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Once again research finds that endocrine disruptors are associated with health effects - this time with earlier puberty in girlsEndocrine disruptors are chemicals that interfere with the body's endocrine (or hormone) systems and can produce all sorts of negative health effects, including all sorts of reproductive problems in both males and females. Phthalates, parabens, and phenols (all used in common everyday products) are examples of endocrine disruptors.

The researchers asked the question: Is a baby's exposure before birth or exposure around the time of puberty (peripuberty) to phthalates, parabens, and phenols (which are found in personal care products) associated with the timing of when he or she starts puberty? In other words, does the mother's exposure to these chemicals during pregnancy have an effect on the fetus, which then has an effect years later on the child's puberty? And how about peripubertal exposure? The answer is a strong YES for girls, and minimal effect on boys (but boys did have earlier genital development with propyl paraben exposure).

What is scary is that almost all women (and men) are exposed to these chemicals - which can be measured in the urine. Studies find these chemicals in over 96% of American women. What to do?  One can't totally escape these chemicals, but one can really minimize exposure by reading labels and avoiding personal care products that list phthalates, parabens, phenols, as well as Triclosan (found in some anti-bacterial soaps). Avoid products that include "fragrances" or "scents" (those have a multitude of chemicals in them, including endocrine disruptors). Avoid air fresheners, dryer sheets, scented candles, room deodorizers, essential oils (lavender, tea tree oil). Buy "unscented" or "fragrance free" products.

The good news is that once a person avoids these chemicals, the levels in the body go down. So it's worth the effort minimizing exposure to them. By the way, animal studies find numerous reproductive effects from these chemicals, including timing of puberty. From Medical Xpress:

Chemicals in personal care and household products linked to earlier puberty in girls

Chemicals that are widely used in personal care and household products are linked to girls entering puberty at earlier ages, according to findings from a long-running study of mothers and children published today. The study in Human Reproduction, one of the world's leading reproductive medicine journals, found that chemicals such as phthalates, parabens and phenols were all associated with earlier puberty in girls, although there was no similar association observed in boys.   

...continue reading "Personal Care Products and Puberty"

Are bacteria living in healthy human brains? It has long been thought that the brain is protected by the blood-brain barrier, that the brain is sterile (bacteria are not normally there), and if there are bacteria in the brain, then that means a serious disease (e.g. meningitis).  However, the research team of Rosalind Roberts, Charlene Farmer, and Courtney Walker (at the University of Alabama) found bacteria in the brains they studied with electron microscopes.

The brains showed no inflammation (thus the bacteria were not pathogenic), and modern tests (genetic sequencing) showed that they were gut bacteria. Which  means they got there from the gut. If further research supports their findings, then this would be a paradigm shift -  a new way of thinking about the brain and microbes.

Two good articles discuss this research - the first is in Science, and the second is a fascinating interview of Rosalind Roberts about this research. Excerpts from the article written by Michael Segal in Nautilus:

Are There Bacteria in Your Brain?

...continue reading "Are Bacteria Living In Healthy Brains?"

Pregnant women have been advised to keep their consumption of coffee and other caffeinated beverages (tea, sodas, cocoa, energy drinks), and chocolate containing foods to a minimum for decades. Currently the American College of Obstetrics recommends that women consume less than 200 mg of caffeine (from any source) per day during pregnancy. This is less than 2 cups of regular coffee  or 4 cups of regular black tea. But a recent  study's findings suggest that the levels should be kept much lower.

The study of 941 mother/baby pairs in Ireland found that each 100 mg increase of caffeine per day was associated with a lower birth weight, shorter length of pregnancy (gestational age), shorter birth length of the baby, and smaller head circumference of the baby at birth. The strongest associations between those who consumed the most caffeine (when compared to those who consumed the least) was with lower birth weight.

The researchers think this occurs because caffeine crosses the placenta easily, but during pregnancy there is a slowed metabolism of caffeine (so it takes longer to get it out of the body). Similar results have been found in other recent studies. [On the other hand, for not pregnant women - coffee and tea are linked to all sorts of health benefits - here, here.]

From Medical Xpress: Caffeinated beverages during pregnancy linked to lower birth weight babies

...continue reading "Keep Caffeine To A Minimum During Pregnancy"

Very interesting - that infections may be a trigger for a coronary heart disease event such as heart attack or ischemic stroke, within the next 3 months. [Ischemic strokes are strokes caused by a blood clot.] A recent study found that the association held for both inpatient (in hospital) and outpatient infections, but was stronger for inpatient infections . The most common infections before a heart attack or stroke were urinary tract infections (≈29%), pneumonia/respiratory infections (≈27%), skin and subcutaneous infections, and blood infections.

From Medical Xpress: Infections may be a trigger for heart attack, stroke

Diabetes, high blood pressure and elevated cholesterol are well-known risk factors for cardiovascular disease. But what about just getting sick? Could picking up some type of bug increase your chance of having a stroke or heart attack?  A new study suggests it could. 

...continue reading "Infections A Trigger For Heart Attack Or Stroke?"

Another reason to eat fruits and vegetables daily - cognitive and memory functioning in later life. A large US study of 27,842 men found that a higher intake of fruits, vegetables, and orange juice for many years is linked to a lower risk of poor cognitive functioning in later years of life (70s and beyond). The study specifically looked at subjective cognitive function - a measure of earliest changes in cognitive functioning, including memory. This is the stage before "mild cognitive impairment". The study started in 1986 when the average age was 51 years, and continued till 2012. The men studied were all health professionals (e.g. dentists)

What was a high intake of fruits and vegetables? For vegetables: about 5.7 servings per day (while the lowest intake was 1.7 servings per day). For fruit: high intake was 3.1 servings per day (vs lowest intake was .5 servings per day). For fruit juice (orange juice): high intake was 1.5 servings per day (vs lowest intake was .1 servings per day). A serving of fruit is considered one cup of fruit or ½ cup of fruit juice. A serving of vegetables is considered one cup of raw vegetables or two cups of leafy greens.

The researchers found that green leafy vegetables, carotenoid-rich vegetables (esp. tomatoes and peppers), cantalope, berries, and orange juice to be especially protective. They point out that many antioxidant nutrients and bioactive substances (including vitamins A,B, C, and E, carotenoids, flavonoids, and polyphenols) are all found naturally in vegetables, fruits, and juices. These are thought to reduce brain oxidative stress, improve cognitive performance, and to prevent neuronal damage. In other words, all good things for the brain. From Science Daily:

Orange juice, leafy greens and berries may be tied to decreased memory loss in men

Eating leafy greens, dark orange and red vegetables and berry fruits, and drinking orange juice may be associated with a lower risk of memory loss over time in men, according to a study published in the November 21, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.  ...continue reading "Eat Fruits And Vegetables Every Day!"

In the US and other developed countries it is generally accepted that blood pressure increases with age -  that a blood pressure rise starts in childhood and that it's a normal part of aging. However, a new study found that this is not true - a South American rainforest tribe (the Yanomami) who do not eat a western diet (at all!) and have an active lifestyle, have the exact same blood pressure throughout life. This was true for all the individuals studied - from age 1 to 60. A nearby village of the Yekwana tribe have some western influences on lifestyle and diet, had the same low blood pressure in childhood, but showed increases with age.

The researchers feel that a Western diet and lifestyle play a role in the blood pressure increasing over the life span. They are now looking at the gut microbes of the two tribes to see what role they have in these blood pressure differences. Bottom line: get off your butt  and get active, and eat a high fiber, whole food diet (to feed the beneficial microbes) -  and avoid highly processed foods if you can. Easier said than done. From Science Daily:

Study of two tribes sheds light on role of Western-influenced diet in blood pressure

...continue reading "Blood Pressure Doesn’t Always Increase With Age"

A benefit (perhaps) of having the appendix taken out in childhood - it is associated with a lower rate of Parkinson's disease decades later in life, according to an international study that looked at health records of 1.7 million people in Sweden. Other main findings is that this finding is especially strong for individuals living in rural areas (and not urban areas), and that removing the appendix also delayed the age of Parkinson's disease onset in those who got the disease. But if you read further, there were other interesting findings in the study, even though much is still unknown - it's still a big puzzle with lots of pieces still to be filled in.

By the way, other recent research also supports the view that Parkinson's disease gets its start in the gut - and not in the brain, which is what everyone thought for years. But note that there are other risk factors such as certain pesticide exposure or drug use, or trauma to the head that are linked to Parkinson's disease. Many studies find that rural living is associated with a higher risk for Parkinson's disease, and it is thought this is probably due to higher exposure to pesticides, which then somehow contributes to the development of Parkinson's disease. From Medical Xpress:

Appendix removal is linked to lower risk of Parkinson's

Scientists have found a new clue that Parkinson's disease may get its start not in the brain but in the gut—maybe in the appendix. People who had their appendix removed early in life had a lower risk of getting the tremor-inducing brain disease decades later, researchers reported Wednesday.

Why? A peek at surgically removed appendix tissue shows this tiny organ, often considered useless, seems to be a storage depot for an abnormal protein—one that, if it somehow makes its way into the brain, becomes a hallmark of Parkinson's ...continue reading "Appendix Removal and Parkinson’s Disease"

Whoa.... a recent study examined food microbiomes (community of microbes) of some foods and found that the foods contained many species of microbes - hundreds of species! The foods examined were a variety of masala spice mixes, cilantro, smoked salmon, cucumbers, and mung bean sprouts.

Other studies have also found large numbers of bacterial species in all sorts of foods, including raw fruits and vegetables, cheeses, and fermented foods, such as kimchi. There are also bacterial differences between conventional and organic foods. No wonder it's good to eat a diverse diet - all those microbes that you're ingesting! A diverse gut microbial community in humans is considered healthy by researchers.

The researchers (all associated with the US FDA - Food and Drug Administration) looked at the bacterial "species richness" (number of different bacterial species) normally found on the 5 types of foods. They used modern genetic sequencing methods to analyze the food microbiomes and found a LOT of bacterial species ("high bacterial diversity"), as well as species unique to the different foods sampled - whether animal or plant based foods.

They found not only beneficial species, but also species associated with food spoilage. Every food had some bacteria that could eventually lead to food spoilage (which makes sense - eventually all foods can spoil). Also, how the food was handled and packaged, as well as moisture levels, influenced the bacterial species found in the foods.

The masala spice mixes were especially rich in bacterial species (from from 968 to 1097) and in unique species (19), but the mixes also contained as many as 17 ingredients. Cucumbers had between 227 and 423 bacterial species, and 216 to 573 species for cilantro. Smoked salmon samples had fewer species - ranging from 89 to 181 species. An example of the diversity is that the cucumber microbiome is comprised of species within Proteobacteria (45 to 85%), Firmicutes (2 to 40%), Actinobacteria (8 to 31%), and Bacteroidetes (0 to 2%).

I don't know if one can ever replenish all the bacteria lost from years of antibiotics (e.g. for sinus infections - both chronic and acute sinusitis), but this is a good reason to eat a variety of foods - for all the species of bacteria. These bacterial species are not found in general probiotic pills - one must eat the foods to ingest the variety and richness of microbes.

The researchers wrote: "Once established, the most likely source of new microbes joining our GI microbiome is the food we eat: each food stuff and commodity we consume likely contains a microbiome that passes through our bodies while nutritional ingredients and components are digested."

It is unknown how many of these microbes stick around in our body, but lots of research finds that a diet rich in fruits, vegetables, whole grains, seeds, nuts, legumes, some fish and meat (including poultry), some dairy - are beneficial to our gut microbiome, along with numerous health benefits. The fiber in these foods is also beneficial in that it feeds beneficial microbes. [see category NUTRITION for research, also Feeding Your Gut Microbes page.]

Excerpts from research by Karen G. jarvis et al in Frontiers In Microbiology:

Microbiomes Associated With Foods From Plant and Animal Sources

...continue reading "Common Foods Contain Hundreds Of Diverse Bacterial Species"

Something to think about: a group of international researchers found a correlation in Brazil between colon cancer and pesticides.

Brazil is one of the largest pesticide users in the world, and annual pesticide use is still increasing - along with increases in colon cancer and colon cancer deaths, especially in agricultural areas. While the study was correlational (didn't prove that pesticides caused the cancer) - what supports the findings is that some other studies in both humans and rodents found that pesticides increase the risk of colon cancer. Many pesticides are considered carcinogenic (cancer-causing).

The researchers pointed out that pesticides are contaminating water and food in Brazil, pesticide residues have been found in breast milk, pesticide residues in cow's milk exceed safety standards in some regions of Brazil, and 20% of food samples analyzed by one government agency between 2013 and 2015 were found to be unsafe for humans to eat due to high pesticide residue levels. One reason for recent  big increases in pesticide used is from genetically modified crops - so that they are resistant to pesticides (herbicides) applied.

Does all this sound familiar? It should - many of the same problems are occurring in the US, with pesticides found in water and food samples, in house dust, with steep increases in certain pesticides used due to their use on crops that are genetically modified to be resistant to pesticides (esp. glyphosate, 2,4-D), and pesticides are found in people (can be measured in blood, urine) - with levels of certain pesticides increasing (e.g. glyphosate).

Think of how casually people use pesticides - on their lawns, gardens, and in their homes. The bottom line is: what are we doing to ourselves with chronic low-level pesticide exposures? And it's not just one pesticide, it's many (so we're actually exposed to mixtures). [See posts on pesticides.]

Excerpts from Beyond Pesticides: Brazilian Researchers Link Rise In Colon Cancer To Increase In Pesticide Use    ...continue reading "Pesticides and Colon Cancer?"

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Probiotics are the future of sinusitis treatment. Research found that a probiotic (beneficial bacteria) that is lacking in those with chronic sinusitis, and which can successfully treat sinusitis is Lactobacillus sakei.

[See June 2022 updated version of this post.] This article is the summary of what has been learned over the past 7 years: the best L. sakei  products (such as kimchi and Lanto Sinus - which can treat even the worst recurring sinus infections, frequently within days), results of people trying various L. sakei products, and other possibilities for sinus health.

Back in 2012, a study by Abreu et al suggested Lactobacillus sakei as a possible treatment for sinusitis. In the past 6 years those conclusions have been supported by the experiences of hundreds of people contacting me, and my family's experiences with L. sakei products. It really is the best sinusitis treatment for most people!

When Lactobacillus sakei works as a treatment - it can seem miraculous as sinusitis symptoms gradually disappear or greatly improve. Many times within a few days! Unfortunately it doesn't work for everyone - for a minority there seems to be no effect, and it is not clear why. It also doesn't treat seasonal allergies or allergy symptoms.

Lactobacillus sakei works best when it is used only when needed, when there are sinus symptoms. No boosters needed when feeling well! (See Treatment Summary page for different ways to use products.)

The sinus microbiome is the community of microbes (bacteria, viruses, fungi) that live in the sinuses. This community can become disrupted and imbalanced (dysbiosis) from illnesses, allergies, or antibiotics and cause a sinus infection or sinusitis.

Research in the last decade has found that not only do sinusitis sufferers lack L. sakei, they have too much of some other bacteria, and they don't have the bacteria diversity in their sinuses that healthy people without sinusitis have. There is a depletion of some bacterial species, and an increase in "abundance" of other species.

Luckily Lactobacillus sakei is found in some foods (such as some brands of live fermented kimchi), some sausage starter cultures (such as B-2), and recently in some probiotic supplements (e.g. Lanto Sinus). One reason it is used in sausage starter cultures is because L. sakei dominates over and inhibits growth of pathogenic bacteria, including Staphylococcus aureus.

BACKGROUND STORY: Seven years ago there were no probiotics containing L. sakei. None. So instead members of my family experimented using a very easy kimchi sinusitis treatment (basically dabbing and smearing kimchi at certain stages of fermentation into the nostrils like a very messy eater) and found that it cured  chronic sinusitis of many years within several weeks. Obviously it contained L. sakei. It felt miraculous, especially because it was so easy to do.

After 7 years we still feel great! Because we no longer have chronic sinusitis and can easily treat sinusitis if it occurs with L. sakei, we have NOT taken antibiotics or any other bacteria killing spray or product (such as xylitol) for over 6 years. We do not use cortisone or antihistamine nasal sprays either.

WHEN A TREATMENT WORKS: Many of you have contacted me to report your own progress with various sinusitis treatments. People used terms such as "miraculous", "transformative", and "fabulous" when they had positive results with a product containing L. sakei.

When a treatment works, then all sinusitis symptoms go away  or there is major improvement - frequently within a few days. Symptoms that go away include post nasal drip, sinus headaches, "clogged ears", bad breath, and sinusitis-related coughs. Even tonsil stones! (Please note: trying products to treat sinusitis is self-experimentation - effects can be positive or negative. Always be cautious. Best results are to use L. sakei only when needed.)

OVERALL RESULTSThe majority of people contacting me with results reported positive results (chronic sinusitis greatly improved or totally gone) from some form of L. sakei treatment. Successes have been from the USA, Canada, Europe, Australia, New Zealand, Japan, and Africa. Since it's from self-experimentation and not a clinical trial, I don't know the actual percentage of positive results.

Some of the people reporting success have had multiple operations, some currently have deviated septums, some with nasal polyps, and all have had long-standing chronic sinusitis, some for decades.

Chronic sinusitis sufferers also reported that the same treatments also worked to treat acute sinusitis. It seems that after colds, etc. many develop acute sinusitis again and need re-treatment (the L. sakei frequently doesn't stay in the sinuses from earlier treatments). However, the sinuses do continue improving over time, so fewer and more minimal treatments (perhaps only a few days) are needed over time.

Another very small group reported that other probiotic strains helped (but it is not always clear whether they also tried a L. sakei product), and minority of people reported that nothing has helped and there could be a variety of reasons for this (see below). Some people reported that one product helped, but not another - whether kimchi or a L. sakei product.

THREE MAIN PRODUCT CATEGORIES: Products containing live Lactobacillus sakei which people have reported success in treating sinusitis: kimchi (and some sauerkraut), refrigerated products (e.g. Lanto Sinus), and frozen products. Note that currently the FDA does not allow any probiotics to be sold as a medical treatment – they can only be sold as a supplement.

Using the following products to treat sinusitis is self-experimentation (results are unknown and can vary). Always be cautious. (See Sinusitis Treament Summary page for methods.)

KIMCHI - Many people report that kimchi helped them. And one person reported a homemade kimchi worked great (he was finally symptom free after many years). A few have even mentioned that kimchi has helped sinusitis with fungal problems.

Kimchi brands that people reported helping their chronic sinusitis: Sunja's Kimchi (medium spicy cucumber kimchi and mild white kimchi), Sinto Gourmet brand kimchiMama-O's Premium Kimchi, the white Napa kimchi and cabbage kimchi made by Choi's Kimchi Company, Farmhouse Culture Kimchi, Mother-in-law's KimchiOzuke Kimchi, in the United Kingdom the brand Mr Kimchi, and in Australia Kehoe's Kitchen white kimchi.

[Finding a kimchi brand with L. sakei is due to self-experimentation. The kimchi must be live, and not pasteurized. We found that kimchi may contain L. sakei from about day 14 (or earlier) to about 2 to 2 1/2 months (from the day it's made.]

When the kimchi contained L. sakei we felt the same or started feeling better within one or 2 days. If we felt more mucusy over the next 2 days, or the acute sinusitis kept getting worse, than it did not contain L. sakei. Researchers feel that it's the garlic in kimchi that encourages L. sakei growth.

SAUERKRAUT - Sauerkraut has worked for some people if it is sauerkraut made with garlic, such as some varieties of Cleveland Kraut. Researchers feel that it's the garlic in kimchi that encourages L. sakei growth, and traditional sauerkraut typically doesn't contain garlic.

REFRIGERATED LACTOBACILLUS SAKEI PRODUCTS  – A high-quality refrigerated L. sakei product specifically meant for the sinuses and treatment of sinusitis is sold by Lanto Health. The kimchi derived Lactobacillus sakei product called Lanto Sinus is meant to be used when needed. Lanto Sinus  holds up well in the refrigerator, is effective, reliable, and easy to use. This product ships well because it holds up for a while (days) without refrigeration.

People have reported success using it mixed with bottled water (dabbing, smearing, spooning a little in nostrils), or swishing it dry in the mouth. I’ve been a consultant with Lanto Health on this product and have been testing and using this product successfully for over 2 years (self-experimentation!).    ...continue reading "The Best Probiotic For Sinus Infections"