty societies, and avoid fee-for-service conflicts of interest.

From Science Daily: Medical guidelines may be biased, overly aggressive in US ...continue reading "Why Do Medical Guidelines Vary So Much?"

Published on Leave a comment on Do You Eat Foods With Nanoparticles In Them?

How frequently do you eat foods with nanoparticles in them? The use of nanoparticles in foods is increasing every year, with the result that people may eat foods with them daily (thus having chronic exposure). Nanoparticles in foods are ingredients so small that they are measured in nanometers or billionths of one meter.

The most common nanoparticle is the food additive titanium dioxide, which in Europe is known as E171. Titanium dioxide is added to many processed foods, candy, and even supplements  and non-prescription medicines (e.g. antihistamines) as a "coloring" to make foods whiter or brighter. Currently there are no restrictions on using titanium dioxide nanoparticles in foods.

We still know very little about whether titanium dioxide nanoparticles have health risks to humans, but studies suggest they may cause intestinal inflammation, may disrupt gut microbes, and may migrate to other parts of the body.

Now another study is raising more questions about the safety of titanium dioxide in food. It was done in mice, but the researchers feel it applies to humans. The researchers found that titanium dioxide resulted in a "pro-inflammatory environment and biofilm formation" in the intestines of the mice, and in this way could predispose humans to conditions such as inflammatory bowel disease and colorectal cancer. Bottom line: Read food ingredient lists!

From Science  Daily: Common food additive found to affect gut microbiota

...continue reading "Do You Eat Foods With Nanoparticles In Them?"

Published on Leave a comment on Almost All Americans Have Pesticide Residues In Their Bodies

Did you know that over 90% of all Americans have pesticide residues in their bodies? How do we know this? From studies and from the Centers for Disease Control and Prevention (CDC) which does biomonitoring of large groups of Americans in order to measure pesticides (and other toxic environmental chemicals) in their bodies.

Biomonitoring tells us the "body burden" of toxic chemicals, usually by measuring them in our blood and urine, but also in hair, breast milk and meconium (an infant's first feces gives a measure of prenatal exposure to pesticides). Biomonitoring studies have detected hundreds of different chemicals (including many pesticides) in people, and shown that every single person has a mixture of many contaminants in their body.

The bad news is that we don't really know what all these chronic low level mixtures of pesticides are doing to us. Studies are finding health problems (e.g. various cancers, endocrine disruption, neurological and reproductive problems, even semen quality) with pesticide exposures - especially during pregnancy (the developing fetus), and during childhood. We're talking about pesticide exposures of ordinary people, living ordinary lives, in cities, suburbs, and rural areas.

How do pesticides get into us? Pesticides get into us from inhalation, through the skin, and through ingestion (foods, water).

Studies find that conventionally grown fruits and vegetables are good ways to ingest pesticides, and with more of these foods eaten, the higher the pesticide residue levels in the body. Unfortunately, as more and more pesticides such as fungicides, glyphosate and 2,4-D are used on crops, our exposures and levels of these pesticides in our bodies are increasing.

When our homes, our gardens, and lawns are treated with pesticides, we also get exposed to pesticides. We track them from the outside, and children (and pets) play in them on treated lawns. We are exposed to pesticide "drift" from neighboring properties. Pesticides used inside the house stay in the house dust (they don't break down easily in homes). Pesticides are even found in rain and fog. Scary, isn't it?

Can we lower the levels of pesticides in our bodies? Absolutely yes. Eat as many organic foods as possible - the levels of pesticide residues in the body (as measured in the blood and urine) will go down rapidly. Study after study shows this. A study even found an association with eating organic foods and a lower cancer rate. Don't use pesticides on lawns. Think of weeds as "native grasses" and clover as beneficial. When dealing with indoor pest problems, use least-toxic Integrated Pest Management.

A nice discussion of this is in a recent article by journalist Liza Gross. Excerpts from The Nation: More Than 90 Percent of Americans Have Pesticides or Their Byproducts in Their Bodies

...continue reading "Almost All Americans Have Pesticide Residues In Their Bodies"

Published on Leave a comment on Add Cherries To Your Diet

Another study finds beneficial health effects from eating real foods - this time eating Montmorency tart cherries reduces blood pressure and insulin levels up to 5 hours after ingestion. Of course. It was a small study done in the United Kingdom, with only 11 middle-aged participants, all with metabolic syndrome (increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels). It is estimated that about a third of U.S. adults have metabolic syndrome, which significantly increases the risk of cardiovascular disease and type 2 diabetes.

It was a nicely designed study, and the Montmorency tart cherries were taken in either juice form or capsules which contained freeze-dried Montmorency tart cherry powder. Drinking the juice had slightly better health effects than the freeze dried capsules. It would have been nice if they had also looked at a group of people eating fresh Montmorency tart cherries, rather than just juice or freeze dried cherries.

Keep in mind that this study found positive health effects from real food. However, in contrast, studies find that taking supplements and vitamins generally don't result in health benefits (e.g. calcium, omega-3, niacin, antioxidants), and can even cause harm - unless one has a nutritional deficiency. Studies also don't find that there are "superfoods" - instead, what is beneficial or not is the overall dietary pattern. Studies show that a diet rich in fruits, vegetables, whole grains, nuts, seeds, and legumes has many health benefits (something along the line of the Mediterranean dietary pattern). Try to eat a variety of fruits and vegetables - each has different micronutrients, and even different microbes (good!). Eating that way also results in a high fiber intake, which has many health benefits.

From EurekAlert!: Montmorency tart cherries may provide benefits for adults with metabolic syndrome

Montmorency tart cherries reduced systolic blood pressure, insulin levels and insulin concentrations in adults with metabolic syndrome participating in a small pilot study published in the Journal of Functional Foods.  ...continue reading "Add Cherries To Your Diet"

Published on Leave a comment on Sunscreen Chemicals Enter the Bloodstream

A recent study found that within hours of applying sunscreen, the chemicals in the sunscreen appear in the person's blood - and at levels high enough to be of concern. Of course the chemicals enter the body! Why is anyone surprised? Generally, assume that what you put or get on your skin enters your body - lotions, pesticides, etc.

The small study was conducted by the Center for Drug Evaluation and Research, which is a part of the US Food and Drug Administration (FDA). Commonly available sunscreens (2 different sprays, a lotion, and a cream) were applied on 24 volunteers according to directions. Within hours the four sunscreen ingredients being studied (avobenzone, oxybenzone, ecamsule and octocrylene) had entered the bloodstream at levels high enough to cause concern.  They also found that the blood concentration of three of the ingredients continued to rise as daily use continued and then remained in the body for at least 24 hours after sunscreen use ended.

The four chemicals studied are among a dozen chemicals that the FDA recently said needed to be researched by manufacturers before they could be considered "generally regarded as safe and effective." Especially worrisome is oxybenzone, which is in 85% of chemically based sunscreens - and has also been found in breast milk, amniotic fluid, urine, and blood. It is an endocrine disruptor, and linked to various health problems. With these chemicals, the more one uses, the more gets into the body - and people may apply sunscreen several times a day. They may also be found in personal care products and cosmetics. But unfortunately, as with so many chemicals that we are exposed to - long-term effects of frequent or chronic exposure are unknown.

The Environmental Working Group (EWG) rates sunscreen chemicals and is an excellent resource in finding safe sunscreens, as well as those that should be avoided. The EWG has a page discussing the problems with these chemicals, including that they are endocrine disruptors. They also have a page on nanoparticles (typically zinc and titanium dioxide), which are also used in sunscreens.ided. The EWG has a page discussing the problems with these chemicals, including that they are endocrine disruptors. They also have a page on nanoparticles (typically zinc and titanium dioxide), which are also used in sunscreens.

...continue reading "Sunscreen Chemicals Enter the Bloodstream"

Published on Leave a comment on Could Antibiotics treat Endometriosis??

Could this be true for humans - that antibiotics can treat endometriosis? A nicely done series of studies found that treatment with the antibiotic metronidazole reduced both early growth and progression of endometrial lesions. Also, the researchers found microbiome (community of microbes) differences in endometriosis vs healthy  subjects. The researchers felt that the research results suggest that gut bacteria promote endometriosis progression, and that the antibiotics worked to stop the progression of endometriosis because it reduced specific gut bacteria.

Endometriosis is a chronic condition causing abdominal pain and infertility and afflicts up to 10% of women between the ages of 25 and 40. Unfortunately, current treatments , including hormone therapy and surgery, have serious side effects and do not prevent recurrences. So a study finding another treatment approach is exciting. But...before everyone gets too excited, keep in mind that the series of studies were done in mice, but... the researchers of the study are optimistic that this could be true for women also. And yes, the Washington University School of Medicine (in St. Louis, Missouri) researchers are going to  conduct a large clinical trial to test the antibiotic metronidazole in women with endometriosis.

From Medical Xpress: Antibiotics may treat endometriosis

Researchers at Washington University School of Medicine in St. Louis have found, in mice, that treatment with an antibiotic reduces the size of lesions caused by endometriosis. The researchers are planning a large, multicenter clinical trial to test the drug metronidazole in women who have the painful condition.  ...continue reading "Could Antibiotics treat Endometriosis??"

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Published on 1 Comment on Exposure to Pets in Infancy Reduces the Risk of Allergies

Study after study is finding that having pets in early childhood or living on a farm with lots of exposure to animals is associated with a lower incidence of allergies. Pets with all their "germs" (bacteria and other microbes) appear to have beneficial effects on children's developing immune systems. One study from the Univ. of Gothenburg (in Sweden) actually found that the more pets a child lives with in the first year of life, the lower the incidence of later allergies in children. The results were dose-dependent - with each additional pet, the incidence of allergies is a little lower.

The numbers are amazing - allergies decreased from 49% in those with no pets to zero in those with five or more pets. The researchers suggest that there is  a “mini-farm” effect, with exposure to a number of cats and dogs protecting against all allergy development (animal, food, and pollen allergies). What an about face in medical views in a few decades! It used to be viewed that if you wanted to prevent allergies in children, then avoid pets such as dogs and cats. Hah!

From Medical Xpress: Pet-keeping in early life reduces the risk of allergy in a dose-dependent fashion

A team of researchers at the University of Gothenburg has found that when infants live with pets, they grow up to have fewer allergies and other diseases. In their paper published on the open access site PLOS ONE, the group describes their study of datasets that held information on children's health and whether they had lived with pets as infants, and what they found.  ...continue reading "Exposure to Pets in Infancy Reduces the Risk of Allergies"

Published on Leave a comment on Is A Poor Sense of Smell In Older Adults A Sign of Deteriorating Health?

A number of studies have found that a poor sense of smell in older adults is linked to health problems (especially Parkinson's disease and dementia) and death. Now a recent study found that a poor sense of smell in older adults is associated with an almost 50% increase in their risk of dying within 10 years—especially in individuals reporting good health. In other words, a poor sense of smell is an early sign of deteriorating health, even when it is not apparent yet to the person.

Researchers at  the Michigan State Univ. College of Human Medicine  followed 2,289 persons (aged 71 to 82) for 13 years. The generally healthy persons took a smell test of 12 common odors (e.g. onion, soap, gasoline, lemon, chocolate and rose) at the start of the study, and were scored as having good, moderate, or poor sense of smell. After 13 years 1,211 of them had died. The researchers then looked to see if there was any association between scores on the smell test and their risk of death at various points over the 13 years.

No association was found at the three- or five-year mark of the study. But those with a poor sense of smell had a 46 percent higher risk of dying by 10 years and a 30 percent higher risk by 13 years, when compared with the older adults with a good sense of smell. The researchers believe the risk was lower at 13 years because so many of the participants had already died - whether their ability to smell was initially good or poor. So how to interpret the study results? It appears that a poor sense of smell may be a sensitive early sign of deteriorating health, even when it is not apparent yet.

From Medical Xpress: Poor sense of smell associated with nearly 50 percent higher risk for death in 10 years  ...continue reading "Is A Poor Sense of Smell In Older Adults A Sign of Deteriorating Health?"